DK0683170T3 - Glucopyranosidbenzothiophener - Google Patents

Glucopyranosidbenzothiophener

Info

Publication number
DK0683170T3
DK0683170T3 DK95303265T DK95303265T DK0683170T3 DK 0683170 T3 DK0683170 T3 DK 0683170T3 DK 95303265 T DK95303265 T DK 95303265T DK 95303265 T DK95303265 T DK 95303265T DK 0683170 T3 DK0683170 T3 DK 0683170T3
Authority
DK
Denmark
Prior art keywords
benzothiophenes
glucopyranoside
chem
solvate
processes
Prior art date
Application number
DK95303265T
Other languages
English (en)
Inventor
Jeffrey Alan Dodge
Charles Alan Frolik
Terry Donald Lindstrom
Charles Willis Lugar Iii
Gilbert Stanley Staten
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Application granted granted Critical
Publication of DK0683170T3 publication Critical patent/DK0683170T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/26—Acyclic or carbocyclic radicals, substituted by hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/10—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Diabetes (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Steroid Compounds (AREA)
  • Networks Using Active Elements (AREA)
  • Photoreceptors In Electrophotography (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
DK95303265T 1994-05-20 1995-05-16 Glucopyranosidbenzothiophener DK0683170T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US24665594A 1994-05-20 1994-05-20

Publications (1)

Publication Number Publication Date
DK0683170T3 true DK0683170T3 (da) 1999-12-20

Family

ID=22931623

Family Applications (1)

Application Number Title Priority Date Filing Date
DK95303265T DK0683170T3 (da) 1994-05-20 1995-05-16 Glucopyranosidbenzothiophener

Country Status (27)

Country Link
US (2) US6723739B1 (da)
EP (1) EP0683170B1 (da)
JP (1) JPH07316180A (da)
KR (1) KR950032183A (da)
CN (1) CN1039013C (da)
AT (1) ATE184880T1 (da)
AU (1) AU683734B2 (da)
BR (1) BR9502079A (da)
CA (1) CA2149501A1 (da)
CO (1) CO4650137A1 (da)
CZ (1) CZ126295A3 (da)
DE (1) DE69512310T2 (da)
DK (1) DK0683170T3 (da)
ES (1) ES2136799T3 (da)
FI (1) FI952420L (da)
GR (1) GR3032142T3 (da)
HU (1) HU219335B (da)
IL (1) IL113780A (da)
NO (1) NO304694B1 (da)
NZ (1) NZ272131A (da)
PE (1) PE23396A1 (da)
PL (1) PL308635A1 (da)
RU (1) RU95107655A (da)
SI (1) SI0683170T1 (da)
TW (1) TW323285B (da)
YU (1) YU31995A (da)
ZA (1) ZA953975B (da)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HUP9801829A3 (en) * 1995-02-06 1999-10-28 Lilly Co Eli Use of benzotiophene derivatives for producing pharmaceutical compositions for inhibiting effects of il-6
US20040167080A1 (en) * 1995-03-15 2004-08-26 Dodge Jeffrey A. Glucopyranoside benzothiophenes
US6458811B1 (en) 1996-03-26 2002-10-01 Eli Lilly And Company Benzothiophenes formulations containing same and methods
BR9708248A (pt) * 1996-03-26 1999-07-27 Lilly Co Eli Benzotiofenos formulações contendo os mesmos e metódos
ES2246234T3 (es) 1999-05-04 2006-02-16 Strakan International Limited Glicosidos de androgenos y actividad androgenica de los mismos.
US6380166B1 (en) 1999-09-13 2002-04-30 American Home Products Corporation Glucopyranosides conjugates of 2-(4-hydroxy-phenyl)-3-methyl-1-[4-(2-amin-1-yl-ethoxy)-benzyl]-1H-indol-5-ols
HK1044777B (en) * 1999-09-13 2006-04-13 Wyeth Glucopyranosides conjugates of 2-(4-hydroxy-phenyl)-1-[4-(2-amin-1-yl-ethoxy)-benzyl]-1h-indol-5-ols
AU7673900A (en) * 1999-10-08 2001-04-23 Strakan Limited Glycosides and orthoester glycosides of raloxifene and analogues and the use thereof
AU7674000A (en) * 1999-10-08 2001-04-23 Strakan Group Plc Tamoxifen and tamoxifen analogue glycosides and uses thereof
WO2011029088A2 (en) * 2009-09-07 2011-03-10 Dr. Reddy's Laboratories Ltd. Preparation of raloxifene and its salts

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4133814A (en) 1975-10-28 1979-01-09 Eli Lilly And Company 2-Phenyl-3-aroylbenzothiophenes useful as antifertility agents
US4418068A (en) 1981-04-03 1983-11-29 Eli Lilly And Company Antiestrogenic and antiandrugenic benzothiophenes
TW366342B (en) * 1992-07-28 1999-08-11 Lilly Co Eli The use of 2-phenyl-3-aroylbenzothiophenes in inhibiting bone loss

Also Published As

Publication number Publication date
CN1039013C (zh) 1998-07-08
YU31995A (sh) 1998-12-23
HU219335B (en) 2001-03-28
NO951954L (no) 1995-11-21
JPH07316180A (ja) 1995-12-05
DE69512310T2 (de) 2000-02-03
NO951954D0 (no) 1995-05-18
US6723739B1 (en) 2004-04-20
RU95107655A (ru) 1997-02-10
NZ272131A (en) 1996-11-26
IL113780A (en) 1999-06-20
KR950032183A (ko) 1995-12-20
US5567820A (en) 1996-10-22
NO304694B1 (no) 1999-02-01
SI0683170T1 (en) 2000-02-29
HU9501466D0 (en) 1995-06-28
PE23396A1 (es) 1996-06-15
FI952420A7 (fi) 1995-11-21
GR3032142T3 (en) 2000-04-27
TW323285B (da) 1997-12-21
HUT73788A (en) 1996-09-30
IL113780A0 (en) 1995-08-31
CN1116626A (zh) 1996-02-14
DE69512310D1 (de) 1999-10-28
CA2149501A1 (en) 1995-11-21
ATE184880T1 (de) 1999-10-15
ZA953975B (en) 1996-11-18
CO4650137A1 (es) 1998-09-03
BR9502079A (pt) 1996-03-05
FI952420A0 (fi) 1995-05-18
EP0683170A1 (en) 1995-11-22
ES2136799T3 (es) 1999-12-01
CZ126295A3 (en) 1995-12-13
PL308635A1 (en) 1995-11-27
EP0683170B1 (en) 1999-09-22
AU683734B2 (en) 1997-11-20
AU2012195A (en) 1995-11-30
FI952420L (fi) 1995-11-21

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