NO991815L - Oksadiazoler, fremgangsmÕter for deres fremstilling og deres anvendelse som medikamenter - Google Patents

Oksadiazoler, fremgangsmÕter for deres fremstilling og deres anvendelse som medikamenter

Info

Publication number
NO991815L
NO991815L NO991815A NO991815A NO991815L NO 991815 L NO991815 L NO 991815L NO 991815 A NO991815 A NO 991815A NO 991815 A NO991815 A NO 991815A NO 991815 L NO991815 L NO 991815L
Authority
NO
Norway
Prior art keywords
oxadiazoles
drugs
processes
preparation
Prior art date
Application number
NO991815A
Other languages
English (en)
Other versions
NO312512B1 (no
NO991815D0 (no
Inventor
Michael Brenner
Roland Maier
Marion Wienrich
Thomas Weiser
Rainer Palluk
Wolf-Dietrich Bechtel
Angelo Sagrada
Helmut Ensinger
Uwe Pschorn
Raffaele Cesana
Original Assignee
Boehringer Ingelheim Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Ingelheim Pharma filed Critical Boehringer Ingelheim Pharma
Publication of NO991815L publication Critical patent/NO991815L/no
Publication of NO991815D0 publication Critical patent/NO991815D0/no
Publication of NO312512B1 publication Critical patent/NO312512B1/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D271/00—Heterocyclic compounds containing five-membered rings having two nitrogen atoms and one oxygen atom as the only ring hetero atoms
    • C07D271/02—Heterocyclic compounds containing five-membered rings having two nitrogen atoms and one oxygen atom as the only ring hetero atoms not condensed with other rings
    • C07D271/06—1,2,4-Oxadiazoles; Hydrogenated 1,2,4-oxadiazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Neurology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biomedical Technology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Cardiology (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
NO19991815A 1996-10-18 1999-04-16 Oksadiazoler, anvendelse derav, fremgangsmåte for deres fremstilling, samt farmasöytiske preparater NO312512B1 (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19643037A DE19643037A1 (de) 1996-10-18 1996-10-18 Neue Oxadiazole, Verfahren zu ihrer Herstellung sowie deren Verwendung als Arzneimittel
PCT/EP1997/005693 WO1998017652A1 (de) 1996-10-18 1997-10-15 Oxadiazole, verfahren zu ihrer herstellung sowie ihre verwendung als arzneimittel

Publications (3)

Publication Number Publication Date
NO991815L true NO991815L (no) 1999-04-16
NO991815D0 NO991815D0 (no) 1999-04-16
NO312512B1 NO312512B1 (no) 2002-05-21

Family

ID=7809114

Family Applications (1)

Application Number Title Priority Date Filing Date
NO19991815A NO312512B1 (no) 1996-10-18 1999-04-16 Oksadiazoler, anvendelse derav, fremgangsmåte for deres fremstilling, samt farmasöytiske preparater

Country Status (31)

Country Link
US (1) US6277872B1 (no)
EP (1) EP0934288B1 (no)
JP (1) JP3333523B2 (no)
KR (1) KR20000049253A (no)
CN (1) CN1086698C (no)
AR (1) AR008496A1 (no)
AT (1) ATE315034T1 (no)
AU (1) AU737552B2 (no)
BG (1) BG103251A (no)
BR (1) BR9714354A (no)
CA (1) CA2268954C (no)
CO (1) CO4920253A1 (no)
CZ (1) CZ138099A3 (no)
DE (2) DE19643037A1 (no)
EE (1) EE9900147A (no)
ES (1) ES2256880T3 (no)
HR (1) HRP970553A2 (no)
HU (1) HUP0001652A3 (no)
ID (1) ID18613A (no)
IL (1) IL129315A0 (no)
NO (1) NO312512B1 (no)
NZ (1) NZ335598A (no)
PE (1) PE11199A1 (no)
PL (1) PL332432A1 (no)
RU (1) RU2182905C2 (no)
SK (1) SK49999A3 (no)
TR (1) TR199900848T2 (no)
TW (1) TW413678B (no)
WO (1) WO1998017652A1 (no)
YU (1) YU40997A (no)
ZA (1) ZA979220B (no)

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US6660753B2 (en) 1999-08-19 2003-12-09 Nps Pharmaceuticals, Inc. Heteropolycyclic compounds and their use as metabotropic glutamate receptor antagonists
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ES2320973T3 (es) 2000-06-12 2009-06-01 EISAI R&D MANAGEMENT CO., LTD. Compuestos de 1,2-dihidropiridina, procedimiento para su preparacion y uso de los mismos.
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JP4303109B2 (ja) * 2001-10-04 2009-07-29 メルク エンド カムパニー インコーポレーテッド 代謝共役型グルタミン酸受容体−５のヘテロアリール置換テトラゾール調節剤
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HRP20050168A2 (en) 2002-08-23 2005-10-31 Rigel Pharmaceuticals Pyridyl substituted heterocycles useful for treating or preventing hcv infection
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RU2338746C2 (ru) * 2003-02-27 2008-11-20 НьюроСёрч А/С Новые диазабициклические арильные производные, содержащие их фармацевтические композиции и их применение
US7326790B2 (en) 2003-05-02 2008-02-05 Rigel Pharmaceuticals, Inc. Diphenylisoxazole compounds and hydro isomers thereof
US7115642B2 (en) 2003-05-02 2006-10-03 Rigel Pharmaceuticals, Inc. Substituted diphenyl isoxazoles, pyrazoles and oxadiazoles useful for treating HCV infection
US7220745B2 (en) 2003-05-15 2007-05-22 Rigel Pharmaceuticals Heterocyclic compounds useful to treat HCV
WO2005049065A2 (en) 2003-11-19 2005-06-02 Rigel Pharmaceuticals, Inc. Synergistic combinations of dihaloacetamide with interferon or ribavirin for treatment hcv infections
JP4958560B2 (ja) * 2003-12-24 2012-06-20 プロシディオン・リミテッド Ｇｐｃｒ受容体作動薬としてのヘテロ環誘導体
US7514434B2 (en) 2004-02-23 2009-04-07 Rigel Pharmaceuticals, Inc. Heterocyclic compounds having an oxadiazole moiety and hydro isomers thereof
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JP2008540425A (ja) 2005-05-02 2008-11-20 ライジェル ファーマシューティカルズ， インコーポレイテッド 代謝可能部分を含む複素環式抗ウイルス性化合物およびその使用
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US20110207704A1 (en) * 2006-12-15 2011-08-25 Abbott Laboratories Novel Oxadiazole Compounds
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WO2009082398A1 (en) * 2007-12-21 2009-07-02 University Of Notre Dame Du Lac Antibacterial compounds and methods of using same
EP2687513B1 (en) 2008-06-09 2020-12-02 Ludwig-Maximilians-Universität München Drugs for inhibiting aggregation of proteins involved in diseases linked to protein aggregation and/or neurodegenerative diseases
RU2398770C1 (ru) * 2009-03-27 2010-09-10 Учреждение Российской академии наук Институт молекулярной генетики РАН (ИМГ РАН) Меченная тритием 3-[5-(2-фторфенил)-1,2,4-оксадиазол-3-ил]бензойная кислота
US9095596B2 (en) * 2009-10-15 2015-08-04 Southern Research Institute Treatment of neurodegenerative diseases, causation of memory enhancement, and assay for screening compounds for such
MX365851B (es) * 2012-08-24 2019-06-17 Treventis Corp Compuestos de benzofurazano anti-amiloides y metodos.
RS58976B1 (sr) 2014-02-27 2019-08-30 Treventis Corp Antiamiloidna jedinjenja koja sadrže benzofuran
BR112016022451B1 (pt) 2014-04-24 2021-03-30 Sumitomo Chemical Company, Limited Composto de diaril-azol e agente de controle de peste artrópoda
AU2015319834A1 (en) * 2014-09-25 2017-04-20 University Of Notre Dame Du Lac Non-beta lactam antibiotics
CN107286174B (zh) * 2016-04-11 2020-08-18 上海勋和医药科技有限公司 取代2,4-(1h,3h)嘧啶二酮作为parp抑制剂及其应用
WO2018049404A1 (en) 2016-09-12 2018-03-15 University Of Notre Dame Du Lac Compounds for the treatment of clostridium difficile infection
JP7283699B2 (ja) 2017-05-12 2023-05-30 マックス－プランク－ゲゼルシャフト・ツア・フェルデルング・デア・ヴィッセンシャフテン・エー・ファオ 黒色腫の治療または予防において使用するためのフェニル－ヘテロ環－フェニル誘導体
US10676467B2 (en) 2017-06-30 2020-06-09 Washington University Compositions for binding sphingosine-1-phosphate receptor 1 (S1P1), imaging of S1P1, and methods of use thereof
MA54460A (fr) 2018-12-14 2021-10-20 Eisai R&D Man Co Ltd Formulations pharmaceutiques à base d'eau de composés de 1,2-dihydropyridine
EP4403184A4 (en) 2021-09-15 2025-09-24 Univ Of The Ryukyus PHARMACEUTICAL COMPOSITION INTENDED FOR USE IN THE TREATMENT OF EITHER THE DECLINE OF COGNITIVE FUNCTIONS OR OVERWEIGHT OR OBESITY
JPWO2023042888A1 (no) 2021-09-15 2023-03-23
EP4173485A1 (en) 2021-10-27 2023-05-03 Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. Protein aggregation inhibiting compounds for plant disease control

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Also Published As

Publication number Publication date
IL129315A0 (en) 2000-02-17
KR20000049253A (ko) 2000-07-25
AU4867697A (en) 1998-05-15
PL332432A1 (en) 1999-09-13
TW413678B (en) 2000-12-01
NZ335598A (en) 2001-06-29
HUP0001652A2 (hu) 2001-01-29
CA2268954A1 (en) 1998-04-30
EP0934288A1 (de) 1999-08-11
AU737552B2 (en) 2001-08-23
BG103251A (bg) 2000-02-29
DE59712543D1 (de) 2006-03-30
CN1233245A (zh) 1999-10-27
CN1086698C (zh) 2002-06-26
AR008496A1 (es) 2000-01-19
RU2182905C2 (ru) 2002-05-27
PE11199A1 (es) 1999-03-03
HRP970553A2 (en) 1998-08-31
ID18613A (id) 1998-04-23
ATE315034T1 (de) 2006-02-15
BR9714354A (pt) 2000-04-11
HUP0001652A3 (en) 2002-12-28
JP3333523B2 (ja) 2002-10-15
JP2000505089A (ja) 2000-04-25
ZA979220B (en) 1998-04-20
HK1020956A1 (en) 2000-05-26
CZ138099A3 (cs) 1999-11-17
NO312512B1 (no) 2002-05-21
DE19643037A1 (de) 1998-04-23
EE9900147A (et) 1999-12-15
US6277872B1 (en) 2001-08-21
CO4920253A1 (es) 2000-05-29
EP0934288B1 (de) 2006-01-04
ES2256880T3 (es) 2006-07-16
CA2268954C (en) 2006-06-13
TR199900848T2 (xx) 1999-06-21
NO991815D0 (no) 1999-04-16
WO1998017652A1 (de) 1998-04-30
SK49999A3 (en) 1999-11-08
YU40997A (sh) 2000-10-30

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