ES8604231A1 - Un procedimiento para preparar un compuesto antibiotico de la clase de vancomicina - Google Patents

Un procedimiento para preparar un compuesto antibiotico de la clase de vancomicina

Info

Publication number
ES8604231A1
ES8604231A1 ES545185A ES545185A ES8604231A1 ES 8604231 A1 ES8604231 A1 ES 8604231A1 ES 545185 A ES545185 A ES 545185A ES 545185 A ES545185 A ES 545185A ES 8604231 A1 ES8604231 A1 ES 8604231A1
Authority
ES
Spain
Prior art keywords
aad
antibiotic
procedure
class
vancomicin
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES545185A
Other languages
English (en)
Other versions
ES545185A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pfizer Inc
Original Assignee
SmithKline Beecham Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by SmithKline Beecham Corp filed Critical SmithKline Beecham Corp
Publication of ES545185A0 publication Critical patent/ES545185A0/es
Publication of ES8604231A1 publication Critical patent/ES8604231A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K9/00—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof
    • C07K9/006—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof the peptide sequence being part of a ring structure
    • C07K9/008—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof the peptide sequence being part of a ring structure directly attached to a hetero atom of the saccharide radical, e.g. actaplanin, avoparcin, ristomycin, vancomycin
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K20/00—Accessory food factors for animal feeding-stuffs
    • A23K20/10—Organic substances
    • A23K20/195—Antibiotics
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K50/00—Feeding-stuffs specially adapted for particular animals
    • A23K50/30—Feeding-stuffs specially adapted for particular animals for swines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Polymers & Plastics (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Food Science & Technology (AREA)
  • Zoology (AREA)
  • Animal Husbandry (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Birds (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Diabetes (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Fodder In General (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

PROCEDIMIENTO PARA PREPARAR UN COMPUESTO ANTIBIOTICO DE LA CLASE DE VANCOMICINA. COMPRENDE: A) HIDROLIZAR A LOS FACTORES ANTIBIOTICOS PRINCIPALES (AAD 216A), (AAD 216B) Y (AAD 216C) DEL COMPLEJO ANTIBIOTICO (AAD 216) CON ACIDO CLORHIDRICO AL CINCO POR CIENTO EN DIMENTILSULFOXIDO, A UNA TEMPERATURA DE 100JC Y DURANTE 15 MINUTOS; Y B) AISLAR EL AGLICON (AAD 216) Y PSEUDOAGLICON (AAD 216A) POR CROMATOGRAFIA, PARA OBTENER UN COMPUESTO DE FORMULA (I). SIENDO: R1 HIDROGENO O MANOSILO Y R2 HIDROGENO O UN RADICAL DE GLICOLIPIDO DERIVADO DEL ANTIBIOTICO (AAD 216). SE UTILIZAN PARA EL CRECIMIENTO Y EL TRATAMIENTO DE LA MASTITIS BOVINA.
ES545185A 1983-07-13 1985-07-15 Un procedimiento para preparar un compuesto antibiotico de la clase de vancomicina Expired ES8604231A1 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US51351483A 1983-07-13 1983-07-13
US06/611,070 US4521335A (en) 1983-07-13 1984-05-17 Aglycone and pseudo-aglycones of the AAD 216 antibiotics

Publications (2)

Publication Number Publication Date
ES545185A0 ES545185A0 (es) 1986-01-16
ES8604231A1 true ES8604231A1 (es) 1986-01-16

Family

ID=27057900

Family Applications (2)

Application Number Title Priority Date Filing Date
ES84534249A Granted ES534249A0 (es) 1983-07-13 1984-07-12 Un procedimiento para preparar un compuesto antibiotico
ES545185A Expired ES8604231A1 (es) 1983-07-13 1985-07-15 Un procedimiento para preparar un compuesto antibiotico de la clase de vancomicina

Family Applications Before (1)

Application Number Title Priority Date Filing Date
ES84534249A Granted ES534249A0 (es) 1983-07-13 1984-07-12 Un procedimiento para preparar un compuesto antibiotico

Country Status (11)

Country Link
US (1) US4521335A (es)
EP (1) EP0132116B1 (es)
JP (1) JP2551550B2 (es)
AU (1) AU565151B2 (es)
CA (1) CA1238316A (es)
DE (1) DE3481307D1 (es)
DK (1) DK162772C (es)
ES (2) ES534249A0 (es)
GR (1) GR81499B (es)
HK (1) HK50093A (es)
IE (1) IE57869B1 (es)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8307847D0 (en) * 1983-03-22 1983-04-27 Lepetit Spa Antibiotics l 17054 and l 17046
US4548974A (en) * 1983-07-13 1985-10-22 Smithkline Beckman Corporation Antibiotics produced by Kibdelosporangium aridum shearer
AU579120B2 (en) * 1983-12-16 1988-11-17 Gruppo Lepetit S.P.A. Chemical process for preparing antibiotic L 17392 (deglucoteicoplanin) and its salts
GB8333624D0 (en) * 1983-12-16 1984-01-25 Lepetit Spa Antibiotics l 17054 and l 17392
IT1173329B (it) * 1984-02-21 1987-06-24 Lepetit Spa Procedimento per la trasformazione quantitativa di teicoplanina a2 fattore 1 in teicoplanina a2 fattore 3
GB8415092D0 (en) * 1984-06-13 1984-07-18 Lepetit Spa Ester derivatives
GB8415093D0 (en) * 1984-06-13 1984-07-18 Lepetit Spa Antibiotic l 17392
EP0211490B1 (en) 1985-06-20 1992-02-26 Smithkline Beecham Corporation Antibiotics of the vancomycin-class
US4694069A (en) * 1985-09-30 1987-09-15 Smithkline Beckman Corporation Kibdelosporangium aridum SK&F-AAD-609
GB8531846D0 (en) * 1985-12-30 1986-02-05 Lepetit Spa Antibiotic a 40926 mannosyl aglycon
GB8608809D0 (en) * 1986-04-11 1986-05-14 Lepetit Spa Antibiotic
DK363587A (da) * 1986-07-30 1988-01-31 Smithkline Beckman Corp Antibiotika og fremstilling heraf under anvendelseaf actinomadura parvosata
EP0273727A3 (en) * 1986-12-30 1990-01-17 Smithkline Beecham Corporation Glycosylated glycopeptides
GB8701872D0 (en) * 1987-01-28 1987-03-04 Lepetit Spa N15-alkyl & n15,n15-dialkyl derivatives
US4882313A (en) * 1987-07-31 1989-11-21 Smithkline Beckman Corporation Carboxamide derivatives of glycopeptides
ES2084595T3 (es) * 1988-12-27 1996-05-16 Lepetit Spa Procedimiento quimico mejorado para preparar el antibiotico l/17392 (desglucoteicoplanina) y sus sales.
AU701463B2 (en) * 1995-07-05 1999-01-28 Sanofi Aventis S.P.A. Purification of dalbaheptide antibiotics by isoelectric focusing
WO1997038706A1 (en) * 1996-04-12 1997-10-23 Eli Lilly And Company Glycopeptide compounds
US6037447A (en) * 1996-04-12 2000-03-14 Eli Lilly And Company Glycopeptide compounds

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4322343A (en) * 1980-12-18 1982-03-30 Eli Lilly And Company Pseudo-aglycone of actaplanin
FI75190C (fi) * 1982-03-24 1988-05-09 Lilly Co Eli Foerfarande foer framstaellning av ett antibiotikum a41030-komplex eller dess faktorer a, b, c, d, e, f och g.
US4456593A (en) * 1982-06-22 1984-06-26 Abbott Laboratories Ristocetin ψ-aglycone as an antibacterial agent

Also Published As

Publication number Publication date
ES545185A0 (es) 1986-01-16
JP2551550B2 (ja) 1996-11-06
EP0132116B1 (en) 1990-02-07
CA1238316A (en) 1988-06-21
DK340884D0 (da) 1984-07-11
GR81499B (es) 1984-12-11
EP0132116A2 (en) 1985-01-23
DK340884A (da) 1985-01-14
HK50093A (en) 1993-05-27
JPS6069097A (ja) 1985-04-19
IE57869B1 (en) 1993-05-05
IE841761L (en) 1985-01-13
EP0132116A3 (en) 1986-12-10
DK162772C (da) 1992-04-27
AU565151B2 (en) 1987-09-03
US4521335A (en) 1985-06-04
DE3481307D1 (de) 1990-03-15
DK162772B (da) 1991-12-09
ES8602841A1 (es) 1985-12-01
AU3041084A (en) 1985-01-17
ES534249A0 (es) 1985-12-01

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Legal Events

Date Code Title Description
PC2A Transfer of patent

Owner name: PFIZER INC.

FD1A Patent lapsed

Effective date: 20051026