DK0708776T3 - Antiallergiske imidazoazepiner - Google Patents
Antiallergiske imidazoazepinerInfo
- Publication number
- DK0708776T3 DK0708776T3 DK94924248T DK94924248T DK0708776T3 DK 0708776 T3 DK0708776 T3 DK 0708776T3 DK 94924248 T DK94924248 T DK 94924248T DK 94924248 T DK94924248 T DK 94924248T DK 0708776 T3 DK0708776 T3 DK 0708776T3
- Authority
- DK
- Denmark
- Prior art keywords
- pct
- formula
- radical
- 6alkyl
- imidazoazepines
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/14—Decongestants or antiallergics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/16—Otologicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains three hetero rings
- C07D487/14—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/12—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains three hetero rings
- C07D491/14—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/12—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains three hetero rings
- C07D495/14—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
- C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
- C07D513/04—Ortho-condensed systems
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Pulmonology (AREA)
- Immunology (AREA)
- Ophthalmology & Optometry (AREA)
- Dermatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Plural Heterocyclic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP93202154 | 1993-07-13 | ||
| PCT/EP1994/002287 WO1995002600A1 (en) | 1993-07-13 | 1994-07-06 | Antiallergic imidazoazepines |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK0708776T3 true DK0708776T3 (da) | 2001-05-21 |
Family
ID=8213997
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK94924248T DK0708776T3 (da) | 1993-07-13 | 1994-07-06 | Antiallergiske imidazoazepiner |
Country Status (18)
| Country | Link |
|---|---|
| US (1) | US5674866A (de) |
| EP (1) | EP0708776B1 (de) |
| JP (1) | JP3681388B2 (de) |
| KR (1) | KR100346802B1 (de) |
| CN (1) | CN1042228C (de) |
| AT (1) | ATE198480T1 (de) |
| AU (1) | AU679102B2 (de) |
| DE (1) | DE69426528T2 (de) |
| DK (1) | DK0708776T3 (de) |
| ES (1) | ES2155092T3 (de) |
| FI (1) | FI960157A7 (de) |
| GR (1) | GR3035629T3 (de) |
| NO (1) | NO312837B1 (de) |
| NZ (1) | NZ271071A (de) |
| PL (1) | PL177224B1 (de) |
| PT (1) | PT708776E (de) |
| RU (1) | RU2133249C1 (de) |
| WO (1) | WO1995002600A1 (de) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TW382017B (en) | 1995-12-27 | 2000-02-11 | Janssen Pharmaceutica Nv | 1-(1,2-disubstituted piperidinyl)-4-(fused imidazole)-piperidine derivatives |
| TW527186B (en) | 1996-03-19 | 2003-04-11 | Janssen Pharmaceutica Nv | Fused imidazole derivatives as multidrug resistance modulators |
| NZ333399A (en) | 1997-12-24 | 2000-05-26 | Sankyo Co | Cyclooxygenase-2 inhibitors (COX-2) for the prevention and treatment of tumors, cachexia and tumor-metastasis |
| AU2001290743A1 (en) * | 2000-09-14 | 2002-03-26 | Ortho-Mcneil Pharmaceutical, Inc. | Solid salt forms of n-(2-(4-(2-(1-methylethoxy)phenyl)-1-piperazinyl)ethyl)-2-oxo-1-piperidineacetamide |
| CN100491378C (zh) | 2001-06-12 | 2009-05-27 | 詹森药业有限公司 | 新的取代四环咪唑衍生物,其制备方法,包含它们的药物组合物及它们作为药物的用途 |
| KR20010100067A (ko) * | 2001-08-30 | 2001-11-14 | 김권 | 전분이 결합된 생분해성 수지 조성물 |
| TWI290140B (en) * | 2003-08-25 | 2007-11-21 | Schering Corp | 2-Substituted benzimidazole derivatives as selective melanin concentrating hormone receptor antagonists for thr treatment of obesity and related disorders |
| DE602006016244D1 (de) | 2005-03-08 | 2010-09-30 | Janssen Pharmaceutica Nv | Diazaspiro-ä4,4ü-nonanderivate als neurokinin-(nk1)-antagonisten |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2534257A1 (fr) * | 1982-10-12 | 1984-04-13 | Roussel Uclaf | Nouveaux derives de la 6-amino 7-hydroxy 4,5,6,7-tetrahydro-imidazo/4,5,1-j-k/ /1/ benzazepin-2(1h)-one, leurs sels, application a titre de medicaments, compositions les renfermant et un intermediaire |
| US4650804A (en) * | 1984-03-30 | 1987-03-17 | Fujisawa Pharmaceutical Co., Ltd. | Quinolizinone compounds and pharmaceutical composition comprising the same, useful as anti-ulcerative and anti-allergic agents |
| SU1273361A1 (ru) * | 1985-07-09 | 1986-11-30 | Новокузнецкий научно-исследовательский химико-фармацевтический институт | Производные @ 1,4 @ диазепино @ 2,3- @ индолов |
| US4826853A (en) * | 1986-10-31 | 1989-05-02 | Schering Corporation | 6,11-Dihydro-11-(N-substituted-4-piperidylidene)-5H-benzo(5,6)cyclohepta(1,2-B)pyridines and compositions and methods of use |
| DE3637255A1 (de) * | 1986-11-03 | 1988-05-05 | Metallgesellschaft Ag | Verfahren zum aufarbeiten von altoel |
| EP0339978B1 (de) * | 1988-04-28 | 1996-08-21 | Schering Corporation | Kondensierte polyzyklische Verbindungen, Zusammenstellungen, Verfahren zur Herstellung und deren Anwendung als PAF-antagonistische, antihistaminische und/oder anti-inflammatorische Agenzien |
| US5393753A (en) * | 1990-10-10 | 1995-02-28 | Schering Corporation | Substituted imidazobenzazepines |
| PH31566A (en) * | 1990-10-10 | 1998-11-03 | Schering Corp | Pyridine and pyridine n-oxide derivatives for diaryl methyl piperidines or piperazines and compositions and methods of use thereof. |
| IL101851A (en) * | 1991-06-13 | 1996-05-14 | Janssen Pharmaceutica Nv | 10-(4-piperidinyl- and piperidinylidene)-imidazo [1,2-a] (pyrrolo thieno or furano) [2,3] azepine derivatives their preparation and pharmaceutical compositions containing them and certain novel intermediates therefor |
| IL101850A (en) * | 1991-06-13 | 1996-01-31 | Janssen Pharmaceutica Nv | 11-(4-Piperidinyl)-imidazo (2,1-b) (3) benzazepine derivatives their preparation and pharmaceutical compositions containing them |
-
1994
- 1994-07-06 EP EP94924248A patent/EP0708776B1/de not_active Expired - Lifetime
- 1994-07-06 JP JP50434095A patent/JP3681388B2/ja not_active Expired - Fee Related
- 1994-07-06 ES ES94924248T patent/ES2155092T3/es not_active Expired - Lifetime
- 1994-07-06 DE DE69426528T patent/DE69426528T2/de not_active Expired - Fee Related
- 1994-07-06 AU AU74583/94A patent/AU679102B2/en not_active Ceased
- 1994-07-06 PL PL94312576A patent/PL177224B1/pl not_active IP Right Cessation
- 1994-07-06 AT AT94924248T patent/ATE198480T1/de not_active IP Right Cessation
- 1994-07-06 PT PT94924248T patent/PT708776E/pt unknown
- 1994-07-06 DK DK94924248T patent/DK0708776T3/da active
- 1994-07-06 WO PCT/EP1994/002287 patent/WO1995002600A1/en not_active Ceased
- 1994-07-06 KR KR1019950705670A patent/KR100346802B1/ko not_active Expired - Fee Related
- 1994-07-06 US US08/557,131 patent/US5674866A/en not_active Expired - Fee Related
- 1994-07-06 FI FI960157A patent/FI960157A7/fi unknown
- 1994-07-06 NZ NZ271071A patent/NZ271071A/en unknown
- 1994-07-06 RU RU96102595A patent/RU2133249C1/ru not_active IP Right Cessation
- 1994-07-06 CN CN94192768A patent/CN1042228C/zh not_active Expired - Fee Related
-
1995
- 1995-12-06 NO NO19954938A patent/NO312837B1/no unknown
-
2001
- 2001-03-23 GR GR20010400474T patent/GR3035629T3/el not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| DE69426528D1 (de) | 2001-02-08 |
| ATE198480T1 (de) | 2001-01-15 |
| AU7458394A (en) | 1995-02-13 |
| JP3681388B2 (ja) | 2005-08-10 |
| ES2155092T3 (es) | 2001-05-01 |
| NO954938L (no) | 1995-12-06 |
| GR3035629T3 (en) | 2001-06-29 |
| JPH08512328A (ja) | 1996-12-24 |
| FI960157A0 (fi) | 1996-01-12 |
| US5674866A (en) | 1997-10-07 |
| FI960157L (fi) | 1996-01-12 |
| EP0708776B1 (de) | 2001-01-03 |
| FI960157A7 (fi) | 1996-01-12 |
| CN1042228C (zh) | 1999-02-24 |
| RU2133249C1 (ru) | 1999-07-20 |
| CN1126995A (zh) | 1996-07-17 |
| PL312576A1 (en) | 1996-04-29 |
| NO954938D0 (no) | 1995-12-06 |
| EP0708776A1 (de) | 1996-05-01 |
| NZ271071A (en) | 1996-08-27 |
| WO1995002600A1 (en) | 1995-01-26 |
| AU679102B2 (en) | 1997-06-19 |
| PL177224B1 (pl) | 1999-10-29 |
| DE69426528T2 (de) | 2001-08-23 |
| PT708776E (pt) | 2001-06-29 |
| NO312837B1 (no) | 2002-07-08 |
| KR100346802B1 (ko) | 2002-11-29 |
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