DK0671905T3 - Stabile protein:pholipidsammensætninger samt fremgangsmåder - Google Patents
Stabile protein:pholipidsammensætninger samt fremgangsmåderInfo
- Publication number
- DK0671905T3 DK0671905T3 DK94929959T DK94929959T DK0671905T3 DK 0671905 T3 DK0671905 T3 DK 0671905T3 DK 94929959 T DK94929959 T DK 94929959T DK 94929959 T DK94929959 T DK 94929959T DK 0671905 T3 DK0671905 T3 DK 0671905T3
- Authority
- DK
- Denmark
- Prior art keywords
- protein
- compositions
- pholipid
- methods
- stable protein
- Prior art date
Links
- 102000004169 proteins and genes Human genes 0.000 title abstract 6
- 108090000623 proteins and genes Proteins 0.000 title abstract 6
- 239000000203 mixture Substances 0.000 title abstract 4
- 238000000034 method Methods 0.000 title abstract 2
- 238000004220 aggregation Methods 0.000 abstract 1
- 230000002776 aggregation Effects 0.000 abstract 1
- 238000004925 denaturation Methods 0.000 abstract 1
- 230000036425 denaturation Effects 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 238000009472 formulation Methods 0.000 abstract 1
- 150000002632 lipids Chemical class 0.000 abstract 1
- 150000003904 phospholipids Chemical class 0.000 abstract 1
- 230000000087 stabilizing effect Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/19—Cytokines; Lymphokines; Interferons
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/19—Cytokines; Lymphokines; Interferons
- A61K38/193—Colony stimulating factors [CSF]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/56—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
- A61K47/59—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes
- A61K47/60—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes the organic macromolecular compound being a polyoxyalkylene oligomer, polymer or dendrimer, e.g. PEG, PPG, PEO or polyglycerol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Zoology (AREA)
- Dispersion Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Immunology (AREA)
- Gastroenterology & Hepatology (AREA)
- Organic Chemistry (AREA)
- Diabetes (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Hematology (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US13241393A | 1993-10-06 | 1993-10-06 | |
| PCT/US1994/011081 WO1995009611A2 (en) | 1993-10-06 | 1994-09-29 | Stable protein: phospholipid compositions and methods |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK0671905T3 true DK0671905T3 (da) | 2002-10-07 |
Family
ID=22453938
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK94929959T DK0671905T3 (da) | 1993-10-06 | 1994-09-29 | Stabile protein:pholipidsammensætninger samt fremgangsmåder |
Country Status (20)
| Country | Link |
|---|---|
| EP (1) | EP0671905B1 (da) |
| JP (1) | JP2852127B2 (da) |
| KR (1) | KR100372006B1 (da) |
| CN (1) | CN1206982C (da) |
| AT (1) | ATE222752T1 (da) |
| AU (1) | AU683698B2 (da) |
| CA (1) | CA2150939C (da) |
| CZ (1) | CZ290029B6 (da) |
| DE (1) | DE69431236T2 (da) |
| DK (1) | DK0671905T3 (da) |
| ES (1) | ES2184768T3 (da) |
| FI (1) | FI116271B (da) |
| HU (1) | HUT72326A (da) |
| IL (1) | IL111170A (da) |
| NO (1) | NO314064B1 (da) |
| NZ (1) | NZ274705A (da) |
| PT (1) | PT671905E (da) |
| RU (1) | RU2119791C1 (da) |
| WO (1) | WO1995009611A2 (da) |
| ZA (1) | ZA947782B (da) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5874075A (en) * | 1993-10-06 | 1999-02-23 | Amgen Inc. | Stable protein: phospholipid compositions and methods |
| EP0937456B1 (en) * | 1998-02-23 | 2004-07-21 | Cilag AG International | Erythropoietin liposomal dispersion |
| CA2333162C (en) * | 1998-05-25 | 2011-07-26 | Nippon Shinyaku Co., Ltd. | Process for producing composite preparation containing nucleic acid |
| GB0118517D0 (en) * | 2001-07-30 | 2001-09-19 | Mitsubishi Tokyo Pharm Inc | Compound |
| US7972593B2 (en) | 2004-06-10 | 2011-07-05 | Saint Louis University | Delivery of therapeutic agents to the bone |
| US7863238B2 (en) | 2004-06-10 | 2011-01-04 | Saint Louis University | Proteins with an attached short peptide of acidic amino acids |
| JP2006248978A (ja) * | 2005-03-10 | 2006-09-21 | Mebiopharm Co Ltd | 新規なリポソーム製剤 |
| CN101990425B (zh) | 2008-04-08 | 2016-01-20 | 默克专利股份有限公司 | 包含环肽的组合物和使用方法 |
| JP2015519361A (ja) * | 2012-05-31 | 2015-07-09 | エイジェンシー・フォー・サイエンス,テクノロジー・アンド・リサーチ | 正電荷有機添加剤での処理によるタンパク質製剤におけるタンパク質−不純物複合体及び凝集体のレベルを低下させるための方法 |
| CA2946275A1 (en) * | 2014-04-04 | 2015-10-08 | Osaka University | Drug delivery enhancer comprising substance for activating lysophospholipid receptors |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2046324A1 (en) * | 1989-01-26 | 1990-07-27 | Wen-Ghih Tsang | Stabilization of aqueous-based hydrophobic protein solutions and sustained release vehicle |
| WO1991008754A1 (fr) * | 1989-12-13 | 1991-06-27 | Otsuka Pharmaceutical Co., Ltd. | Application medicinale de m-csf |
| DE4208527A1 (de) | 1992-03-17 | 1993-09-23 | Max Planck Gesellschaft | Liposomen mit negativer ueberschussladung |
| JPH06247842A (ja) * | 1993-02-23 | 1994-09-06 | Green Cross Corp:The | リポソーム組成物の製造方法 |
-
1994
- 1994-09-29 HU HU9502053A patent/HUT72326A/hu unknown
- 1994-09-29 DE DE69431236T patent/DE69431236T2/de not_active Expired - Fee Related
- 1994-09-29 RU RU95117866A patent/RU2119791C1/ru not_active IP Right Cessation
- 1994-09-29 ES ES94929959T patent/ES2184768T3/es not_active Expired - Lifetime
- 1994-09-29 AU AU79239/94A patent/AU683698B2/en not_active Ceased
- 1994-09-29 CA CA002150939A patent/CA2150939C/en not_active Expired - Fee Related
- 1994-09-29 NZ NZ274705A patent/NZ274705A/en not_active IP Right Cessation
- 1994-09-29 AT AT94929959T patent/ATE222752T1/de not_active IP Right Cessation
- 1994-09-29 JP JP7510908A patent/JP2852127B2/ja not_active Expired - Lifetime
- 1994-09-29 CZ CZ19951438A patent/CZ290029B6/cs not_active IP Right Cessation
- 1994-09-29 KR KR1019950702281A patent/KR100372006B1/ko not_active Expired - Fee Related
- 1994-09-29 CN CNB941911012A patent/CN1206982C/zh not_active Expired - Fee Related
- 1994-09-29 DK DK94929959T patent/DK0671905T3/da active
- 1994-09-29 PT PT94929959T patent/PT671905E/pt unknown
- 1994-09-29 EP EP94929959A patent/EP0671905B1/en not_active Expired - Lifetime
- 1994-09-29 WO PCT/US1994/011081 patent/WO1995009611A2/en not_active Ceased
- 1994-10-04 IL IL11117094A patent/IL111170A/xx not_active IP Right Cessation
- 1994-10-05 ZA ZA947782A patent/ZA947782B/xx unknown
-
1995
- 1995-06-02 NO NO19952210A patent/NO314064B1/no not_active IP Right Cessation
- 1995-06-05 FI FI952738A patent/FI116271B/fi active IP Right Grant
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