DK0671904T3 - Antibiotisk præparat og anvendelse mod lægemiddelresistente infektioner - Google Patents
Antibiotisk præparat og anvendelse mod lægemiddelresistente infektionerInfo
- Publication number
- DK0671904T3 DK0671904T3 DK93911272T DK93911272T DK0671904T3 DK 0671904 T3 DK0671904 T3 DK 0671904T3 DK 93911272 T DK93911272 T DK 93911272T DK 93911272 T DK93911272 T DK 93911272T DK 0671904 T3 DK0671904 T3 DK 0671904T3
- Authority
- DK
- Denmark
- Prior art keywords
- drug resistant
- use against
- against drug
- formulation
- resistant infections
- Prior art date
Links
- 229940079593 drug Drugs 0.000 title abstract 3
- 239000003814 drug Substances 0.000 title abstract 3
- 230000003115 biocidal effect Effects 0.000 title 1
- 208000015181 infectious disease Diseases 0.000 title 1
- 238000009472 formulation Methods 0.000 abstract 3
- 239000000203 mixture Substances 0.000 abstract 3
- 229940126575 aminoglycoside Drugs 0.000 abstract 2
- 150000002632 lipids Chemical class 0.000 abstract 2
- 238000000034 method Methods 0.000 abstract 2
- 241000894006 Bacteria Species 0.000 abstract 1
- 229930182558 Sterol Natural products 0.000 abstract 1
- 230000036571 hydration Effects 0.000 abstract 1
- 238000006703 hydration reaction Methods 0.000 abstract 1
- 239000002502 liposome Substances 0.000 abstract 1
- 230000007935 neutral effect Effects 0.000 abstract 1
- 150000003432 sterols Chemical class 0.000 abstract 1
- 235000003702 sterols Nutrition 0.000 abstract 1
- 230000007704 transition Effects 0.000 abstract 1
- 239000002691 unilamellar liposome Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7028—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
- A61K31/7034—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin
- A61K31/7036—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin having at least one amino group directly attached to the carbocyclic ring, e.g. streptomycin, gentamycin, amikacin, validamycin, fortimicins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- A61P31/06—Antibacterial agents for tuberculosis
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Communicable Diseases (AREA)
- Molecular Biology (AREA)
- Oncology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Dispersion Chemistry (AREA)
- Pulmonology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Saccharide Compounds (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PCT/US1992/010591 WO1994012155A1 (en) | 1992-12-02 | 1992-12-02 | Antibiotic formulation and process |
| PCT/US1993/004501 WO1994012156A1 (en) | 1992-12-02 | 1993-05-11 | Antibiotic formulation and use for drug resistant infections |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK0671904T3 true DK0671904T3 (da) | 1999-12-06 |
Family
ID=22231603
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK93911272T DK0671904T3 (da) | 1992-12-02 | 1993-05-11 | Antibiotisk præparat og anvendelse mod lægemiddelresistente infektioner |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US5756121A (da) |
| EP (1) | EP0671904B1 (da) |
| JP (2) | JP4084846B2 (da) |
| AT (1) | ATE183082T1 (da) |
| AU (2) | AU3244393A (da) |
| CA (1) | CA2150832C (da) |
| DE (1) | DE69326017T2 (da) |
| DK (1) | DK0671904T3 (da) |
| ES (1) | ES2134846T3 (da) |
| GR (1) | GR3031548T3 (da) |
| WO (2) | WO1994012155A1 (da) |
Families Citing this family (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5958449A (en) * | 1992-12-02 | 1999-09-28 | Nexstar Pharmaceuticals, Inc. | Antibiotic formulation and use for bacterial infections |
| US6146890A (en) * | 1994-07-03 | 2000-11-14 | Danon; David | Method and system for cultivating macrophages |
| US5662929A (en) * | 1994-12-23 | 1997-09-02 | Universite De Montreal | Therapeutic liposomal formulation |
| US6726925B1 (en) * | 1998-06-18 | 2004-04-27 | Duke University | Temperature-sensitive liposomal formulation |
| ES2211151T3 (es) | 1998-08-19 | 2004-07-01 | Skyepharma Canada Inc. | Dispersiones acuosas inyectables de propofol. |
| US6613352B2 (en) | 1999-04-13 | 2003-09-02 | Universite De Montreal | Low-rigidity liposomal formulation |
| GB0111279D0 (en) * | 2001-05-10 | 2001-06-27 | Nycomed Imaging As | Radiolabelled liposomes |
| WO2003075889A1 (en) * | 2002-03-05 | 2003-09-18 | Transave, Inc. | An inhalation system for prevention and treatment of intracellular infections |
| US7718189B2 (en) | 2002-10-29 | 2010-05-18 | Transave, Inc. | Sustained release of antiinfectives |
| EP1581236B1 (en) * | 2002-10-29 | 2013-10-16 | Insmed Incorporated | Sustained release of antiinfectives |
| US7879351B2 (en) * | 2002-10-29 | 2011-02-01 | Transave, Inc. | High delivery rates for lipid based drug formulations, and methods of treatment thereof |
| JP4874547B2 (ja) * | 2002-11-26 | 2012-02-15 | ギリアード サイエンシーズ, インコーポレイテッド | 勾配によるリポソームへの薬物充填方法 |
| HUE029994T2 (en) | 2005-12-08 | 2017-04-28 | Insmed Inc | Lipid-based compositions of antiinfectives for treating pulmonary infections |
| WO2008137717A1 (en) * | 2007-05-04 | 2008-11-13 | Transave, Inc. | Compositions of multicationic drugs for reducing interactions with polyanionic biomolecules and methods and uses thereof |
| US9114081B2 (en) | 2007-05-07 | 2015-08-25 | Insmed Incorporated | Methods of treating pulmonary disorders with liposomal amikacin formulations |
| US9333214B2 (en) | 2007-05-07 | 2016-05-10 | Insmed Incorporated | Method for treating pulmonary disorders with liposomal amikacin formulations |
| US9119783B2 (en) | 2007-05-07 | 2015-09-01 | Insmed Incorporated | Method of treating pulmonary disorders with liposomal amikacin formulations |
| MX369828B (es) | 2012-05-21 | 2019-11-22 | Insmed Inc | Sistemas para tratar infecciones pulmonares. |
| KR102115718B1 (ko) | 2012-07-30 | 2020-05-28 | 마티나스 바이오파마 나노테크놀로지스, 인코포레이티드 | 대두 포스파티딜세린으로 제조된 코클리에이트 |
| RU2018135921A (ru) | 2012-11-29 | 2019-02-05 | Инсмед Инкорпорейтед | Стабилизированные составы ванкомицина |
| SMT202000516T1 (it) | 2014-05-15 | 2020-11-10 | Insmed Inc | Metodi per trattamento di infezioni micobatteriche polmonati non tubercolari |
| KR102367801B1 (ko) * | 2018-02-07 | 2022-02-24 | 제이에프이 스틸 가부시키가이샤 | 고Mn강 및 그의 제조 방법 |
| EP3773505B1 (en) | 2018-03-30 | 2026-04-29 | Insmed Incorporated | Methods for continuous manufacture of liposomal drug products |
| WO2019213398A1 (en) | 2018-05-02 | 2019-11-07 | Insmed Incorporated | Methods for the manufacture of liposomal drug formulations |
Family Cites Families (28)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5782311A (en) * | 1980-11-11 | 1982-05-22 | Tanabe Seiyaku Co Ltd | Production of liposome preparation |
| FR2521565B1 (fr) * | 1982-02-17 | 1985-07-05 | Dior Sa Parfums Christian | Melange pulverulent de constituants lipidiques et de constituants hydrophobes, procede pour le preparer, phases lamellaires lipidiques hydratees et procede de fabrication, compositions pharmaceutiques ou cosmetiques comportant des phases lamellaires lipidiques hydratees |
| US4522803A (en) * | 1983-02-04 | 1985-06-11 | The Liposome Company, Inc. | Stable plurilamellar vesicles, their preparation and use |
| FR2534487B1 (fr) * | 1982-10-15 | 1988-06-10 | Dior Christian Parfums | Procede d'homogeneisation de dispersions de phases lamellaires lipidiques hydratees, et suspensions obtenues par ce procede |
| US4981692A (en) * | 1983-03-24 | 1991-01-01 | The Liposome Company, Inc. | Therapeutic treatment by intramammary infusion |
| US4588578A (en) * | 1983-08-08 | 1986-05-13 | The Liposome Company, Inc. | Lipid vesicles prepared in a monophase |
| CA1237670A (en) * | 1983-05-26 | 1988-06-07 | Andrew S. Janoff | Drug preparations of reduced toxicity |
| CA1237671A (en) * | 1983-08-01 | 1988-06-07 | Michael W. Fountain | Enhancement of pharmaceutical activity |
| JPH0753661B2 (ja) * | 1984-03-08 | 1995-06-07 | フアレス フアーマスーチカル リサーチ エヌブイ | プロ―リポソーム組成物及びリポソームの水性分散物を作る方法 |
| JPS6176414A (ja) * | 1984-09-21 | 1986-04-18 | Shionogi & Co Ltd | リポソーム製剤の製法 |
| US4753788A (en) * | 1985-01-31 | 1988-06-28 | Vestar Research Inc. | Method for preparing small vesicles using microemulsification |
| US5409704A (en) * | 1985-06-26 | 1995-04-25 | The Liposome Company, Inc. | Liposomes comprising aminoglycoside phosphates and methods of production and use |
| US5023087A (en) * | 1986-02-10 | 1991-06-11 | Liposome Technology, Inc. | Efficient method for preparation of prolonged release liposome-based drug delivery system |
| US5043107A (en) * | 1986-08-21 | 1991-08-27 | Vestar Research, Inc. | Preparation small unilamellar vesicles including polyene antifungal antibiotics |
| US4933121A (en) * | 1986-12-10 | 1990-06-12 | Ciba Corning Diagnostics Corp. | Process for forming liposomes |
| IL97538A (en) * | 1986-12-23 | 1995-03-15 | Liposome Co Inc | Multilamellar liposomes containing nonphosphate guanindino aminoglycosides and their preparation. |
| US5043166A (en) * | 1987-01-09 | 1991-08-27 | Hadasit Medical Research, Inc. | Liposome/anthraquinone drug composition and method |
| DE3852037T2 (de) * | 1987-07-29 | 1995-03-23 | Liposome Co Inc | Verfahren zur trennung von teilchen nach grösse. |
| US4946683A (en) * | 1987-11-18 | 1990-08-07 | Vestar, Inc. | Multiple step entrapment/loading procedure for preparing lipophilic drug-containing liposomes |
| US5000887A (en) * | 1988-05-17 | 1991-03-19 | Liposome Technology, Inc. | Preparation of uniform-size liposomes |
| BE1001869A3 (fr) * | 1988-10-12 | 1990-04-03 | Franz Legros | Procede d'encapsulation liposomiale d'antibiotiques aminoglucosidiques, en particulier de la gentamycine. |
| US4952405A (en) * | 1988-10-20 | 1990-08-28 | Liposome Technology, Inc. | Method of treating M. avium infection |
| US5043165A (en) * | 1988-12-14 | 1991-08-27 | Liposome Technology, Inc. | Novel liposome composition for sustained release of steroidal drugs |
| US5270052A (en) * | 1991-04-19 | 1993-12-14 | New England Medical Center Hospitals, Inc. | Methods and compositions for treatment of infection by intracellular parasites |
| CA2093381A1 (en) * | 1992-04-07 | 1993-10-08 | Hideyuki Sawahara | Liposome formulation and process for production thereof |
| PT100486B (pt) * | 1992-05-14 | 1999-07-30 | Ineti Inst Nac Engenh E Tecnol | Aminoglucosidos lipossomais com altas eficacia de encapsulacao e actividade terapeutica, nomeadamente a netilmicina, e processo para a sua preparcao |
| US5276452A (en) * | 1992-06-24 | 1994-01-04 | Raytheon Company | Scan compensation for array antenna on a curved surface |
| JP3325665B2 (ja) * | 1993-09-10 | 2002-09-17 | 三菱化学株式会社 | オレフィン重合用触媒およびこれを用いたオレフィン重合体の製造方法 |
-
1992
- 1992-12-02 AU AU32443/93A patent/AU3244393A/en not_active Abandoned
- 1992-12-02 WO PCT/US1992/010591 patent/WO1994012155A1/en not_active Ceased
-
1993
- 1993-05-11 DK DK93911272T patent/DK0671904T3/da active
- 1993-05-11 DE DE69326017T patent/DE69326017T2/de not_active Expired - Lifetime
- 1993-05-11 ES ES93911272T patent/ES2134846T3/es not_active Expired - Lifetime
- 1993-05-11 CA CA002150832A patent/CA2150832C/en not_active Expired - Lifetime
- 1993-05-11 EP EP93911272A patent/EP0671904B1/en not_active Expired - Lifetime
- 1993-05-11 JP JP51309394A patent/JP4084846B2/ja not_active Expired - Lifetime
- 1993-05-11 WO PCT/US1993/004501 patent/WO1994012156A1/en not_active Ceased
- 1993-05-11 AT AT93911272T patent/ATE183082T1/de active
- 1993-05-11 AU AU42463/93A patent/AU668179B2/en not_active Expired
-
1995
- 1995-06-06 US US08/469,157 patent/US5756121A/en not_active Expired - Lifetime
-
1999
- 1999-10-15 GR GR990402641T patent/GR3031548T3/el unknown
-
2005
- 2005-06-08 JP JP2005167807A patent/JP2005320341A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| DE69326017D1 (de) | 1999-09-16 |
| JP2005320341A (ja) | 2005-11-17 |
| AU3244393A (en) | 1994-06-22 |
| WO1994012155A1 (en) | 1994-06-09 |
| ES2134846T3 (es) | 1999-10-16 |
| WO1994012156A1 (en) | 1994-06-09 |
| JP4084846B2 (ja) | 2008-04-30 |
| DE69326017T2 (de) | 1999-12-23 |
| US5756121A (en) | 1998-05-26 |
| EP0671904B1 (en) | 1999-08-11 |
| AU4246393A (en) | 1994-06-22 |
| CA2150832A1 (en) | 1994-06-09 |
| AU668179B2 (en) | 1996-04-26 |
| CA2150832C (en) | 2000-01-11 |
| ATE183082T1 (de) | 1999-08-15 |
| JPH09506855A (ja) | 1997-07-08 |
| EP0671904A1 (en) | 1995-09-20 |
| GR3031548T3 (en) | 2000-01-31 |
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