DK0690863T3 - Tetracykliske forbindelser som dopamin-agonister - Google Patents
Tetracykliske forbindelser som dopamin-agonisterInfo
- Publication number
- DK0690863T3 DK0690863T3 DK94912799T DK94912799T DK0690863T3 DK 0690863 T3 DK0690863 T3 DK 0690863T3 DK 94912799 T DK94912799 T DK 94912799T DK 94912799 T DK94912799 T DK 94912799T DK 0690863 T3 DK0690863 T3 DK 0690863T3
- Authority
- DK
- Denmark
- Prior art keywords
- image
- dopamine agonists
- treatment
- tetracyclic compounds
- compounds
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/26—Psychostimulants, e.g. nicotine, cocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P39/00—General protective or antinoxious agents
- A61P39/02—Antidotes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D495/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
- C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
- C07D513/04—Ortho-condensed systems
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Psychiatry (AREA)
- Hospice & Palliative Care (AREA)
- Cardiology (AREA)
- Pain & Pain Management (AREA)
- Heart & Thoracic Surgery (AREA)
- Toxicology (AREA)
- Otolaryngology (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US4342493A | 1993-04-06 | 1993-04-06 | |
| US20998294A | 1994-03-17 | 1994-03-17 | |
| PCT/US1994/002894 WO1994022858A1 (en) | 1993-04-06 | 1994-03-18 | Tetracyclic compounds as dopamine agonists |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK0690863T3 true DK0690863T3 (da) | 2003-06-30 |
Family
ID=26720416
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK94912799T DK0690863T3 (da) | 1993-04-06 | 1994-03-18 | Tetracykliske forbindelser som dopamin-agonister |
Country Status (15)
| Country | Link |
|---|---|
| US (1) | US5597832A (pt) |
| EP (1) | EP0690863B1 (pt) |
| JP (1) | JP2710695B2 (pt) |
| KR (1) | KR100383342B1 (pt) |
| CN (1) | CN1046723C (pt) |
| AT (1) | ATE233765T1 (pt) |
| AU (1) | AU677842B2 (pt) |
| BR (1) | BR9405972A (pt) |
| DE (1) | DE69432217T2 (pt) |
| DK (1) | DK0690863T3 (pt) |
| ES (1) | ES2193158T3 (pt) |
| FI (1) | FI954738A7 (pt) |
| NO (1) | NO311762B1 (pt) |
| PT (1) | PT690863E (pt) |
| WO (1) | WO1994022858A1 (pt) |
Families Citing this family (27)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5659037A (en) * | 1994-08-18 | 1997-08-19 | Abbott Laboratories | Process for preparing chiral tetracyclic dopaminergic compounds |
| JP3036847B2 (ja) | 1995-01-13 | 2000-04-24 | サマーセット・ファーマシューティカルズ・インコーポレイテッド | デスメチルセレギリンを用いる方法および医薬組成物 |
| WO1996025411A1 (en) | 1995-02-15 | 1996-08-22 | Neurogen Corporation | Certain bridged 4-phenyl-2-aminomethylimidazoles; new dopamine receptor subtype specific ligands |
| US5668141A (en) * | 1996-04-02 | 1997-09-16 | Abbott Laboratories | Trans-2,6-,3,6-and 4,6-diaza-5,6,6a,7,8,12b-hexahydrobenzo[c]phenanthrene compounds as dopamine agonists |
| DE19644228A1 (de) * | 1996-10-24 | 1998-04-30 | Merck Patent Gmbh | Thienopyrimidine |
| EP1006794B1 (en) * | 1997-03-12 | 2007-11-28 | Robert W. Esmond | A method for treating or preventing alzheimer's disease |
| US6193954B1 (en) | 1997-03-21 | 2001-02-27 | Abbott Laboratories | Formulations for pulmonary delivery of dopamine agonists |
| AU750808B2 (en) | 1997-10-03 | 2002-07-25 | Cary Medical Corporation | Compositon for the treatment of nicotine addiction containing a nicotine receptor antagonist and an anti-depressant or anti-anxiety drug |
| US20040058873A1 (en) * | 1998-03-12 | 2004-03-25 | Esmond Robert W. | Method for treating or preventing Alzheimer's disease |
| GB9828861D0 (en) * | 1998-12-31 | 1999-02-17 | Danbiosyst Uk | Compositions |
| US6147226A (en) * | 1999-02-16 | 2000-11-14 | Great Lakes Chemical Corporation | Synthesis of cyclopentyl 2-thienyl ketone, tiletamine and tiletamine acid addition salts, such as tiletamine hydrochloride |
| US5969159A (en) * | 1999-02-16 | 1999-10-19 | Great Lakes Chemical Corporation | Synthesis of cyclopentyl 2-thienyl ketone tiletamine and tiletamine acid addition salts such as tiletamine hydrochloride |
| US6638929B2 (en) * | 1999-12-29 | 2003-10-28 | Wyeth | Tricyclic protein kinase inhibitors |
| PL363365A1 (en) * | 2000-08-16 | 2004-11-15 | Pharmacia & Upjohn Company | Compounds for the treatment of addictive disorders |
| US20070243240A9 (en) * | 2000-08-24 | 2007-10-18 | Fred Windt-Hanke | Transdermal therapeutic system |
| DE10043321B4 (de) * | 2000-08-24 | 2005-07-28 | Neurobiotec Gmbh | Verwendung eines transdermalen therapeutischen Systems zur Behandlung der Parkinsonschen Krankheit, zur Behandlung und Prävention des prämenstruellen Syndroms und zur Lactationshemmung |
| DE10053397A1 (de) * | 2000-10-20 | 2002-05-02 | Schering Ag | Verwendung eines dopaminergen Wirkstoffes zur Behandlung von dopaminerg behandelbaren Erkrankungen |
| DE10064453A1 (de) * | 2000-12-16 | 2002-07-04 | Schering Ag | Verwendung eines dopaminergen Wirkstoffes zur Behandlung von dopaminerg behandelbaren Erkrankungen |
| DE60323339D1 (de) | 2002-02-15 | 2008-10-16 | Darpharma Inc | Monoester und asymmetrisch substituierte diester prodrugs der dopamin-d1-rezeptor-agonisten |
| US20100168085A1 (en) * | 2003-05-22 | 2010-07-01 | Yesa Research And Development Co. Ltd. At The Weizmann Institute Of Science | Dopamine and agonists and antagonists thereof for modulation of suppressive activity of CD4+CD25+ regulatory T cells |
| WO2005055920A2 (en) * | 2003-12-09 | 2005-06-23 | Yeda Research And Development Co. Ltd. | Compositions and methods for treatment of psychiatric disorders |
| EP1699450A4 (en) * | 2003-12-23 | 2009-11-11 | Darpharma Inc | Simultaneous administration of dopamine receptor bindings |
| NZ570606A (en) * | 2006-02-21 | 2011-11-25 | Purdue Research Foundation | Trans-fused chromenoisoquinolines, synthesis and methods for use |
| WO2010124005A1 (en) | 2009-04-21 | 2010-10-28 | Purdue Research Foundation | Octahydrobenzoisoquinoline modulators of dopamine receptors and uses therefor |
| WO2013134047A2 (en) | 2012-03-07 | 2013-09-12 | The Mclean Hospital Corporation | Aminoquinoline derivatives and uses thereof |
| CN103387583B (zh) * | 2012-05-09 | 2018-04-13 | 中国科学院上海药物研究所 | 二芳基并[a,g]喹嗪类化合物、其制备方法、药物组合物及其应用 |
| RU2537170C1 (ru) * | 2013-11-20 | 2014-12-27 | Войсковая Часть 41598 | Средство профилактики церебральной формы острой лучевой болезни |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2691024A (en) * | 1952-05-26 | 1954-10-05 | Schenley Ind Inc | Dihydropyrrolo-(3.2-c) quinoline derivatives |
| US3541100A (en) * | 1967-12-14 | 1970-11-17 | American Cyanamid Co | Benzheteroazolo(2,3-a)isoquinolium salts |
| GB1379387A (en) * | 1970-12-11 | 1975-01-02 | Agfa Gevaert | Photoconductive recording materials |
| US3943137A (en) * | 1973-07-09 | 1976-03-09 | University Of Kansas Endowment Association | Acronycine derivatives |
| NL7605526A (nl) * | 1976-05-24 | 1977-11-28 | Akzo Nv | Nieuwe tetracyclische derivaten. |
| US4340600A (en) * | 1980-05-22 | 1982-07-20 | Smithkline Corporation | Renal dilating methods and compositions using 4-(3,4-dihydroxyphenyl)-1,2,3,4-tetrahydroisoquinolines |
| US4282227A (en) * | 1980-05-22 | 1981-08-04 | Smithkline Corporation | Renal vasodilating 3,4-dihydroxyphenyltetrahydrothienopyridines |
| US5047536A (en) * | 1989-03-17 | 1991-09-10 | Purdue Research Foundation | Hexahydrobenzo(A)phenanthridine compounds |
| WO1993024462A1 (en) * | 1992-05-26 | 1993-12-09 | Purdue Research Foundation | Substituted-hexahydrobenzo[a]phenanthridines |
-
1994
- 1994-03-18 FI FI954738A patent/FI954738A7/fi unknown
- 1994-03-18 JP JP6522116A patent/JP2710695B2/ja not_active Expired - Lifetime
- 1994-03-18 BR BR9405972A patent/BR9405972A/pt not_active Application Discontinuation
- 1994-03-18 WO PCT/US1994/002894 patent/WO1994022858A1/en not_active Ceased
- 1994-03-18 CN CN94192241A patent/CN1046723C/zh not_active Expired - Lifetime
- 1994-03-18 DE DE69432217T patent/DE69432217T2/de not_active Expired - Lifetime
- 1994-03-18 AU AU65203/94A patent/AU677842B2/en not_active Expired
- 1994-03-18 ES ES94912799T patent/ES2193158T3/es not_active Expired - Lifetime
- 1994-03-18 EP EP94912799A patent/EP0690863B1/en not_active Expired - Lifetime
- 1994-03-18 AT AT94912799T patent/ATE233765T1/de active
- 1994-03-18 DK DK94912799T patent/DK0690863T3/da active
- 1994-03-18 KR KR1019950704355A patent/KR100383342B1/ko not_active Expired - Lifetime
- 1994-03-18 PT PT94912799T patent/PT690863E/pt unknown
- 1994-11-10 US US08/337,348 patent/US5597832A/en not_active Expired - Lifetime
-
1995
- 1995-10-05 NO NO19953957A patent/NO311762B1/no not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| JP2710695B2 (ja) | 1998-02-10 |
| CN1124489A (zh) | 1996-06-12 |
| FI954738L (fi) | 1995-12-05 |
| BR9405972A (pt) | 1995-12-12 |
| FI954738A0 (fi) | 1995-10-05 |
| EP0690863B1 (en) | 2003-03-05 |
| JPH08508487A (ja) | 1996-09-10 |
| KR100383342B1 (ko) | 2003-08-25 |
| US5597832A (en) | 1997-01-28 |
| DE69432217T2 (de) | 2004-04-08 |
| NO311762B1 (no) | 2002-01-21 |
| DE69432217D1 (de) | 2003-04-10 |
| ATE233765T1 (de) | 2003-03-15 |
| FI954738A7 (fi) | 1995-12-05 |
| CN1046723C (zh) | 1999-11-24 |
| ES2193158T3 (es) | 2003-11-01 |
| WO1994022858A1 (en) | 1994-10-13 |
| NO953957L (no) | 1995-11-21 |
| PT690863E (pt) | 2003-07-31 |
| NO953957D0 (no) | 1995-10-05 |
| AU677842B2 (en) | 1997-05-08 |
| AU6520394A (en) | 1994-10-24 |
| EP0690863A1 (en) | 1996-01-10 |
| EP0690863A4 (en) | 1995-11-07 |
| KR960701870A (ko) | 1996-03-28 |
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