DK0678088T3 - N-acylpyrrolidiner og lægemidler til behandling og forebyggelse af cholecystokinin- og gastrinrelaterede sygdomme - Google Patents

N-acylpyrrolidiner og lægemidler til behandling og forebyggelse af cholecystokinin- og gastrinrelaterede sygdomme

Info

Publication number: DK0678088T3
Authority: DK; Denmark
Prior art keywords: gastrin; pct; acylpyrrolidines; cholecystokinin; drugs
Prior art date: 1993-01-07

Application number

DK94903939.0T

Other languages

Danish (da)

English (en)

Inventor

Marc Capet

Marie-Christine Dubroeucq

Original Assignee

Rhone Poulenc Rorer Sa

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1993-01-07

Filing date

1994-01-03

Publication date

1996-11-18

1994-01-03 Application filed by Rhone Poulenc Rorer Sa filed Critical Rhone Poulenc Rorer Sa

1996-11-18 Application granted granted Critical

1996-11-18 Publication of DK0678088T3 publication Critical patent/DK0678088T3/da

Links

102100021022 Gastrin Human genes 0.000 title abstract 2
108010052343 Gastrins Proteins 0.000 title abstract 2
AOXOCDRNSPFDPE-UKEONUMOSA-N chembl413654 Chemical compound C([C@H](C(=O)NCC(=O)N[C@H](CC=1C2=CC=CC=C2NC=1)C(=O)N[C@H](CCSC)C(=O)N[C@H](CC(O)=O)C(=O)N[C@H](CC=1C=CC=CC=1)C(N)=O)NC(=O)[C@@H](C)NC(=O)[C@@H](CCC(O)=O)NC(=O)[C@@H](CCC(O)=O)NC(=O)[C@@H](CCC(O)=O)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC=1C2=CC=CC=C2NC=1)NC(=O)[C@H]1N(CCC1)C(=O)CNC(=O)[C@@H](N)CCC(O)=O)C1=CC=C(O)C=C1 AOXOCDRNSPFDPE-UKEONUMOSA-N 0.000 title abstract 2
238000011282 treatment Methods 0.000 title abstract 2
102100025841 Cholecystokinin Human genes 0.000 title 1
101800001982 Cholecystokinin Proteins 0.000 title 1
229940107137 cholecystokinin Drugs 0.000 title 1
201000010099 disease Diseases 0.000 title 1
208000037265 diseases, disorders, signs and symptoms Diseases 0.000 title 1
239000003814 drug Substances 0.000 title 1
229940079593 drug Drugs 0.000 title 1
230000002265 prevention Effects 0.000 title 1
IZTQOLKUZKXIRV-YRVFCXMDSA-N sincalide Chemical compound C([C@@H](C(=O)N[C@@H](CCSC)C(=O)NCC(=O)N[C@@H](CC=1C2=CC=CC=C2NC=1)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CC=1C=CC=CC=1)C(N)=O)NC(=O)[C@@H](N)CC(O)=O)C1=CC=C(OS(O)(=O)=O)C=C1 IZTQOLKUZKXIRV-YRVFCXMDSA-N 0.000 title 1
150000001875 compounds Chemical class 0.000 abstract 1
238000000034 method Methods 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D207/08—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon radicals, substituted by hetero atoms, attached to ring carbon atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D207/10—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D207/16—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/26—Psychostimulants, e.g. nicotine, cocaine
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Animal Behavior & Ethology (AREA)
Bioinformatics & Cheminformatics (AREA)
General Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Engineering & Computer Science (AREA)
Public Health (AREA)
Medicinal Chemistry (AREA)
Veterinary Medicine (AREA)
Pharmacology & Pharmacy (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Neurosurgery (AREA)
Neurology (AREA)
Biomedical Technology (AREA)
Psychiatry (AREA)
Pain & Pain Management (AREA)
Addiction (AREA)
Ophthalmology & Optometry (AREA)
Hospice & Palliative Care (AREA)
Anesthesiology (AREA)
Epidemiology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Pyrrole Compounds (AREA)
Peptides Or Proteins (AREA)
Plural Heterocyclic Compounds (AREA)

DK94903939.0T 1993-01-07 1994-01-03 N-acylpyrrolidiner og lægemidler til behandling og forebyggelse af cholecystokinin- og gastrinrelaterede sygdomme DK0678088T3 (da)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
FR9300077A FR2700165B1 (fr)	1993-01-07	1993-01-07	Dérivés de pyrrolidine, leur préparation et les médicaments les contenant.

Publications (1)

Publication Number	Publication Date
DK0678088T3 true DK0678088T3 (da)	1996-11-18

Family

ID=9442866

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK94903939.0T DK0678088T3 (da)	1993-01-07	1994-01-03	N-acylpyrrolidiner og lægemidler til behandling og forebyggelse af cholecystokinin- og gastrinrelaterede sygdomme

Country Status (19)

Country	Link
US (1)	US5624939A (de)
EP (1)	EP0678088B1 (de)
JP (1)	JPH08505614A (de)
KR (1)	KR960700228A (de)
AT (1)	ATE143946T1 (de)
AU (1)	AU5819294A (de)
CA (1)	CA2152281A1 (de)
DE (1)	DE69400702T2 (de)
DK (1)	DK0678088T3 (de)
ES (1)	ES2094048T3 (de)
FR (1)	FR2700165B1 (de)
GR (1)	GR3021313T3 (de)
HU (1)	HUT74095A (de)
IL (1)	IL108290A0 (de)
NO (1)	NO952559D0 (de)
NZ (1)	NZ259398A (de)
RU (1)	RU95116448A (de)
WO (1)	WO1994015914A1 (de)
ZA (1)	ZA9480B (de)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
FR2721608B1 (fr) *	1994-06-22	1996-07-19	Rhone Poulenc Rorer Sa	Dérivés de thiazolidine, leur préparation et les médicaments les contenant.
FR2744362B1 (fr) *	1996-02-07	1998-02-27	Rhone Poulenc Rorer Sa	Application de derives de pyrrolidine a la preparation de medicaments destines au traitement de l'abus de drogues ou de substances donnant lieu a des pharmacomanies ou a un usage excessif
FR2744361B1 (fr) *	1996-02-07	1998-02-27	Rhone Poulenc Rorer Sa	Application de derives de pyrrolidine a la preparation de medicaments destines au traitement de l'abus de drogues ou de substances donnant lieu a des pharmacomanies ou a un usage excessif
TW442449B (en)	1996-07-04	2001-06-23	Hoechst Ag	Process for preparing 1,2-dichloroethane by direct chlorination
US6737409B2 (en) *	2001-07-19	2004-05-18	Hoffmann-La Roche Inc.	Dolastatin 10 derivatives
DE10218377B4 (de) *	2002-04-25	2004-03-11	Rea Gesellschaft Für Recycling Von Energie Und Abfall Mbh	Verfahren und Vorrichtung zur Schwerstoffabtrennung aus Aufschlämmungen
US8247438B2 (en)	2008-02-27	2012-08-21	Neuropill, Inc.	Methods for treating schizophrenia

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
EP0124317B1 (de) *	1983-04-27	1990-04-11	Ici Americas Inc.	Prolin-Derivate
FR2667864B2 (fr) *	1990-03-07	1994-08-05	Rhone Poulenc Sante	Derives de n-phenyl glycinamides, leur preparation et les medicaments les contenant.
FR2678938B1 (fr) *	1991-07-10	1993-10-08	Rhone Poulenc Rorer Sa	Derives de pyrrolidine, leur preparation et les medicaments les contenant.

1993
- 1993-01-07 FR FR9300077A patent/FR2700165B1/fr not_active Expired - Fee Related
1994
- 1994-01-03 AT AT94903939T patent/ATE143946T1/de not_active IP Right Cessation
- 1994-01-03 AU AU58192/94A patent/AU5819294A/en not_active Abandoned
- 1994-01-03 CA CA002152281A patent/CA2152281A1/fr not_active Abandoned
- 1994-01-03 EP EP94903939A patent/EP0678088B1/de not_active Expired - Lifetime
- 1994-01-03 JP JP6515747A patent/JPH08505614A/ja active Pending
- 1994-01-03 DE DE69400702T patent/DE69400702T2/de not_active Expired - Fee Related
- 1994-01-03 KR KR1019950702823A patent/KR960700228A/ko not_active Withdrawn
- 1994-01-03 ES ES94903939T patent/ES2094048T3/es not_active Expired - Lifetime
- 1994-01-03 RU RU95116448/04A patent/RU95116448A/ru unknown
- 1994-01-03 US US08/448,406 patent/US5624939A/en not_active Expired - Fee Related
- 1994-01-03 DK DK94903939.0T patent/DK0678088T3/da active
- 1994-01-03 WO PCT/FR1994/000008 patent/WO1994015914A1/fr not_active Ceased
- 1994-01-03 HU HU9502067A patent/HUT74095A/hu unknown
- 1994-01-03 NZ NZ259398A patent/NZ259398A/en unknown
- 1994-01-06 IL IL10829094A patent/IL108290A0/xx unknown
- 1994-01-06 ZA ZA9480A patent/ZA9480B/xx unknown
1995
- 1995-06-26 NO NO952559A patent/NO952559D0/no unknown
1996
- 1996-10-10 GR GR960401619T patent/GR3021313T3/el unknown

Also Published As

Publication number	Publication date
FR2700165A1 (fr)	1994-07-08
EP0678088A1 (de)	1995-10-25
KR960700228A (ko)	1996-01-19
FR2700165B1 (fr)	1995-02-17
HU9502067D0 (en)	1995-09-28
CA2152281A1 (fr)	1994-07-21
AU5819294A (en)	1994-08-15
ATE143946T1 (de)	1996-10-15
ES2094048T3 (es)	1997-01-01
DE69400702T2 (de)	1997-03-06
GR3021313T3 (en)	1997-01-31
US5624939A (en)	1997-04-29
WO1994015914A1 (fr)	1994-07-21
RU95116448A (ru)	1997-06-10
EP0678088B1 (de)	1996-10-09
NZ259398A (en)	1996-02-27
DE69400702D1 (de)	1996-11-14
ZA9480B (en)	1994-08-11
NO952559L (no)	1995-06-26
HUT74095A (en)	1996-11-28
JPH08505614A (ja)	1996-06-18
IL108290A0 (en)	1994-04-12
NO952559D0 (no)	1995-06-26

Publication	Publication Date	Title
DE59409312D1 (de)	2000-05-31	Imidazopyridine und ihre anwendung zur behandlung von magen-darm krankheiten
FI932229A0 (fi)	1993-05-17	Azabicykliska bryggderivat
NO960365D0 (no)	1996-01-29	Perhydroisoindolderivater som substans-P-antagonister
AU2672995A (en)	1995-12-21	{a}-annelated pyrrole derivatives and pharmaceutical uses thereof
NO961414L (no)	1996-06-10	Alkoksyalkylkarbamater av imidazo (1,2-a)pyridiner
DK0752854T3 (da)	2001-10-08	Pyrimidin- eller triazincarboxylsyrederivater til anvendelse som lægemiddel
DK0748314T3 (da)	2002-08-26	Tetrasubstituerede imidazolderivater, fremgangsmåde til deres fremstilling, deres anvendelse som lægemidler og farmaceutiske præparater med indhold deraf
DE69511544D1 (de)	1999-09-23	Amidderivate und ihre therapeutische verwendung
DK0711283T3 (da)	1999-11-22	Tetrahydro-1H-benzazepinoner og hexahydroazepinoner som selektive cholecystokinin-B-receptorantagonister
DK0678088T3 (da)	1996-11-18	N-acylpyrrolidiner og lægemidler til behandling og forebyggelse af cholecystokinin- og gastrinrelaterede sygdomme
SE8701375D0 (sv)	1987-04-02	Novel pyridyl- and pyrimidyl derivatives
DK0678089T3 (da)	1996-11-18	N-Acylpyrrolidiner og lægemidler til behandling eller forebyggelse af cholecystokinin- og gastrin-relaterede forstyrrelser
ES2094545T3 (es)	1997-01-16	Derivados n-substituidos del 3-azabiciclo(3.2.0)heptano, como neurolepticos etc..
NZ320522A (en)	1999-03-29	Piperazinylalkylthiopyrimidine derivatives, pharmaceutical compositions containing the same and a process for the preparation of the compounds
DK0737187T3 (da)	1999-11-15	Benzoxazinderivater, fremgangsmåder til fremstilling deraf og deres anvendelse som lægemidler
DK0766695T3 (da)	1999-02-15	Pyrrolidinderivater til behandling af CCK- og gastrinrelaterede sygdomme
DK0729469T3 (da)	1999-06-14	Imidazo[1,5-a]quinoliner til behandling af angst og søvnforstyrrelser
MX9306879A (es)	1995-01-31	Derivados de piperazina y composiciones farmaceuticas que los contienen,para el tratamiento de enfermedades del conocimiento.