DK0726898T3 - Phenylindolforbindelser - Google Patents

Phenylindolforbindelser

Info

Publication number: DK0726898T3
Authority: DK; Denmark
Prior art keywords: pct; date; sec; phenylindole; pub
Prior art date: 1993-11-01

Application number

DK94931520T

Other languages

English (en)

Inventor

Jens Kristian Perregaard

Ejner Knud Moltzen

Kim Andersen

Klaus Peter Böges

Andre Pernet

Barbara Bopp

Darcy Mulford

Kiyoshi Sakamoto

Henrik Pedersen

Original Assignee

Lundbeck & Co As H

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1993-11-01

Filing date

1994-10-28

Publication date

2001-04-30

1994-10-28 Application filed by Lundbeck & Co As H filed Critical Lundbeck & Co As H

2001-04-30 Application granted granted Critical

2001-04-30 Publication of DK0726898T3 publication Critical patent/DK0726898T3/da

Links

KLLLJCACIRKBDT-UHFFFAOYSA-N 2-phenyl-1H-indole Chemical compound N1C2=CC=CC=C2C=C1C1=CC=CC=C1 KLLLJCACIRKBDT-UHFFFAOYSA-N 0.000 title abstract 2
239000003693 atypical antipsychotic agent Substances 0.000 abstract 1
GZKLJWGUPQBVJQ-UHFFFAOYSA-N sertindole Chemical compound C1=CC(F)=CC=C1N1C2=CC=C(Cl)C=C2C(C2CCN(CCN3C(NCC3)=O)CC2)=C1 GZKLJWGUPQBVJQ-UHFFFAOYSA-N 0.000 abstract 1
229960000652 sertindole Drugs 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/26—Psychostimulants, e.g. nicotine, cocaine
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
Veterinary Medicine (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Psychiatry (AREA)
Heart & Thoracic Surgery (AREA)
Pain & Pain Management (AREA)
Cardiology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Indole Compounds (AREA)
Sewing Machines And Sewing (AREA)
Agricultural Chemicals And Associated Chemicals (AREA)
Polyurethanes Or Polyureas (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)

DK94931520T 1993-11-01 1994-10-28 Phenylindolforbindelser DK0726898T3 (da)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
DK931234A DK123493D0 (da)	1993-11-01	1993-11-01	Compounds
PCT/DK1994/000407 WO1995012591A1 (en)	1993-11-01	1994-10-28	Phenylindole compounds

Publications (1)

Publication Number	Publication Date
DK0726898T3 true DK0726898T3 (da)	2001-04-30

Family

ID=8102507

Family Applications (2)

Application Number	Title	Priority Date	Filing Date
DK931234A DK123493D0 (da)	1993-11-01	1993-11-01	Compounds
DK94931520T DK0726898T3 (da)	1993-11-01	1994-10-28	Phenylindolforbindelser

Family Applications Before (1)

Application Number	Title	Priority Date	Filing Date
DK931234A DK123493D0 (da)	1993-11-01	1993-11-01	Compounds

Country Status (26)

Country	Link
US (1)	US5703087A (da)
EP (1)	EP0726898B1 (da)
JP (1)	JP3898219B2 (da)
KR (1)	KR100350550B1 (da)
CN (1)	CN1134149A (da)
AT (1)	ATE198199T1 (da)
AU (1)	AU683700B2 (da)
CA (1)	CA2175498C (da)
CZ (1)	CZ291403B6 (da)
DE (1)	DE69426462T2 (da)
DK (2)	DK123493D0 (da)
ES (1)	ES2154303T3 (da)
FI (1)	FI116623B (da)
GR (1)	GR3035462T3 (da)
HU (1)	HUT76063A (da)
IL (2)	IL111394A (da)
LV (1)	LV12805B (da)
NO (1)	NO309038B1 (da)
NZ (1)	NZ275086A (da)
PL (1)	PL176391B1 (da)
PT (1)	PT726898E (da)
RU (1)	RU2156249C2 (da)
SI (1)	SI0726898T1 (da)
SK (1)	SK281761B6 (da)
WO (1)	WO1995012591A1 (da)
ZA (1)	ZA948589B (da)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US6489341B1 (en)	1999-06-02	2002-12-03	Sepracor Inc.	Methods for the treatment of neuroleptic and related disorders using sertindole derivatives
JP2003509509A (ja)	1999-09-09	2003-03-11	ハー・ルンドベック・アクチエゼルスカベット	５−アミノアルキル及び５−アミノカルボニル置換されたインドール類
US20070212412A1 (en) *	2005-09-08	2007-09-13	H. Lundbeck A/S	Stable solid formulation of sertindole
TW200821296A (en) *	2006-06-01	2008-05-16	Lundbeck & Co As H	Use of sertindole for the preventive treatment of suicidal behaviour
EP2509961B1 (en) *	2009-12-11	2016-03-09	Autifony Therapeutics Limited	Imidazolidinedione derivatives
EP2582698B1 (en)	2010-06-16	2016-09-14	Vitae Pharmaceuticals, Inc.	Substituted 5-,6- and 7-membered heterocycles, medicaments containing such compounds, and their use
KR101862375B1 (ko)	2010-12-06	2018-05-29	오티포니 세라피틱스 리미티드	Kv3 억제제로서 유용한 하이단토인 유도체
US9193704B2 (en)	2011-06-07	2015-11-24	Autifony Therapeutics Limited	Hydantoin derivatives as KV3 inhibitors
PL2788339T3 (pl) *	2011-12-06	2016-09-30		Pochodne hydantoiny przydatne jako inhibitory KV3
CN104334547B (zh)	2012-05-22	2017-06-06	奥蒂福尼疗法有限公司	作为kv3抑制剂的三唑类
JP2015517563A (ja)	2012-05-22	2015-06-22	アウトイフオンイトヘラペウトイクスリミテッド	Ｋｖ３阻害剤としてのヒダントイン誘導体

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
IE58370B1 (en) *	1985-04-10	1993-09-08	Lundbeck & Co As H	Indole derivatives
GB8908085D0 (en) *	1989-04-11	1989-05-24	Lundbeck & Co As H	New therapeutic use
DK152090D0 (da) *	1990-06-22	1990-06-22	Lundbaek A S H	Piperidylsubstituerede indolderivater

1993
- 1993-11-01 DK DK931234A patent/DK123493D0/da not_active Application Discontinuation
1994
- 1994-10-25 IL IL11139494A patent/IL111394A/en not_active IP Right Cessation
- 1994-10-25 IL IL11139594A patent/IL111395A/xx not_active IP Right Cessation
- 1994-10-28 CN CN94193987A patent/CN1134149A/zh active Pending
- 1994-10-28 DE DE69426462T patent/DE69426462T2/de not_active Expired - Fee Related
- 1994-10-28 WO PCT/DK1994/000407 patent/WO1995012591A1/en not_active Ceased
- 1994-10-28 CA CA002175498A patent/CA2175498C/en not_active Expired - Fee Related
- 1994-10-28 US US08/635,905 patent/US5703087A/en not_active Expired - Fee Related
- 1994-10-28 PL PL94314181A patent/PL176391B1/pl not_active IP Right Cessation
- 1994-10-28 AU AU80577/94A patent/AU683700B2/en not_active Ceased
- 1994-10-28 KR KR1019960702237A patent/KR100350550B1/ko not_active Expired - Fee Related
- 1994-10-28 DK DK94931520T patent/DK0726898T3/da active
- 1994-10-28 SI SI9430356T patent/SI0726898T1/xx unknown
- 1994-10-28 SK SK534-96A patent/SK281761B6/sk not_active IP Right Cessation
- 1994-10-28 CZ CZ19961248A patent/CZ291403B6/cs not_active IP Right Cessation
- 1994-10-28 AT AT94931520T patent/ATE198199T1/de not_active IP Right Cessation
- 1994-10-28 NZ NZ275086A patent/NZ275086A/en not_active IP Right Cessation
- 1994-10-28 EP EP94931520A patent/EP0726898B1/en not_active Expired - Lifetime
- 1994-10-28 JP JP51296895A patent/JP3898219B2/ja not_active Expired - Fee Related
- 1994-10-28 RU RU96110902/04A patent/RU2156249C2/ru not_active IP Right Cessation
- 1994-10-28 HU HU9601144A patent/HUT76063A/hu not_active Application Discontinuation
- 1994-10-28 ES ES94931520T patent/ES2154303T3/es not_active Expired - Lifetime
- 1994-10-28 PT PT94931520T patent/PT726898E/pt unknown
- 1994-11-01 ZA ZA948589A patent/ZA948589B/xx unknown
1996
- 1996-04-30 NO NO961746A patent/NO309038B1/no not_active IP Right Cessation
- 1996-04-30 FI FI961844A patent/FI116623B/fi active IP Right Grant
2001
- 2001-02-22 GR GR20010400296T patent/GR3035462T3/el not_active IP Right Cessation
- 2001-12-20 LV LV010178A patent/LV12805B/xx unknown

Also Published As

Publication number	Publication date
AU8057794A (en)	1995-05-23
EP0726898A1 (en)	1996-08-21
CA2175498A1 (en)	1995-05-11
NO961746L (no)	1996-06-28
SK281761B6 (sk)	2001-07-10
CA2175498C (en)	2005-07-26
CZ124896A3 (en)	1996-09-11
WO1995012591A1 (en)	1995-05-11
KR960705814A (ko)	1996-11-08
PL314181A1 (en)	1996-08-19
JP3898219B2 (ja)	2007-03-28
KR100350550B1 (ko)	2002-12-12
PT726898E (pt)	2001-05-31
FI961844A0 (fi)	1996-04-30
FI116623B (fi)	2006-01-13
HK1013817A1 (en)	1999-09-10
LV12805B (lv)	2002-05-20
IL111394A (en)	1998-08-16
EP0726898B1 (en)	2000-12-20
SK53496A3 (en)	1996-11-06
LV12805A (en)	2002-03-20
IL111395A (en)	1999-06-20
JPH09506083A (ja)	1997-06-17
HU9601144D0 (en)	1996-07-29
DE69426462T2 (de)	2001-04-26
US5703087A (en)	1997-12-30
ATE198199T1 (de)	2001-01-15
SI0726898T1 (en)	2001-04-30
IL111395A0 (en)	1994-12-29
GR3035462T3 (en)	2001-05-31
ES2154303T3 (es)	2001-04-01
NO309038B1 (no)	2000-12-04
CZ291403B6 (cs)	2003-03-12
FI961844L (fi)	1996-04-30
IL111394A0 (en)	1994-12-29
NO961746D0 (no)	1996-04-30
RU2156249C2 (ru)	2000-09-20
HUT76063A (en)	1997-06-30
CN1134149A (zh)	1996-10-23
NZ275086A (en)	1997-10-24
AU683700B2 (en)	1997-11-20
PL176391B1 (pl)	1999-05-31
DK123493D0 (da)	1993-11-01
DE69426462D1 (de)	2001-01-25
ZA948589B (en)	1995-06-26

Publication	Publication Date	Title
GR960100438A (el)	1997-08-29	Νεα παρασιτοκτονα.
ATE229524T1 (de)	2002-12-15	Distamycin a analoga als antitumor- oder antivirale wirkstoffe
ATE185797T1 (de)	1999-11-15	Stilben-derivate verwendbar als cyclooxygenase-2 hemmer
DE69413542D1 (de)	1998-10-29	Perhydroisoindolderivate als substanz p antagonisten
PT100606A (pt)	1993-08-31	Derivados fluoroalcoxibenzilamino de heterociclos contendo azoto
NO962286D0 (no)	1996-06-03	N-substituerte azabicykloalkanderivater som neuroleptika etc.
ES2194202T3 (es)	2003-11-16	Compuestos polimorfos.
DK0772604T3 (da)	1999-11-01	Trialzolforbindelser og deres anvendelse som dopamin-D3-ligander
DK0771197T3 (da)	2003-06-23	Anvendelse af heterocykliske forbindelser som dopamin-D3-ligander
ES2162907T3 (es)	2002-01-16	3-acilaminobenzacepinas.
ATE198199T1 (de)	2001-01-15	Phenylindolverbindungen
DK0833626T3 (da)	2003-06-30	Mono- og disulfosubstituerede anthraquioner og deres anvendelse til behandlingen af knoglematrixforstyrrelser
DK0775113T3 (da)	2001-05-07	N-substituerede azabicycloheptan-derivater som neuroleptika osv.
ATE209205T1 (de)	2001-12-15	Indan-2-mercaptoacetylamid disulfidderivate als enkephalinase inhibitoren
ATE177098T1 (de)	1999-03-15	Mercaptoacetylamid disulfidderivate als enkephalinase und ace inhibitoren