GR3032142T3 - Glucopyranoside benzothiophenes. - Google Patents

Glucopyranoside benzothiophenes.

Info

Publication number
GR3032142T3
GR3032142T3 GR990403228T GR990403228T GR3032142T3 GR 3032142 T3 GR3032142 T3 GR 3032142T3 GR 990403228 T GR990403228 T GR 990403228T GR 990403228 T GR990403228 T GR 990403228T GR 3032142 T3 GR3032142 T3 GR 3032142T3
Authority
GR
Greece
Prior art keywords
benzothiophenes
glucopyranoside
chem
solvate
processes
Prior art date
Application number
GR990403228T
Other languages
English (en)
Inventor
Jeffrey Alan Dodge
Charles Alan Frolik
Terry Donald Lindstrom
Charles Willis Lugar Iii
Gilbert Stanley Staten
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of GR3032142T3 publication Critical patent/GR3032142T3/el

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/26—Acyclic or carbocyclic radicals, substituted by hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/10—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Diabetes (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Steroid Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Networks Using Active Elements (AREA)
  • Photoreceptors In Electrophotography (AREA)
GR990403228T 1994-05-20 1999-12-15 Glucopyranoside benzothiophenes. GR3032142T3 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US24665594A 1994-05-20 1994-05-20

Publications (1)

Publication Number Publication Date
GR3032142T3 true GR3032142T3 (en) 2000-04-27

Family

ID=22931623

Family Applications (1)

Application Number Title Priority Date Filing Date
GR990403228T GR3032142T3 (en) 1994-05-20 1999-12-15 Glucopyranoside benzothiophenes.

Country Status (27)

Country Link
US (2) US5567820A (el)
EP (1) EP0683170B1 (el)
JP (1) JPH07316180A (el)
KR (1) KR950032183A (el)
CN (1) CN1039013C (el)
AT (1) ATE184880T1 (el)
AU (1) AU683734B2 (el)
BR (1) BR9502079A (el)
CA (1) CA2149501A1 (el)
CO (1) CO4650137A1 (el)
CZ (1) CZ126295A3 (el)
DE (1) DE69512310T2 (el)
DK (1) DK0683170T3 (el)
ES (1) ES2136799T3 (el)
FI (1) FI952420A7 (el)
GR (1) GR3032142T3 (el)
HU (1) HU219335B (el)
IL (1) IL113780A (el)
NO (1) NO304694B1 (el)
NZ (1) NZ272131A (el)
PE (1) PE23396A1 (el)
PL (1) PL308635A1 (el)
RU (1) RU95107655A (el)
SI (1) SI0683170T1 (el)
TW (1) TW323285B (el)
YU (1) YU31995A (el)
ZA (1) ZA953975B (el)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HUP9801829A3 (en) * 1995-02-06 1999-10-28 Lilly Co Eli Use of benzotiophene derivatives for producing pharmaceutical compositions for inhibiting effects of il-6
US20040167080A1 (en) * 1995-03-15 2004-08-26 Dodge Jeffrey A. Glucopyranoside benzothiophenes
US6458811B1 (en) 1996-03-26 2002-10-01 Eli Lilly And Company Benzothiophenes formulations containing same and methods
EA001257B1 (ru) * 1996-03-26 2000-12-25 Эли Лилли Энд Компани Бензотиофены, содержащие их фармацевтические композиции и способы лечения патологических состояний с их использованием
CN1250563C (zh) 1999-05-04 2006-04-12 斯特拉坎有限公司 雄激素糖苷及其产生雄性征的活性
CA2382683A1 (en) * 1999-09-13 2001-03-22 American Home Products Corporation Glucopyranosides conjugates of 2-(4-hydroxy-phenyl)-1-¬4-(2-amin-1-yl-ethoxy)-benzyl|-1h-indol-5-ols
US6380166B1 (en) 1999-09-13 2002-04-30 American Home Products Corporation Glucopyranosides conjugates of 2-(4-hydroxy-phenyl)-3-methyl-1-[4-(2-amin-1-yl-ethoxy)-benzyl]-1H-indol-5-ols
AU7674000A (en) * 1999-10-08 2001-04-23 Strakan Group Plc Tamoxifen and tamoxifen analogue glycosides and uses thereof
WO2001027129A1 (en) * 1999-10-08 2001-04-19 Strakan Limited Glycosides and orthoester glycosides of raloxifene and analogues and the use thereof
WO2011029088A2 (en) * 2009-09-07 2011-03-10 Dr. Reddy's Laboratories Ltd. Preparation of raloxifene and its salts

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4133814A (en) 1975-10-28 1979-01-09 Eli Lilly And Company 2-Phenyl-3-aroylbenzothiophenes useful as antifertility agents
US4418068A (en) 1981-04-03 1983-11-29 Eli Lilly And Company Antiestrogenic and antiandrugenic benzothiophenes
TW366342B (en) * 1992-07-28 1999-08-11 Lilly Co Eli The use of 2-phenyl-3-aroylbenzothiophenes in inhibiting bone loss

Also Published As

Publication number Publication date
DE69512310T2 (de) 2000-02-03
CA2149501A1 (en) 1995-11-21
NO304694B1 (no) 1999-02-01
FI952420L (fi) 1995-11-21
FI952420A7 (fi) 1995-11-21
NO951954D0 (no) 1995-05-18
FI952420A0 (fi) 1995-05-18
NZ272131A (en) 1996-11-26
EP0683170B1 (en) 1999-09-22
CN1116626A (zh) 1996-02-14
SI0683170T1 (en) 2000-02-29
HU9501466D0 (en) 1995-06-28
HU219335B (en) 2001-03-28
CZ126295A3 (en) 1995-12-13
AU683734B2 (en) 1997-11-20
US5567820A (en) 1996-10-22
JPH07316180A (ja) 1995-12-05
TW323285B (el) 1997-12-21
IL113780A0 (en) 1995-08-31
RU95107655A (ru) 1997-02-10
CN1039013C (zh) 1998-07-08
ATE184880T1 (de) 1999-10-15
NO951954L (no) 1995-11-21
PE23396A1 (es) 1996-06-15
BR9502079A (pt) 1996-03-05
US6723739B1 (en) 2004-04-20
YU31995A (sh) 1998-12-23
IL113780A (en) 1999-06-20
ZA953975B (en) 1996-11-18
EP0683170A1 (en) 1995-11-22
CO4650137A1 (es) 1998-09-03
ES2136799T3 (es) 1999-12-01
AU2012195A (en) 1995-11-30
PL308635A1 (en) 1995-11-27
KR950032183A (ko) 1995-12-20
DK0683170T3 (da) 1999-12-20
HUT73788A (en) 1996-09-30
DE69512310D1 (de) 1999-10-28

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