ES2180639T3 - Procedimiento y medios para la produccion de acido hialuronico. - Google Patents

Procedimiento y medios para la produccion de acido hialuronico.

Info

Publication number
ES2180639T3
ES2180639T3 ES95921198T ES95921198T ES2180639T3 ES 2180639 T3 ES2180639 T3 ES 2180639T3 ES 95921198 T ES95921198 T ES 95921198T ES 95921198 T ES95921198 T ES 95921198T ES 2180639 T3 ES2180639 T3 ES 2180639T3
Authority
ES
Spain
Prior art keywords
sup
density
supercapsulated
molecular weight
hyaluronic acid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES95921198T
Other languages
English (en)
Inventor
Sten Stahl
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pfizer Health AB
Original Assignee
Pharmacia AB
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pharmacia AB filed Critical Pharmacia AB
Application granted granted Critical
Publication of ES2180639T3 publication Critical patent/ES2180639T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • C12N1/205—Bacterial isolates
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/26—Preparation of nitrogen-containing carbohydrates
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00—Microorganisms ; Processes using microorganisms
    • C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
    • C12R2001/46—Streptococcus ; Enterococcus; Lactococcus
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/8215—Microorganisms
    • Y10S435/822—Microorganisms using bacteria or actinomycetales
    • Y10S435/885—Streptococcus

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Biomedical Technology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)

Abstract

CEPAS DE ESTREPTOCOCOS DEL GRUPO A O C SUPERENCAPSULADAS, Y UTILIZACION DE LAS MISMAS PARA LA PRODUCCION DE ACIDO HIALURONICO DE PESO MOLECULAR MAYOR DE 6 MILLONES.
ES95921198T 1994-05-26 1995-05-24 Procedimiento y medios para la produccion de acido hialuronico. Expired - Lifetime ES2180639T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE9401806A SE9401806D0 (sv) 1994-05-26 1994-05-26 Method and means for the production of hyaluronic acid

Publications (1)

Publication Number Publication Date
ES2180639T3 true ES2180639T3 (es) 2003-02-16

Family

ID=20394129

Family Applications (1)

Application Number Title Priority Date Filing Date
ES95921198T Expired - Lifetime ES2180639T3 (es) 1994-05-26 1995-05-24 Procedimiento y medios para la produccion de acido hialuronico.

Country Status (13)

Country Link
US (3) US6090596A (es)
EP (1) EP0760863B1 (es)
JP (1) JP3720361B2 (es)
AT (1) ATE221576T1 (es)
AU (1) AU699404B2 (es)
CA (1) CA2191197C (es)
DE (1) DE69527626T2 (es)
DK (1) DK0760863T3 (es)
ES (1) ES2180639T3 (es)
NZ (1) NZ287583A (es)
PT (1) PT760863E (es)
SE (1) SE9401806D0 (es)
WO (1) WO1995033067A1 (es)

Families Citing this family (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE9401806D0 (sv) * 1994-05-26 1994-05-26 Pharmacia Ab Method and means for the production of hyaluronic acid
US6455304B1 (en) 1994-07-01 2002-09-24 The Board Of Regents Of The University Of Oklahoma Hyaluronate synthase gene and uses thereof
US6951743B2 (en) 1997-10-31 2005-10-04 University Of Oklahoma Board Of Regents Hyaluronan synthase genes and expression thereof in bacillus hosts
US7091008B1 (en) 1994-07-01 2006-08-15 The Board Of Regents Of The University Of Oklahoma Hyaluronan synthase genes and expression thereof in Bacillus hosts
EP1025211B1 (en) 1997-10-31 2004-12-15 The Board of Regents of The University of Oklahoma Hyaluronan synthase gene and uses thereof
CN101113436B (zh) 1997-10-31 2013-02-06 俄克拉何马大学董事会 透明质酸合酶基因及其应用
US7223571B2 (en) 1998-04-02 2007-05-29 The Board Of Regents Of The Universtiy Of Oklahoma Targeted glycosaminoglycan polymers by polymer grafting and methods of making and using same
US20060188966A1 (en) 1998-04-02 2006-08-24 Deangelis Paul L Natural, chimeric and hybrid glycosaminoglycan polymers and methods of making and using same
US6987023B2 (en) 1998-04-02 2006-01-17 The Board Of Regents Of The University Of Oklahoma DNA encoding hyaluronan synthase from Pasteurella multocida and methods of use
US7094581B2 (en) 1998-10-26 2006-08-22 The Board Of Regents Of The University Of Oklahoma Hyaluronan synthases and methods of making and using same
US6610666B1 (en) * 1999-11-08 2003-08-26 Bio-Hyos Ab Hyaluronan product and process for manufacturing thereof
RU2005102604A (ru) * 2002-07-03 2005-09-10 Перикор Сайенс, Инк. (Us) Композиция гиалуроновой кислоты и способы применения
KR100472007B1 (ko) * 2002-08-19 2005-03-10 주식회사 코오롱 히아루론산 생산 균주 및 상기 균주를 이용한 히아루론산 생산방법
US7575914B2 (en) 2002-08-19 2009-08-18 Kolon Life Science, Inc. Microorganism producing hyaluronic acid and purification method of hyaluronic acid
US20080063677A1 (en) * 2004-03-10 2008-03-13 New Life Resources, Llc Therapeutic, nutraceutical and cosmetic applications for eggshell membrane and processed eggshell membrane preparations
US6946551B2 (en) 2003-03-12 2005-09-20 New Life Resources, Llc Preparation of hyaluronic acid from eggshell membrane
US20040180025A1 (en) * 2003-03-12 2004-09-16 New Life Resources, Llc Therapeutic, nutraceutical and cosmetic applications for eggshell membrane and processed eggshell membrane preparations
US8580315B2 (en) * 2004-03-10 2013-11-12 Esm Technologies, Llc Anti-inflammatory activity of eggshell membrane and processed eggshell membrane preparations
US7002007B2 (en) * 2004-05-28 2006-02-21 Calcigen Corporation Production of high molecular weight hyaluronates
US8802651B2 (en) * 2004-06-30 2014-08-12 Abbott Medical Optics Inc. Hyaluronic acid in the enhancement of lens regeneration
ES2327944T3 (es) 2004-09-23 2009-11-05 Bayer Cropscience Ag Metodos y medios para producir hialuronano.
EP1640457A1 (de) * 2004-09-23 2006-03-29 Bayer CropScience GmbH Verfahren und Mittel zur Herstellung von Hyaluronan
EP1772052A1 (de) 2005-10-05 2007-04-11 Bayer CropScience GmbH Verbesserte Verfahren und Mittel zur Herstellung von Hyaluronan
EP1984514A4 (en) * 2006-01-27 2010-09-01 Univ Massachusetts SYSTEMS AND METHOD FOR PRODUCING BIOFUELS AND CORRESPONDING MATERIALS
US7674781B2 (en) * 2006-04-28 2010-03-09 Heather Sheardown Hyaluronic acid-retaining polymers
KR101509139B1 (ko) * 2006-11-23 2015-04-08 주식회사 엘지생명과학 히알루론산의 정제방법
US9579341B2 (en) 2007-05-16 2017-02-28 Johnson & Johnson Consumer Inc. Preserved compositions containing hyaluronic acid or a pharmaceutically-acceptable salt thereof and related methods
US8609634B2 (en) 2007-05-16 2013-12-17 Mcneil-Ppc, Inc. Preserved compositions containing hyaluronic acid or a pharmaceutically-acceptable salt thereof and related methods
KR101322227B1 (ko) 2011-09-30 2013-10-28 일동제약주식회사 스트렙토코커스 디스갈락티애 ｉｄ9103 균주 및 이를 이용한 히알루론산 생산 방법
JP2017112901A (ja) 2015-12-24 2017-06-29 キッコーマン株式会社 高分子ヒアルロン酸の製造方法
JP7444370B2 (ja) * 2017-08-04 2024-03-06 株式会社明治 乳酸菌の培養方法
US11129862B2 (en) 2017-08-30 2021-09-28 Johnson & Johnson Consumer Inc. Ophthalmic compositions

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4141973A (en) * 1975-10-17 1979-02-27 Biotrics, Inc. Ultrapure hyaluronic acid and the use thereof
US4517295A (en) * 1983-02-18 1985-05-14 Diagnostic, Inc. Hyaluronic acid from bacterial culture
NO161573C (no) * 1983-11-25 1989-08-30 Miles Inc Fremgangsmaate til fremstilling av hyaluronsyre.
US4784990A (en) * 1985-01-18 1988-11-15 Bio-Technology General Corporation High molecular weight sodium hyaluronate
CA1328841C (en) 1987-06-12 1994-04-26 Karen K. Brown Method for the microbiological production of non-antigenic hyaluronic acid
JPS6467196A (en) * 1987-09-08 1989-03-13 Yakult Honsha Kk Production of hyaluronic acid and strain used therefor
JPH07116243B2 (ja) * 1988-12-21 1995-12-13 理研ビタミン株式会社 ヒアルロン酸ビーズの製造法
SE8900422D0 (sv) * 1989-02-08 1989-02-08 Pharmacia Ab Tvaerbundna hyaluronatgeler samt foerfarande foer framstaellning av dessa
US5015577A (en) * 1989-08-29 1991-05-14 Board Of Regents, The University Of Texas System DNA encoding hyaluronate synthase
GB9024223D0 (en) * 1990-11-07 1990-12-19 Fermentech Ltd Production of hyaluronic acid
US5681825A (en) 1993-03-15 1997-10-28 Lindqvist; Bengt Surgical method
SE9401806D0 (sv) * 1994-05-26 1994-05-26 Pharmacia Ab Method and means for the production of hyaluronic acid

Also Published As

Publication number Publication date
US6090596A (en) 2000-07-18
JP3720361B2 (ja) 2005-11-24
AU699404B2 (en) 1998-12-03
EP0760863A1 (en) 1997-03-12
WO1995033067A1 (en) 1995-12-07
DE69527626T2 (de) 2003-02-13
JPH10501128A (ja) 1998-02-03
NZ287583A (en) 1998-02-26
DE69527626D1 (de) 2002-09-05
ATE221576T1 (de) 2002-08-15
CA2191197A1 (en) 1995-12-07
DK0760863T3 (da) 2002-11-25
CA2191197C (en) 2002-01-15
US7323329B2 (en) 2008-01-29
SE9401806D0 (sv) 1994-05-26
PT760863E (pt) 2002-11-29
AU2633595A (en) 1995-12-21
EP0760863B1 (en) 2002-07-31
US6537795B1 (en) 2003-03-25
US20030134393A1 (en) 2003-07-17

Similar Documents

Publication Publication Date Title
SE9401806D0 (sv) Method and means for the production of hyaluronic acid
EP2298927A3 (en) Methods for treating cancers and pathogen infections using antigen-presenting cells loaded with RNA
WO1993020400A3 (en) Ballistic-resistant article and process for making the same
ATE193550T1 (de) Rekonstruiertes knorpelgewebe
ITRM960904A0 (it) Procedimento per la produzione di lamierino magnetico a grano orienta= to, con elevate caratteristiche magnetiche
FI970809A0 (fi) Menetelmä kuituvahvistettujen kserogeelien valmistamiseksi sekä niiden käyttö
HUP9802538A2 (hu) Vektorok és eljárások helyspecifikus rekombináció előidézésére
HUP9900919A2 (hu) 2,5-D-Mannóz-csoportot tartalmazó B antigén csoportba tartozó II és III típusú streptococcus poliszacharid-fragmentumok és ezeket tartalmazó vakcinakonjugátumok
ZA867670B (en) Method for alleviation of panic disorders
ES2075378T3 (es) Procedimiento para la preparacion del factor viii humano y de analogos del factor viii.
ES2061823T3 (es) Nueva proteina h que es capaz de fijarse a igg, gen que codifica dicha proteina h, y un procedimiento para producir dicha proteina h.
ES539187A0 (es) Un procedimiento de preparacion de una forma gelenica porosa a base de policaprolactona.
AU7237391A (en) Carrier-bound recombinant protein, process for producing it and its use as an immunogen and vaccine
IT1126577B (it) 4(3h)-chinazolinoni sostituiti nella meta' 3-aromatica,procedimento per la loro produzione e loro impiego
DE69132759D1 (de) In protein-freiem Medium wachsende Zellen, die die Replication von exogenen Genen steigern
ES2160711T3 (es) Procedimiento para la fabricacion de elementos estructurales de acero de alta resistencia.
ES2119006T3 (es) Cepa mutante de streptococcus zooepidemicus para preparar acido hialuronico.
EP1946767A3 (en) Autologous T-cell vaccines against multiple sclerosis
FI943671A7 (fi) Prosessi stabiloitujen, osittain dehydratoitujen aromaattisten kasviva lmisteiden tuottamiseksi ja tuotetut valmisteet
GR1001125B (el) Μεθοδος δια την εις βιομηχανικη κλιμακα παραγωγην της βμυ 21502.
GR1000639B (el) Μεθοδος για την παρασκευη μιας συνθεσεως για την αντιμετωπιση της αμυγδαλιτιδας.
AU1446192A (en) Process for the production of antibiotics, dna-sequences, recombinant-dna-constructs and microbial strains used therein
DE3372372D1 (en) High molecular weight aromatic polyesters, process for their production and their use in the production of moulded articles
DE69013425D1 (de) Pseudomonasmutant, yzh-Stamm und Verfahren zur Herstellung der 851yzh-Nährlösung mittels dieses Stammes.
JPS6467196A (en) Production of hyaluronic acid and strain used therefor