DK0760863T3 - Fremgangsmåde og midler til fremstilling af hyaluronsyre - Google Patents

Fremgangsmåde og midler til fremstilling af hyaluronsyre

Info

Publication number
DK0760863T3
DK0760863T3 DK95921198T DK95921198T DK0760863T3 DK 0760863 T3 DK0760863 T3 DK 0760863T3 DK 95921198 T DK95921198 T DK 95921198T DK 95921198 T DK95921198 T DK 95921198T DK 0760863 T3 DK0760863 T3 DK 0760863T3
Authority
DK
Denmark
Prior art keywords
sup
hyaluronic acid
methods
density
supercapsulated
Prior art date
Application number
DK95921198T
Other languages
English (en)
Inventor
Sten Stahl
Original Assignee
Pharmacia Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pharmacia Ab filed Critical Pharmacia Ab
Application granted granted Critical
Publication of DK0760863T3 publication Critical patent/DK0760863T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • C12N1/205—Bacterial isolates
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/26—Preparation of nitrogen-containing carbohydrates
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00—Microorganisms ; Processes using microorganisms
    • C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
    • C12R2001/46—Streptococcus ; Enterococcus; Lactococcus
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/8215—Microorganisms
    • Y10S435/822—Microorganisms using bacteria or actinomycetales
    • Y10S435/885—Streptococcus

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Biomedical Technology (AREA)
  • Virology (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)
DK95921198T 1994-05-26 1995-05-24 Fremgangsmåde og midler til fremstilling af hyaluronsyre DK0760863T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
SE9401806A SE9401806D0 (sv) 1994-05-26 1994-05-26 Method and means for the production of hyaluronic acid
PCT/SE1995/000585 WO1995033067A1 (en) 1994-05-26 1995-05-24 Method and means for the production of hyaluronic acid

Publications (1)

Publication Number Publication Date
DK0760863T3 true DK0760863T3 (da) 2002-11-25

Family

ID=20394129

Family Applications (1)

Application Number Title Priority Date Filing Date
DK95921198T DK0760863T3 (da) 1994-05-26 1995-05-24 Fremgangsmåde og midler til fremstilling af hyaluronsyre

Country Status (13)

Country Link
US (3) US6090596A (da)
EP (1) EP0760863B1 (da)
JP (1) JP3720361B2 (da)
AT (1) ATE221576T1 (da)
AU (1) AU699404B2 (da)
CA (1) CA2191197C (da)
DE (1) DE69527626T2 (da)
DK (1) DK0760863T3 (da)
ES (1) ES2180639T3 (da)
NZ (1) NZ287583A (da)
PT (1) PT760863E (da)
SE (1) SE9401806D0 (da)
WO (1) WO1995033067A1 (da)

Families Citing this family (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE9401806D0 (sv) * 1994-05-26 1994-05-26 Pharmacia Ab Method and means for the production of hyaluronic acid
US7091008B1 (en) 1994-07-01 2006-08-15 The Board Of Regents Of The University Of Oklahoma Hyaluronan synthase genes and expression thereof in Bacillus hosts
US6951743B2 (en) 1997-10-31 2005-10-04 University Of Oklahoma Board Of Regents Hyaluronan synthase genes and expression thereof in bacillus hosts
US6455304B1 (en) 1994-07-01 2002-09-24 The Board Of Regents Of The University Of Oklahoma Hyaluronate synthase gene and uses thereof
CN101113436B (zh) 1997-10-31 2013-02-06 俄克拉何马大学董事会 透明质酸合酶基因及其应用
ATE284954T1 (de) 1997-10-31 2005-01-15 Univ Oklahoma Hyaluronan synthase gen und seine verwendung
US6987023B2 (en) 1998-04-02 2006-01-17 The Board Of Regents Of The University Of Oklahoma DNA encoding hyaluronan synthase from Pasteurella multocida and methods of use
US7223571B2 (en) 1998-04-02 2007-05-29 The Board Of Regents Of The Universtiy Of Oklahoma Targeted glycosaminoglycan polymers by polymer grafting and methods of making and using same
US20060188966A1 (en) 1998-04-02 2006-08-24 Deangelis Paul L Natural, chimeric and hybrid glycosaminoglycan polymers and methods of making and using same
US7094581B2 (en) 1998-10-26 2006-08-22 The Board Of Regents Of The University Of Oklahoma Hyaluronan synthases and methods of making and using same
US6610666B1 (en) * 1999-11-08 2003-08-26 Bio-Hyos Ab Hyaluronan product and process for manufacturing thereof
US20060094643A1 (en) * 2002-07-03 2006-05-04 Yuri Svirkin Compositions of hyaluronic acid and methods of use
KR100472007B1 (ko) * 2002-08-19 2005-03-10 주식회사 코오롱 히아루론산 생산 균주 및 상기 균주를 이용한 히아루론산 생산방법
US7575914B2 (en) 2002-08-19 2009-08-18 Kolon Life Science, Inc. Microorganism producing hyaluronic acid and purification method of hyaluronic acid
US6946551B2 (en) 2003-03-12 2005-09-20 New Life Resources, Llc Preparation of hyaluronic acid from eggshell membrane
US20040180025A1 (en) * 2003-03-12 2004-09-16 New Life Resources, Llc Therapeutic, nutraceutical and cosmetic applications for eggshell membrane and processed eggshell membrane preparations
US20080063677A1 (en) * 2004-03-10 2008-03-13 New Life Resources, Llc Therapeutic, nutraceutical and cosmetic applications for eggshell membrane and processed eggshell membrane preparations
US8580315B2 (en) * 2004-03-10 2013-11-12 Esm Technologies, Llc Anti-inflammatory activity of eggshell membrane and processed eggshell membrane preparations
US7002007B2 (en) * 2004-05-28 2006-02-21 Calcigen Corporation Production of high molecular weight hyaluronates
US8802651B2 (en) 2004-06-30 2014-08-12 Abbott Medical Optics Inc. Hyaluronic acid in the enhancement of lens regeneration
AU2005287478B2 (en) 2004-09-23 2011-05-19 Bayer Intellectual Property Gmbh Methods and means for producing hyaluronan
EP1640457A1 (de) * 2004-09-23 2006-03-29 Bayer CropScience GmbH Verfahren und Mittel zur Herstellung von Hyaluronan
EP1772052A1 (de) 2005-10-05 2007-04-11 Bayer CropScience GmbH Verbesserte Verfahren und Mittel zur Herstellung von Hyaluronan
US7682811B2 (en) * 2006-01-27 2010-03-23 University Of Massachusetts Systems and methods for producing biofuels and related materials
US7674781B2 (en) * 2006-04-28 2010-03-09 Heather Sheardown Hyaluronic acid-retaining polymers
KR101509139B1 (ko) * 2006-11-23 2015-04-08 주식회사 엘지생명과학 히알루론산의 정제방법
US9579341B2 (en) 2007-05-16 2017-02-28 Johnson & Johnson Consumer Inc. Preserved compositions containing hyaluronic acid or a pharmaceutically-acceptable salt thereof and related methods
US8609634B2 (en) 2007-05-16 2013-12-17 Mcneil-Ppc, Inc. Preserved compositions containing hyaluronic acid or a pharmaceutically-acceptable salt thereof and related methods
KR101322227B1 (ko) 2011-09-30 2013-10-28 일동제약주식회사 스트렙토코커스 디스갈락티애 id9103 균주 및 이를 이용한 히알루론산 생산 방법
JP2017112901A (ja) 2015-12-24 2017-06-29 キッコーマン株式会社 高分子ヒアルロン酸の製造方法
JP7444370B2 (ja) * 2017-08-04 2024-03-06 株式会社明治 乳酸菌の培養方法
US11129862B2 (en) 2017-08-30 2021-09-28 Johnson & Johnson Consumer Inc. Ophthalmic compositions

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4141973A (en) * 1975-10-17 1979-02-27 Biotrics, Inc. Ultrapure hyaluronic acid and the use thereof
US4517295A (en) * 1983-02-18 1985-05-14 Diagnostic, Inc. Hyaluronic acid from bacterial culture
NO161573C (no) * 1983-11-25 1989-08-30 Miles Inc Fremgangsmaate til fremstilling av hyaluronsyre.
US4784990A (en) * 1985-01-18 1988-11-15 Bio-Technology General Corporation High molecular weight sodium hyaluronate
CA1328841C (en) 1987-06-12 1994-04-26 Karen K. Brown Method for the microbiological production of non-antigenic hyaluronic acid
JPS6467196A (en) * 1987-09-08 1989-03-13 Yakult Honsha Kk Production of hyaluronic acid and strain used therefor
JPH07116243B2 (ja) * 1988-12-21 1995-12-13 理研ビタミン株式会社 ヒアルロン酸ビーズの製造法
SE8900422D0 (sv) * 1989-02-08 1989-02-08 Pharmacia Ab Tvaerbundna hyaluronatgeler samt foerfarande foer framstaellning av dessa
US5015577A (en) * 1989-08-29 1991-05-14 Board Of Regents, The University Of Texas System DNA encoding hyaluronate synthase
GB9024223D0 (en) * 1990-11-07 1990-12-19 Fermentech Ltd Production of hyaluronic acid
US5681825A (en) 1993-03-15 1997-10-28 Lindqvist; Bengt Surgical method
SE9401806D0 (sv) * 1994-05-26 1994-05-26 Pharmacia Ab Method and means for the production of hyaluronic acid

Also Published As

Publication number Publication date
DE69527626T2 (de) 2003-02-13
PT760863E (pt) 2002-11-29
AU699404B2 (en) 1998-12-03
EP0760863B1 (en) 2002-07-31
ATE221576T1 (de) 2002-08-15
DE69527626D1 (de) 2002-09-05
US6090596A (en) 2000-07-18
US20030134393A1 (en) 2003-07-17
CA2191197A1 (en) 1995-12-07
JPH10501128A (ja) 1998-02-03
NZ287583A (en) 1998-02-26
JP3720361B2 (ja) 2005-11-24
WO1995033067A1 (en) 1995-12-07
CA2191197C (en) 2002-01-15
US6537795B1 (en) 2003-03-25
ES2180639T3 (es) 2003-02-16
AU2633595A (en) 1995-12-21
EP0760863A1 (en) 1997-03-12
US7323329B2 (en) 2008-01-29
SE9401806D0 (sv) 1994-05-26

Similar Documents

Publication Publication Date Title
SE9401806D0 (sv) Method and means for the production of hyaluronic acid
ATE193550T1 (de) Rekonstruiertes knorpelgewebe
BR9303946A (pt) Macromolécula dendrítica e preparação da mesma
CA2101447A1 (en) 3-difluoromethylpyrazolecarboxamide fungicides
NO303970B1 (no) Uorgansik komposittmembran omfattende molekylvektkrystaller, og fremgangsmåte for fremstilling av membranen
EP2298927A3 (en) Methods for treating cancers and pathogen infections using antigen-presenting cells loaded with RNA
ATE442613T1 (de) Umkehrbare armbanduhr
BG101384A (en) New pesticide proteins and strains
DK0853636T3 (da) Podepolymeriseret latexpolymer med en gradientpolymermorfologi og fremgangsmåde til fremstilling deraf
DK0762892T3 (da) Difteritoksinvacciner, der bærer et muteret R-domæne
HUP9900919A2 (hu) 2,5-D-Mannóz-csoportot tartalmazó B antigén csoportba tartozó II és III típusú streptococcus poliszacharid-fragmentumok és ezeket tartalmazó vakcinakonjugátumok
DK0441695T3 (da) Fremgangsmåde til fremstilling af human faktor VIII og analoger af faktor VIII
DK0677116T3 (da) Fremgangsmåde til fremstilling af immunosuppressive midler og en ny mikroorganismeart til anvendelse deri
NZ307444A (en) Polyphenol oxidase genes from lettuce and banana
DE69132759D1 (de) In protein-freiem Medium wachsende Zellen, die die Replication von exogenen Genen steigern
NO985462D0 (no) Karbohydrat-derivater og fastfase-syntese derav
DE69433110D1 (de) Allogenes vakzin und synthesemethode für selbiges
GR1000639B (el) Μεθοδος για την παρασκευη μιας συνθεσεως για την αντιμετωπιση της αμυγδαλιτιδας.
CA2261987A1 (en) Vectors for inhibiting hiv and tumor growth
DK248690A (da) Fremgangsmaade, vektorer og bakteriestammer til kloning og forstaerkning af store dna-fragmenter samt bakteriophagindpakning af denne dna
DE69013425D1 (de) Pseudomonasmutant, yzh-Stamm und Verfahren zur Herstellung der 851yzh-Nährlösung mittels dieses Stammes.
AU4383093A (en) Heteroatomic oligonucleoside linkages
DK55289A (da) Praepolymer, polymer dannet dermed og fremgangsmaader til fremstilling deraf
MX9804068A (es) Nuevos derivados de quinoxalindiona, su preparacion y empleo en medicamentos.
GR3031236T3 (en) Process for the preparation of pilocarpine.