DK0669934T3 - Fremgangsmåde til fremstilling af krystaller af væksthormon og derved opnåede krystaller - Google Patents

Fremgangsmåde til fremstilling af krystaller af væksthormon og derved opnåede krystaller

Info

Publication number
DK0669934T3
DK0669934T3 DK93924266T DK93924266T DK0669934T3 DK 0669934 T3 DK0669934 T3 DK 0669934T3 DK 93924266 T DK93924266 T DK 93924266T DK 93924266 T DK93924266 T DK 93924266T DK 0669934 T3 DK0669934 T3 DK 0669934T3
Authority
DK
Denmark
Prior art keywords
crystals
pct
growth hormone
date
alkyl
Prior art date
Application number
DK93924266T
Other languages
English (en)
Inventor
Ebba Florin-Robertsson
Elvy Hikby
Ronny Lundin
Sirkka Thome
Gertrud Westin-Sjidahl
Tomas Lundqvist
Original Assignee
Pharmacia & Upjohn Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from SE9203175A external-priority patent/SE9203175D0/xx
Application filed by Pharmacia & Upjohn Ab filed Critical Pharmacia & Upjohn Ab
Application granted granted Critical
Publication of DK0669934T3 publication Critical patent/DK0669934T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/61—Growth hormone [GH], i.e. somatotropin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/06—Drugs for disorders of the endocrine system of the anterior pituitary hormones, e.g. TSH, ACTH, FSH, LH, PRL, GH
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Endocrinology (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Diabetes (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Steroid Compounds (AREA)
  • Crystals, And After-Treatments Of Crystals (AREA)
  • Medicinal Preparation (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
DK93924266T 1992-10-28 1993-10-27 Fremgangsmåde til fremstilling af krystaller af væksthormon og derved opnåede krystaller DK0669934T3 (da)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
SE9203175A SE9203175D0 (sv) 1992-10-28 1992-10-28 Growth hormone
SE19939302278A SE9302278D0 (sv) 1992-10-28 1993-07-02 Growth hormone
PCT/SE1993/000885 WO1994010192A1 (en) 1992-10-28 1993-10-27 Process for manufacturing crystals of growth hormone and crystals thereby obtained

Publications (1)

Publication Number Publication Date
DK0669934T3 true DK0669934T3 (da) 1999-08-23

Family

ID=26661557

Family Applications (1)

Application Number Title Priority Date Filing Date
DK93924266T DK0669934T3 (da) 1992-10-28 1993-10-27 Fremgangsmåde til fremstilling af krystaller af væksthormon og derved opnåede krystaller

Country Status (13)

Country Link
US (1) US5734026A (da)
EP (1) EP0669934B1 (da)
JP (1) JP3470135B2 (da)
AT (1) ATE174602T1 (da)
AU (1) AU679012B2 (da)
CA (1) CA2147482C (da)
DE (1) DE69322654T2 (da)
DK (1) DK0669934T3 (da)
ES (1) ES2126660T3 (da)
FI (1) FI110609B (da)
NO (1) NO320171B1 (da)
SE (1) SE9302278D0 (da)
WO (1) WO1994010192A1 (da)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE9302278D0 (sv) * 1992-10-28 1993-07-02 Kabi Pharmacia Ab Growth hormone
AU8772498A (en) * 1997-09-05 1999-03-29 Altus Biologics Inc. Carbohydrate crosslinked glycoprotein crystals
US6500933B1 (en) 1997-09-05 2002-12-31 Altus Biologics Inc. Methods of preparing carbohydrate crosslinked glycoprotein crystals
US6380357B2 (en) * 1997-12-16 2002-04-30 Eli Lilly And Company Glucagon-like peptide-1 crystals
US6541606B2 (en) * 1997-12-31 2003-04-01 Altus Biologics Inc. Stabilized protein crystals formulations containing them and methods of making them
CN1332711C (zh) * 2002-02-20 2007-08-22 埃米球科技有限公司 施用glp－1分子的方法
SE0202719D0 (sv) * 2002-09-13 2002-09-13 Pharmacia Ab Process for mfg crystals of growth hormone
EP2460530A3 (en) 2002-12-31 2012-08-29 Althea Technologies, Inc. Human growth hormone crystals and methods for preparing them
US20060286129A1 (en) * 2003-12-19 2006-12-21 Emisphere Technologies, Inc. Oral GLP-1 formulations
US7799273B2 (en) * 2004-05-06 2010-09-21 Smp Logic Systems Llc Manufacturing execution system for validation, quality and risk assessment and monitoring of pharmaceutical manufacturing processes
US7444197B2 (en) 2004-05-06 2008-10-28 Smp Logic Systems Llc Methods, systems, and software program for validation and monitoring of pharmaceutical manufacturing processes
US20090023629A1 (en) * 2005-12-23 2009-01-22 Altus Pharmaceuticals Inc. Compositions comprising polycation-complexed protein crystals and methods of treatment using them

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1991018927A1 (en) * 1990-06-04 1991-12-12 Schering Corporation Method for preparing interferon alpha-2 crystals
HU209313B (en) * 1990-06-15 1994-04-28 Schering Corp Process for producing crystalline interleukin-4 and pharmaceutical compositions comprising same
DK168790D0 (da) * 1990-07-13 1990-07-13 Novo Nordisk As
US5015627A (en) * 1990-07-20 1991-05-14 Smithkline Beecham Corporation Stabilized somatotropin for parenteral administration
SE9302278D0 (sv) * 1992-10-28 1993-07-02 Kabi Pharmacia Ab Growth hormone

Also Published As

Publication number Publication date
US5734026A (en) 1998-03-31
ES2126660T3 (es) 1999-04-01
AU5401194A (en) 1994-05-24
NO951547L (no) 1995-04-24
FI110609B (fi) 2003-02-28
JP3470135B2 (ja) 2003-11-25
DE69322654T2 (de) 1999-06-17
FI952021L (fi) 1995-04-27
AU679012B2 (en) 1997-06-19
HK1013299A1 (en) 1999-08-20
ATE174602T1 (de) 1999-01-15
NO320171B1 (no) 2005-11-07
DE69322654D1 (de) 1999-01-28
SE9302278D0 (sv) 1993-07-02
WO1994010192A1 (en) 1994-05-11
NO951547D0 (no) 1995-04-24
CA2147482C (en) 2003-09-23
JPH08505127A (ja) 1996-06-04
EP0669934B1 (en) 1998-12-16
EP0669934A1 (en) 1995-09-06
FI952021A0 (fi) 1995-04-27
CA2147482A1 (en) 1994-05-11

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