DK0640612T3 - Hidtil ukendte derivater af 2-(1H)-quinolinon, fremgangsmåde til deres fremstilling og farmaceutiske præparater indeholdend - Google Patents

Hidtil ukendte derivater af 2-(1H)-quinolinon, fremgangsmåde til deres fremstilling og farmaceutiske præparater indeholdend

Info

Publication number: DK0640612T3
Authority: DK; Denmark
Prior art keywords: substituted; branched; linear; unsubstituted; group
Prior art date: 1993-08-31

Application number

DK94401926T

Other languages

English (en)

Inventor

Jean Lepagnol

Alex Cordi

Patrice Desos

Original Assignee

Adir

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1993-08-31

Filing date

1994-08-31

Publication date

1999-02-15

1994-08-31 Application filed by Adir filed Critical Adir

1999-02-15 Application granted granted Critical

1999-02-15 Publication of DK0640612T3 publication Critical patent/DK0640612T3/da

Links

239000008194 pharmaceutical composition Substances 0.000 title 1
LISFMEBWQUVKPJ-UHFFFAOYSA-N quinolin-2-ol Chemical class C1=CC=C2NC(=O)C=CC2=C1 LISFMEBWQUVKPJ-UHFFFAOYSA-N 0.000 title 1
125000004169 (C1-C6) alkyl group Chemical group 0.000 abstract 3
125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 3
125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 3
-1 aminosulphonyl group Chemical group 0.000 abstract 2
125000004191 (C1-C6) alkoxy group Chemical group 0.000 abstract 1
125000006700 (C1-C6) alkylthio group Chemical group 0.000 abstract 1
125000006272 (C3-C7) cycloalkyl group Chemical group 0.000 abstract 1
UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
239000002253 acid Substances 0.000 abstract 1
125000000217 alkyl group Chemical group 0.000 abstract 1
125000003277 amino group Chemical group 0.000 abstract 1
125000004432 carbon atom Chemical group C* 0.000 abstract 1
150000001875 compounds Chemical class 0.000 abstract 1
125000004093 cyano group Chemical group *C#N 0.000 abstract 1
239000003814 drug Substances 0.000 abstract 1
125000005843 halogen group Chemical group 0.000 abstract 1
229910052739 hydrogen Inorganic materials 0.000 abstract 1
239000001257 hydrogen Substances 0.000 abstract 1
125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
125000000449 nitro group Chemical group [O-][N+](*)=O 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/553—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having one nitrogen atom as the only ring hetero atom
- C07F9/576—Six-membered rings
- C07F9/5765—Six-membered rings condensed with carbocyclic rings or carbocyclic ring systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/553—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having one nitrogen atom as the only ring hetero atom
- C07F9/576—Six-membered rings
- C07F9/60—Quinoline or hydrogenated quinoline ring systems

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
General Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Medicinal Chemistry (AREA)
Biomedical Technology (AREA)
Pharmacology & Pharmacy (AREA)
General Chemical & Material Sciences (AREA)
Animal Behavior & Ethology (AREA)
Chemical Kinetics & Catalysis (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Neurosurgery (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Neurology (AREA)
Biochemistry (AREA)
Molecular Biology (AREA)
Psychiatry (AREA)
Hospice & Palliative Care (AREA)
Pain & Pain Management (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

DK94401926T 1993-08-31 1994-08-31 Hidtil ukendte derivater af 2-(1H)-quinolinon, fremgangsmåde til deres fremstilling og farmaceutiske præparater indeholdend DK0640612T3 (da)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
FR9310379A FR2709489B1 (fr)	1993-08-31	1993-08-31	Nouveaux dérivés de 2-(1H)-quinoléinone, leur procédé de préparation et les compositions pharmaceutiques qui les contiennent.

Publications (1)

Publication Number	Publication Date
DK0640612T3 true DK0640612T3 (da)	1999-02-15

Family

ID=9450460

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK94401926T DK0640612T3 (da)	1993-08-31	1994-08-31	Hidtil ukendte derivater af 2-(1H)-quinolinon, fremgangsmåde til deres fremstilling og farmaceutiske præparater indeholdend

Country Status (12)

Country	Link
US (2)	US5536709A (da)
EP (1)	EP0640612B1 (da)
JP (1)	JP2672262B2 (da)
AT (1)	ATE165362T1 (da)
AU (1)	AU676348B2 (da)
CA (1)	CA2117600A1 (da)
DE (1)	DE69409734T2 (da)
DK (1)	DK0640612T3 (da)
ES (1)	ES2118343T3 (da)
FR (1)	FR2709489B1 (da)
NZ (1)	NZ264338A (da)
ZA (1)	ZA946659B (da)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JP2000309585A (ja) *	1999-02-26	2000-11-07	Kyorin Pharmaceut Co Ltd	６−置換ヘテロキノリンカルボン酸誘導体とその付加塩及びそれらの製造方法
FR2805260A1 (fr) *	2000-02-18	2001-08-24	Adir	Nouveaux derives d'acides 6-sulfamoyl-3-quinolinyl phosphoniques, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
FR2805262A1 (fr) *	2000-02-18	2001-08-24	Adir	Nouveaux derives d'acides aryle ou heteroaryle quinolinyl phosphoniques, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
FR2805261A1 (fr) *	2000-02-18	2001-08-24	Adir	Nouveaux derives d'acides 6-amino ou 6-hydrazinosulfonyl-3- quinolinyl phosphoniques, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
TWI366565B (en)	2007-06-06	2012-06-21	Otsuka Pharma Co Ltd	Quinolone compound and pharmaceutical composition
US8222431B2 (en) *	2007-10-16	2012-07-17	Janssen Pharmaceutica N.V.	Process for synthesizing phosphonic and phosphinic acid compounds
WO2012164085A1 (en)	2011-06-03	2012-12-06	Merz Pharma Gmbh & Co. Kgaa	Glycine b antagonists
KR102509217B1 (ko) *	2020-08-28	2023-03-14	기초과학연구원	시스테인 선택적 결합 퀴놀리논 유도체 화합물, 이의 펩티드 결합체 및 이를 포함하는 항체-약물 접합체

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4124588A (en) *	1976-03-01	1978-11-07	Sandoz, Inc.	4-Hydroxy-quinolin-2-one-3-phosphonic acid esters
US4093637A (en) *	1977-01-31	1978-06-06	The United States Of America As Represented By The Secretary Of Agriculture	Alkyl 9,9(10,10)-bis(acyloxymethyl)octadecanoates as primary plasticizers for polyvinylchloride
US4906621A (en) *	1985-05-24	1990-03-06	Ciba-Geigy Corporation	Certain 2-carboxypiperidyl-alkylene phosphonic acids and esters thereof useful for the treatment of disorders responsive to N-methyl-D-aspartate receptor blockade
FR2683818B1 (fr) *	1991-11-14	1993-12-31	Adir Cie	Nouveaux derives de 3-sulfonylamino-2-(1h)-quinoleinone, leur procede de preparation et les compositions pharmaceutiques qui les contiennent.
IS4233A (is) *	1993-12-22	1995-06-23	Astra Aktiebolag	Misleit hringtengd efnasambönd

1993
- 1993-08-31 FR FR9310379A patent/FR2709489B1/fr not_active Expired - Fee Related
1994
- 1994-08-29 AU AU71520/94A patent/AU676348B2/en not_active Ceased
- 1994-08-29 CA CA002117600A patent/CA2117600A1/fr not_active Abandoned
- 1994-08-30 US US08/297,793 patent/US5536709A/en not_active Expired - Fee Related
- 1994-08-30 NZ NZ264338A patent/NZ264338A/en unknown
- 1994-08-30 JP JP6205464A patent/JP2672262B2/ja not_active Expired - Fee Related
- 1994-08-31 DK DK94401926T patent/DK0640612T3/da active
- 1994-08-31 AT AT94401926T patent/ATE165362T1/de not_active IP Right Cessation
- 1994-08-31 ZA ZA946659A patent/ZA946659B/xx unknown
- 1994-08-31 EP EP94401926A patent/EP0640612B1/fr not_active Expired - Lifetime
- 1994-08-31 DE DE69409734T patent/DE69409734T2/de not_active Expired - Fee Related
- 1994-08-31 ES ES94401926T patent/ES2118343T3/es not_active Expired - Lifetime
1995
- 1995-07-10 US US08/499,946 patent/US5646132A/en not_active Expired - Fee Related

Also Published As

Publication number	Publication date
ES2118343T3 (es)	1998-09-16
US5536709A (en)	1996-07-16
FR2709489A1 (fr)	1995-03-10
FR2709489B1 (fr)	1995-10-20
CA2117600A1 (fr)	1995-03-01
ZA946659B (en)	1995-04-20
ATE165362T1 (de)	1998-05-15
DE69409734D1 (de)	1998-05-28
EP0640612A1 (fr)	1995-03-01
JPH07149778A (ja)	1995-06-13
US5646132A (en)	1997-07-08
AU7152094A (en)	1995-03-16
DE69409734T2 (de)	1998-11-12
AU676348B2 (en)	1997-03-06
NZ264338A (en)	1995-10-26
EP0640612B1 (fr)	1998-04-22
JP2672262B2 (ja)	1997-11-05

Publication	Publication Date	Title
ATE79376T1 (de)	1992-08-15	Dithioacetal-verbindungen, verfahren zu deren herstellung und diese enthaltende pharmazeutische zusammensetzungen.
DK0447285T3 (da)	1993-08-16	Nephtalenderivater, fremgangsmåde til fremstilling heraf og farmaceutiske midler indeholdende dem
NZ227436A (en)	1992-10-28	Cell proliferation inhibiting composition comprising a substituted styrene derivative
ATE113940T1 (de)	1994-11-15	Aminobenzolsulfonsäurederivate.
AU2835192A (en)	1993-05-20	New 3-sulfonylamino-2(1h)-quinolone compounds, process for preparing them and pharmaceutical compositions containing them
PT99644A (pt)	1992-10-30	Processo para a preparacao de novos derivados de guanidina
NZ221699A (en)	1990-03-27	Pyridazinone derivatives; pharmaceutical compositions and intermediates
AU676348B2 (en)	1997-03-06	New 2(1H)-quinolone compounds, process for their preparationand the pharmaceutical compositions which contain them
ES2010284A6 (es)	1989-11-01	Procedimiento para preparar derivados de tiourea.
HUT59124A (en)	1992-04-28	Process for producing 2-(aminoalkyl)-5-(arylalkyl)-1,3-dioxane derivatives and pharmaceutical compositions comprising such derivatives as active ingredient
ATE3294T1 (de)	1983-05-15	6-aminosubstituierte n-pyrrolyl-3-pyridazinamine, deren herstellung und sie enthaltende pharmazeutische antihypertensive zusammensetzungen.
ES547604A0 (es)	1987-04-01	Un procedimiento para preparar derivados de 2-piridin-tiol
NO932779L (no)	1994-02-07	Tetrahydronaftalenderivater, fremgangsmaate for deres fremstilling og anvendelse derav
ES543781A0 (es)	1986-01-16	Procedimiento de preparacion de un derivado 1,1-difenilpro- pan-1-ol
SE8500963D0 (sv)	1985-02-27	Nitraminodiaryl sulfoxide derivatives, process for their preparation and pharmaceutical and pesticidal compositions containing them
TH37500A (th)	2000-03-06	อนุพันธ์ซิส-ซับสทิทิวเทด ซับสทิทิวเทด อะมิโนไซโคลแอลคิล พิร์โรลิอีน