DK0649537T4 - Immunoassays til anti-HCV-antistoffer, ved anvendelse af antigener med konformationelle epitoper - Google Patents

Immunoassays til anti-HCV-antistoffer, ved anvendelse af antigener med konformationelle epitoper

Info

Publication number
DK0649537T4
DK0649537T4 DK93916942T DK93916942T DK0649537T4 DK 0649537 T4 DK0649537 T4 DK 0649537T4 DK 93916942 T DK93916942 T DK 93916942T DK 93916942 T DK93916942 T DK 93916942T DK 0649537 T4 DK0649537 T4 DK 0649537T4
Authority
DK
Denmark
Prior art keywords
antigens
conformational epitopes
hcv
immunoassays
hcv antibodies
Prior art date
Application number
DK93916942T
Other languages
English (en)
Other versions
DK0649537T3 (da
Inventor
David Y Chien
Original Assignee
Chiron Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=25429280&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK0649537(T4) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Chiron Corp filed Critical Chiron Corp
Publication of DK0649537T3 publication Critical patent/DK0649537T3/da
Application granted granted Critical
Publication of DK0649537T4 publication Critical patent/DK0649537T4/da

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/576—Immunoassay; Biospecific binding assay; Materials therefor for hepatitis
    • G01N33/5767—Immunoassay; Biospecific binding assay; Materials therefor for hepatitis non-A, non-B hepatitis

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Cell Biology (AREA)
  • Communicable Diseases (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Processing And Handling Of Plastics And Other Materials For Molding In General (AREA)
DK93916942T 1992-07-07 1993-07-02 Immunoassays til anti-HCV-antistoffer, ved anvendelse af antigener med konformationelle epitoper DK0649537T4 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US91075992A 1992-07-07 1992-07-07
PCT/US1993/006309 WO1994001778A1 (en) 1992-07-07 1993-07-02 Immunoassays for anti-hcv antibodies using antigens with conformational epitopes

Publications (2)

Publication Number Publication Date
DK0649537T3 DK0649537T3 (da) 2002-06-17
DK0649537T4 true DK0649537T4 (da) 2006-04-10

Family

ID=25429280

Family Applications (1)

Application Number Title Priority Date Filing Date
DK93916942T DK0649537T4 (da) 1992-07-07 1993-07-02 Immunoassays til anti-HCV-antistoffer, ved anvendelse af antigener med konformationelle epitoper

Country Status (19)

Country Link
US (1) US20020150883A1 (da)
EP (1) EP0649537B2 (da)
JP (2) JP3490085B2 (da)
AT (1) ATE216779T1 (da)
AU (1) AU685059B2 (da)
CA (1) CA2139645C (da)
CZ (1) CZ291951B6 (da)
DE (1) DE69331845T3 (da)
DK (1) DK0649537T4 (da)
ES (1) ES2171414T5 (da)
FI (1) FI110546B (da)
HU (1) HUT70473A (da)
NO (1) NO321185B1 (da)
PL (1) PL174686B1 (da)
PT (1) PT649537E (da)
RU (1) RU2126158C1 (da)
SK (1) SK284556B6 (da)
UA (1) UA39944C2 (da)
WO (1) WO1994001778A1 (da)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6274148B1 (en) * 1990-11-08 2001-08-14 Chiron Corporation Hepatitis C virus asialoglycoproteins
US5882852A (en) * 1993-06-29 1999-03-16 The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services Hepatitic C virus (HCV) core gene nucleotide sequences and related methods of detecting major and minor genotypes of HCV isolates
US7070790B1 (en) 1993-06-29 2006-07-04 The United States Of America As Represented By The Department Of Health And Human Services Nucleotide and deduced amino acid sequences of the envelope 1 and core genes of isolates of hepatitis C virus and the use of reagents derived from these sequences in diagnostic methods and vaccines
EP1845108A3 (en) * 1994-07-29 2007-10-24 Innogenetics N.V. Monoclonal antibodies to purified hepatitis c virus envelope proteins for diagnostic and therapeutic use
DE4428705A1 (de) * 1994-08-12 1996-02-15 Boehringer Mannheim Gmbh Rekombinantes Antigen aus der NS3-Region des Hepatitis C Virus
US5707385A (en) * 1994-11-16 1998-01-13 Advanced Cardiovascular Systems, Inc. Drug loaded elastic membrane and method for delivery
WO1996041196A1 (en) * 1995-06-07 1996-12-19 Abbott Laboratories Method for detection of antibody to hepatitis c virus second envelope glycoprotein
US6514731B1 (en) 1996-05-24 2003-02-04 Chiron Corporation Methods for the preparation of hepatitis C virus multiple copy epitope fusion antigens
WO2000026673A1 (en) * 1998-11-03 2000-05-11 Abbott Laboratories Methods of detecting chronic infection caused by hcv
US6815160B1 (en) 1999-07-28 2004-11-09 Chiron Corporation Hepatitis C viral antigen immunoassay detection systems
EP1295126B1 (en) * 1999-07-28 2007-01-24 Novartis Vaccines and Diagnostics, Inc. Hepatitis c viral antigen immunoassay detection systems
EP1829891B1 (en) 2000-06-15 2012-12-26 Novartis Vaccines and Diagnostics, Inc. Immunoassays for Anti-HCV Antibodies
BRPI0111731C1 (pt) 2000-06-15 2021-07-27 Chiron Corp suporte sólido de imunoensaio, métodos de detecção de infecção pelo vírus da hepatite c (hcv) em uma amostra biológica, e de produção de um suporte sólido de imunoensaio, e, kit de teste de imunodiagnóstico
RU2194993C2 (ru) * 2000-12-28 2002-12-20 Научно-исследовательский институт вирусологии им.Д.И.Ивановского РАМН Способы ускоренной диагностики гепатита с, основанные на обнаружении гемагглютининов вируса гепатита с и антител к ним в рга и ртга в крови людей
AR045702A1 (es) 2001-10-03 2005-11-09 Chiron Corp Composiciones de adyuvantes.
RU2192011C1 (ru) * 2001-11-26 2002-10-27 Иткес Александр Веньяминович Набор "микровирус" для обнаружения днк вич, интегрированной в хромосомы инфицированных клеток
ES2312806T3 (es) 2002-09-09 2009-03-01 Novartis Vaccines And Diagnostics, Inc. Ensayo de vhc.
EP1624785B1 (en) * 2003-01-17 2013-07-17 Aethlon Medical, Inc. Method for removal of viruses from blood by lectin affinity hemodialysis
WO2004071414A2 (en) * 2003-02-05 2004-08-26 Genzyme Corporation Therapeutic anti-hcv (al9) compounds
US7731967B2 (en) 2003-04-30 2010-06-08 Novartis Vaccines And Diagnostics, Inc. Compositions for inducing immune responses
EP1799868B1 (en) * 2004-08-27 2012-01-18 Novartis Vaccines and Diagnostics, Inc. Hcv non-structural protein mutants and uses thereof
WO2008024518A2 (en) 2006-08-25 2008-02-28 Novartis Ag Hcv fusion polypeptides
AU2008335457B2 (en) 2007-12-07 2015-04-16 Glaxosmithkline Biologicals S.A. Compositions for inducing immune responses
FR2984328B1 (fr) 2011-12-20 2016-12-30 Bio-Rad Innovations Procede de detection d'une infection par le virus de l'hepatite c
MX362075B (es) 2013-03-14 2019-01-07 Abbott Lab Ensayo de combinación de antígeno-anticuerpo del virus de la hepatitis c (vhc) y métodos y composiciones para usarlo.
CN105378099B (zh) 2013-03-14 2021-05-11 雅培制药有限公司 Hcv核心脂质结合结构域单克隆抗体
WO2014143342A1 (en) 2013-03-14 2014-09-18 Abbott Laboratories Hcv ns3 recombinant antigens and mutants thereof for improved antibody detection
ES2832335T3 (es) 2015-03-27 2021-06-10 Ortho Clinical Diagnostics Inc Polipéptidos NS4A/NS3 modificado del VHC y usos de los mismos

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4855224A (en) * 1984-03-09 1989-08-08 Genentech, Inc. Molecularly cloned diagnostic product and method of use
WO1989004669A1 (en) 1987-11-18 1989-06-01 Chiron Corporation Nanbv diagnostics and vaccines
HUT54896A (en) 1989-03-17 1991-04-29 Chiron Corp Process for producing aquous diagnosticum and vaccine of nanbv
US5372928A (en) * 1989-09-15 1994-12-13 Chiron Corporation Hepatitis C virus isolates
DE4040339C2 (de) * 1989-12-18 1999-07-08 Wellcome Found Virales Agens
ZA912040B (en) * 1990-03-30 1991-12-24 Akzo Nv Peptides immunochemically reactive with antibodies directed against hepatitis non-a,non-b virus
KR100206150B1 (ko) * 1990-04-04 1999-07-01 로버트 피. 블랙버언 항-에이치씨브이 항체에 대한 면역분석용 씨형 간염 바이러스(에이치디브이)항원의 조합체
AU660925B2 (en) * 1990-04-06 1995-07-13 Genelabs Technologies, Inc. Hepatitis C virus epitopes
FI913068A7 (fi) * 1990-06-25 1991-12-26 The Res Foundation For Microbial Ei-A-, ei-B-hepatiittiviruspartikkelit
KR0181517B1 (ko) * 1990-07-09 1999-04-01 나까하라 노부유끼 비-에이 비-비형 간염-특이 항원 및 간염 진단에서 그의 용도
DE69131882T3 (de) * 1990-11-08 2007-05-24 Novartis Vaccines and Diagnostics, Inc., Emeryville Asiloglycoproteine des hepatitis c-virus
IT1249684B (it) * 1991-07-19 1995-03-09 Sorin Biomedica Spa Epitopi della proteina env del virus dell'epatite c.
AU666176B2 (en) * 1992-01-31 1996-02-01 Abbott Laboratories Mammalian expression systems for HCV proteins
US5587285A (en) * 1992-01-31 1996-12-24 University Of Texas System Generation serological assay for monitoring HIV exposure

Also Published As

Publication number Publication date
ES2171414T5 (es) 2006-09-01
US20020150883A1 (en) 2002-10-17
DK0649537T3 (da) 2002-06-17
CZ291951B6 (cs) 2003-06-18
CA2139645C (en) 2003-02-11
ES2171414T3 (es) 2002-09-16
ATE216779T1 (de) 2002-05-15
JP3490085B2 (ja) 2004-01-26
PL307178A1 (en) 1995-05-02
SK495A3 (en) 1995-07-11
JPH07509060A (ja) 1995-10-05
EP0649537A1 (en) 1995-04-26
RU94046284A (ru) 1997-02-27
DE69331845T3 (de) 2006-10-05
CA2139645A1 (en) 1994-01-20
FI950002A0 (fi) 1995-01-02
SK284556B6 (sk) 2005-06-02
RU2126158C1 (ru) 1999-02-10
WO1994001778A1 (en) 1994-01-20
HUT70473A (en) 1995-10-30
EP0649537B2 (en) 2006-02-22
JP2003329687A (ja) 2003-11-19
AU685059B2 (en) 1998-01-15
FI950002L (fi) 1995-02-27
DE69331845D1 (de) 2002-06-06
HU9500008D0 (en) 1995-03-28
FI110546B (fi) 2003-02-14
UA39944C2 (uk) 2001-07-16
NO950006L (no) 1995-02-24
NO950006D0 (no) 1995-01-02
CZ695A3 (en) 1996-03-13
PL174686B1 (pl) 1998-08-31
AU4662993A (en) 1994-01-31
DE69331845T2 (de) 2002-08-14
PT649537E (pt) 2002-09-30
EP0649537B1 (en) 2002-04-24
NO321185B1 (no) 2006-04-03

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