ES8604231A1 - Un procedimiento para preparar un compuesto antibiotico de la clase de vancomicina - Google Patents

Un procedimiento para preparar un compuesto antibiotico de la clase de vancomicina

Info

Publication number
ES8604231A1
ES8604231A1 ES545185A ES545185A ES8604231A1 ES 8604231 A1 ES8604231 A1 ES 8604231A1 ES 545185 A ES545185 A ES 545185A ES 545185 A ES545185 A ES 545185A ES 8604231 A1 ES8604231 A1 ES 8604231A1
Authority
ES
Spain
Prior art keywords
aad
antibiotic
procedure
class
vancomicin
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES545185A
Other languages
English (en)
Other versions
ES545185A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pfizer Inc
Original Assignee
SmithKline Beecham Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by SmithKline Beecham Corp filed Critical SmithKline Beecham Corp
Publication of ES8604231A1 publication Critical patent/ES8604231A1/es
Publication of ES545185A0 publication Critical patent/ES545185A0/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K9/00—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof
    • C07K9/006—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof the peptide sequence being part of a ring structure
    • C07K9/008—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof the peptide sequence being part of a ring structure directly attached to a hetero atom of the saccharide radical, e.g. actaplanin, avoparcin, ristomycin, vancomycin
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K20/00—Accessory food factors for animal feeding-stuffs
    • A23K20/10—Organic substances
    • A23K20/195—Antibiotics
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K50/00—Feeding-stuffs specially adapted for particular animals
    • A23K50/30—Feeding-stuffs specially adapted for particular animals for swines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Polymers & Plastics (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Food Science & Technology (AREA)
  • Zoology (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Husbandry (AREA)
  • Genetics & Genomics (AREA)
  • Birds (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biophysics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biochemistry (AREA)
  • Hematology (AREA)
  • Oncology (AREA)
  • Obesity (AREA)
  • Communicable Diseases (AREA)
  • Diabetes (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)
  • Fodder In General (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)

Abstract

PROCEDIMIENTO PARA PREPARAR UN COMPUESTO ANTIBIOTICO DE LA CLASE DE VANCOMICINA. COMPRENDE: A) HIDROLIZAR A LOS FACTORES ANTIBIOTICOS PRINCIPALES (AAD 216A), (AAD 216B) Y (AAD 216C) DEL COMPLEJO ANTIBIOTICO (AAD 216) CON ACIDO CLORHIDRICO AL CINCO POR CIENTO EN DIMENTILSULFOXIDO, A UNA TEMPERATURA DE 100JC Y DURANTE 15 MINUTOS; Y B) AISLAR EL AGLICON (AAD 216) Y PSEUDOAGLICON (AAD 216A) POR CROMATOGRAFIA, PARA OBTENER UN COMPUESTO DE FORMULA (I). SIENDO: R1 HIDROGENO O MANOSILO Y R2 HIDROGENO O UN RADICAL DE GLICOLIPIDO DERIVADO DEL ANTIBIOTICO (AAD 216). SE UTILIZAN PARA EL CRECIMIENTO Y EL TRATAMIENTO DE LA MASTITIS BOVINA.
ES545185A 1983-07-13 1985-07-15 Un procedimiento para preparar un compuesto antibiotico de la clase de vancomicina Expired ES8604231A1 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US51351483A 1983-07-13 1983-07-13
US06/611,070 US4521335A (en) 1983-07-13 1984-05-17 Aglycone and pseudo-aglycones of the AAD 216 antibiotics

Publications (2)

Publication Number Publication Date
ES8604231A1 true ES8604231A1 (es) 1986-01-16
ES545185A0 ES545185A0 (es) 1986-01-16

Family

ID=27057900

Family Applications (2)

Application Number Title Priority Date Filing Date
ES84534249A Granted ES534249A0 (es) 1983-07-13 1984-07-12 Un procedimiento para preparar un compuesto antibiotico
ES545185A Expired ES8604231A1 (es) 1983-07-13 1985-07-15 Un procedimiento para preparar un compuesto antibiotico de la clase de vancomicina

Family Applications Before (1)

Application Number Title Priority Date Filing Date
ES84534249A Granted ES534249A0 (es) 1983-07-13 1984-07-12 Un procedimiento para preparar un compuesto antibiotico

Country Status (11)

Country Link
US (1) US4521335A (es)
EP (1) EP0132116B1 (es)
JP (1) JP2551550B2 (es)
AU (1) AU565151B2 (es)
CA (1) CA1238316A (es)
DE (1) DE3481307D1 (es)
DK (1) DK162772C (es)
ES (2) ES534249A0 (es)
GR (1) GR81499B (es)
HK (1) HK50093A (es)
IE (1) IE57869B1 (es)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8307847D0 (en) * 1983-03-22 1983-04-27 Lepetit Spa Antibiotics l 17054 and l 17046
US4548974A (en) * 1983-07-13 1985-10-22 Smithkline Beckman Corporation Antibiotics produced by Kibdelosporangium aridum shearer
AU579120B2 (en) * 1983-12-16 1988-11-17 Gruppo Lepetit S.P.A. Chemical process for preparing antibiotic L 17392 (deglucoteicoplanin) and its salts
GB8333624D0 (en) * 1983-12-16 1984-01-25 Lepetit Spa Antibiotics l 17054 and l 17392
IT1173329B (it) * 1984-02-21 1987-06-24 Lepetit Spa Procedimento per la trasformazione quantitativa di teicoplanina a2 fattore 1 in teicoplanina a2 fattore 3
GB8415093D0 (en) * 1984-06-13 1984-07-18 Lepetit Spa Antibiotic l 17392
GB8415092D0 (en) * 1984-06-13 1984-07-18 Lepetit Spa Ester derivatives
EP0211490B1 (en) * 1985-06-20 1992-02-26 Smithkline Beecham Corporation Antibiotics of the vancomycin-class
US4694069A (en) * 1985-09-30 1987-09-15 Smithkline Beckman Corporation Kibdelosporangium aridum SK&F-AAD-609
GB8531846D0 (en) * 1985-12-30 1986-02-05 Lepetit Spa Antibiotic a 40926 mannosyl aglycon
GB8608809D0 (en) * 1986-04-11 1986-05-14 Lepetit Spa Antibiotic
DK363587A (da) * 1986-07-30 1988-01-31 Smithkline Beckman Corp Antibiotika og fremstilling heraf under anvendelseaf actinomadura parvosata
PT86457B (pt) * 1986-12-30 1990-11-20 Smithkline Beecham Corp Processo para a preparacao de glicopeptidos glicosilados e de composicoes que os contem
GB8701872D0 (en) * 1987-01-28 1987-03-04 Lepetit Spa N15-alkyl & n15,n15-dialkyl derivatives
US4882313A (en) * 1987-07-31 1989-11-21 Smithkline Beckman Corporation Carboxamide derivatives of glycopeptides
ATE135369T1 (de) * 1988-12-27 1996-03-15 Lepetit Spa Chemisches verfahren zur herstellung des antibiotikums l 17392 (deglukoteicoplanin) und dessen salze
PT836619E (pt) * 1995-07-05 2004-11-30 Aventis Bulk S P A Purificacao de antibioticos dalba-heptidicos por focagem isoelectrica
US6037447A (en) * 1996-04-12 2000-03-14 Eli Lilly And Company Glycopeptide compounds
CA2251086C (en) * 1996-04-12 2007-02-20 Eli Lilly And Company Glycopeptide compounds

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4322343A (en) * 1980-12-18 1982-03-30 Eli Lilly And Company Pseudo-aglycone of actaplanin
RO86375A (ro) * 1982-03-24 1985-03-15 Eli Lilly And Co,Us Procedeu pentru prepararea antibioticului a 41030
US4456593A (en) * 1982-06-22 1984-06-26 Abbott Laboratories Ristocetin ψ-aglycone as an antibacterial agent

Also Published As

Publication number Publication date
CA1238316A (en) 1988-06-21
DK340884D0 (da) 1984-07-11
EP0132116B1 (en) 1990-02-07
ES545185A0 (es) 1986-01-16
US4521335A (en) 1985-06-04
ES8602841A1 (es) 1985-12-01
HK50093A (en) 1993-05-27
ES534249A0 (es) 1985-12-01
DK162772B (da) 1991-12-09
EP0132116A2 (en) 1985-01-23
JP2551550B2 (ja) 1996-11-06
DE3481307D1 (de) 1990-03-15
DK340884A (da) 1985-01-14
GR81499B (es) 1984-12-11
EP0132116A3 (en) 1986-12-10
IE57869B1 (en) 1993-05-05
DK162772C (da) 1992-04-27
JPS6069097A (ja) 1985-04-19
AU3041084A (en) 1985-01-17
IE841761L (en) 1985-01-13
AU565151B2 (en) 1987-09-03

Similar Documents

Publication Publication Date Title
ES8604231A1 (es) Un procedimiento para preparar un compuesto antibiotico de la clase de vancomicina
EE03047B1 (et) Kristalliline veevaba laktitool, selle valmistamise meetod ja kasutamine
YU46699B (sh) Kristalni monohidratni oblik 1-karbacefalosporina
ES8606353A1 (es) Procedimiento para preparar nuevas pirrolidina-2,5-dionas espiro-enlazadas
ES8601925A1 (es) Procedimiento para la preparacion de derivados de pirimidina.
ES2049833T3 (es) Procedimiento para la preparacion de cristales de sulfuro sodico anhidro.
DK680387A (da) Fremgangsmaade til fremstilling af krystallinsk vandfrit cefadroxil-monohydrat
ES515545A0 (es) "un procedimiento para la purificacion o aislamiento de una amida de un dipeptido l-aspartil-d-aminoacido".
DK399787D0 (da) Polycyclisk etherforbindelse, fremgangsmaade til fremstilling deraf, foderblandinger indeholdende forbindelsen og fremgangsmaade til fremme af vaekst og/eller foderudbyttelse hos svin og kvaeg
ES8506092A1 (es) Un metodo de producir un precursor del factor de liberacion de la hormona del crecimiento humana
AR241015A2 (es) "procedimiento para preparar acidos 16-fenoxiprostatrienoicos"
EP0099168A3 (en) Apparatus for performing solution growth of group ii-vi compound semiconductor crystal
IT1206712B (it) Procedimento per la preparazione di derivati di fenil alanina.
BR8300219A (pt) Composicoes herbicidas, contendo derivados de tiadiazol, e,processo para preparacao desses derivados
AR230451A1 (es) Procedimiento para preparar derivados del acido pirido(1,3-de)1,4-benzoxacin-6-carboxilico
AR241137A2 (es) "procedimiento para preparar beta-metilen-2 o 3-tiofenetanamina".
ES2097002T3 (es) Procedimiento para convertir loracarbef dihidrato en loracarbef monohidrato.
ES511759A0 (es) Procedimiento para preparar derivados del acido 1,4-tiazan-3-carboxilico.
ES8505647A1 (es) Procedimiento para preparar un derivado de insulina
ES8308538A1 (es) Un procedimiento para la preparacion de derivados de trifluormetanosulfonanilida.
IT1164378B (it) Derivati di 28-metil-brassinosteroidi, procedimento per la preparazione di questi composti e mezzi che li contengono con effetto regolatore della crescita per piante
IT8323245A0 (it) Derivati dell'acido 2-fenossipropionico e pentiti, procedimento per preparare questi composti e mezzi con effetto erbicida che li contengono.
IT1161632B (it) Derivati di eteri benzilici di pentiti,procediemento per la preparazione di questi composti,nonche' mezzi che li contengono con effetto regolatore della crescita per piante
ES534473A0 (es) Procedimiento para la obtencion del acido 2, 2-dimetil-5(2, 5-xililoxi) valerico
ES8603169A1 (es) Procedimiento para preparar acidos y-alenil-y-aminobutiricos

Legal Events

Date Code Title Description
PC2A Transfer of patent

Owner name: PFIZER INC.

FD1A Patent lapsed

Effective date: 20051026