DK0657170T3 - Produkter til anvendelse af høje initialdoser af cetrorelix og fremstilling af en kombinationspakning til anvendelse ved te - Google Patents
Produkter til anvendelse af høje initialdoser af cetrorelix og fremstilling af en kombinationspakning til anvendelse ved teInfo
- Publication number
- DK0657170T3 DK0657170T3 DK94118466T DK94118466T DK0657170T3 DK 0657170 T3 DK0657170 T3 DK 0657170T3 DK 94118466 T DK94118466 T DK 94118466T DK 94118466 T DK94118466 T DK 94118466T DK 0657170 T3 DK0657170 T3 DK 0657170T3
- Authority
- DK
- Denmark
- Prior art keywords
- cetrorelix
- tea
- products
- preparation
- high initial
- Prior art date
Links
- 108700008462 cetrorelix Proteins 0.000 title abstract 4
- 229960003230 cetrorelix Drugs 0.000 title abstract 2
- 241001122767 Theaceae Species 0.000 title 1
- SBNPWPIBESPSIF-MHWMIDJBSA-N cetrorelix Chemical compound C([C@@H](C(=O)N[C@H](CCCNC(N)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N1[C@@H](CCC1)C(=O)N[C@H](C)C(N)=O)NC(=O)[C@H](CO)NC(=O)[C@@H](CC=1C=NC=CC=1)NC(=O)[C@@H](CC=1C=CC(Cl)=CC=1)NC(=O)[C@@H](CC=1C=C2C=CC=CC2=CC=1)NC(C)=O)C1=CC=C(O)C=C1 SBNPWPIBESPSIF-MHWMIDJBSA-N 0.000 title 1
- KFEFLCOCAHJBEA-ANRVCLKPSA-N cetrorelix acetate Chemical compound CC(O)=O.C([C@@H](C(=O)N[C@H](CCCNC(N)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N1[C@@H](CCC1)C(=O)N[C@H](C)C(N)=O)NC(=O)[C@H](CO)NC(=O)[C@@H](CC=1C=NC=CC=1)NC(=O)[C@@H](CC=1C=CC(Cl)=CC=1)NC(=O)[C@@H](CC=1C=C2C=CC=CC2=CC=1)NC(C)=O)C1=CC=C(O)C=C1 KFEFLCOCAHJBEA-ANRVCLKPSA-N 0.000 abstract 3
- 229960001865 cetrorelix acetate Drugs 0.000 abstract 2
- UCANQOXFIYWYIX-IDEADWEOSA-N (2S)-1-[(2S)-2-[[(2S)-2-[[(2R)-2-[[(2S)-2-[[(2S)-2-[[(2R)-2-[[(2R)-2-[[(2R)-2-acetamido-3-naphthalen-2-ylpropanoyl]amino]-3-(4-chlorophenyl)propanoyl]amino]-3-pyridin-3-ylpropanoyl]amino]-3-hydroxypropanoyl]amino]-3-(4-hydroxyphenyl)propanoyl]amino]-5-(carbamoylamino)pentanoyl]amino]-4-methylpentanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]-N-[(2R)-1-amino-1-oxopropan-2-yl]pyrrolidine-2-carboxamide 4-[(3-carboxy-2-hydroxynaphthalen-1-yl)methyl]-3-hydroxynaphthalene-2-carboxylic acid Chemical compound OC(=O)c1cc2ccccc2c(Cc2c(O)c(cc3ccccc23)C(O)=O)c1O.CC(C)C[C@H](NC(=O)[C@@H](CCCNC(N)=O)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CO)NC(=O)[C@@H](Cc1cccnc1)NC(=O)[C@@H](Cc1ccc(Cl)cc1)NC(=O)[C@@H](Cc1ccc2ccccc2c1)NC(C)=O)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N1CCC[C@H]1C(=O)N[C@H](C)C(N)=O.CC(C)C[C@H](NC(=O)[C@@H](CCCNC(N)=O)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CO)NC(=O)[C@@H](Cc1cccnc1)NC(=O)[C@@H](Cc1ccc(Cl)cc1)NC(=O)[C@@H](Cc1ccc2ccccc2c1)NC(C)=O)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N1CCC[C@H]1C(=O)N[C@H](C)C(N)=O UCANQOXFIYWYIX-IDEADWEOSA-N 0.000 abstract 1
- 239000013066 combination product Substances 0.000 abstract 1
- 229940127555 combination product Drugs 0.000 abstract 1
- 238000012423 maintenance Methods 0.000 abstract 1
- 230000003211 malignant effect Effects 0.000 abstract 1
- 239000000047 product Substances 0.000 abstract 1
- 230000001225 therapeutic effect Effects 0.000 abstract 1
- 238000002560 therapeutic procedure Methods 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/08—Peptides having 5 to 11 amino acids
- A61K38/09—Luteinising hormone-releasing hormone [LHRH], i.e. Gonadotropin-releasing hormone [GnRH]; Related peptides
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- Reproductive Health (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Immunology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- General Health & Medical Sciences (AREA)
- Gastroenterology & Hepatology (AREA)
- Endocrinology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medical Preparation Storing Or Oral Administration Devices (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Tea And Coffee (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE4342091A DE4342091A1 (de) | 1993-12-09 | 1993-12-09 | Erzeugnisse zur Anwendung von initial hohen Dosen von Cetrorelix und Herstellung einer Kombinationspackung zur Verwendung bei Therapie von Krankheiten |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK0657170T3 true DK0657170T3 (da) | 2000-07-31 |
Family
ID=6504624
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK94118466T DK0657170T3 (da) | 1993-12-09 | 1994-11-24 | Produkter til anvendelse af høje initialdoser af cetrorelix og fremstilling af en kombinationspakning til anvendelse ved te |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US5663145A (da) |
| EP (1) | EP0657170B1 (da) |
| JP (1) | JP3439855B2 (da) |
| AT (1) | ATE190495T1 (da) |
| CA (1) | CA2137595C (da) |
| DE (2) | DE4342091A1 (da) |
| DK (1) | DK0657170T3 (da) |
| ES (1) | ES2145803T3 (da) |
| GR (1) | GR3033319T3 (da) |
| PT (1) | PT657170E (da) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6828415B2 (en) * | 1993-02-19 | 2004-12-07 | Zentaris Gmbh | Oligopeptide lyophilisate, their preparation and use |
| EP0788799A3 (en) | 1996-02-07 | 1998-10-21 | ASTA Medica Aktiengesellschaft | LHRH-Antagonists in the treatment of fertility disorders |
| DE19644994A1 (de) * | 1996-10-30 | 1998-05-07 | Asta Medica Ag | Diagnostisches Mittel |
| US7005418B1 (en) * | 1999-09-23 | 2006-02-28 | Zentaris Gmbh | Method for the therapeutic management of extrauterine proliferation of endometrial tissue, chronic pelvic pain and fallopian tube obstruction |
| DE10024451A1 (de) * | 2000-05-18 | 2001-11-29 | Asta Medica Ag | Pharmazeutische Darreichungsform für Peptide, Verfahren zu deren Herstellung und Verwendung |
| DE10137174A1 (de) * | 2001-07-31 | 2003-02-13 | Zentaris Ag | Verwendung von LHRH-Antagonisten in nichtkastrierenden Dosen zur Verbesserung der T-Zellen-vermittelten Immunität |
| US20040138138A1 (en) * | 2001-08-02 | 2004-07-15 | Jurgen Engel | Use of LHRH-antagonists in doses that do not cause castration for the improvement of T-cell mediated immunity |
| BRPI0314546B8 (pt) * | 2002-09-27 | 2021-05-25 | Zentaris Gmbh | composição de gel farmacêutico compreendendo peptídeos farmaceuticamente atvos com liberação sustentada, método para a produção dos mesmos kit. |
| US20040224000A1 (en) * | 2003-05-05 | 2004-11-11 | Romano Deghenghi | Implants for non-radioactive brachytherapy of hormonal-insensitive cancers |
| EP1674082A1 (de) * | 2004-12-22 | 2006-06-28 | Zentaris GmbH | Verfahren zur Herstellung von sterilen Suspensionen oder Lyophilisaten schwerlöslicher basischer Peptidkomplexe, diese enthaltende pharmazeutische Formulierungen sowie ihre Verwendung als Arzneimittel |
| EP1891964A1 (en) * | 2006-08-08 | 2008-02-27 | AEterna Zentaris GmbH | Application of initial doses of LHRH analogues and maintenance doses of LHRH antagonists for the treatment of hormone-dependent cancers and corresponding pharmaceutical kits |
| EP2095818A1 (en) * | 2008-02-29 | 2009-09-02 | AEterna Zentaris GmbH | Use of LHRH antagonists at non-castrating doses |
| KR20140091652A (ko) * | 2010-12-06 | 2014-07-22 | 아스트론 리서치 리미티드 | 안정적이며 바로 사용 가능한 세트로레릭스 주사액 |
Family Cites Families (38)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AT81285B (de) | 1914-07-30 | 1920-09-10 | I Gio Ansaldo & C S A I Gio Ah | Verfahren zur thermischen Vorbehandlung von Stahl.Verfahren zur thermischen Vorbehandlung von Stahl. |
| GB1204580A (en) * | 1968-10-05 | 1970-09-09 | Aspro Nicholas Ltd | Pharmaceutical dosage forms |
| US3733407A (en) | 1971-08-25 | 1973-05-15 | Syntex Corp | Menopause treatment |
| DE2335265A1 (de) * | 1973-07-09 | 1975-01-30 | Schering Ag | Methode zur kontrazeption durch verabfolgung von stufenkombinationspraeparaten |
| US3969502A (en) | 1972-04-14 | 1976-07-13 | Schering Aktiengesellschaft | Method for contraception by the administration of sequential contraceptive preparations |
| IE45770B1 (en) * | 1976-10-06 | 1982-11-17 | Wyeth John & Brother Ltd | Pharmaceutical dosage forms |
| DE2729068A1 (de) * | 1977-06-28 | 1979-01-11 | Rainer Dr Med Liedtke | Verfahren zur freisetzungssteuerung von arzneimitteln aus kapseln |
| CA1097233A (en) * | 1977-07-20 | 1981-03-10 | George K. E. Gregory | Packages |
| FR2403078A1 (fr) * | 1977-09-19 | 1979-04-13 | Lafon Labor | Nouveau procede de preparation de formes pharmaceutiques, cosmetiques ou de diagnostic |
| EP0002495B1 (de) * | 1977-12-14 | 1984-02-15 | Asta-Werke Aktiengesellschaft Chemische Fabrik | Erzeugnisse zur Anwendung in der cytostatischen Therapie |
| JPS5548064A (en) * | 1978-03-03 | 1980-04-05 | Yamanouchi Pharma Co Ltd | Pressureereducing sealing vessel into which agent in protein is sealed |
| DE2834226A1 (de) * | 1978-08-04 | 1980-02-28 | Merck Patent Gmbh | Presskoerper und verfahren sowie vorrichtung zu ihrer herstellung |
| JPS57166164A (en) * | 1981-04-03 | 1982-10-13 | Fujisawa Pharmaceutical Co | Case for enclosing ampoule |
| US4415085A (en) * | 1981-12-21 | 1983-11-15 | Eli Lilly And Company | Dry pharmaceutical system |
| DK90883A (da) * | 1982-03-18 | 1983-09-19 | Merck & Co Inc | Beholder til osmotisk afgivelse af et stof eller en stofblanding |
| US4564363A (en) * | 1983-07-13 | 1986-01-14 | Smithkline Beckman Corporation | Delayed action assembly |
| US4569927A (en) * | 1984-02-23 | 1986-02-11 | The Salk Institute For Biological Studies | GnRH Antagonists IV |
| US5064813A (en) * | 1984-08-02 | 1991-11-12 | Fernand Labrie | Combination therapy for selected sex steroid dependent cancers |
| GB8518828D0 (en) * | 1985-07-25 | 1985-08-29 | American Home Prod | Tablet package |
| US4817819A (en) * | 1985-12-19 | 1989-04-04 | Berlex Laboratories, Inc. | Container for tablets |
| US4662880A (en) * | 1986-03-14 | 1987-05-05 | Alza Corporation | Pseudoephedrine, brompheniramine therapy |
| EP0268066A3 (en) * | 1986-10-17 | 1990-07-11 | Syntex (U.S.A.) Inc. | Fertility control and uterine therapy in dogs with luteinizing hormone releasing hormone antagonists |
| JPS63162619A (ja) * | 1986-12-25 | 1988-07-06 | Teisan Seiyaku Kk | 遅溶性顆粒及びそれを用いた持続性複合顆粒 |
| WO1988004922A1 (fr) * | 1986-12-25 | 1988-07-14 | Teysan Pharmaceuticals Co., Ltd. | Granule a dissolution lente et granule composite a effet persistant prepare a partir du premier granule |
| US5116818A (en) * | 1987-03-10 | 1992-05-26 | Medical College Of Hampton Roads | Method and kit for contraception with GnRH-antagonist |
| US5028430A (en) * | 1987-05-08 | 1991-07-02 | Syntex (U.S.A.) Inc. | Delivery systems for the controlled administration of LHRH analogs |
| GB2206046B (en) * | 1987-06-25 | 1991-04-03 | Alza Corp | Multi-unit delivery system |
| US4800191A (en) * | 1987-07-17 | 1989-01-24 | Schally Andrew Victor | LHRH antagonists |
| JPH07552B2 (ja) * | 1987-11-06 | 1995-01-11 | 田辺製薬株式会社 | 持効性製剤 |
| IL88083A (en) * | 1987-11-06 | 1992-11-15 | Tanabe Seiyaku Co | Controlled release pharmaceutical dosage form and its preparation |
| SU1554911A1 (ru) * | 1988-05-17 | 1990-04-07 | Ленинградское Научно-Производственное Объединение Технологического Оборудования Для Производства Готовых Лекарственных Средств "Прогресс" | Пенал дл гранулированных лекарств |
| US5036047A (en) * | 1988-09-29 | 1991-07-30 | Pitman-Moore, Inc. | Method and composition for preventing conception |
| US5171835A (en) * | 1988-10-21 | 1992-12-15 | The Administrators Of The Tulane Educational Fund | LHRH antagonists |
| DK0463061T3 (da) * | 1989-03-17 | 1993-07-12 | Pitman Moore Inc | Controlled-release tilførselsindretning til afgivelse af makromolekylære proteiner |
| JP2653255B2 (ja) * | 1990-02-13 | 1997-09-17 | 武田薬品工業株式会社 | 長期徐放型マイクロカプセル |
| US5046618A (en) * | 1990-11-19 | 1991-09-10 | R. P. Scherer Corporation | Child-resistant blister pack |
| EP0569096A1 (en) * | 1992-05-08 | 1993-11-10 | Akzo Nobel N.V. | Depot preparation |
| TW333456B (en) * | 1992-12-07 | 1998-06-11 | Takeda Pharm Ind Co Ltd | A pharmaceutical composition of sustained-release preparation the invention relates to a pharmaceutical composition of sustained-release preparation which comprises a physiologically active peptide. |
-
1993
- 1993-12-09 DE DE4342091A patent/DE4342091A1/de not_active Ceased
-
1994
- 1994-11-24 AT AT94118466T patent/ATE190495T1/de active
- 1994-11-24 DE DE59409205T patent/DE59409205D1/de not_active Expired - Lifetime
- 1994-11-24 PT PT94118466T patent/PT657170E/pt unknown
- 1994-11-24 DK DK94118466T patent/DK0657170T3/da active
- 1994-11-24 EP EP94118466A patent/EP0657170B1/de not_active Expired - Lifetime
- 1994-11-24 ES ES94118466T patent/ES2145803T3/es not_active Expired - Lifetime
- 1994-12-08 CA CA002137595A patent/CA2137595C/en not_active Expired - Lifetime
- 1994-12-08 US US08/354,838 patent/US5663145A/en not_active Expired - Lifetime
- 1994-12-09 JP JP30647594A patent/JP3439855B2/ja not_active Expired - Lifetime
-
2000
- 2000-04-26 GR GR20000401003T patent/GR3033319T3/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| PT657170E (pt) | 2000-07-31 |
| DE4342091A1 (de) | 1995-06-14 |
| JPH07194670A (ja) | 1995-08-01 |
| EP0657170A1 (de) | 1995-06-14 |
| EP0657170B1 (de) | 2000-03-15 |
| GR3033319T3 (en) | 2000-09-29 |
| CA2137595A1 (en) | 1995-06-10 |
| US5663145A (en) | 1997-09-02 |
| JP3439855B2 (ja) | 2003-08-25 |
| ES2145803T3 (es) | 2000-07-16 |
| ATE190495T1 (de) | 2000-04-15 |
| DE59409205D1 (de) | 2000-04-20 |
| CA2137595C (en) | 2005-05-31 |
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