DK0699680T3 - Oxazologuinolinonderivater, deres fremstilling og deres terapeutiske anvendelse - Google Patents

Oxazologuinolinonderivater, deres fremstilling og deres terapeutiske anvendelse

Info

Publication number: DK0699680T3
Authority: DK; Denmark
Prior art keywords: oxazologuinolinone; derivatives; preparation; therapeutic use; ch2ome
Prior art date: 1994-09-05

Application number

DK95401989T

Other languages

English (en)

Inventor

Samir Jegham

Jean Jacques Koenig

Philippe Burnier

Lydia Zard

Frederic Puech

Original Assignee

Sanofi Synthelabo

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1994-09-05

Filing date

1995-09-01

Publication date

2000-08-21

1995-09-01 Application filed by Sanofi Synthelabo filed Critical Sanofi Synthelabo

2000-08-21 Application granted granted Critical

2000-08-21 Publication of DK0699680T3 publication Critical patent/DK0699680T3/da

Links

230000001225 therapeutic effect Effects 0.000 title 1
IYFPFSMWFRSRCD-UHFFFAOYSA-N 3,3a,4,5-tetrahydro-[1,3]oxazolo[3,4-a]quinolin-1-one Chemical compound C1=CC=C2N3C(=O)OCC3CCC2=C1 IYFPFSMWFRSRCD-UHFFFAOYSA-N 0.000 abstract 1
125000000051 benzyloxy group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])O* 0.000 abstract 1
CBOIHMRHGLHBPB-UHFFFAOYSA-N hydroxymethyl Chemical compound O[CH2] CBOIHMRHGLHBPB-UHFFFAOYSA-N 0.000 abstract 1
125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
125000000391 vinyl group Chemical group [H]C([*])=C([H])[H] 0.000 abstract 1
229920002554 vinyl polymer Polymers 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D498/04—Ortho-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/26—Psychostimulants, e.g. nicotine, cocaine
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

Health & Medical Sciences (AREA)
Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Neurosurgery (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
Life Sciences & Earth Sciences (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Chemical Kinetics & Catalysis (AREA)
Psychiatry (AREA)
Pain & Pain Management (AREA)
Anesthesiology (AREA)
Hospice & Palliative Care (AREA)
Psychology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Micro-Organisms Or Cultivation Processes Thereof (AREA)
Quinoline Compounds (AREA)

DK95401989T 1994-09-05 1995-09-01 Oxazologuinolinonderivater, deres fremstilling og deres terapeutiske anvendelse DK0699680T3 (da)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
FR9410600A FR2724171B1 (fr)	1994-09-05	1994-09-05	Derives de 3,3a,4,5-tetrahydro-1h-oxazolo(3,4-a)quinolein-1-one, leur preparation et leur application en therapeutique

Publications (1)

Publication Number	Publication Date
DK0699680T3 true DK0699680T3 (da)	2000-08-21

Family

ID=9466686

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK95401989T DK0699680T3 (da)	1994-09-05	1995-09-01	Oxazologuinolinonderivater, deres fremstilling og deres terapeutiske anvendelse

Country Status (27)

Country	Link
US (1)	US5641785A (da)
EP (1)	EP0699680B1 (da)
JP (1)	JP4225585B2 (da)
KR (1)	KR100392523B1 (da)
CN (1)	CN1055472C (da)
AT (1)	ATE190311T1 (da)
AU (1)	AU687591B2 (da)
CA (1)	CA2157427C (da)
CZ (1)	CZ286128B6 (da)
DE (1)	DE69515402T2 (da)
DK (1)	DK0699680T3 (da)
ES (1)	ES2145886T3 (da)
FI (1)	FI110945B (da)
FR (1)	FR2724171B1 (da)
GR (1)	GR3033554T3 (da)
HU (1)	HU218587B (da)
IL (1)	IL115276A (da)
NO (1)	NO306617B1 (da)
NZ (1)	NZ272920A (da)
PL (1)	PL184412B1 (da)
PT (1)	PT699680E (da)
RU (1)	RU2141482C1 (da)
SI (1)	SI0699680T1 (da)
SK (1)	SK281867B6 (da)
TW (1)	TW356467B (da)
UA (1)	UA41916C2 (da)
ZA (1)	ZA957414B (da)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
EP1078632A1 (en) *	1999-08-16	2001-02-28	Sanofi-Synthelabo	Use of monoamine oxydase inhibitors for the manufacture of drugs intended for the treatment of obesity
US7553967B2 (en) *	2004-03-12	2009-06-30	Wyeth	1,2-Dihydroquinoline derivatives and method for using the same to treat HIV infections
MY147757A (en) *	2007-03-09	2013-01-15	Sanofi Aventis	Substituted dihydro and tetrahydro oxazolopyrimidinones, preparation and use thereof
RU2366430C2 (ru)	2007-05-23	2009-09-10	Виктор Иванович Рощин	Ингибиторы моноаминооксидазы, лекарственное средство и фармацевтическая композиция
AR078171A1 (es)	2009-09-15	2011-10-19	Sanofi Aventis	Dihidrobenzocicloalquiloximetil-oxazolopirimidinonas sustituidas, preparacion y uso de las mismas
CN105949120B (zh) *	2016-05-27	2018-07-24	广东工业大学	一种四齿螯合型单喹啉衍生物及其制备方法和作为神经退行性疾病的金属离子调节剂的应用

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
EP0128120A3 (de) *	1983-06-02	1985-11-13	Ciba-Geigy Ag	Trisubstituierte Oxazolidinone
FR2624861B1 (fr) *	1987-12-21	1990-06-01	Delalande Sa	Carbamates tricycliques, leur procede de preparation et leur application en therapeutique
ES2013391A6 (es) *	1989-02-08	1990-05-01	Consejo Superior Investigacion	Procedimiento para la preparacion de derivados acetilenicos y alenicos de 2-aminometil -5-metoxiindoles.
JPH04295470A (ja) *	1991-03-22	1992-10-20	Wakamoto Pharmaceut Co Ltd	モノアミンオキシダーゼ−ｂ酵素阻害活性を有する１，２，４−オキサジアゾール誘導体及びその製造法

1994
- 1994-09-05 FR FR9410600A patent/FR2724171B1/fr not_active Expired - Lifetime
1995
- 1995-09-01 CA CA2157427A patent/CA2157427C/en not_active Expired - Lifetime
- 1995-09-01 US US08/523,508 patent/US5641785A/en not_active Expired - Lifetime
- 1995-09-01 EP EP95401989A patent/EP0699680B1/fr not_active Expired - Lifetime
- 1995-09-01 ES ES95401989T patent/ES2145886T3/es not_active Expired - Lifetime
- 1995-09-01 AT AT95401989T patent/ATE190311T1/de active
- 1995-09-01 PT PT95401989T patent/PT699680E/pt unknown
- 1995-09-01 SI SI9530413T patent/SI0699680T1/xx unknown
- 1995-09-01 DE DE69515402T patent/DE69515402T2/de not_active Expired - Lifetime
- 1995-09-01 DK DK95401989T patent/DK0699680T3/da active
- 1995-09-02 TW TW084109192A patent/TW356467B/zh not_active IP Right Cessation
- 1995-09-04 HU HU9502578A patent/HU218587B/hu unknown
- 1995-09-04 SK SK1089-95A patent/SK281867B6/sk not_active IP Right Cessation
- 1995-09-04 ZA ZA957414A patent/ZA957414B/xx unknown
- 1995-09-04 AU AU30415/95A patent/AU687591B2/en not_active Expired
- 1995-09-04 PL PL95310273A patent/PL184412B1/pl unknown
- 1995-09-04 CN CN95117143A patent/CN1055472C/zh not_active Expired - Lifetime
- 1995-09-04 UA UA95094019A patent/UA41916C2/uk unknown
- 1995-09-04 RU RU95114741A patent/RU2141482C1/ru active
- 1995-09-04 NZ NZ272920A patent/NZ272920A/en not_active IP Right Cessation
- 1995-09-04 CZ CZ19952262A patent/CZ286128B6/cs not_active IP Right Cessation
- 1995-09-04 NO NO953458A patent/NO306617B1/no not_active IP Right Cessation
- 1995-09-04 KR KR1019950028714A patent/KR100392523B1/ko not_active Expired - Lifetime
- 1995-09-04 JP JP22646295A patent/JP4225585B2/ja not_active Expired - Lifetime
- 1995-09-04 FI FI954141A patent/FI110945B/fi not_active IP Right Cessation
- 1995-09-12 IL IL11527695A patent/IL115276A/en not_active IP Right Cessation
2000
- 2000-05-31 GR GR20000401246T patent/GR3033554T3/el unknown

Also Published As

Publication number	Publication date
JP4225585B2 (ja)	2009-02-18
HU218587B (hu)	2000-10-28
KR100392523B1 (ko)	2003-11-12
SK281867B6 (sk)	2001-08-06
RU2141482C1 (ru)	1999-11-20
FR2724171A1 (fr)	1996-03-08
HU9502578D0 (en)	1995-11-28
SK108995A3 (en)	1996-06-05
NZ272920A (en)	1998-03-25
KR960010648A (ko)	1996-04-20
IL115276A0 (en)	1996-01-19
TW356467B (en)	1999-04-21
UA41916C2 (uk)	2001-10-15
NO953458L (no)	1996-03-06
PT699680E (pt)	2000-08-31
PL184412B1 (pl)	2002-10-31
IL115276A (en)	1998-12-06
CZ226295A3 (en)	1996-03-13
US5641785A (en)	1997-06-24
CN1128763A (zh)	1996-08-14
CZ286128B6 (cs)	2000-01-12
AU687591B2 (en)	1998-02-26
AU3041595A (en)	1996-03-21
ATE190311T1 (de)	2000-03-15
CN1055472C (zh)	2000-08-16
CA2157427C (en)	2010-06-01
EP0699680A1 (fr)	1996-03-06
DE69515402T2 (de)	2000-10-19
NO953458D0 (no)	1995-09-04
SI0699680T1 (en)	2000-10-31
FR2724171B1 (fr)	1997-01-03
ZA957414B (en)	1996-04-15
DE69515402D1 (de)	2000-04-13
GR3033554T3 (en)	2000-09-29
FI954141A0 (fi)	1995-09-04
JPH0899881A (ja)	1996-04-16
FI110945B (fi)	2003-04-30
HUT73435A (en)	1996-07-29
CA2157427A1 (en)	1996-03-06
ES2145886T3 (es)	2000-07-16
NO306617B1 (no)	1999-11-29
FI954141L (fi)	1996-03-06
EP0699680B1 (fr)	2000-03-08
HK1013652A1 (en)	1999-09-03
PL310273A1 (en)	1996-03-18

Publication	Publication Date	Title
BR9103784A (pt)	1992-05-19	Composicao de tratamento de cabelo
PT889886E (pt)	2003-02-28	Novas fenantridinas substituidas na posicao 6
ATE226201T1 (de)	2002-11-15	Substituierte pyridylpyrazole
ATE219938T1 (de)	2002-07-15	Neue 4-arylpiperazine und 4-arylpiperidine
PT536515E (pt)	2002-05-31	Novas 7-substituido-9-(amino substitido)-6-desmetil-6-desoxitetraciclinas
SE8107537L (sv)	1982-06-23	Nya derivat av heterocykliska aminoalcoyler, deras framstellningssett och deras terapeutiska anvendning
IL122123A0 (en)	1998-04-05	Atherosclerosis treatment
FI925849A0 (fi)	1992-12-23	Tiazolidinfoereningar, deras framstaellning och terapeutiska anvaendningar
FI930977A0 (fi)	1993-03-04	Taxanderivat, deras framstaellning och onkologiska anvaendning
FI925848A0 (fi)	1992-12-23	Tizolidinfoereningar, som innehaoller en kinogrupp, deras framstaellning och terapeutiska anvaendningar
DE69802249D1 (de)	2001-12-06	Neue N-Aryl-2-hydroxy-alkylamide
NO953458L (no)	1996-03-06	Oksazolkinolinonderivater, deres fremstilling og terapeutiske anvendelse
FI932683A0 (fi)	1993-06-11	Skoetselmedel foer haorda och mjuka kontaktlinser
DE69606337D1 (de)	2000-03-02	Trizyklische Derivate, ihre Herstellung, ihre Verwendung zur Herstellung von optisch aktivem oder racemischem Colchizin, Thiocolchizin, dessen Analoge oder Derivate, und Intermediate
DE69033342D1 (de)	1999-12-09	Etoposidanaloge
NO305399B1 (no)	1999-05-25	2,3-dihydroksypropyl 2-(1-oksoalkyl)amino-2-deoksoglucopyranosider, deres fremstilling og anvendelse
ATE124686T1 (de)	1995-07-15	Phenylalkylamine und diese enthaltende fungizide.
FR2716198B1 (fr)	1996-04-19	Facteur cytotoxique tel qu'associé à la sclérose en plaques, sa détection et sa quantification.
FI912269A0 (fi)	1991-05-10	3'-deamino - 4'deoxi - 4'-amino- 8 -fluorantracykliner och framstaellningsfoerfaranden foer dessa.
FR2682378B1 (fr)	1995-04-07	Nouveaux derives de l'acide fluoroquinoleine carboxylique-3 et leur preparation.
DE3865521D1 (de)	1991-11-21	4-methyl-4-phenyl-1-pentanale, deren herstellung und verwendung als riechstoffe.
ATE12645T1 (de)	1985-04-15	Phenylethylthiazolderivate, ihre herstellung und ihre anwendung in der therapeutik.
SU1690242A1 (ru)	1999-08-10	Антифидант
SU1427799A1 (ru)	1999-07-10	ПРОИЗВОДНЫЕ 9,11-(β,β-ДИМЕТИЛТРИМЕТИЛЕН)-ТИАХИНО-4'-ТЕТРАКАРБОЦИАНИНОВ В КАЧЕСТВЕ СПЕКТРАЛЬНЫХ СЕНСИБИЛИЗАТОРОВ БРОМЙОДСЕРЕБРЯНЫХ ФОТОГРАФИЧЕСКИХ ЭМУЛЬСИЙ
ITMI912104A1 (it)	1993-01-29	Poliglucosidi da idrossialchilsorbitolo