DK0619316T3 - Xanthinderivater - Google Patents
XanthinderivaterInfo
- Publication number
- DK0619316T3 DK0619316T3 DK94105380T DK94105380T DK0619316T3 DK 0619316 T3 DK0619316 T3 DK 0619316T3 DK 94105380 T DK94105380 T DK 94105380T DK 94105380 T DK94105380 T DK 94105380T DK 0619316 T3 DK0619316 T3 DK 0619316T3
- Authority
- DK
- Denmark
- Prior art keywords
- effect
- substituted
- hydroxy
- oxo
- chem
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D473/00—Heterocyclic compounds containing purine ring systems
- C07D473/02—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
- C07D473/04—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP8084193 | 1993-04-07 | ||
| JP32740593 | 1993-12-24 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK0619316T3 true DK0619316T3 (da) | 1999-02-08 |
Family
ID=26421810
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK94105380T DK0619316T3 (da) | 1993-04-07 | 1994-04-07 | Xanthinderivater |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US5395836A (de) |
| EP (1) | EP0619316B1 (de) |
| AT (1) | ATE169625T1 (de) |
| CA (1) | CA2120677C (de) |
| DE (1) | DE69412322T2 (de) |
| DK (1) | DK0619316T3 (de) |
| ES (1) | ES2121591T3 (de) |
| GR (1) | GR3027681T3 (de) |
Families Citing this family (36)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9312853D0 (en) | 1993-06-22 | 1993-08-04 | Euro Celtique Sa | Chemical compounds |
| CA2167314A1 (en) * | 1994-05-17 | 1995-11-23 | Junichi Shimada | Process for producing xanthine derivative |
| US5922751A (en) | 1994-06-24 | 1999-07-13 | Euro-Celtique, S.A. | Aryl pyrazole compound for inhibiting phosphodiesterase IV and methods of using same |
| US5591776A (en) | 1994-06-24 | 1997-01-07 | Euro-Celtique, S.A. | Pheynl or benzyl-substituted rolipram-based compounds for and method of inhibiting phosphodiesterase IV |
| EP0799040B1 (de) | 1994-12-13 | 2003-08-20 | Euroceltique S.A. | Dreifachsubstituierte thioxanthine |
| DE69531506T2 (de) | 1994-12-13 | 2004-06-24 | Euroceltique S.A. | Arylthioxanthine |
| US5830839A (en) | 1995-05-17 | 1998-11-03 | Sunburst Chemicals, Inc. | Solid detergents with active enzymes and bleach |
| US6166041A (en) | 1995-10-11 | 2000-12-26 | Euro-Celtique, S.A. | 2-heteroaryl and 2-heterocyclic benzoxazoles as PDE IV inhibitors for the treatment of asthma |
| US6075016A (en) | 1996-04-10 | 2000-06-13 | Euro-Celtique S.A. | 6,5-fused aromatic ring systems having enhanced phosphodiesterase IV inhibitory activity |
| US5864037A (en) | 1996-06-06 | 1999-01-26 | Euro-Celtique, S.A. | Methods for the synthesis of chemical compounds having PDE-IV inhibitory activity |
| US6210687B1 (en) * | 1996-08-07 | 2001-04-03 | Kyowa Hakko Kogyo Co., Ltd. | Fat emulsion containing xanthine derivative |
| US5786360A (en) * | 1996-11-19 | 1998-07-28 | Link Technology Incorporated | A1 adenosine receptor antagonists |
| EP0863148A1 (de) * | 1997-03-03 | 1998-09-09 | K.U. Leuven Research & Development | Von Adenosin abgeleitete Verbindungen, Verwendung solcher Verbindungen als Medikament, Verfahren zur Herstellung solcher Verbindungen und Zwischenprodukte dafür |
| AU740770B2 (en) | 1997-06-18 | 2001-11-15 | Aderis Pharmaceuticals, Inc. | Compositions and methods for preventing restenosis following revascularization procedures |
| HUP0203371A3 (en) | 1999-11-12 | 2005-02-28 | Biogen Idec Ma Inc Cambridge | Adenosine receptor antagonists and methods of making and using the same |
| CN100390178C (zh) | 1999-11-12 | 2008-05-28 | 拜奥根Idec马萨诸塞公司 | 作为腺苷受体拮抗剂的多环烷基嘌呤 |
| EP1601649A4 (de) * | 2003-02-19 | 2009-03-04 | Endacea Inc | A1-adenosinrezeptorantagonisten |
| US20040229901A1 (en) * | 2003-02-24 | 2004-11-18 | Lauren Otsuki | Method of treatment of disease using an adenosine A1 receptor antagonist |
| EP1932529A1 (de) | 2003-04-25 | 2008-06-18 | Novacardia, Inc. | Verfahren zur verbesserten Harnausscheidung bei Personen mit beeinträchtiger Nierenfunktion |
| CA2522971A1 (en) * | 2003-04-25 | 2004-11-11 | Novacardia, Inc. | Method of improved diuresis in individuals with impaired renal function |
| US20060293312A1 (en) * | 2003-04-25 | 2006-12-28 | Howard Dittrich | Method of improved diuresis in individuals with impaired renal function |
| US7247639B2 (en) * | 2003-06-06 | 2007-07-24 | Endacea, Inc. | A1 adenosine receptor antagonists |
| US20090068101A9 (en) * | 2003-06-09 | 2009-03-12 | Endacea, Inc. | A1 Adenosine Receptor Antagonists |
| AU2005237466A1 (en) * | 2004-04-16 | 2005-11-10 | Novacardia, Inc. | Combination therapy comprising an adenosine A1 receptor antagonist and an aldosterone inhibitor |
| US8841334B2 (en) | 2006-05-31 | 2014-09-23 | Abbvie Inc. | Compounds as cannabinoid receptor ligands and uses thereof |
| WO2007140439A2 (en) | 2006-05-31 | 2007-12-06 | Abbott Laboratories | Compounds as cannabinoid receptor ligands and uses thereof |
| CN101466383A (zh) * | 2006-06-16 | 2009-06-24 | 美国诺华卡迪亚公司 | 包含低频率投与aa1ra的肾功能延长改善 |
| JP2010522760A (ja) | 2007-03-28 | 2010-07-08 | アボット・ラボラトリーズ | カンナビノイド受容体リガンドとしての１，３−チアゾール−２（３ｈ）−イリデン化合物 |
| WO2008121882A1 (en) * | 2007-03-29 | 2008-10-09 | Novacardia, Inc. | Improved methods of administration of adenosine a1 receptor antagonists |
| WO2008121893A1 (en) * | 2007-03-29 | 2008-10-09 | Novacardia, Inc. | Methods of treating heart failure and renal dysfunction in individuals with an adenosine a1 receptor antagonist |
| US7872033B2 (en) | 2007-04-17 | 2011-01-18 | Abbott Laboratories | Compounds as cannabinoid receptor ligands |
| MX2009012374A (es) | 2007-05-18 | 2009-12-01 | Abbott Lab | Compuestos novedosos como ligandos del receptor de canabinoides. |
| US9193713B2 (en) | 2007-10-12 | 2015-11-24 | Abbvie Inc. | Compounds as cannabinoid receptor ligands |
| US8846730B2 (en) | 2008-09-08 | 2014-09-30 | Abbvie Inc. | Compounds as cannabinoid receptor ligands |
| TW201016692A (en) | 2008-09-16 | 2010-05-01 | Abbott Lab | Novel compounds as cannabinoid receptor ligands |
| PA8854001A1 (es) | 2008-12-16 | 2010-07-27 | Abbott Lab | Compuestos novedosos como ligandos de receptores de canabinoides |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SE416810C (sv) * | 1977-10-14 | 1982-07-19 | Draco Ab | Forfarande for framstellning av xantinderivat med antiallergisk aktivitet |
| US4755517A (en) * | 1986-07-31 | 1988-07-05 | Warner-Lambert Company | Derivatives of xanthine, pharmaceutical compositions and methods of use therefor |
| EP0414175A3 (en) * | 1989-08-22 | 1992-04-01 | Hoechst Aktiengesellschaft | Use of xanthine derivatives to reduce nephrotoxicity |
| JPH06102662B2 (ja) * | 1989-09-01 | 1994-12-14 | 協和醗酵工業株式会社 | キサンチン誘導体 |
| US5290782A (en) * | 1989-09-01 | 1994-03-01 | Kyowa Hakko Kogyo Co., Ltd. | Xanthine derivatives |
| DE69232323T2 (de) * | 1991-01-29 | 2002-08-08 | Fujisawa Pharmaceutical Co., Ltd. | Verwendung von Adenosinantagonisten zur Vorbeugung und Behandlung von Pankreatitis und Ulcera |
| JPH04270222A (ja) * | 1991-02-25 | 1992-09-25 | Kyowa Hakko Kogyo Co Ltd | 脳機能改善剤 |
| CA2061544A1 (en) * | 1991-02-25 | 1992-08-26 | Fumio Suzuki | Xanthine compounds |
| JPH0560354A (ja) * | 1991-09-03 | 1993-03-09 | Osaka Gas Co Ltd | 加熱調理器の換気装置 |
| ATE180482T1 (de) * | 1991-11-08 | 1999-06-15 | Kyowa Hakko Kogyo Kk | Xanthinderivate zur behandlung der demenz |
| US5342841A (en) * | 1992-03-12 | 1994-08-30 | Kyowa Hakko Kogyo Co., Ltd. | Xanthine derivatives |
-
1994
- 1994-04-05 US US08/222,938 patent/US5395836A/en not_active Expired - Lifetime
- 1994-04-06 CA CA002120677A patent/CA2120677C/en not_active Expired - Fee Related
- 1994-04-07 DK DK94105380T patent/DK0619316T3/da active
- 1994-04-07 EP EP94105380A patent/EP0619316B1/de not_active Expired - Lifetime
- 1994-04-07 DE DE69412322T patent/DE69412322T2/de not_active Expired - Fee Related
- 1994-04-07 ES ES94105380T patent/ES2121591T3/es not_active Expired - Lifetime
- 1994-04-07 AT AT94105380T patent/ATE169625T1/de not_active IP Right Cessation
-
1998
- 1998-08-20 GR GR980401857T patent/GR3027681T3/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| CA2120677A1 (en) | 1994-10-08 |
| DE69412322D1 (de) | 1998-09-17 |
| EP0619316A1 (de) | 1994-10-12 |
| ATE169625T1 (de) | 1998-08-15 |
| DE69412322T2 (de) | 1998-12-24 |
| EP0619316B1 (de) | 1998-08-12 |
| ES2121591T3 (es) | 1998-12-01 |
| CA2120677C (en) | 2001-07-03 |
| US5395836A (en) | 1995-03-07 |
| GR3027681T3 (en) | 1998-11-30 |
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