DK0673376T3 - Bicykliske pyrimidinforbindelser, fremgangsmåde til fremstilling heraf og farmaceutiske midler, som omfatter dem - Google Patents

Bicykliske pyrimidinforbindelser, fremgangsmåde til fremstilling heraf og farmaceutiske midler, som omfatter dem

Info

Publication number
DK0673376T3
DK0673376T3 DK94902003.6T DK94902003T DK0673376T3 DK 0673376 T3 DK0673376 T3 DK 0673376T3 DK 94902003 T DK94902003 T DK 94902003T DK 0673376 T3 DK0673376 T3 DK 0673376T3
Authority
DK
Denmark
Prior art keywords
pct
processes
preparation
pyrimidine compounds
pharmaceutical agents
Prior art date
Application number
DK94902003.6T
Other languages
English (en)
Inventor
Gilbert Regnier
Alain Dhainaut
Ghanem Atassi
Alain Pierre
Original Assignee
Adir
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Adir filed Critical Adir
Application granted granted Critical
Publication of DK0673376T3 publication Critical patent/DK0673376T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • C07D473/02—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
    • C07D473/16—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two nitrogen atoms

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
DK94902003.6T 1992-12-11 1993-12-09 Bicykliske pyrimidinforbindelser, fremgangsmåde til fremstilling heraf og farmaceutiske midler, som omfatter dem DK0673376T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9214913A FR2699176B1 (fr) 1992-12-11 1992-12-11 Nouveaux composés bicycliques de pyrimidine, leur procédé de préparation et les compositions pharmaceutiques les renfermant.

Publications (1)

Publication Number Publication Date
DK0673376T3 true DK0673376T3 (da) 1996-10-07

Family

ID=9436453

Family Applications (1)

Application Number Title Priority Date Filing Date
DK94902003.6T DK0673376T3 (da) 1992-12-11 1993-12-09 Bicykliske pyrimidinforbindelser, fremgangsmåde til fremstilling heraf og farmaceutiske midler, som omfatter dem

Country Status (13)

Country Link
US (1) US5508277A (da)
EP (1) EP0673376B1 (da)
JP (1) JPH08504426A (da)
AT (1) ATE138380T1 (da)
AU (1) AU666422B2 (da)
CA (1) CA2117462A1 (da)
DE (1) DE69302829T2 (da)
DK (1) DK0673376T3 (da)
ES (1) ES2091126T3 (da)
FR (1) FR2699176B1 (da)
GR (1) GR3020330T3 (da)
NZ (1) NZ258595A (da)
WO (1) WO1994013668A1 (da)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE9110772U1 (de) * 1991-08-30 1991-11-14 Wolf - Geräte GmbH Vertriebsgesellschaft KG, 5240 Betzdorf Gartenschere
FR2699176B1 (fr) * 1992-12-11 1995-03-03 Adir Nouveaux composés bicycliques de pyrimidine, leur procédé de préparation et les compositions pharmaceutiques les renfermant.
US5866702A (en) * 1996-08-02 1999-02-02 Cv Therapeutics, Incorporation Purine inhibitors of cyclin dependent kinase 2
US6794390B2 (en) * 1996-08-02 2004-09-21 Cv Therapeutics, Inc. Purine inhibitors of cyclin dependent kinase 2 & ikappabalpha
AU2002322720B2 (en) 2001-07-25 2008-11-13 Raptor Pharmaceutical Inc. Compositions and methods for modulating blood-brain barrier transport
CN102379684B (zh) 2005-04-28 2014-11-19 普罗透斯数字保健公司 药物信息系统
US7932257B2 (en) 2005-07-22 2011-04-26 Sunesis Pharmaceuticals, Inc. Substituted pyrazolo[4,3-d]pyrimidines as aurora kinase inhibitors
KR20090071598A (ko) 2006-09-18 2009-07-01 랩터 파마슈티컬 인코포레이티드 수용체 결합 단백질(ｒａｐ)-접합체 투여에 의한 간 질환의 치료
EP2398500B1 (en) 2009-02-20 2019-03-13 2-BBB Medicines B.V. Glutathione-based drug delivery system
WO2010114894A1 (en) 2009-03-31 2010-10-07 Arqule, Inc. Substituted heterocyclic compounds
ES2942923T3 (es) 2009-05-06 2023-06-07 Laboratory Skin Care Inc Composiciones de administración dérmica que comprenden complejos de agente activo-partículas de fosfato de calcio y métodos de uso de las mismas
US20120077778A1 (en) 2010-09-29 2012-03-29 Andrea Bourdelais Ladder-Frame Polyether Conjugates
US20250213546A1 (en) * 2022-04-01 2025-07-03 Drexel University Treating cancer with small molecules that inhibit acss-2

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1544419A (en) * 1975-11-19 1979-04-19 Science Union & Cie Purines and pyrazolo-pyrimidines a process for their preparation and pharmaceutical compositions containing them
DE2804416A1 (de) * 1978-02-02 1979-08-09 Boehringer Mannheim Gmbh Neue purin-derivate, verfahren zu deren herstellung sowie diese verbindungen enthaltende arzneimittel
US5204353A (en) * 1987-04-07 1993-04-20 Ciba-Geigy Corporation 3-benzyl-3H-1,2,3-triazolo[4,5-d]pyrimidines, compositions thereof, and method of treating epilepsy therewith
US4999363A (en) * 1988-06-09 1991-03-12 Kyowa Hakko Kogyo Co., Ltd. Tricyclic compounds
EP0363320A3 (de) * 1988-10-06 1991-11-21 Ciba-Geigy Ag Substituierte 9H-Purine
FR2643373B1 (fr) * 1989-01-10 1993-12-31 Adir Cie Nouveaux derives des bisarylalcenes, leurs procedes de preparation et les compositions pharmaceutiques qui les contiennent
US5256650A (en) * 1989-03-29 1993-10-26 Merrell Dow Pharmaceuticals Inc. Selective adenosine receptor agents
KR970009225B1 (ko) * 1989-09-19 1997-06-09 데이진 가부시끼가이샤 피롤로[2,3-디] 피리미딘 유도체, 그의 제조방법 및 그것을 유효성분으로 하는 의약제제
EP0495982B1 (en) * 1989-10-11 1996-06-12 Teijin Limited Bicyclic pyrimidine derivative, method of producing the same, and pharmaceutical preparation containing the same as active ingredient
US5397782A (en) * 1990-06-13 1995-03-14 Janssen Pharmaceutica N.V. Method of treating addiction to alcohol
US5217980A (en) * 1990-07-19 1993-06-08 Janssen Pharmaceutica N.V. Oxazolyl and piperidinyl substituted benimidazolyl compounds
EP0514542B1 (en) * 1990-12-06 1996-10-23 Sony Corporation Feedback clamping circuit
FR2699176B1 (fr) * 1992-12-11 1995-03-03 Adir Nouveaux composés bicycliques de pyrimidine, leur procédé de préparation et les compositions pharmaceutiques les renfermant.

Also Published As

Publication number Publication date
JPH08504426A (ja) 1996-05-14
DE69302829D1 (de) 1996-06-27
WO1994013668A1 (fr) 1994-06-23
EP0673376B1 (fr) 1996-05-22
US5508277A (en) 1996-04-16
NZ258595A (en) 1996-04-26
FR2699176A1 (fr) 1994-06-17
AU5653594A (en) 1994-07-04
AU666422B2 (en) 1996-02-08
CA2117462A1 (fr) 1994-06-23
FR2699176B1 (fr) 1995-03-03
ES2091126T3 (es) 1996-10-16
EP0673376A1 (fr) 1995-09-27
DE69302829T2 (de) 1996-11-28
ATE138380T1 (de) 1996-06-15
GR3020330T3 (en) 1996-09-30

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