DK0693077T3 - Antivirusforbindelser - Google Patents

Antivirusforbindelser

Info

Publication number: DK0693077T3
Authority: DK; Denmark
Prior art keywords: pct; nucleoside analog; mono; sec; formula
Prior art date: 1993-04-05

Application number

DK94912709T

Other languages

English (en)

Inventor

Kjell Torgeir Stokke

Bernt Borretzen

Are Dalen

Finn Myhren

Original Assignee

Norsk Hydro As

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1993-04-05

Filing date

1994-04-05

Publication date

1999-06-14

1994-04-05 Application filed by Norsk Hydro As filed Critical Norsk Hydro As

1999-06-14 Application granted granted Critical

1999-06-14 Publication of DK0693077T3 publication Critical patent/DK0693077T3/da

Links

230000002155 anti-virotic effect Effects 0.000 title 1
239000002777 nucleoside Substances 0.000 abstract 3
150000003833 nucleoside derivatives Chemical class 0.000 abstract 3
125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 2
125000002252 acyl group Chemical group 0.000 abstract 1
QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 abstract 1
150000001875 compounds Chemical class 0.000 abstract 1
125000004122 cyclic group Chemical group 0.000 abstract 1
235000014113 dietary fatty acids Nutrition 0.000 abstract 1
229930195729 fatty acid Natural products 0.000 abstract 1
239000000194 fatty acid Substances 0.000 abstract 1
150000004665 fatty acids Chemical class 0.000 abstract 1
125000000623 heterocyclic group Chemical group 0.000 abstract 1
150000002771 monosaccharide derivatives Chemical class 0.000 abstract 1
235000021315 omega 9 monounsaturated fatty acids Nutrition 0.000 abstract 1
229910052760 oxygen Inorganic materials 0.000 abstract 1
239000001301 oxygen Substances 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
- C07H19/06—Pyrimidine radicals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
- C07H19/052—Imidazole radicals
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
- C07H19/056—Triazole or tetrazole radicals
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
- C07H19/16—Purine radicals

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Engineering & Computer Science (AREA)
Biochemistry (AREA)
Biotechnology (AREA)
Genetics & Genomics (AREA)
Molecular Biology (AREA)
Oncology (AREA)
Public Health (AREA)
Virology (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
Communicable Diseases (AREA)
Veterinary Medicine (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Saccharide Compounds (AREA)
Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Crystals, And After-Treatments Of Crystals (AREA)

DK94912709T 1993-04-05 1994-04-05 Antivirusforbindelser DK0693077T3 (da)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
GB939307043A GB9307043D0 (en)	1993-04-05	1993-04-05	Chemical compounds
PCT/NO1994/000071 WO1994022887A1 (en)	1993-04-05	1994-04-05	New antiviral compounds

Publications (1)

Publication Number	Publication Date
DK0693077T3 true DK0693077T3 (da)	1999-06-14

Family

ID=10733340

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK94912709T DK0693077T3 (da)	1993-04-05	1994-04-05	Antivirusforbindelser

Country Status (20)

Country	Link
US (1)	US6153594A (da)
EP (1)	EP0693077B1 (da)
JP (1)	JP3049258B2 (da)
KR (1)	KR100309194B1 (da)
AT (1)	ATE171457T1 (da)
AU (1)	AU685104B2 (da)
CA (1)	CA2158853C (da)
CZ (1)	CZ287755B6 (da)
DE (1)	DE69413529T2 (da)
DK (1)	DK0693077T3 (da)
ES (1)	ES2124883T3 (da)
FI (1)	FI111370B (da)
GB (1)	GB9307043D0 (da)
HU (1)	HU228064B1 (da)
NZ (1)	NZ263888A (da)
PL (1)	PL177263B1 (da)
RU (1)	RU2139884C1 (da)
SK (1)	SK281231B6 (da)
UA (1)	UA41361C2 (da)
WO (1)	WO1994022887A1 (da)

Families Citing this family (38)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB9515279D0 (en) *	1995-07-25	1995-09-20	Norsk Hydro As	Improved therapeutic agents
US5869493A (en) *	1996-02-16	1999-02-09	Medivir Ab	Acyclic nucleoside derivatives
US6703394B2 (en)	1996-02-16	2004-03-09	Medivir Ab	Acyclic nucleoside derivatives
US5795909A (en)	1996-05-22	1998-08-18	Neuromedica, Inc.	DHA-pharmaceutical agent conjugates of taxanes
CA2278056C (en) *	1997-01-24	2006-12-12	Norsk Hydro Asa	Gemcitabine derivatives
US5891881A (en) *	1997-11-21	1999-04-06	Clarion Pharmaceuticals Inc.	Aminoheterocycle-substituted glycerols
EP1042341A1 (en) *	1997-11-25	2000-10-11	Protarga Inc.	Nucleoside analog compositions and uses thereof
BR9911965A (pt)	1998-07-09	2001-05-29	Sankyo Co	Composto, derivado de éster, éter ou n-alquilcarbamoìla farmaceuticamente aceitáveis, composição farmacêutica, uso de um composto, processo para o tratamento ou prevenção de uma infecção bacteriana, streptomices griseus, derivado de amida, processo para preparar um composto, e, cepa de streptomyces griseus
PT2415776T (pt) *	1998-08-10	2016-07-07	Novartis Ag	Beta-l-2'-desoxi-nucleosidos para o tratamento da hepatite b
US6403564B1 (en)	1998-10-16	2002-06-11	Schering Corporation	Ribavirin-interferon alfa combination therapy for eradicating detectable HCV-RNA in patients having chronic hepatitis C infection
US6277830B1 (en)	1998-10-16	2001-08-21	Schering Corporation	5′-amino acid esters of ribavirin and the use of same to treat hepatitis C with interferon
TR200101085T2 (tr) *	1998-10-16	2001-08-21	Schering Corporation	Kronik hepatit C enfeksiyonlu hastalarda algılanabilir HCV-RNA'nın yok edilmesi için birleşik ribavirin-interferon alfa tedavisi
US7235583B1 (en)	1999-03-09	2007-06-26	Luitpold Pharmaceuticals, Inc.,	Fatty acid-anticancer conjugates and uses thereof
TWI245047B (en)	1999-08-20	2005-12-11	Sankyo Co	Novel A-500359 derivatives
US7638496B2 (en)	2000-02-15	2009-12-29	Valeant Pharmaceuticals North America	Nucleoside analogs with carboxamidine modified monocyclic base
US6924270B2 (en)	2000-04-20	2005-08-02	Schering Corporation	Ribavirin-interferon alfa combination therapy for eradicating detectable HCV-RNA in patients having chronic hepatitis C infection
MY164523A (en)	2000-05-23	2017-12-29	Univ Degli Studi Cagliari	Methods and compositions for treating hepatitis c virus
EP1736478B1 (en) *	2000-05-26	2015-07-22	IDENIX Pharmaceuticals, Inc.	Methods and compositions for treating flaviviruses and pestiviruses
AU2003222197A1 (en) *	2002-01-16	2003-09-02	The Regents Of The University Of California	Inhibition of rna function
CN1678326A (zh)	2002-06-28	2005-10-05	埃迪尼克斯(开曼)有限公司	用于治疗黄病毒感染的2'－c－甲基－3'－o－l－缬氨酸酯核糖呋喃基胞苷
NZ537662A (en)	2002-06-28	2007-10-26	Idenix Cayman Ltd	2'-C-methyl-3'-O-L-valine ester ribofuranosyl cytidine for treatment of flaviviridae infections
US7608600B2 (en)	2002-06-28	2009-10-27	Idenix Pharmaceuticals, Inc.	Modified 2′ and 3′-nucleoside prodrugs for treating Flaviviridae infections
US20040077607A1 (en) *	2002-10-21	2004-04-22	Uckun Fatih M.	Aryl phosphate derivatives of d4T with potent anti-viral activity against hemorrhagic fever viruses
WO2004039995A1 (en) *	2002-11-01	2004-05-13	Evogenix Pty Ltd	Mutagenesis methods using ribavirin and/or rna replicases
LT1576138T (lt)	2002-11-15	2017-06-26	Idenix Pharmaceuticals Llc	2`-šakoti nukleozidai derinyje su interferonu ir flaviviridae mutacija
TWI332507B (en) *	2002-11-19	2010-11-01	Hoffmann La Roche	Antiviral nucleoside derivatives
AU2003300901A1 (en)	2002-12-12	2004-06-30	Idenix (Cayman) Limited	Process for the production of 2'-branched nucleosides
WO2004084453A2 (en) *	2003-03-20	2004-09-30	Microbiologica Quimica E Farmaceutica Ltd.	METHODS OF MANUFACTURE OF 2'-DEOXY-β-L-NUCLEOSIDES
JP2007509994A (ja) *	2003-11-03	2007-04-19	コグニス・アイピー・マネージメント・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツング	アシルリボヌクレオシドおよびアシルデオキシリボヌクレオシド
FR2874016B1 (fr) *	2004-06-30	2006-11-24	Centre Nat Rech Scient Cnrse	Nanoparticules de derives de la gemcitabine
US9029345B2 (en) *	2005-03-16	2015-05-12	Case Western Reserve University	Selective inhibitors of translesion DNA replication
WO2006101911A1 (en)	2005-03-16	2006-09-28	Case Western Reserve University	Selective inhibitors of translesion dna replication
NO324263B1 (no) *	2005-12-08	2007-09-17	Clavis Pharma Asa	Kjemiske forbindelser, anvendelse derav ved behandling av kreft, samt farmasoytiske preparater som omfatter slike forbindelser
ES2422290T3 (es)	2005-12-23	2013-09-10	Idenix Pharmaceuticals Inc	Procedimiento para preparar un producto intermedio sintético para la preparación de nucleósidos ramificados
US8497292B2 (en) *	2005-12-28	2013-07-30	Translational Therapeutics, Inc.	Translational dysfunction based therapeutics
WO2009042767A1 (en) *	2007-09-26	2009-04-02	Mount Sinai School Of Medicine	Azacytidine analogues and uses thereof
US9988680B2 (en)	2011-09-01	2018-06-05	Case Western Reserve University	Non-natural nucleosides as theranostic agents
US9821173B2 (en)	2013-02-08	2017-11-21	Case Western Reserve University	Anti-cancer agents and methods of use

Family Cites Families (23)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3A (en) *	1836-08-01	1836-08-11	Thomas Blanchard	Machine for turning and wooden sheaves and pins for ships' tackle blocks and pulleys
US3920630A (en) *	1970-09-24	1975-11-18	Upjohn Co	2,2{40 -Anhydro-ara-cytidine compounds and process of preparation
GB1325798A (en) *	1970-09-24	1973-08-08	Upjohn Co	Derivatives of 2,2-anhydro-ara-cytidine
US3984396A (en) *	1971-06-01	1976-10-05	Icn Pharmaceuticals, Inc.	1-(β,-D-ribofuranosyl)-1,2,4-triazole acid esters
US3998807A (en) *	1972-03-03	1976-12-21	Syntex (U.S.A.) Inc.	Arabinofuranosyl cytosines and methods of making
GB1482736A (en) *	1974-03-18	1977-08-10	Icn Pharmaceuticals	1-(beta-d-ribofuranosyl)-1,2,4-triazole acid derivatives
US3960836A (en) *	1974-07-22	1976-06-01	Eli Lilly And Company	Acylated derivatives of pyrazofurin and process for their preparation
JPS5159880A (en) *	1974-11-22	1976-05-25	Asahi Chemical Ind	N44 ashirunukureoshidojikarubonsanesuteruno seiho
DE3100478A1 (de) *	1981-01-09	1982-08-12	Dr. Thilo & Co GmbH, 8021 Sauerlach	5'ester von pyrimidinnucleosiden mit antiviraler wirksamkeit, verfahren zur herstellung und daraus hergestellte arzneimittel
US4531001A (en) *	1982-03-23	1985-07-23	Brigham Young University	2-β-D-ribofuranosylselenazole-4-carboxamide compounds
JPH0655755B2 (ja) *	1985-01-23	1994-07-27	富山化学工業株式会社	新規な５−フルオロ−２′−デオキシウリジン−３′−ホスフエ−ト誘導体およびその塩
US4684631A (en) *	1984-10-09	1987-08-04	Toyama Chemical Co., Ltd.	Novel 5-fluoro-2-deoxyuridine derivatives and salts thereof, process for producing the same, and antitumor agents containing the same
US5223263A (en) *	1988-07-07	1993-06-29	Vical, Inc.	Liponucleotide-containing liposomes
GB8512330D0 (en) *	1985-05-15	1985-06-19	Wellcome Found	Antiviral compounds
US4751221A (en) *	1985-10-18	1988-06-14	Sloan-Kettering Institute For Cancer Research	2-fluoro-arabinofuranosyl purine nucleosides
JPS6483092A (en) *	1987-09-24	1989-03-28	Arakawa Chotaro & Co	Novel n6,n6-dimethyladenosine derivative having carcinostatic activity, its production and carcinostatic agent containing said derivative as active component
EP0355031A3 (de) *	1988-08-17	1990-12-27	MATTHES, Eckart, Dr.	Substituierte Pyrimidinnucleoside, Verfahren zu ihrer Herstellung und sie enthaltende pharmazeutische Mittel
JPH0278696A (ja) *	1988-09-13	1990-03-19	Shoichiro Ozaki	５−フルオロウラシル誘導体
IE980216A1 (en) *	1989-04-17	2000-02-23	Scotia Holdings Plc	Anti-virals
EP0450102A4 (en) *	1989-10-26	1992-05-06	Yamasa Shoyu Kabushiki Kaisha	Nucleoside derivative
GB2260319B (en) *	1991-10-07	1995-12-06	Norsk Hydro As	Acyl derivatives of nucleosides and nucleoside analogues having anti-viral activity
US5405837A (en) *	1993-05-18	1995-04-11	Indiana University Foundation	Method for the treatment of neoplastic disease utilizing tiazofurin and ribavirin
RU2071773C1 (ru) *	1993-07-19	1997-01-20	Товарищество с ограниченной ответственностью "Полисан"	Лекарственное средство для лечения синдромов приобретенного иммунодефицита, в том числе вич-обусловленных

1993
- 1993-04-05 GB GB939307043A patent/GB9307043D0/en active Pending
1994
- 1994-04-05 CA CA002158853A patent/CA2158853C/en not_active Expired - Lifetime
- 1994-04-05 HU HU9502896A patent/HU228064B1/hu unknown
- 1994-04-05 PL PL94310970A patent/PL177263B1/pl unknown
- 1994-04-05 EP EP94912709A patent/EP0693077B1/en not_active Expired - Lifetime
- 1994-04-05 KR KR1019950704292A patent/KR100309194B1/ko not_active Expired - Fee Related
- 1994-04-05 UA UA95104367A patent/UA41361C2/uk unknown
- 1994-04-05 ES ES94912709T patent/ES2124883T3/es not_active Expired - Lifetime
- 1994-04-05 WO PCT/NO1994/000071 patent/WO1994022887A1/en not_active Ceased
- 1994-04-05 NZ NZ263888A patent/NZ263888A/en not_active IP Right Cessation
- 1994-04-05 AT AT94912709T patent/ATE171457T1/de active
- 1994-04-05 DE DE69413529T patent/DE69413529T2/de not_active Expired - Lifetime
- 1994-04-05 RU RU95119386A patent/RU2139884C1/ru active
- 1994-04-05 JP JP6521952A patent/JP3049258B2/ja not_active Expired - Lifetime
- 1994-04-05 DK DK94912709T patent/DK0693077T3/da active
- 1994-04-05 AU AU65141/94A patent/AU685104B2/en not_active Expired
- 1994-04-05 SK SK1233-95A patent/SK281231B6/sk not_active IP Right Cessation
- 1994-04-05 US US08/532,754 patent/US6153594A/en not_active Expired - Lifetime
- 1994-04-05 CZ CZ19952593A patent/CZ287755B6/cs not_active IP Right Cessation
1995
- 1995-10-04 FI FI954727A patent/FI111370B/fi not_active IP Right Cessation

Also Published As

Publication number	Publication date
UA41361C2 (uk)	2001-09-17
ATE171457T1 (de)	1998-10-15
CA2158853A1 (en)	1994-10-13
HU228064B1 (en)	2012-09-28
US6153594A (en)	2000-11-28
FI954727L (fi)	1995-10-04
EP0693077A1 (en)	1996-01-24
EP0693077B1 (en)	1998-09-23
SK123395A3 (en)	1996-04-03
NZ263888A (en)	1998-05-27
FI954727A0 (fi)	1995-10-04
FI111370B (fi)	2003-07-15
JP3049258B2 (ja)	2000-06-05
RU2139884C1 (ru)	1999-10-20
JPH08508477A (ja)	1996-09-10
HK1003437A1 (en)	1998-10-30
WO1994022887A1 (en)	1994-10-13
KR100309194B1 (ko)	2002-06-20
DE69413529D1 (de)	1998-10-29
CZ287755B6 (en)	2001-01-17
ES2124883T3 (es)	1999-02-16
HU9502896D0 (en)	1995-11-28
SK281231B6 (sk)	2001-01-18
HUT73659A (en)	1996-09-30
CZ259395A3 (en)	1996-06-12
GB9307043D0 (en)	1993-05-26
AU685104B2 (en)	1998-01-15
PL177263B1 (pl)	1999-10-29
DE69413529T2 (de)	1999-04-29
CA2158853C (en)	1999-07-27
AU6514194A (en)	1994-10-24
PL310970A1 (en)	1996-01-22

Publication	Publication Date	Title
DK0693077T3 (da)	1999-06-14	Antivirusforbindelser
ES2085876T3 (es)	1996-06-16	Derivado de bifenilmetano, su utilizacion y composiciones farmacologicas que contienen el mismo.
SE9100342D0 (sv)	1991-02-04	Novel steroid esters
ITMI922699A1 (it)	1994-05-26	Esteri nitrici con attivita' farmacologica e procedimento per la loro preparazione
MX9205137A (es)	1993-04-01	O-heteroaril, o-alquilheteroaril, o-alquenilheteroaril y o-alquinilheteroarilmacrolidas que tienen actividad inmunosupresora.
TR200001982T2 (tr)	2001-02-21	Farmasötik vurulu salınımlı oral dozaj şekli.
ES2124214T3 (es)	1999-02-01	Gangliosidos modificados y sus derivados funcionales.
EP0642525A1 (en)	1995-03-15	Chemical compounds.
ATE16488T1 (de)	1985-11-15	M-4- und isom-4-derivate, ihre herstellung und diese enthaltende zusammensetzungen.
ATE214698T1 (de)	2002-04-15	Neue carbamazepin hapten analoge
KR0140401B1 (en)	1998-06-01	Anti-bloom triglyceride compositions
ES466037A1 (es)	1978-10-01	Un procedimiento para preparar derivados de oleandomicina.
DE69028320D1 (de)	1996-10-02	Illudin-analoge, verwendet als antitumormittel
ES2164869T3 (es)	2002-03-01	Conjugados lipidos especificos de nucleosidos-difosfato y su uso como medicamentos.
ATE92498T1 (de)	1993-08-15	Primycinkomponenten und verfahren zur trennung des antibiotischen komplexes.
ES8609482A1 (es)	1986-09-01	Un metodo para producir acido dihidrodesoxigriseolico y sa- les y esteres del mismo
DE3586344D1 (de)	1992-08-20	Esterderivate vom antibiotikum l 17046.
ES2074264T3 (es)	1995-09-01	Esteres de aminoacidos de la hidroquinona, su procedimiento de preparacion y composiciones farmaceuticas o cosmeticas que los contienen.
BR9707342A (pt)	1999-07-20	Dihidrobensofurano e compostos correlatod úteis como agentes antiinflamatórios
DE69120670D1 (de)	1996-08-08	Lipo-oligosaccharide als pflanzenspezifisches regulierendes mittel, verfahren zu ihrer herstellung und ihre verwendungen
ATE178334T1 (de)	1999-04-15	Di-lysogangliosidderivate
MX9301667A (es)	1993-11-01	Acidos 7-oxo-7h-pirido(1,2,3-de)(1,4)-benzoxacin-6-carboxilicos y sus esteres y medicamentos que los contienen.
ATE73812T1 (de)	1992-04-15	Thionophosphonsaeureester.
DE60003697D1 (de)	2003-08-07	Aktive marine alkaloiden
IT1247510B (it)	1994-12-17	Composizioni terapeutiche ad attivita' anti-hiv costituite da 2',3'-didesossiadenosina e sostanze inibitrici della adenosina-deaminasi