DK0912509T3 - Distamycinderivater, fremgangsmåde til fremstilling deraf og deres anvendelse som antitumor- og antivirale midler - Google Patents
Distamycinderivater, fremgangsmåde til fremstilling deraf og deres anvendelse som antitumor- og antivirale midlerInfo
- Publication number
- DK0912509T3 DK0912509T3 DK97920753T DK97920753T DK0912509T3 DK 0912509 T3 DK0912509 T3 DK 0912509T3 DK 97920753 T DK97920753 T DK 97920753T DK 97920753 T DK97920753 T DK 97920753T DK 0912509 T3 DK0912509 T3 DK 0912509T3
- Authority
- DK
- Denmark
- Prior art keywords
- antitumor
- processes
- preparation
- antiviral agents
- distamycin derivatives
- Prior art date
Links
- 230000000259 anti-tumor effect Effects 0.000 title 1
- 239000002246 antineoplastic agent Substances 0.000 title 1
- 239000003443 antiviral agent Substances 0.000 title 1
- UPBAOYRENQEPJO-UHFFFAOYSA-N n-[5-[[5-[(3-amino-3-iminopropyl)carbamoyl]-1-methylpyrrol-3-yl]carbamoyl]-1-methylpyrrol-3-yl]-4-formamido-1-methylpyrrole-2-carboxamide Chemical class CN1C=C(NC=O)C=C1C(=O)NC1=CN(C)C(C(=O)NC2=CN(C)C(C(=O)NCCC(N)=N)=C2)=C1 UPBAOYRENQEPJO-UHFFFAOYSA-N 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
- C07D207/34—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Virology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
- Pyrrole Compounds (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB9610079.7A GB9610079D0 (en) | 1996-05-14 | 1996-05-14 | Distamycin deriratives process for preparing them and their use as antitumor and antiviral agents |
| PCT/EP1997/002158 WO1997043258A1 (en) | 1996-05-14 | 1997-04-24 | Distamycin derivatives, process for preparing them, and their use as antitumor and antiviral agents |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK0912509T3 true DK0912509T3 (da) | 2001-10-22 |
Family
ID=10793694
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK97920753T DK0912509T3 (da) | 1996-05-14 | 1997-04-24 | Distamycinderivater, fremgangsmåde til fremstilling deraf og deres anvendelse som antitumor- og antivirale midler |
Country Status (26)
| Country | Link |
|---|---|
| US (1) | US6177408B1 (da) |
| EP (1) | EP0912509B1 (da) |
| JP (1) | JP2000510129A (da) |
| CN (1) | CN1089755C (da) |
| AR (1) | AR007108A1 (da) |
| AT (1) | ATE203011T1 (da) |
| AU (1) | AU721140B2 (da) |
| BR (1) | BR9709451A (da) |
| CA (1) | CA2253652A1 (da) |
| DE (1) | DE69705622T2 (da) |
| DK (1) | DK0912509T3 (da) |
| EA (1) | EA002273B1 (da) |
| ES (1) | ES2160951T3 (da) |
| GB (1) | GB9610079D0 (da) |
| GR (1) | GR3036824T3 (da) |
| HU (1) | HUP9901387A3 (da) |
| IL (1) | IL126840A (da) |
| MY (1) | MY118004A (da) |
| NO (1) | NO311886B1 (da) |
| NZ (1) | NZ332923A (da) |
| PL (1) | PL329878A1 (da) |
| PT (1) | PT912509E (da) |
| TW (1) | TW498066B (da) |
| UA (1) | UA45457C2 (da) |
| WO (1) | WO1997043258A1 (da) |
| ZA (1) | ZA973883B (da) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9806692D0 (en) * | 1998-03-27 | 1998-05-27 | Pharmacia & Upjohn Spa | Benzoheterocyclic distamycin derivatives, process for preparing them and their use as antitumour agents |
| GB9806689D0 (en) * | 1998-03-27 | 1998-05-27 | Pharmacia & Upjohn Spa | Acryloyl derivatives analogous to distamycin,process for preparing them,and their use as antitumour and antiviral agents |
| GB9812211D0 (en) * | 1998-06-05 | 1998-08-05 | Pharmacia & Upjohn Spa | Cinnamoyl distamycin analogous derivatives,process for their preparation,and their use as antitumor agents |
| GB9816652D0 (en) * | 1998-07-30 | 1998-09-30 | Pharmacia & Upjohn Spa | Sulfurated distamycin derivatives process for preparing them and their use as antitumor agents |
| GB9816653D0 (en) * | 1998-07-30 | 1998-09-30 | Pharmacia & Upjohn Spa | Oxidised sulfurated distamycin derivatives process for preparing them and their use as antitumor agents |
| GB9928703D0 (en) * | 1999-12-03 | 2000-02-02 | Pharmacia & Upjohn Spa | Acryloyl peptidic derivatives,process for their preparation and their use as antitumour agents |
| US6559125B1 (en) | 2000-01-28 | 2003-05-06 | California Institute Of Technology | Polyamide-alkylator conjugates and related products and method |
| GB0011059D0 (en) | 2000-05-08 | 2000-06-28 | Pharmacia & Upjohn Spa | Use of substituted acryloyl distamycin derivatives in the treatment of tumours associated with high levels of glutathione |
| GB0015446D0 (en) | 2000-06-23 | 2000-08-16 | Pharmacia & Upjohn Spa | Combined therapy against tumors comprising substituted acryloyl distamycin derivates,taxanes and/or antimetabolites |
| GB0015447D0 (en) | 2000-06-23 | 2000-08-16 | Pharmacia & Upjohn Spa | Combined therapy against tumors comprising substituted acryloyl derivates and alkylating agents |
| GB0016447D0 (en) | 2000-07-04 | 2000-08-23 | Pharmacia & Upjohn Spa | Process for preparing distamycin derivatives |
| GB0017852D0 (en) * | 2000-07-20 | 2000-09-06 | Pharmacia & Upjohn Spa | Process for preparing distamycin derivatives |
| GB0029004D0 (en) | 2000-11-28 | 2001-01-10 | Pharmacia & Upjohn Spa | Process for preparing distamycin derivatives |
| EP1470119A4 (en) * | 2001-06-13 | 2005-10-19 | Genesoft Pharmaceuticals Inc | BENZOTHIOPHENE COMPOUNDS WITH ANTI-INFECTIOUS ACTIVITY |
| US20030236198A1 (en) * | 2001-06-13 | 2003-12-25 | Genesoft, Inc. | Antipathogenic benzamide compounds |
| US6969592B2 (en) | 2001-09-26 | 2005-11-29 | Pharmacia Italia S.P.A. | Method for predicting the sensitivity to chemotherapy |
| KR102573190B1 (ko) | 2015-10-16 | 2023-09-01 | 삼성전자주식회사 | 전자장치 및 전자장치 제조방법 |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB8612218D0 (en) * | 1986-05-20 | 1986-06-25 | Erba Farmitalia | Site specific alkylating agents |
| GB9416005D0 (en) * | 1994-08-08 | 1994-09-28 | Erba Carlo Spa | Peptidic compounds analogous to distamycin a and process for their preparation |
-
1996
- 1996-05-14 GB GBGB9610079.7A patent/GB9610079D0/en active Pending
-
1997
- 1997-04-24 US US09/147,264 patent/US6177408B1/en not_active Expired - Fee Related
- 1997-04-24 IL IL12684097A patent/IL126840A/en not_active IP Right Cessation
- 1997-04-24 DE DE69705622T patent/DE69705622T2/de not_active Expired - Fee Related
- 1997-04-24 ES ES97920753T patent/ES2160951T3/es not_active Expired - Lifetime
- 1997-04-24 CA CA002253652A patent/CA2253652A1/en not_active Abandoned
- 1997-04-24 HU HU9901387A patent/HUP9901387A3/hu unknown
- 1997-04-24 AU AU27016/97A patent/AU721140B2/en not_active Ceased
- 1997-04-24 EP EP97920753A patent/EP0912509B1/en not_active Expired - Lifetime
- 1997-04-24 UA UA98126575A patent/UA45457C2/uk unknown
- 1997-04-24 WO PCT/EP1997/002158 patent/WO1997043258A1/en not_active Ceased
- 1997-04-24 NZ NZ332923A patent/NZ332923A/xx unknown
- 1997-04-24 PL PL97329878A patent/PL329878A1/xx unknown
- 1997-04-24 EA EA199801013A patent/EA002273B1/ru not_active IP Right Cessation
- 1997-04-24 PT PT97920753T patent/PT912509E/pt unknown
- 1997-04-24 JP JP09540439A patent/JP2000510129A/ja not_active Withdrawn
- 1997-04-24 CN CN97195530A patent/CN1089755C/zh not_active Expired - Fee Related
- 1997-04-24 AT AT97920753T patent/ATE203011T1/de not_active IP Right Cessation
- 1997-04-24 DK DK97920753T patent/DK0912509T3/da active
- 1997-04-24 BR BR9709451A patent/BR9709451A/pt not_active Application Discontinuation
- 1997-05-05 TW TW086106038A patent/TW498066B/zh not_active IP Right Cessation
- 1997-05-06 ZA ZA9703883A patent/ZA973883B/xx unknown
- 1997-05-13 MY MYPI97002075A patent/MY118004A/en unknown
- 1997-05-13 AR ARP970101989A patent/AR007108A1/es unknown
-
1998
- 1998-11-13 NO NO19985307A patent/NO311886B1/no unknown
-
2001
- 2001-10-08 GR GR20010401685T patent/GR3036824T3/el not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| CN1222144A (zh) | 1999-07-07 |
| AU2701697A (en) | 1997-12-05 |
| DE69705622T2 (de) | 2002-05-08 |
| ZA973883B (en) | 1997-12-08 |
| PT912509E (pt) | 2001-12-28 |
| NO311886B1 (no) | 2002-02-11 |
| EP0912509B1 (en) | 2001-07-11 |
| CN1089755C (zh) | 2002-08-28 |
| JP2000510129A (ja) | 2000-08-08 |
| CA2253652A1 (en) | 1997-11-20 |
| HUP9901387A2 (hu) | 2000-04-28 |
| ATE203011T1 (de) | 2001-07-15 |
| BR9709451A (pt) | 1999-08-10 |
| AR007108A1 (es) | 1999-10-13 |
| GR3036824T3 (en) | 2002-01-31 |
| ES2160951T3 (es) | 2001-11-16 |
| HUP9901387A3 (en) | 2002-10-28 |
| DE69705622D1 (de) | 2001-08-16 |
| GB9610079D0 (en) | 1996-07-17 |
| US6177408B1 (en) | 2001-01-23 |
| NZ332923A (en) | 2000-03-27 |
| PL329878A1 (en) | 1999-04-12 |
| NO985307L (no) | 1999-01-12 |
| EA002273B1 (ru) | 2002-02-28 |
| TW498066B (en) | 2002-08-11 |
| NO985307D0 (no) | 1998-11-13 |
| HK1020734A1 (en) | 2000-05-19 |
| UA45457C2 (uk) | 2002-04-15 |
| IL126840A0 (en) | 1999-09-22 |
| IL126840A (en) | 2002-03-10 |
| AU721140B2 (en) | 2000-06-22 |
| MY118004A (en) | 2004-08-30 |
| EA199801013A1 (ru) | 1999-06-24 |
| EP0912509A1 (en) | 1999-05-06 |
| WO1997043258A1 (en) | 1997-11-20 |
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