DK0669934T3 - Fremgangsmåde til fremstilling af krystaller af væksthormon og derved opnåede krystaller - Google Patents

Fremgangsmåde til fremstilling af krystaller af væksthormon og derved opnåede krystaller

Info

Publication number: DK0669934T3
Authority: DK; Denmark
Prior art keywords: crystals; pct; growth hormone; date; alkyl
Prior art date: 1992-10-28

Application number

DK93924266T

Other languages

English (en)

Inventor

Ebba Florin-Robertsson

Elvy Hikby

Ronny Lundin

Sirkka Thome

Gertrud Westin-Sjidahl

Tomas Lundqvist

Original Assignee

Pharmacia & Upjohn Ab

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1992-10-28

Filing date

1993-10-27

Publication date

1999-08-23

1992-10-28 Priority claimed from SE9203175A external-priority patent/SE9203175D0/xx

1993-10-27 Application filed by Pharmacia & Upjohn Ab filed Critical Pharmacia & Upjohn Ab

1999-08-23 Application granted granted Critical

1999-08-23 Publication of DK0669934T3 publication Critical patent/DK0669934T3/da

Links

239000013078 crystal Substances 0.000 title abstract 5
102000018997 Growth Hormone Human genes 0.000 title abstract 4
108010051696 Growth Hormone Proteins 0.000 title abstract 4
239000000122 growth hormone Substances 0.000 title abstract 4
238000000034 method Methods 0.000 title abstract 2
125000001624 naphthyl group Chemical class 0.000 abstract 2
125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 2
125000000217 alkyl group Chemical group 0.000 abstract 1
239000007864 aqueous solution Substances 0.000 abstract 1
150000001875 compounds Chemical class 0.000 abstract 1
238000004519 manufacturing process Methods 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/61—Growth hormone [GH], i.e. somatotropin
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/06—Drugs for disorders of the endocrine system of the anterior pituitary hormones, e.g. TSH, ACTH, FSH, LH, PRL, GH
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Endocrinology (AREA)
Organic Chemistry (AREA)
Medicinal Chemistry (AREA)
General Health & Medical Sciences (AREA)
Biophysics (AREA)
Molecular Biology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Genetics & Genomics (AREA)
Biochemistry (AREA)
Gastroenterology & Hepatology (AREA)
Zoology (AREA)
Toxicology (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Bioinformatics & Cheminformatics (AREA)
Animal Behavior & Ethology (AREA)
Diabetes (AREA)
Pharmacology & Pharmacy (AREA)
Veterinary Medicine (AREA)
Engineering & Computer Science (AREA)
Public Health (AREA)
Chemical Kinetics & Catalysis (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Peptides Or Proteins (AREA)
Steroid Compounds (AREA)
Crystals, And After-Treatments Of Crystals (AREA)
Medicinal Preparation (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)

DK93924266T 1992-10-28 1993-10-27 Fremgangsmåde til fremstilling af krystaller af væksthormon og derved opnåede krystaller DK0669934T3 (da)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
SE9203175A SE9203175D0 (sv)	1992-10-28	1992-10-28	Growth hormone
SE19939302278A SE9302278D0 (sv)	1992-10-28	1993-07-02	Growth hormone
PCT/SE1993/000885 WO1994010192A1 (en)	1992-10-28	1993-10-27	Process for manufacturing crystals of growth hormone and crystals thereby obtained

Publications (1)

Publication Number	Publication Date
DK0669934T3 true DK0669934T3 (da)	1999-08-23

Family

ID=26661557

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK93924266T DK0669934T3 (da)	1992-10-28	1993-10-27	Fremgangsmåde til fremstilling af krystaller af væksthormon og derved opnåede krystaller

Country Status (13)

Country	Link
US (1)	US5734026A (da)
EP (1)	EP0669934B1 (da)
JP (1)	JP3470135B2 (da)
AT (1)	ATE174602T1 (da)
AU (1)	AU679012B2 (da)
CA (1)	CA2147482C (da)
DE (1)	DE69322654T2 (da)
DK (1)	DK0669934T3 (da)
ES (1)	ES2126660T3 (da)
FI (1)	FI110609B (da)
NO (1)	NO320171B1 (da)
SE (1)	SE9302278D0 (da)
WO (1)	WO1994010192A1 (da)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
SE9302278D0 (sv) *	1992-10-28	1993-07-02	Kabi Pharmacia Ab	Growth hormone
US6500933B1 (en)	1997-09-05	2002-12-31	Altus Biologics Inc.	Methods of preparing carbohydrate crosslinked glycoprotein crystals
DK1009759T3 (da) *	1997-09-05	2008-08-04	Altus Pharmaceuticals Inc	Carbohydrat-tværbundne glycoproteinkrystaller
US6380357B2 (en)	1997-12-16	2002-04-30	Eli Lilly And Company	Glucagon-like peptide-1 crystals
US6541606B2 (en) *	1997-12-31	2003-04-01	Altus Biologics Inc.	Stabilized protein crystals formulations containing them and methods of making them
AU2003208945B2 (en) *	2002-02-20	2008-05-01	Emisphere Technologies, Inc	Method for administering GLP-1 molecules
SE0202719D0 (sv) *	2002-09-13	2002-09-13	Pharmacia Ab	Process for mfg crystals of growth hormone
DK1581251T3 (da)	2002-12-31	2016-06-27	Althea Tech Inc	Krystaller af humant væksthormon og fremgangsmåder til fremstilling deraf
US20060286129A1 (en) *	2003-12-19	2006-12-21	Emisphere Technologies, Inc.	Oral GLP-1 formulations
US7799273B2 (en)	2004-05-06	2010-09-21	Smp Logic Systems Llc	Manufacturing execution system for validation, quality and risk assessment and monitoring of pharmaceutical manufacturing processes
US7444197B2 (en)	2004-05-06	2008-10-28	Smp Logic Systems Llc	Methods, systems, and software program for validation and monitoring of pharmaceutical manufacturing processes
EP1976551A4 (en) *	2005-12-23	2009-12-30	Altus Pharmaceuticals Inc	COMPOSITIONS COMPRISING COMPLEX PROTEIN CRYSTALS BY POLYCATIONS AND PROCESSING METHOD THEREOF

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
MY107450A (en) *	1990-06-04	1995-12-30	Schering Corp	Method for preparing interferon alpha-2 crystals.
IL98484A0 (en) *	1990-06-15	1992-07-15	Schering Corp	Crystalline interleukin-4
DK168790D0 (da) *	1990-07-13	1990-07-13	Novo Nordisk As
US5015627A (en) *	1990-07-20	1991-05-14	Smithkline Beecham Corporation	Stabilized somatotropin for parenteral administration
SE9302278D0 (sv) *	1992-10-28	1993-07-02	Kabi Pharmacia Ab	Growth hormone

1993
- 1993-07-02 SE SE19939302278A patent/SE9302278D0/xx unknown
- 1993-10-27 AT AT93924266T patent/ATE174602T1/de not_active IP Right Cessation
- 1993-10-27 EP EP93924266A patent/EP0669934B1/en not_active Expired - Lifetime
- 1993-10-27 ES ES93924266T patent/ES2126660T3/es not_active Expired - Lifetime
- 1993-10-27 WO PCT/SE1993/000885 patent/WO1994010192A1/en not_active Ceased
- 1993-10-27 DK DK93924266T patent/DK0669934T3/da active
- 1993-10-27 AU AU54011/94A patent/AU679012B2/en not_active Ceased
- 1993-10-27 JP JP51096494A patent/JP3470135B2/ja not_active Expired - Fee Related
- 1993-10-27 CA CA002147482A patent/CA2147482C/en not_active Expired - Fee Related
- 1993-10-27 DE DE69322654T patent/DE69322654T2/de not_active Expired - Fee Related
- 1993-10-27 US US08/424,450 patent/US5734026A/en not_active Expired - Fee Related
1995
- 1995-04-24 NO NO19951547A patent/NO320171B1/no unknown
- 1995-04-27 FI FI952021A patent/FI110609B/fi active

Also Published As

Publication number	Publication date
JP3470135B2 (ja)	2003-11-25
FI952021A0 (fi)	1995-04-27
NO320171B1 (no)	2005-11-07
AU5401194A (en)	1994-05-24
HK1013299A1 (en)	1999-08-20
CA2147482C (en)	2003-09-23
FI110609B (fi)	2003-02-28
WO1994010192A1 (en)	1994-05-11
ATE174602T1 (de)	1999-01-15
EP0669934A1 (en)	1995-09-06
DE69322654D1 (de)	1999-01-28
EP0669934B1 (en)	1998-12-16
CA2147482A1 (en)	1994-05-11
ES2126660T3 (es)	1999-04-01
NO951547D0 (no)	1995-04-24
NO951547L (no)	1995-04-24
JPH08505127A (ja)	1996-06-04
DE69322654T2 (de)	1999-06-17
FI952021L (fi)	1995-04-27
AU679012B2 (en)	1997-06-19
US5734026A (en)	1998-03-31
SE9302278D0 (sv)	1993-07-02

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