DK0687256T3 - Hydroxymethylfurazancarboxylsyrederivater og deresanvendelse ved behandling af kardiovaskulære sygdomme - Google Patents

Hydroxymethylfurazancarboxylsyrederivater og deresanvendelse ved behandling af kardiovaskulære sygdomme

Info

Publication number: DK0687256T3
Authority: DK; Denmark
Prior art keywords: hydroxymethyl; acid derivatives; treatment; cardiovascular diseases; furazanecarboxylic
Prior art date: 1993-03-06

Application number

DK94908337.2T

Other languages

English (en)

Inventor

Karl Schoenafinger

Helmut Bohn

Original Assignee

Hoechst Ag

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1993-03-06

Filing date

1994-02-18

Publication date

1998-03-30

1994-02-18 Application filed by Hoechst Ag filed Critical Hoechst Ag

1998-03-30 Application granted granted Critical

1998-03-30 Publication of DK0687256T3 publication Critical patent/DK0687256T3/da

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D271/00—Heterocyclic compounds containing five-membered rings having two nitrogen atoms and one oxygen atom as the only ring hetero atoms
- C07D271/02—Heterocyclic compounds containing five-membered rings having two nitrogen atoms and one oxygen atom as the only ring hetero atoms not condensed with other rings
- C07D271/04—1,2,3-Oxadiazoles; Hydrogenated 1,2,3-oxadiazoles
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/10—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing aromatic rings
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/10—Drugs for genital or sexual disorders; Contraceptives for impotence
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D271/00—Heterocyclic compounds containing five-membered rings having two nitrogen atoms and one oxygen atom as the only ring hetero atoms
- C07D271/02—Heterocyclic compounds containing five-membered rings having two nitrogen atoms and one oxygen atom as the only ring hetero atoms not condensed with other rings
- C07D271/08—1,2,5-Oxadiazoles; Hydrogenated 1,2,5-oxadiazoles

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
General Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
Cardiology (AREA)
Heart & Thoracic Surgery (AREA)
Endocrinology (AREA)
Reproductive Health (AREA)
Urology & Nephrology (AREA)
Gynecology & Obstetrics (AREA)
Diabetes (AREA)
Vascular Medicine (AREA)
Hematology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Agricultural Chemicals And Associated Chemicals (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

DK94908337.2T 1993-03-06 1994-02-18 Hydroxymethylfurazancarboxylsyrederivater og deresanvendelse ved behandling af kardiovaskulære sygdomme DK0687256T3 (da)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
DE4307105A DE4307105A1 (de)	1993-03-06	1993-03-06	Hydroxymethylfurazancarbonsäurederivate

Publications (1)

Publication Number	Publication Date
DK0687256T3 true DK0687256T3 (da)	1998-03-30

Family

ID=6482135

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK94908337.2T DK0687256T3 (da)	1993-03-06	1994-02-18	Hydroxymethylfurazancarboxylsyrederivater og deresanvendelse ved behandling af kardiovaskulære sygdomme

Country Status (21)

Country	Link
US (1)	US5486531A (da)
EP (1)	EP0687256B1 (da)
JP (1)	JP3578456B2 (da)
KR (1)	KR960701029A (da)
CN (1)	CN1043140C (da)
AT (1)	ATE157660T1 (da)
AU (1)	AU676718B2 (da)
CA (1)	CA2155840C (da)
CZ (1)	CZ284264B6 (da)
DE (2)	DE4307105A1 (da)
DK (1)	DK0687256T3 (da)
ES (1)	ES2108977T3 (da)
FI (1)	FI954138A0 (da)
GR (1)	GR3024928T3 (da)
HU (1)	HUT72641A (da)
IL (1)	IL108856A (da)
PL (1)	PL177603B1 (da)
RU (1)	RU2134687C1 (da)
SK (1)	SK280354B6 (da)
WO (1)	WO1994020478A1 (da)
ZA (1)	ZA941533B (da)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE4401150A1 (de) *	1994-01-17	1995-07-20	Cassella Ag	Furazancarbonsäurederivate
US6313124B1 (en)	1997-07-23	2001-11-06	Dupont Pharmaceuticals Company	Tetrazine bicyclic compounds
US6124289A (en) *	1996-07-24	2000-09-26	Dupont Pharmaceuticals Co.	Azolo triazines and pyrimidines
US6060478A (en) *	1996-07-24	2000-05-09	Dupont Pharmaceuticals	Azolo triazines and pyrimidines
US6191131B1 (en)	1997-07-23	2001-02-20	Dupont Pharmaceuticals Company	Azolo triazines and pyrimidines
US7094782B1 (en)	1996-07-24	2006-08-22	Bristol-Myers Squibb Company	Azolo triazines and pyrimidines
RU2240321C2 (ru) *	2002-02-07	2004-11-20	ЗАО "АСГЛ-Исследовательские лаборатории"	Производные 3,4-бис(фуразан-3-ил)фуроксана, генерирующие оксид азота, активирующие растворимую форму гуанилатциклазы, ингибирующие агрегацию тромбоцитов и обладающие спазмолитическим, сосудорасширяющим, гипотензивным действием, и фармацевтическая композиция на их основе
DK1636215T3 (da) *	2003-05-23	2008-06-02	Basilea Pharmaceutica Ag	Furazanobenzimidazoler
US8822509B2 (en)	2006-12-29	2014-09-02	The University Of Queensland	Pain-relieving compositions and uses therefor
CN112125865B (zh) *	2020-09-30	2022-08-12	北京理工大学	氧化呋咱化合物的合成方法

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE3012862A1 (de) *	1980-04-02	1981-10-08	Cassella Ag, 6000 Frankfurt	Substituierte 1,2,5-oxdiazol-2-oxide als pharmazeutische wirkstoffe, ihre verwendung und sie enthaltende arzneimittel
DE3047730A1 (de) *	1980-12-18	1982-07-15	Cassella Ag, 6000 Frankfurt	3,4-bis-substituierte 1,2,5-oxdiazol-2-oxide, verfahren zu ihrer herstellung, ihre verwendung und sie enthaltende pharmazeutische zubereitungen

1993
- 1993-03-06 DE DE4307105A patent/DE4307105A1/de not_active Withdrawn
1994
- 1994-02-18 AU AU61414/94A patent/AU676718B2/en not_active Ceased
- 1994-02-18 KR KR1019950703761A patent/KR960701029A/ko not_active Ceased
- 1994-02-18 CZ CZ952281A patent/CZ284264B6/cs not_active IP Right Cessation
- 1994-02-18 CN CN94191395A patent/CN1043140C/zh not_active Expired - Fee Related
- 1994-02-18 SK SK1110-95A patent/SK280354B6/sk unknown
- 1994-02-18 CA CA002155840A patent/CA2155840C/en not_active Expired - Fee Related
- 1994-02-18 DE DE59403966T patent/DE59403966D1/de not_active Expired - Lifetime
- 1994-02-18 RU RU95118170A patent/RU2134687C1/ru active
- 1994-02-18 EP EP94908337A patent/EP0687256B1/de not_active Expired - Lifetime
- 1994-02-18 JP JP51951094A patent/JP3578456B2/ja not_active Expired - Fee Related
- 1994-02-18 WO PCT/EP1994/000459 patent/WO1994020478A1/de not_active Ceased
- 1994-02-18 AT AT94908337T patent/ATE157660T1/de not_active IP Right Cessation
- 1994-02-18 PL PL94310655A patent/PL177603B1/pl unknown
- 1994-02-18 HU HU9502603A patent/HUT72641A/hu unknown
- 1994-02-18 ES ES94908337T patent/ES2108977T3/es not_active Expired - Lifetime
- 1994-02-18 FI FI954138A patent/FI954138A0/fi unknown
- 1994-02-18 DK DK94908337.2T patent/DK0687256T3/da active
- 1994-03-04 ZA ZA941533A patent/ZA941533B/xx unknown
- 1994-03-04 IL IL108856A patent/IL108856A/xx active IP Right Grant
- 1994-03-07 US US08/207,280 patent/US5486531A/en not_active Expired - Lifetime
1997
- 1997-10-03 GR GR970402569T patent/GR3024928T3/el unknown

Also Published As

Publication number	Publication date
GR3024928T3 (en)	1998-01-30
IL108856A0 (en)	1994-06-24
CZ228195A3 (en)	1995-12-13
HU9502603D0 (en)	1995-11-28
FI954138A7 (fi)	1995-09-04
SK110095A3 (en)	1996-01-10
IL108856A (en)	1997-07-13
JPH08507299A (ja)	1996-08-06
PL177603B1 (pl)	1999-12-31
WO1994020478A1 (de)	1994-09-15
EP0687256B1 (de)	1997-09-03
EP0687256A1 (de)	1995-12-20
CZ284264B6 (cs)	1998-10-14
KR960701029A (ko)	1996-02-24
PL310655A1 (en)	1995-12-27
FI954138L (fi)	1995-09-04
US5486531A (en)	1996-01-23
AU6141494A (en)	1994-09-26
CN1119013A (zh)	1996-03-20
ZA941533B (en)	1994-10-06
SK280354B6 (sk)	1999-12-10
CN1043140C (zh)	1999-04-28
JP3578456B2 (ja)	2004-10-20
ATE157660T1 (de)	1997-09-15
FI954138A0 (fi)	1995-09-04
RU2134687C1 (ru)	1999-08-20
DE4307105A1 (de)	1994-09-08
DE59403966D1 (de)	1997-10-09
AU676718B2 (en)	1997-03-20
CA2155840C (en)	2005-05-24
HUT72641A (en)	1996-05-28
CA2155840A1 (en)	1994-09-15
ES2108977T3 (es)	1998-01-01

Publication	Publication Date	Title
DE122006000010I1 (de)	2006-06-29	Benzocyclobutyl- oder Indanyl-Alkyl-Amino-Alkyl substituierte 3- Benzazepin-2-ones, verwendbar in der Behandlung von kardiovaskularen Krankheiten
GR78945B (da)	1984-10-02
ATE206409T1 (de)	2001-10-15	N-(1-alkyl-5-phenyl-2,3,4,5-tetrahydro-1-h- benzo(b)(1,5)-diazepin-3-yl)-acetamide
TR199901905T2 (xx)	1999-10-21	2-(P�rin-9-il)-tetrahidrofuran-3,4-diol t�revleri.
NO944946D0 (no)	1994-12-20	Forgrenet-amino-substituerte tiazoler, fremgangsmåter for fremstilling av dem og farmasöytiske blandinger inneholdende dem
ES2105362T3 (es)	1997-10-16	Nuevos derivados de acidos quinolon- y naftiridoncarboxilicos.
ES2193241T3 (es)	2003-11-01	Nuevas n-2-oxo2.3.4.5-tetrajodrp-1h-1,5-benzodiazepin-3-il)-3-amidas.
DK0687256T3 (da)	1998-03-30	Hydroxymethylfurazancarboxylsyrederivater og deresanvendelse ved behandling af kardiovaskulære sygdomme
ES2194102T3 (es)	2003-11-16	Nuevas n-(2,4-dioxo-2,3,4,5-tetrahidro-1h-1,5-benzodiazepin-3-il)-3-amidas.
NO941514L (no)	1994-10-28	Kondenserte kinolyl-dihydropyridiner, deres fremstilling og anvendelse
NO933726L (no)	1993-12-15	Inhibitorer for kynureninase
ATE31928T1 (de)	1988-01-15	Acylamino-4-aza-1-adamantane, verfahren zu ihrer herstellung und ihre anwendung in der therapeutik.
SE8206548L (sv)	1983-05-19	Bensylidenderivat
ES2053686T3 (es)	1994-08-01	Nuevos di(met)acrilatos, procedimiento para su fabricacion y su empleo.
BR9407232A (pt)	1996-09-24	Compostos de tiocarbamoíla
DE69203142D1 (de)	1995-08-03	Von l-Glutaminsäure abgeleitete Süssungsmittel, Verfahren zu ihrer Herstellung.
ATE158576T1 (de)	1997-10-15	Alpha-aryl-alpha-hydroxy-beta- imidazolinylpropionsäureamide
DK0417875T3 (da)	1993-08-16	1-methoxypyrimidinyl-1H-1,2,4-triazol-3-sulfonsyrenitroanilider, fremgangsmåde til fremstilling heraf og deres anvendelse som middel med herbicid virkning
ATE165344T1 (de)	1998-05-15	Herstellung von symmetrischen und unsymmetrischen disubstituierten n-cyandithioiminocarbonaten
ATE168683T1 (de)	1998-08-15	Substituierte iminoacetonitrile mit myokardprotektiver wirkung