DK0690855T3 - Benzopyraner som kaliumkanalåbnere - Google Patents

Benzopyraner som kaliumkanalåbnere

Info

Publication number: DK0690855T3
Authority: DK; Denmark
Prior art keywords: pct; formula; image; dashed line; covalent bond
Prior art date: 1993-03-10

Application number

DK94910364.2T

Other languages

Danish (da)

English (en)

Inventor

Alexander Roderick Mackenzie

Sandra Marina Monaghan

Original Assignee

Pfizer Ltd

Pfizer Res & Dev

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1993-03-10

Filing date

1994-03-04

Publication date

1997-06-02

1993-03-10 Priority claimed from GB939304917A external-priority patent/GB9304917D0/en

1994-03-04 Application filed by Pfizer Ltd, Pfizer Res & Dev filed Critical Pfizer Ltd

1997-06-02 Application granted granted Critical

1997-06-02 Publication of DK0690855T3 publication Critical patent/DK0690855T3/da

Links

229940127315 Potassium Channel Openers Drugs 0.000 title 1
150000001562 benzopyrans Chemical class 0.000 title 1
150000001875 compounds Chemical class 0.000 abstract 2
125000003341 7 membered heterocyclic group Chemical group 0.000 abstract 1
201000010099 disease Diseases 0.000 abstract 1
208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
125000004464 hydroxyphenyl group Chemical group 0.000 abstract 1
230000004899 motility Effects 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1
210000002460 smooth muscle Anatomy 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
- C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
- C07D493/04—Ortho-condensed systems

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Bioinformatics & Cheminformatics (AREA)
Veterinary Medicine (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Public Health (AREA)
Pharmacology & Pharmacy (AREA)
Engineering & Computer Science (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Heart & Thoracic Surgery (AREA)
Cardiology (AREA)
Pulmonology (AREA)
Neurosurgery (AREA)
Biomedical Technology (AREA)
Endocrinology (AREA)
Reproductive Health (AREA)
Urology & Nephrology (AREA)
Neurology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Glass Compositions (AREA)
Curing Cements, Concrete, And Artificial Stone (AREA)
Diaphragms For Electromechanical Transducers (AREA)
Pyrane Compounds (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Saccharide Compounds (AREA)
Dental Preparations (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Cosmetics (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Other In-Based Heterocyclic Compounds (AREA)
Crystals, And After-Treatments Of Crystals (AREA)
Compounds Of Unknown Constitution (AREA)
Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)

DK94910364.2T 1993-03-10 1994-03-04 Benzopyraner som kaliumkanalåbnere DK0690855T3 (da)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
GB939304917A GB9304917D0 (en)	1993-03-10	1993-03-10	Benzopyrans
GB939308368A GB9308368D0 (en)	1993-03-10	1993-04-22	Benzopyrans

Publications (1)

Publication Number	Publication Date
DK0690855T3 true DK0690855T3 (da)	1997-06-02

Family

ID=26302564

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK94910364.2T DK0690855T3 (da)	1993-03-10	1994-03-04	Benzopyraner som kaliumkanalåbnere

Country Status (23)

Country	Link
US (1)	US5677324A (cs)
EP (1)	EP0690855B1 (cs)
JP (1)	JP3137649B2 (cs)
CN (1)	CN1119014A (cs)
AT (1)	ATE146468T1 (cs)
AU (1)	AU674940B2 (cs)
BR (1)	BR9406818A (cs)
CA (1)	CA2155837C (cs)
CZ (1)	CZ230895A3 (cs)
DE (1)	DE69401201T2 (cs)
DK (1)	DK0690855T3 (cs)
EG (1)	EG20542A (cs)
ES (1)	ES2097041T3 (cs)
FI (1)	FI115055B (cs)
GR (1)	GR3022517T3 (cs)
HU (1)	HUT73784A (cs)
IL (1)	IL108841A0 (cs)
MY (1)	MY110494A (cs)
NO (1)	NO953573D0 (cs)
NZ (1)	NZ262897A (cs)
PL (1)	PL310553A1 (cs)
SG (1)	SG42910A1 (cs)
WO (1)	WO1994020491A1 (cs)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US6417207B1 (en)	1999-05-12	2002-07-09	Nitromed, Inc.	Nitrosated and nitrosylated potassium channel activators, compositions and methods of use
AU2001286557A1 (en) *	2000-08-23	2002-03-04	Merck Frosst Canada And Co.	Method of treating or preventing urinary incontinence using prostanoid ep1 receptor antagonists
JP2007522201A (ja) *	2004-02-12	2007-08-09	ワーナー−ランバートカンパニーリミテッドライアビリティーカンパニー	毛成長の刺激方法
CN104487427B (zh) *	2012-06-25	2017-03-15	萨尼奥纳有限责任公司	四唑衍生物和它们作为钾通道调节剂的用途

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB1479518A (en) *	1973-12-27	1977-07-13	Erba Carlo Spa	5,6-benzo-ypsilon-pyrone derivatives
DE3811017A1 (de) *	1988-03-31	1989-10-19	Hoechst Ag	Ungesaettigte n-benzopyranyllactame
EP0346724A1 (de) *	1988-06-16	1989-12-20	MERCK PATENT GmbH	Chromanderivate

1994
- 1994-03-03 IL IL10884194A patent/IL108841A0/xx not_active IP Right Cessation
- 1994-03-04 NZ NZ262897A patent/NZ262897A/en unknown
- 1994-03-04 DE DE69401201T patent/DE69401201T2/de not_active Expired - Fee Related
- 1994-03-04 US US08/501,080 patent/US5677324A/en not_active Expired - Fee Related
- 1994-03-04 CA CA002155837A patent/CA2155837C/en not_active Expired - Fee Related
- 1994-03-04 CZ CZ952308A patent/CZ230895A3/cs unknown
- 1994-03-04 AU AU62826/94A patent/AU674940B2/en not_active Ceased
- 1994-03-04 DK DK94910364.2T patent/DK0690855T3/da active
- 1994-03-04 EP EP94910364A patent/EP0690855B1/en not_active Expired - Lifetime
- 1994-03-04 MY MYPI94000520A patent/MY110494A/en unknown
- 1994-03-04 BR BR9406818A patent/BR9406818A/pt not_active Application Discontinuation
- 1994-03-04 PL PL94310553A patent/PL310553A1/xx unknown
- 1994-03-04 CN CN94191420A patent/CN1119014A/zh active Pending
- 1994-03-04 JP JP06519578A patent/JP3137649B2/ja not_active Expired - Fee Related
- 1994-03-04 AT AT94910364T patent/ATE146468T1/de not_active IP Right Cessation
- 1994-03-04 HU HU9501918A patent/HUT73784A/hu unknown
- 1994-03-04 ES ES94910364T patent/ES2097041T3/es not_active Expired - Lifetime
- 1994-03-04 WO PCT/EP1994/000637 patent/WO1994020491A1/en not_active Ceased
- 1994-03-04 SG SG1996000633A patent/SG42910A1/en unknown
- 1994-03-07 EG EG13694A patent/EG20542A/xx active
1995
- 1995-09-08 FI FI954218A patent/FI115055B/fi not_active IP Right Cessation
- 1995-09-11 NO NO953573A patent/NO953573D0/no unknown
1997
- 1997-02-12 GR GR960403348T patent/GR3022517T3/el unknown

Also Published As

Publication number	Publication date
WO1994020491A1 (en)	1994-09-15
HU9501918D0 (en)	1995-09-28
CZ230895A3 (en)	1995-12-13
ATE146468T1 (de)	1997-01-15
CN1119014A (zh)	1996-03-20
BR9406818A (pt)	1996-09-10
EP0690855B1 (en)	1996-12-18
EP0690855A1 (en)	1996-01-10
JPH08503225A (ja)	1996-04-09
FI954218A0 (fi)	1995-09-08
NO953573L (no)	1995-09-11
NO953573D0 (no)	1995-09-11
FI115055B (fi)	2005-02-28
NZ262897A (en)	1997-06-24
AU674940B2 (en)	1997-01-16
DE69401201T2 (de)	1997-04-17
HUT73784A (en)	1996-09-30
MY110494A (en)	1998-06-30
PL310553A1 (en)	1995-12-27
DE69401201D1 (de)	1997-01-30
CA2155837A1 (en)	1994-09-15
CA2155837C (en)	1999-07-27
ES2097041T3 (es)	1997-03-16
JP3137649B2 (ja)	2001-02-26
FI954218L (fi)	1995-09-08
SG42910A1 (en)	1997-10-17
AU6282694A (en)	1994-09-26
IL108841A0 (en)	1994-06-24
GR3022517T3 (en)	1997-05-31
EG20542A (en)	1999-07-31
US5677324A (en)	1997-10-14

Publication	Publication Date	Title
ES2185054T3 (es)	2003-04-16	Derivados de benzopirano.
DE69327541D1 (en)	2000-02-10	4-arylmethyloxymethyl piperidine als tachykinin antagonisten
ATE229524T1 (de)	2002-12-15	Distamycin a analoga als antitumor- oder antivirale wirkstoffe
DE69227125D1 (de)	1998-10-29	Antirheumatische naphthyridinderivate.
PT638075E (pt)	2002-06-28	Inibidor da reaccao de maillard
AU2936195A (en)	1996-02-16	Cyclic amide derivatives for protecting against ultraviolet rays
DK0690855T3 (da)	1997-06-02	Benzopyraner som kaliumkanalåbnere
DK0808326T3 (da)	2001-10-01	Basiske oxazolinamidderivater af GE2270 og GE2270-lignende antibiotika
ES2128572T3 (es)	1999-05-16	Utilizacion de los derivados de cefem como agentes antimetastaticos.
IL110845A0 (en)	1994-11-28	Pyridazinone derivatives or their salts, processes or their production and anti-shock agents containing them
DK0699198T3 (da)	1999-11-22	N-benzoylmethyl-substituerede paroxetinderivater
FI951277A0 (fi)	1995-03-17	Uudet N,N,N',N'-tetrasubstituoituneet 1,2-etaanidiamiinijohdannaisyhdisteet
SE8501988L (sv)	1985-10-26	Iminotiazolidinderivat
DK0788491T3 (da)	2000-05-08	6-Polyfluoralkoxy- og 6-polyfluoralkyl-2-aminobenzothiazol-derivater
DE69430074D1 (de)	2002-04-11	Analgetische 4-arylisoindolen
BR9611572A (pt)	1999-03-30	Produção de um sal de ácido clavulânico