DK0703907T3 - Fremgangsmåde til fremstilling af terapeutisk aktive taxoider - Google Patents

Fremgangsmåde til fremstilling af terapeutisk aktive taxoider

Info

Publication number: DK0703907T3
Authority: DK; Denmark
Prior art keywords: preparation; therapeutically active; taxoids; active taxoids; iii
Prior art date: 1993-06-16

Application number

DK94919710.7T

Other languages

English (en)

Inventor

Jean-Dominique Bourzat

Alain Commercon

Original Assignee

Rhone Poulenc Rorer Sa

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1993-06-16

Filing date

1994-06-15

Publication date

1998-03-23

1994-06-15 Application filed by Rhone Poulenc Rorer Sa filed Critical Rhone Poulenc Rorer Sa

1998-03-23 Application granted granted Critical

1998-03-23 Publication of DK0703907T3 publication Critical patent/DK0703907T3/da

Links

OVMSOCFBDVBLFW-VHLOTGQHSA-N 5beta,20-epoxy-1,7beta,13alpha-trihydroxy-9-oxotax-11-ene-2alpha,4alpha,10beta-triyl 4,10-diacetate 2-benzoate Chemical compound O([C@@H]1[C@@]2(C[C@H](O)C(C)=C(C2(C)C)[C@H](C([C@]2(C)[C@@H](O)C[C@H]3OC[C@]3([C@H]21)OC(C)=O)=O)OC(=O)C)O)C(=O)C1=CC=CC=C1 OVMSOCFBDVBLFW-VHLOTGQHSA-N 0.000 abstract 2
KNWCDYSKJSREAQ-UHFFFAOYSA-N 1,3-oxazolidine-2-carboxylic acid Chemical compound OC(=O)C1NCCO1 KNWCDYSKJSREAQ-UHFFFAOYSA-N 0.000 abstract 1
239000002253 acid Substances 0.000 abstract 1
150000008065 acid anhydrides Chemical class 0.000 abstract 1
229930014667 baccatin III Natural products 0.000 abstract 1
150000004820 halides Chemical class 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
- C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
- C07D263/04—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D305/00—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms
- C07D305/14—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms condensed with carbocyclic rings or ring systems

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Epoxy Compounds (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)

DK94919710.7T 1993-06-16 1994-06-15 Fremgangsmåde til fremstilling af terapeutisk aktive taxoider DK0703907T3 (da)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
FR9307240A FR2706457B1 (fr)	1993-06-16	1993-06-16	Procédé de préparation d'un acide oxazolidinecarboxylique utile pour préparer des taxoïdes thérapeutiquement actifs.

Publications (1)

Publication Number	Publication Date
DK0703907T3 true DK0703907T3 (da)	1998-03-23

Family

ID=9448182

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK94919710.7T DK0703907T3 (da)	1993-06-16	1994-06-15	Fremgangsmåde til fremstilling af terapeutisk aktive taxoider

Country Status (23)

Country	Link
US (2)	US6444825B1 (da)
EP (1)	EP0703907B1 (da)
JP (1)	JPH09500370A (da)
KR (1)	KR960703118A (da)
AT (1)	ATE156819T1 (da)
AU (1)	AU678585B2 (da)
CA (1)	CA2165328A1 (da)
CZ (1)	CZ284051B6 (da)
DE (1)	DE69404991T2 (da)
DK (1)	DK0703907T3 (da)
ES (1)	ES2107237T3 (da)
FI (1)	FI956025A0 (da)
FR (1)	FR2706457B1 (da)
GR (1)	GR3024534T3 (da)
HU (1)	HUT73972A (da)
NO (1)	NO955112D0 (da)
NZ (1)	NZ268037A (da)
PL (1)	PL312212A1 (da)
RU (1)	RU2128652C1 (da)
SK (1)	SK156995A3 (da)
WO (1)	WO1994029284A1 (da)
YU (1)	YU37594A (da)
ZA (1)	ZA943994B (da)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5973160A (en)	1992-12-23	1999-10-26	Poss; Michael A.	Methods for the preparation of novel sidechain-bearing taxanes
CA2170661A1 (en)	1995-03-22	1996-09-23	John K. Thottathil	Novel methods for the preparation of taxanes using oaxzolidine intermediates
NZ332475A (en) *	1996-05-08	2000-05-26	Upjohn Co	silylated baccatin derivatives, 3-(substituted amino)-3-phenyl-(2R,3S)-isoserinate derivatives, the oxazolidine ester thereof and other immediates used to prepare baccatin derivatives
KR100225535B1 (ko) *	1996-08-27	1999-10-15	정지석	파클리탁셀의 제조방법
MXPA03002494A (es) *	2000-09-22	2004-05-24	Bristol Myers Squibb Co	Metodo para reducir toxicidad de quimio terapias combinadas.
WO2006055837A2 (en) *	2004-11-19	2006-05-26	Dr. Reddy's Laboratories Ltd.	Process for preparing oxazolidine derivatives
CA2599888C (en)	2005-03-31	2010-06-15	Bioxel Pharma Inc.	Preparation of taxanes from 9-dihydro-13-acetylbaccatin iii

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4240987A (en) *	1979-10-29	1980-12-23	Xerox Corporation	Chemical process
FR2629819B1 (fr) *	1988-04-06	1990-11-16	Rhone Poulenc Sante	Procede de preparation de derives de la baccatine iii et de la desacetyl-10 baccatine iii
MX9102128A (es) *	1990-11-23	1992-07-08	Rhone Poulenc Rorer Sa	Derivados de taxano,procedimiento para su preparacion y composicion farmaceutica que los contiene
FR2696458B1 (fr) *	1992-10-05	1994-11-10	Rhone Poulenc Rorer Sa	Procédé de préparation de dérivés du taxane.
FR2696459B1 (fr) *	1992-10-05	1994-11-25	Rhone Poulenc Rorer Sa	Procédé de préparation de dérivés du taxane.
FR2696460B1 (fr) *	1992-10-05	1994-11-25	Rhone Poulenc Rorer Sa	Procédé de préparation de dérivés du taxane.
FR2698361B1 (fr) *	1992-11-20	1995-01-13	Rhone Poulenc Rorer Sa	Procédé de préparation d'un acide oxazolidine-1,3 carboxylique-5.
FR2698871B1 (fr) *	1992-12-09	1995-02-24	Rhone Poulenc Rorer Sa	Nouveau taxoïdes, leur préparation et les compositions pharmaceutiques qui les contiennent.
FR2702212B1 (fr) *	1993-03-02	1995-04-07	Rhone Poulenc Rorer Sa	Nouveaux taxoïdes, leur préparation et les compositions pharmaceutiques qui les contiennent.

1993
- 1993-06-16 FR FR9307240A patent/FR2706457B1/fr not_active Expired - Fee Related
1994
- 1994-06-07 ZA ZA943994A patent/ZA943994B/xx unknown
- 1994-06-15 JP JP7501433A patent/JPH09500370A/ja active Pending
- 1994-06-15 DE DE69404991T patent/DE69404991T2/de not_active Expired - Fee Related
- 1994-06-15 ES ES94919710T patent/ES2107237T3/es not_active Expired - Lifetime
- 1994-06-15 US US08/564,345 patent/US6444825B1/en not_active Expired - Lifetime
- 1994-06-15 RU RU96101137A patent/RU2128652C1/ru active
- 1994-06-15 PL PL94312212A patent/PL312212A1/xx unknown
- 1994-06-15 AU AU70762/94A patent/AU678585B2/en not_active Ceased
- 1994-06-15 DK DK94919710.7T patent/DK0703907T3/da active
- 1994-06-15 SK SK1569-95A patent/SK156995A3/sk unknown
- 1994-06-15 CZ CZ953292A patent/CZ284051B6/cs unknown
- 1994-06-15 AT AT94919710T patent/ATE156819T1/de not_active IP Right Cessation
- 1994-06-15 NZ NZ268037A patent/NZ268037A/en unknown
- 1994-06-15 EP EP94919710A patent/EP0703907B1/fr not_active Expired - Lifetime
- 1994-06-15 KR KR1019950705715A patent/KR960703118A/ko not_active Withdrawn
- 1994-06-15 HU HU9503611A patent/HUT73972A/hu unknown
- 1994-06-15 CA CA002165328A patent/CA2165328A1/fr not_active Abandoned
- 1994-06-15 WO PCT/FR1994/000713 patent/WO1994029284A1/fr not_active Ceased
- 1994-06-16 YU YU37594A patent/YU37594A/sh unknown
1995
- 1995-12-14 FI FI956025A patent/FI956025A0/fi unknown
- 1995-12-15 NO NO955112A patent/NO955112D0/no unknown
1997
- 1997-08-26 GR GR970400040T patent/GR3024534T3/el unknown
1998
- 1998-04-02 US US09/053,486 patent/US6043375A/en not_active Expired - Fee Related

Also Published As

Publication number	Publication date
CZ284051B6 (cs)	1998-07-15
SK156995A3 (en)	1996-06-05
JPH09500370A (ja)	1997-01-14
WO1994029284A1 (fr)	1994-12-22
DE69404991D1 (de)	1997-09-18
US6043375A (en)	2000-03-28
FI956025A7 (fi)	1995-12-14
CZ329295A3 (en)	1996-03-13
HUT73972A (en)	1996-10-28
AU678585B2 (en)	1997-06-05
YU37594A (sh)	1997-03-07
FR2706457A1 (fr)	1994-12-23
FR2706457B1 (fr)	1995-07-28
ZA943994B (en)	1995-02-03
AU7076294A (en)	1995-01-03
CA2165328A1 (fr)	1994-12-22
ATE156819T1 (de)	1997-08-15
KR960703118A (ko)	1996-06-19
NO955112L (no)	1995-12-15
EP0703907A1 (fr)	1996-04-03
DE69404991T2 (de)	1998-01-22
RU2128652C1 (ru)	1999-04-10
FI956025A0 (fi)	1995-12-14
NZ268037A (en)	1997-11-24
EP0703907B1 (fr)	1997-08-13
US6444825B1 (en)	2002-09-03
GR3024534T3 (en)	1997-12-31
ES2107237T3 (es)	1997-11-16
NO955112D0 (no)	1995-12-15
HU9503611D0 (en)	1996-02-28
PL312212A1 (en)	1996-04-01

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