DK0679161T3 - Thiazolidinderivater, fremstilling af disse derivater og lægemidler indeholdende disse derivater - Google Patents

Thiazolidinderivater, fremstilling af disse derivater og lægemidler indeholdende disse derivater

Info

Publication number: DK0679161T3
Authority: DK; Denmark
Prior art keywords: derivatives; pct; preparation; drugs containing; thiazolidine
Prior art date: 1993-01-07

Application number

DK94904199T

Other languages

English (en)

Inventor

Marie-Christine Dubroeucq

Franco Manfre

Original Assignee

Rhone Poulenc Rorer Sa

Aventis Pharma Sa

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1993-01-07

Filing date

1994-01-03

Publication date

1999-02-01

1994-01-03 Application filed by Rhone Poulenc Rorer Sa, Aventis Pharma Sa filed Critical Rhone Poulenc Rorer Sa

1999-02-01 Application granted granted Critical

1999-02-01 Publication of DK0679161T3 publication Critical patent/DK0679161T3/da

Links

239000003814 drug Substances 0.000 title abstract 2
229940079593 drug Drugs 0.000 title abstract 2
150000003548 thiazolidines Chemical class 0.000 title 1
102100025841 Cholecystokinin Human genes 0.000 abstract 3
101800001982 Cholecystokinin Proteins 0.000 abstract 3
229940107137 cholecystokinin Drugs 0.000 abstract 3
IZTQOLKUZKXIRV-YRVFCXMDSA-N sincalide Chemical compound C([C@@H](C(=O)N[C@@H](CCSC)C(=O)NCC(=O)N[C@@H](CC=1C2=CC=CC=C2NC=1)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CC=1C=CC=CC=1)C(N)=O)NC(=O)[C@@H](N)CC(O)=O)C1=CC=C(OS(O)(=O)=O)C=C1 IZTQOLKUZKXIRV-YRVFCXMDSA-N 0.000 abstract 3
150000001875 compounds Chemical class 0.000 abstract 2
108010089448 Cholecystokinin B Receptor Proteins 0.000 abstract 1
102100021022 Gastrin Human genes 0.000 abstract 1
102000052874 Gastrin receptors Human genes 0.000 abstract 1
108010052343 Gastrins Proteins 0.000 abstract 1
AOXOCDRNSPFDPE-UKEONUMOSA-N chembl413654 Chemical compound C([C@H](C(=O)NCC(=O)N[C@H](CC=1C2=CC=CC=C2NC=1)C(=O)N[C@H](CCSC)C(=O)N[C@H](CC(O)=O)C(=O)N[C@H](CC=1C=CC=CC=1)C(N)=O)NC(=O)[C@@H](C)NC(=O)[C@@H](CCC(O)=O)NC(=O)[C@@H](CCC(O)=O)NC(=O)[C@@H](CCC(O)=O)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC=1C2=CC=CC=C2NC=1)NC(=O)[C@H]1N(CCC1)C(=O)CNC(=O)[C@@H](N)CCC(O)=O)C1=CC=C(O)C=C1 AOXOCDRNSPFDPE-UKEONUMOSA-N 0.000 abstract 1
210000001035 gastrointestinal tract Anatomy 0.000 abstract 1
210000000653 nervous system Anatomy 0.000 abstract 1
230000000144 pharmacologic effect Effects 0.000 abstract 1
230000002265 prevention Effects 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
- C07K5/06008—Dipeptides with the first amino acid being neutral
- C07K5/06017—Dipeptides with the first amino acid being neutral and aliphatic
- C07K5/06026—Dipeptides with the first amino acid being neutral and aliphatic the side chain containing 0 or 1 carbon atom, i.e. Gly or Ala
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/26—Psychostimulants, e.g. nicotine, cocaine
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/04—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
- C07D277/06—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Veterinary Medicine (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Public Health (AREA)
Animal Behavior & Ethology (AREA)
Pharmacology & Pharmacy (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Biochemistry (AREA)
Molecular Biology (AREA)
Genetics & Genomics (AREA)
Biophysics (AREA)
Pain & Pain Management (AREA)
Psychiatry (AREA)
Immunology (AREA)
Child & Adolescent Psychology (AREA)
Diabetes (AREA)
Hematology (AREA)
Obesity (AREA)
Anesthesiology (AREA)
Epidemiology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Thiazole And Isothizaole Compounds (AREA)
Pyrrole Compounds (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Peptides Or Proteins (AREA)

DK94904199T 1993-01-07 1994-01-03 Thiazolidinderivater, fremstilling af disse derivater og lægemidler indeholdende disse derivater DK0679161T3 (da)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
FR9300076A FR2700168B1 (fr)	1993-01-07	1993-01-07	Dérivés de thiazolidine, leur préparation et les médicaments les contenant.
PCT/FR1994/000007 WO1994015955A1 (fr)	1993-01-07	1994-01-03	Derives de thiazolidine, leur preparation et les medicaments les contenant

Publications (1)

Publication Number	Publication Date
DK0679161T3 true DK0679161T3 (da)	1999-02-01

Family

ID=9442864

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK94904199T DK0679161T3 (da)	1993-01-07	1994-01-03	Thiazolidinderivater, fremstilling af disse derivater og lægemidler indeholdende disse derivater

Country Status (17)

Country	Link
US (1)	US5633270A (da)
EP (1)	EP0679161B1 (da)
JP (1)	JPH08507292A (da)
KR (1)	KR960700268A (da)
AT (1)	ATE167681T1 (da)
AU (1)	AU5835194A (da)
CA (1)	CA2152184A1 (da)
DE (1)	DE69411260T2 (da)
DK (1)	DK0679161T3 (da)
ES (1)	ES2119160T3 (da)
FR (1)	FR2700168B1 (da)
HU (1)	HUT73428A (da)
IL (1)	IL108289A0 (da)
NO (1)	NO952687L (da)
NZ (1)	NZ259530A (da)
WO (1)	WO1994015955A1 (da)
ZA (1)	ZA9479B (da)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
FR2721608B1 (fr) *	1994-06-22	1996-07-19	Rhone Poulenc Rorer Sa	Dérivés de thiazolidine, leur préparation et les médicaments les contenant.
FR2744361B1 (fr) *	1996-02-07	1998-02-27	Rhone Poulenc Rorer Sa	Application de derives de pyrrolidine a la preparation de medicaments destines au traitement de l'abus de drogues ou de substances donnant lieu a des pharmacomanies ou a un usage excessif
FR2744362B1 (fr) *	1996-02-07	1998-02-27	Rhone Poulenc Rorer Sa	Application de derives de pyrrolidine a la preparation de medicaments destines au traitement de l'abus de drogues ou de substances donnant lieu a des pharmacomanies ou a un usage excessif
FR2744363B1 (fr) *	1996-02-07	1998-02-27	Rhone Poulenc Rorer Sa	Application de derives de thiazolidine a la preparation de medicaments destines au traitement de l'abus de drogues ou de substances donnant lieu a des pharmacomanies ou a un usage excessif
TW442449B (en)	1996-07-04	2001-06-23	Hoechst Ag	Process for preparing 1,2-dichloroethane by direct chlorination
DE69820614T2 (de) *	1997-05-30	2004-09-30	Celltech Therapeutics Ltd., Slough	Entzündungshemmende tyrosin-derivate
GB9713087D0 (en) *	1997-06-20	1997-08-27	Celltech Therapeutics Ltd	Chemical compounds
US6329372B1 (en)	1998-01-27	2001-12-11	Celltech Therapeutics Limited	Phenylalanine derivatives
ATE273273T1 (de)	1998-02-26	2004-08-15	Celltech Therapeutics Ltd	Phenylalaninderivate als inhibitoren von alpha4 integrinen
GB9805655D0 (en)	1998-03-16	1998-05-13	Celltech Therapeutics Ltd	Chemical compounds
US6521626B1 (en)	1998-03-24	2003-02-18	Celltech R&D Limited	Thiocarboxamide derivatives
GB9811159D0 (en)	1998-05-22	1998-07-22	Celltech Therapeutics Ltd	Chemical compounds
GB9811969D0 (en) *	1998-06-03	1998-07-29	Celltech Therapeutics Ltd	Chemical compounds
GB9814414D0 (en)	1998-07-03	1998-09-02	Celltech Therapeutics Ltd	Chemical compounds
GB9821061D0 (en)	1998-09-28	1998-11-18	Celltech Therapeutics Ltd	Chemical compounds
GB9821222D0 (en)	1998-09-30	1998-11-25	Celltech Therapeutics Ltd	Chemical compounds
GB9825652D0 (en)	1998-11-23	1999-01-13	Celltech Therapeutics Ltd	Chemical compounds
GB9826174D0 (en)	1998-11-30	1999-01-20	Celltech Therapeutics Ltd	Chemical compounds
US6518283B1 (en)	1999-05-28	2003-02-11	Celltech R&D Limited	Squaric acid derivatives
US6534513B1 (en)	1999-09-29	2003-03-18	Celltech R&D Limited	Phenylalkanoic acid derivatives
US6455539B2 (en)	1999-12-23	2002-09-24	Celltech R&D Limited	Squaric acid derivates
DE60130910T2 (de)	2000-04-17	2008-07-10	Ucb Pharma, S.A.	Enamin-derivate als zell-adhäsionsmoleküle
US6545013B2 (en)	2000-05-30	2003-04-08	Celltech R&D Limited	2,7-naphthyridine derivatives
US6403608B1 (en)	2000-05-30	2002-06-11	Celltech R&D, Ltd.	3-Substituted isoquinolin-1-yl derivatives
JP2004502762A (ja)	2000-07-07	2004-01-29	セルテック　アール　アンド　ディ　リミテッド	二環性ヘテロ芳香環を含有するインテグリンアンタゴニストとしてのスクエア酸誘導体
JP2004505110A (ja)	2000-08-02	2004-02-19	セルテック　アール　アンド　ディ　リミテッド	３位置換イソキノリン−１−イル誘導体
AU2003291227A1 (en)	2002-11-05	2004-06-07	Smithkline Beecham Corporation	Antibacterial agents
BRPI0507612A (pt) *	2004-02-11	2007-07-03	Univ Ohio State Res Found	análogos exibindo inibição de proliferação de célula e métodos para fabricação e uso destes
US8247438B2 (en)	2008-02-27	2012-08-21	Neuropill, Inc.	Methods for treating schizophrenia

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
FR2659653B1 (fr) *	1990-03-13	1992-05-22	Rhone Poulenc Sante	Derives de l'uree, leur preparation et les medicaments les contenant.
FR2678938B1 (fr) *	1991-07-10	1993-10-08	Rhone Poulenc Rorer Sa	Derives de pyrrolidine, leur preparation et les medicaments les contenant.

1993
- 1993-01-07 FR FR9300076A patent/FR2700168B1/fr not_active Expired - Fee Related
1994
- 1994-01-03 ES ES94904199T patent/ES2119160T3/es not_active Expired - Lifetime
- 1994-01-03 NZ NZ259530A patent/NZ259530A/en unknown
- 1994-01-03 WO PCT/FR1994/000007 patent/WO1994015955A1/fr not_active Ceased
- 1994-01-03 DE DE69411260T patent/DE69411260T2/de not_active Expired - Fee Related
- 1994-01-03 CA CA002152184A patent/CA2152184A1/fr not_active Abandoned
- 1994-01-03 DK DK94904199T patent/DK0679161T3/da active
- 1994-01-03 AT AT94904199T patent/ATE167681T1/de not_active IP Right Cessation
- 1994-01-03 HU HU9502064A patent/HUT73428A/hu unknown
- 1994-01-03 JP JP6515746A patent/JPH08507292A/ja active Pending
- 1994-01-03 US US08/446,745 patent/US5633270A/en not_active Expired - Fee Related
- 1994-01-03 EP EP94904199A patent/EP0679161B1/fr not_active Expired - Lifetime
- 1994-01-03 AU AU58351/94A patent/AU5835194A/en not_active Abandoned
- 1994-01-03 KR KR1019950702796A patent/KR960700268A/ko not_active Withdrawn
- 1994-01-06 ZA ZA9479A patent/ZA9479B/xx unknown
- 1994-01-06 IL IL10828994A patent/IL108289A0/xx unknown
1995
- 1995-07-06 NO NO952687A patent/NO952687L/no unknown

Also Published As

Publication number	Publication date
FR2700168A1 (fr)	1994-07-08
NO952687L (no)	1995-09-05
NZ259530A (en)	1996-06-25
ZA9479B (en)	1994-08-11
CA2152184A1 (fr)	1994-07-21
EP0679161B1 (fr)	1998-06-24
WO1994015955A1 (fr)	1994-07-21
ES2119160T3 (es)	1998-10-01
NO952687D0 (no)	1995-07-06
HU9502064D0 (en)	1995-09-28
DE69411260D1 (de)	1998-07-30
DE69411260T2 (de)	1999-01-07
ATE167681T1 (de)	1998-07-15
KR960700268A (ko)	1996-01-19
FR2700168B1 (fr)	1995-02-03
AU5835194A (en)	1994-08-15
JPH08507292A (ja)	1996-08-06
IL108289A0 (en)	1994-04-12
HUT73428A (en)	1996-07-29
US5633270A (en)	1997-05-27
EP0679161A1 (fr)	1995-11-02

Publication	Publication Date	Title
HU9502064D0 (en)	1995-09-28	Thiazolidine derivatives, preparation thereof and drugs containing same
DE69229674D1 (de)	1999-09-02	5-ht4 rezeptor antagonisten
DK0561941T3 (da)	1995-03-06	N-Substituerede lactamer anvendelige som cholecystokinin-antagonister
DK0583485T3 (da)	1997-10-06	Ethanolaminderivater med sympathomimetiske og anti-pollakisuria-virkninger
ATE222587T1 (de)	2002-09-15	TROPAN-2-ALDOXIMDERIVATE ALS NEUROTRANSMITTER ßREUPTAKEß INHIBITOREN
DK0572635T3 (da)	1997-06-16	Hidtil ukendte forbindelser med guanidinstruktur og farmaceutisk komposition indeholdende forbindelserne
PL316870A1 (en)	1997-02-17	Derivatives of 5-heterocyclo 1,5-benzodiazepine
SE8701375D0 (sv)	1987-04-02	Novel pyridyl- and pyrimidyl derivatives
DK0678089T3 (da)	1996-11-18	N-Acylpyrrolidiner og lægemidler til behandling eller forebyggelse af cholecystokinin- og gastrin-relaterede forstyrrelser
DK0678088T3 (da)	1996-11-18	N-acylpyrrolidiner og lægemidler til behandling og forebyggelse af cholecystokinin- og gastrinrelaterede sygdomme
DK0625982T3 (da)	2002-09-30	4-Oxo- og 4H-imidazo(5,1-c)(1,4)benzoxaziner anvendelige som benzodiazepinreceptor-bindemidler