DK0760944T3 - Fremgangsmåde til påvisning af udklingende exciteret luminescens - Google Patents

Fremgangsmåde til påvisning af udklingende exciteret luminescens

Info

Publication number
DK0760944T3
DK0760944T3 DK95922453T DK95922453T DK0760944T3 DK 0760944 T3 DK0760944 T3 DK 0760944T3 DK 95922453 T DK95922453 T DK 95922453T DK 95922453 T DK95922453 T DK 95922453T DK 0760944 T3 DK0760944 T3 DK 0760944T3
Authority
DK
Denmark
Prior art keywords
pct
luminescence
layer
sec
substances
Prior art date
Application number
DK95922453T
Other languages
English (en)
Inventor
Dieter Neuschaefer
Gert L Duveneck
Markus Ehrat
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis Ag filed Critical Novartis Ag
Application granted granted Critical
Publication of DK0760944T3 publication Critical patent/DK0760944T3/da

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/75Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated
    • G01N21/77Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64Fluorescence; Phosphorescence
    • G01N21/645Specially adapted constructive features of fluorimeters
    • G01N21/648Specially adapted constructive features of fluorimeters using evanescent coupling or surface plasmon coupling for the excitation of fluorescence
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/75Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated
    • G01N21/77Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator
    • G01N21/7703Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator using reagent-clad optical fibres or optical waveguides
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/75Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated
    • G01N21/77Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator
    • G01N21/7703Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator using reagent-clad optical fibres or optical waveguides
    • G01N21/774Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator using reagent-clad optical fibres or optical waveguides the reagent being on a grating or periodic structure
    • G01N21/7743Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator using reagent-clad optical fibres or optical waveguides the reagent being on a grating or periodic structure the reagent-coated grating coupling light in or out of the waveguide

Landscapes

  • Chemical & Material Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Plasma & Fusion (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Testing, Inspecting, Measuring Of Stereoscopic Televisions And Televisions (AREA)
  • Manufacture, Treatment Of Glass Fibers (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)
DK95922453T 1994-05-27 1995-05-17 Fremgangsmåde til påvisning af udklingende exciteret luminescens DK0760944T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CH164394 1994-05-27
PCT/EP1995/001845 WO1995033197A1 (en) 1994-05-27 1995-05-17 Process for detecting evanescently excited luminescence

Publications (1)

Publication Number Publication Date
DK0760944T3 true DK0760944T3 (da) 2002-08-05

Family

ID=4215258

Family Applications (1)

Application Number Title Priority Date Filing Date
DK95922453T DK0760944T3 (da) 1994-05-27 1995-05-17 Fremgangsmåde til påvisning af udklingende exciteret luminescens

Country Status (21)

Country Link
US (2) US5822472A (da)
EP (2) EP0760944B1 (da)
JP (3) JP3645907B2 (da)
KR (1) KR970703527A (da)
CN (2) CN1149336A (da)
AT (2) ATE172300T1 (da)
AU (2) AU689604B2 (da)
CA (2) CA2190362A1 (da)
CZ (2) CZ347196A3 (da)
DE (2) DE69526438T2 (da)
DK (1) DK0760944T3 (da)
ES (1) ES2174948T3 (da)
FI (2) FI964664A7 (da)
HU (2) HUT76406A (da)
IL (2) IL113849A0 (da)
MX (1) MXPA96005828A (da)
PL (2) PL317379A1 (da)
SK (2) SK151396A3 (da)
TW (2) TW295624B (da)
WO (2) WO1995033198A1 (da)
ZA (2) ZA954327B (da)

Families Citing this family (159)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE69526438T2 (de) * 1994-05-27 2002-10-31 Novartis Ag, Basel Verfahren zum nachweis abklingend angeregter lumineszenz
US5814565A (en) * 1995-02-23 1998-09-29 University Of Utah Research Foundation Integrated optic waveguide immunosensor
TW302435B (da) * 1995-05-12 1997-04-11 Ciba Geigy Ag
GB9602542D0 (en) * 1996-02-08 1996-04-10 Fisons Plc Analytical device
US6211954B1 (en) 1996-03-30 2001-04-03 Novartis Ag Integrated optical luminescence sensor
JPH102860A (ja) * 1996-06-17 1998-01-06 Olympus Optical Co Ltd 微小物質検鏡装置
US6395558B1 (en) 1996-08-29 2002-05-28 Zeptosens Ag Optical chemical/biochemical sensor
EP0843173A1 (de) 1996-11-18 1998-05-20 Novartis AG Flusszelle sowie Vorrichtung zur Erzeugung evaneszent angeregter Strahlung
DE59712460D1 (de) 1996-11-18 2005-12-01 Novartis Ag Messvorrichtung mit einem planaren optischen wellenleiter
EP1012580B1 (de) * 1997-09-10 2004-06-23 Artificial Sensing Instruments ASI AG Optischer sensor und optisches verfahren zur charakterisierung einer chemischen und/oder biochemischen substanz
JP4662623B2 (ja) * 1998-02-05 2011-03-30 ノバルティス アーゲー ルミネッセンスを測定する方法及び装置
EP2112501A1 (de) 1998-02-05 2009-10-28 Novartis Ag Verfahren und Vorrichtung zur Lumineszenzmessung
US6758337B2 (en) * 1999-03-02 2004-07-06 Meadwestvaco Packaging Systems, Llc Beverage carton with strap type carrying handle
EP0957354A3 (en) * 1998-03-20 2000-03-22 IA Inc. Method and apparatus for measuring binding between biological molecules
DE19815109A1 (de) * 1998-04-03 1999-10-07 Bodenseewerk Perkin Elmer Co Vorrichtung zum Nachweis eines Fluoreszenzfarbstoffs
FR2778986B1 (fr) * 1998-05-22 2000-07-21 Suisse Electronique Microtech Capteur optique utilisant une reaction immunologique et un marqueur fluorescent
WO2000005582A2 (en) * 1998-07-21 2000-02-03 Burstein Laboratories, Inc. Optical disc-based assay devices and methods
US6320991B1 (en) 1998-10-16 2001-11-20 Imation Corp. Optical sensor having dielectric film stack
US6245518B1 (en) * 1998-12-11 2001-06-12 Hyseq, Inc. Polynucleotide arrays and methods of making and using the same
DE69933193T2 (de) * 1999-02-25 2007-08-02 C.S.E.M. Centre Suisse D'electronique Et De Microtechnique S.A. Integrierter optischer Sensor und Verfahren zum integrierten optischen Nachweis einer Substanz
US6192168B1 (en) * 1999-04-09 2001-02-20 The United States Of America As Represented By The Secretary Of The Navy Reflectively coated optical waveguide and fluidics cell integration
US6137117A (en) * 1999-06-21 2000-10-24 The United States Of America As Represented By The Secretary Of The Navy Integrating multi-waveguide sensor
AU5760500A (en) * 1999-06-23 2001-01-09 Patrick Toomey Water detection and source identification methods for structures using electromagnetic radiation spectroscopy
ES2273704T3 (es) 1999-07-05 2007-05-16 Novartis Ag Procedimiento para utilizar un plataforma de deteccion.
US6771376B2 (en) 1999-07-05 2004-08-03 Novartis Ag Sensor platform, apparatus incorporating the platform, and process using the platform
EP1274986B1 (de) 1999-08-13 2011-07-13 Bayer Technology Services GmbH Vorrichtung und verfahren zur multianalytbestimmung
US6667179B1 (en) * 1999-10-28 2003-12-23 The Board Of Trustees Of The University Of Illinois Semiconductor luminescence quenchers for detecting proximal molecular binding events
US7167615B1 (en) 1999-11-05 2007-01-23 Board Of Regents, The University Of Texas System Resonant waveguide-grating filters and sensors and methods for making and using same
FR2801977B1 (fr) * 1999-12-02 2002-05-17 Commissariat Energie Atomique Amplification d'un signal de fluorescence emis par un echantillon surfacique
ATE267047T1 (de) 1999-12-17 2004-06-15 Zeptosens Ag Anordnung von probenbehältnissen und deren verwendung zur multianalytbestimmung
US6510263B1 (en) * 2000-01-27 2003-01-21 Unaxis Balzers Aktiengesellschaft Waveguide plate and process for its production and microtitre plate
WO2001079821A1 (de) * 2000-04-14 2001-10-25 Zeptosens Ag Gitter-wellenleiter-struktur zur verstärkung eines anregungsfeldes und deren verwendung
JP2003532123A (ja) 2000-04-28 2003-10-28 エッジライト バイオサイエンシズ インコーポレイテッド マイクロアレーエバネッセント波蛍光検出装置
WO2001092870A2 (de) 2000-06-02 2001-12-06 Zeptosens Ag Kit und verfahren zur multianalytbestimmung
EP1311824A4 (en) * 2000-06-25 2010-12-08 Affymetrix Inc OPTICALLY ACTIVE SUBSTRATES
DE50115382D1 (de) 2000-08-09 2010-04-22 Artificial Sensing Instr Asi A Wellenleitergitterstruktur und optische messanordnung
AU2001289853A1 (en) * 2000-09-04 2002-03-22 Zeptosens Ag Multianalyte determination system and methods
WO2002020873A2 (de) * 2000-09-05 2002-03-14 Zeptosens Ag Verfahren zur abscheidung von mono- und mehrfachschichten von organophosphor- und -phosphonsäuren und deren salzen sowie deren verwendung
EP1356291B1 (de) * 2000-12-06 2011-05-04 Ecole Polytechnique Fédérale de Lausanne (EPFL) Verfahren zur herstellung eines bioanalytischen reagenzes, nachweisverfahren beruhend auf der verwendung des bioanalytischen reagenz, sowie dessen verwendung
FR2818382B1 (fr) * 2000-12-20 2003-02-21 Commissariat Energie Atomique Support pour determiner un analyte tel qu'une cible adn ou arn, comportant un filtre spectral selectif
DE10108483A1 (de) * 2001-02-22 2002-09-05 Bayer Ag Phosphorhaltige Polymere für optischen Signalwandler
ES2392395T3 (es) 2001-03-01 2012-12-10 Sicpa Holding Sa Detector mejorado de características de luminiscencia
EP1373875A2 (de) * 2001-04-02 2004-01-02 Zeptosens AG Optische struktur zur multi-photonen-anregung und deren verwendung
DE10133844B4 (de) * 2001-07-18 2006-08-17 Micronas Gmbh Verfahren und Vorrichtung zur Detektion von Analyten
US6782013B2 (en) * 2001-07-25 2004-08-24 Jds Uniphase Corporation Waveguide wavelength locker
US6671304B2 (en) * 2001-08-28 2003-12-30 The United States Of America As Represented By The Secretary Of The Navy Amplitude-modulated laser for high-bandwidth communications systems
ATE528117T1 (de) 2001-08-30 2011-10-15 Bayer Technology Services Gmbh Verfahren zur herstellung von abformkörpern, insbesondere optischen strukturen, und deren verwendung
US20030124599A1 (en) * 2001-11-14 2003-07-03 Shiping Chen Biochemical analysis system with combinatorial chemistry applications
DE10158149A1 (de) * 2001-11-28 2003-06-18 Bayer Ag Silangruppen enthaltende Polymere
US7179654B2 (en) * 2002-03-18 2007-02-20 Agilent Technologies, Inc. Biochemical assay with programmable array detection
JP2003308714A (ja) * 2002-04-17 2003-10-31 Fuji Photo Film Co Ltd 導光フィルム
US20030232427A1 (en) * 2002-06-18 2003-12-18 Montagu Jean I. Optically active substrates for examination of biological materials
US7154598B2 (en) * 2002-07-12 2006-12-26 Decision Biomarkers, Inc. Excitation and imaging of fluorescent arrays
US7384742B2 (en) * 2002-08-16 2008-06-10 Decision Biomarkers, Inc. Substrates for isolating reacting and microscopically analyzing materials
US7872804B2 (en) 2002-08-20 2011-01-18 Illumina, Inc. Encoded particle having a grating with variations in the refractive index
US7508608B2 (en) 2004-11-17 2009-03-24 Illumina, Inc. Lithographically fabricated holographic optical identification element
US7619819B2 (en) 2002-08-20 2009-11-17 Illumina, Inc. Method and apparatus for drug product tracking using encoded optical identification elements
US7164533B2 (en) 2003-01-22 2007-01-16 Cyvera Corporation Hybrid random bead/chip based microarray
US7900836B2 (en) 2002-08-20 2011-03-08 Illumina, Inc. Optical reader system for substrates having an optically readable code
US7441703B2 (en) 2002-08-20 2008-10-28 Illumina, Inc. Optical reader for diffraction grating-based encoded optical identification elements
EP1535241A1 (en) 2002-08-20 2005-06-01 Cyvera Corporation Diffraction grating-based optical identification element
US20060105337A1 (en) * 2002-08-30 2006-05-18 Brian Warner Solid phase based nucleic acid assays combining high affinity and high specificity
AU2003258683A1 (en) * 2002-09-03 2004-03-29 Zeptosens Ag Analytical platform and detection method with analytes which are to be detected in a sample in the form of immobilized specific binding partners
JP2005537487A (ja) 2002-09-03 2005-12-08 ツェプトゼンス アクチエンゲゼルシャフト 試料中において任意には分画された後の試料中において、固定化特異的結合パートナーとして測定される分析対象物を用いる分析プラットフォーム及び検出法
AU2003274979A1 (en) 2002-09-12 2004-04-30 Cyvera Corporation Chemical synthesis using diffraction grating-based encoded optical elements
EP1540591A1 (en) 2002-09-12 2005-06-15 Cyvera Corporation Diffraction grating-based encoded micro-particles for multiplexed experiments
US7092160B2 (en) 2002-09-12 2006-08-15 Illumina, Inc. Method of manufacturing of diffraction grating-based optical identification element
US20100255603A9 (en) 2002-09-12 2010-10-07 Putnam Martin A Method and apparatus for aligning microbeads in order to interrogate the same
AU2003267192A1 (en) 2002-09-12 2004-04-30 Cyvera Corporation Method and apparatus for aligning elongated microbeads in order to interrogate the same
CA2499037A1 (en) 2002-09-12 2004-03-25 Cyvera Corporation Method and apparatus for labelling using diffraction grating-based encoded optical identification elements
DE10245435B4 (de) * 2002-09-27 2006-03-16 Micronas Gmbh Vorrichtung zur Detektion mindestens eines in einer zu untersuchenden Probe enthaltenen Liganden
US7027163B2 (en) * 2003-01-24 2006-04-11 General Dynamics Advanced Information Systems, Inc. Grating sensor
US7445938B2 (en) * 2003-01-24 2008-11-04 General Dynamics Advanced Information Systems, Inc. System and method for detecting presence of analytes using gratings
US7545494B2 (en) 2003-07-23 2009-06-09 Bayer Technology Services Gmbh Analytical system and method for analyzing nonlinear optical signals
DE10353694A1 (de) * 2003-11-18 2005-06-30 Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. Mikroskopievorrichtung
GB0327755D0 (en) * 2003-12-01 2003-12-31 Elliott Stephen R Optical-sensor chip
JP4480130B2 (ja) * 2003-12-16 2010-06-16 キヤノン株式会社 光学分析装置
US7433123B2 (en) 2004-02-19 2008-10-07 Illumina, Inc. Optical identification element having non-waveguide photosensitive substrate with diffraction grating therein
CA2559803A1 (en) * 2004-03-03 2005-10-13 Bayer Technology Services Gmbh Analytical platform and method for generating protein expression profiles of cell populations
US7080839B2 (en) * 2004-06-29 2006-07-25 Michael Shackleford Blackjack variations
JP5296377B2 (ja) 2004-07-02 2013-09-25 バイエル・ヘルスケア・エルエルシー 流体試料中の検体の判定を行うために使用される光導体検査センサ、およびその製作方法
ES2292273B1 (es) * 2004-07-13 2009-02-16 Fabrica Nacional De Moneda Y Timbre - Real Casa De La Moneda Pigmentos luminiscentes utilizados en documentos de seguridad y procedimiento de deteccion de los mismos.
US7678567B2 (en) * 2004-07-26 2010-03-16 Kabushiki Kaisha Toshiba Optical biosensor
EP1621869B1 (en) * 2004-07-26 2015-08-19 Kabushiki Kaisha Toshiba Optical biosensor
CN101696937B (zh) * 2004-07-30 2012-07-04 株式会社东芝 光学式生物传感器
CN100449313C (zh) * 2004-07-30 2009-01-07 株式会社东芝 光学式生物传感器
WO2006055735A2 (en) 2004-11-16 2006-05-26 Illumina, Inc Scanner having spatial light modulator
EP1869615B1 (en) 2004-11-16 2010-03-03 Illumina, Inc. Methods and apparatus for reading coded microbeads
US7403284B2 (en) * 2004-12-16 2008-07-22 Andevices, Inc. Integrated optics based high-resolution spectrophotometer
JP2005099054A (ja) * 2004-12-27 2005-04-14 Olympus Corp 微小物質の蛍光測定装置
US7327908B1 (en) * 2005-03-07 2008-02-05 Lightsmyth Technologies Inc. Integrated optical sensor incorporating sets of diffractive elements
GB0507835D0 (en) * 2005-04-18 2005-05-25 Solexa Ltd Method and device for nucleic acid sequencing using a planar wave guide
ES2525324T3 (es) 2005-04-26 2014-12-22 Bayer Intellectual Property Gmbh Nuevo aparato y procedimiento de recubrimiento de sustratos portadores para la detección de analitos mediante un procedimiento de detección por afinidad
US7136005B1 (en) * 2005-05-05 2006-11-14 Analog Devices, Inc. Accurate low noise analog to digital converter system
JP5383190B2 (ja) * 2005-08-08 2014-01-08 コーニング インコーポレイテッド Ccd検出器の読み出し速度を増加させる方法
WO2007043005A1 (en) 2005-10-12 2007-04-19 Koninklijke Philips Electronics N. V. All polymer optical waveguide sensor
EP1941276A1 (de) 2005-10-29 2008-07-09 Bayer Technology Services GmbH Verfahren zur bestimmung eines oder mehrerer analyten in komplex zusammengesetzten proben biologischen ursprungs und dessen verwendung
US7623624B2 (en) 2005-11-22 2009-11-24 Illumina, Inc. Method and apparatus for labeling using optical identification elements characterized by X-ray diffraction
DE102005062785A1 (de) * 2005-12-28 2007-07-05 Robert Bosch Gmbh Regensensor, insbesondere für ein Kraftfahrzeug, und Verfahren zur Herstellung des Regensensors
US20070196863A1 (en) * 2006-02-17 2007-08-23 Hanson Technologies, Inc. Prion protein detection
US7951583B2 (en) 2006-03-10 2011-05-31 Plc Diagnostics, Inc. Optical scanning system
US8288157B2 (en) 2007-09-12 2012-10-16 Plc Diagnostics, Inc. Waveguide-based optical scanning systems
US8675199B2 (en) 2006-03-10 2014-03-18 Plc Diagnostics, Inc. Waveguide-based detection system with scanning light source
US9423397B2 (en) 2006-03-10 2016-08-23 Indx Lifecare, Inc. Waveguide-based detection system with scanning light source
US9976192B2 (en) 2006-03-10 2018-05-22 Ldip, Llc Waveguide-based detection system with scanning light source
US9528939B2 (en) 2006-03-10 2016-12-27 Indx Lifecare, Inc. Waveguide-based optical scanning systems
SE529711C2 (sv) * 2006-03-22 2007-11-06 Aamic Ab Fluorescensläsare
US7830575B2 (en) 2006-04-10 2010-11-09 Illumina, Inc. Optical scanner with improved scan time
WO2007127564A2 (en) 2006-04-26 2007-11-08 Siemens Medical Solutions Diagnostics Gmbh Solid phase based nucleic acid assays combining high affinity capturing and detection by specific hybridization
US20080101744A1 (en) * 2006-10-31 2008-05-01 Honeywell International Inc. Optical Waveguide Sensor Devices and Methods For Making and Using Them
US20100093107A1 (en) * 2006-12-14 2010-04-15 University Of Massachusetts Polymer-protein substrates for immunosorbent fluorescence assays
US9475051B2 (en) 2007-02-27 2016-10-25 Sony Corporation Nucleic acid amplifier
JP4458133B2 (ja) * 2007-02-27 2010-04-28 ソニー株式会社 核酸増幅装置
US20090325211A1 (en) * 2007-10-06 2009-12-31 Ye Fang System and method for dual-detection of a cellular response
AT506177B1 (de) * 2008-03-26 2009-07-15 Univ Graz Tech Optischer sensor
EP2110694B1 (en) 2008-04-18 2013-08-14 Sony DADC Austria AG Method for manufacturing an optical waveguide, optical waveguide, and sensor arrangement
DE102008019928A1 (de) 2008-04-21 2009-12-31 Siemens Healthcare Diagnostics Gmbh Polyelektrolyt-Monoschichten mit kovalenten Bindungsstellen für optische Signalwandler
GB2461026B (en) 2008-06-16 2011-03-09 Plc Diagnostics Inc System and method for nucleic acids sequencing by phased synthesis
US9212995B2 (en) 2009-03-02 2015-12-15 Mbio Diagnostics, Inc. System and method for detecting multiple molecules in one assay
US8300993B2 (en) * 2009-03-02 2012-10-30 Mbio Diagnostics, Inc. Waveguide with integrated lens
US8331751B2 (en) * 2009-03-02 2012-12-11 mBio Diagnositcs, Inc. Planar optical waveguide with core of low-index-of-refraction interrogation medium
US9658222B2 (en) 2009-03-02 2017-05-23 Mbio Diagnostics, Inc. Planar waveguide based cartridges and associated methods for detecting target analyte
AU2010234063A1 (en) 2009-04-09 2011-11-03 Bayer Intellectual Property Gmbh Device and method for the verification and quantitative analysis of analytes, particularly mycotoxins
DE102009016712A1 (de) 2009-04-09 2010-10-14 Bayer Technology Services Gmbh Einweg-Mikrofluidik-Testkassette zur Bioassay von Analyten
US8154716B2 (en) * 2009-09-04 2012-04-10 Octrolix Bv Waveguide-based sensor
DE102010019095B4 (de) * 2010-04-30 2016-12-08 Deutsches Zentrum für Luft- und Raumfahrt e.V. Verfahren und Vorrichtung zur Fluoreszenzlebensdauermessung
TW201217783A (en) 2010-09-15 2012-05-01 Mbio Diagnostics Inc System and method for detecting multiple molecules in one assay
CN103597335B (zh) * 2011-07-13 2015-12-09 英派尔科技开发有限公司 利用具有可刷新表面的表面等离子体监测分析物的方法和系统
US9989525B2 (en) * 2013-03-15 2018-06-05 Axela Inc. Diffraction based biosensor containing two diffractive gratings
US20150077756A1 (en) * 2013-06-13 2015-03-19 Lumense, Inc. System and method for continuous real-time monitoring of water at contaminated sites
JP6573899B2 (ja) 2013-11-17 2019-09-11 クアンタム−エスアイ インコーポレイテッドQuantum−Si Incorporated 分子をプローブし、検出し、及び分析するための、外部光源を備えた集積デバイス
US10018566B2 (en) 2014-02-28 2018-07-10 Ldip, Llc Partially encapsulated waveguide based sensing chips, systems and methods of use
US9702813B2 (en) * 2014-07-23 2017-07-11 Infineon Technologies Ag Sensing systems and methods using a coupling structure
CN112903639B (zh) 2014-08-08 2022-09-13 宽腾矽公司 用于对分子进行探测、检测和分析的带外部光源的集成装置
US10174363B2 (en) 2015-05-20 2019-01-08 Quantum-Si Incorporated Methods for nucleic acid sequencing
WO2016023010A1 (en) 2014-08-08 2016-02-11 Quantum-Si Incorporated Optical system and assay chip for probing, detecting, and analyzing molecules
EP3194935B1 (en) 2014-08-08 2018-10-31 Quantum-si Incorporated Integrated device for temporal binning of received photons
WO2016138427A1 (en) 2015-02-27 2016-09-01 Indx Lifecare, Inc. Waveguide-based detection system with scanning light source
US10605730B2 (en) 2015-05-20 2020-03-31 Quantum-Si Incorporated Optical sources for fluorescent lifetime analysis
US10246742B2 (en) 2015-05-20 2019-04-02 Quantum-Si Incorporated Pulsed laser and bioanalytic system
US11466316B2 (en) 2015-05-20 2022-10-11 Quantum-Si Incorporated Pulsed laser and bioanalytic system
TW202139919A (zh) 2016-02-17 2021-11-01 美商太斯萊特健康股份有限公司 用於生命期成像及偵測應用之感測器及裝置
CA3047133A1 (en) 2016-12-16 2018-06-21 Quantum-Si Incorporated Compact mode-locked laser module
CN116466494A (zh) 2016-12-16 2023-07-21 宽腾矽公司 紧密的光束整形及操纵总成
US10845308B2 (en) 2016-12-22 2020-11-24 Quantum-Si Incorporated Integrated photodetector with direct binning pixel
BR112020000826A2 (pt) 2017-07-24 2020-07-21 Quantum-Si Incorporated instrumento bio-optoeletrônico maciçamente paralelo portátil
TWI653449B (zh) * 2018-01-31 2019-03-11 國立交通大學 光子晶體與磁珠結合的螢光免疫檢測裝置和方法
DE102018202591A1 (de) * 2018-02-21 2019-08-22 Robert Bosch Gmbh Optisches System sowie ein Verfahren zur Herstellung eines optischen Systems
CA3067154A1 (en) 2018-03-29 2019-10-03 Illumina, Inc. Illumination for fluorescence imaging using objective lens
KR20210021018A (ko) 2018-06-15 2021-02-24 퀀텀-에스아이 인코포레이티드 펄스형 광학 소스들을 갖는 고급 분석 기기들을 위한 데이터 취득 제어
AU2019288394B2 (en) 2018-06-22 2025-01-30 Quantum-Si Incorporated Integrated photodetector with charge storage bin of varied detection time
US11255790B2 (en) 2019-01-08 2022-02-22 Boe Technology Group Co., Ltd. Fluid detection panel with filter structure and fluid detection device with filter structure
CN109632660B (zh) * 2019-01-17 2022-04-05 京东方科技集团股份有限公司 流体检测面板
CA3142922A1 (en) 2019-06-14 2020-12-17 Quantum-Si Incorporated Sliced grating coupler with increased beam alignment sensitivity
NL2023679B1 (en) * 2019-08-09 2021-04-13 Illumina Inc System and method for patterning flow cell substrates
KR20220137027A (ko) 2020-01-14 2022-10-11 퀀텀-에스아이 인코포레이티드 진폭 변조 레이저
DE102021133357A1 (de) 2021-12-15 2023-06-15 Endress+Hauser Conducta Gmbh+Co. Kg Sensorelement, Sensorsystem und Verfahren zum Herstellen des Sensorelements
TWI796944B (zh) * 2022-01-28 2023-03-21 國立中山大學 螢光增強基板及螢光檢測裝置
KR102935909B1 (ko) * 2023-07-27 2026-03-09 한국광기술원 라이다 장치 내 윈도우에 코팅되는 무반사 코팅층 및 그의 코팅방법

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4582809A (en) * 1982-06-14 1986-04-15 Myron J. Block Apparatus including optical fiber for fluorescence immunoassay
DE3680999D1 (de) * 1985-05-29 1991-09-26 Artificial Sensing Instr Asi A Optischer sensor zum selektiven nachweis von substanzen und zum nachweis von brechzahlaenderungen in messubstanzen.
WO1989007756A1 (fr) * 1988-02-14 1989-08-24 Walter Lukosz Procede optique integre d'interference
GB8807486D0 (en) * 1988-03-29 1988-05-05 Ares Serono Res & Dev Ltd Waveguide sensor
GB8827853D0 (en) * 1988-11-29 1988-12-29 Ares Serono Res & Dev Ltd Sensor for optical assay
US5082629A (en) * 1989-12-29 1992-01-21 The Board Of The University Of Washington Thin-film spectroscopic sensor
JPH05504626A (ja) * 1990-03-02 1993-07-15 ファイソンズ ピーエルシー 化学又は生化学試験に用いる試料セル
DE69128123T2 (de) * 1990-08-31 1998-03-05 Texas Instruments Inc Verfahren zum Herstellen selbst-ausrichtender bipolarer Transistoren mit Heteroübergang
DE4228853C2 (de) * 1991-09-18 1993-10-21 Schott Glaswerke Optischer Wellenleiter mit einem planaren oder nur geringfügig gewölbten Substrat und Verfahren zu dessen Herstellung sowie Verwendung eines solchen
US5294799A (en) * 1993-02-01 1994-03-15 Aslund Nils R D Apparatus for quantitative imaging of multiple fluorophores
US5418371A (en) * 1993-02-01 1995-05-23 Aslund; Nils R. D. Apparatus for quantitative imaging of multiple fluorophores using dual detectors
DE69526438T2 (de) * 1994-05-27 2002-10-31 Novartis Ag, Basel Verfahren zum nachweis abklingend angeregter lumineszenz

Also Published As

Publication number Publication date
HUT76407A (en) 1997-08-28
DE69526438D1 (de) 2002-05-23
AU2317995A (en) 1995-12-21
CN1149336A (zh) 1997-05-07
ZA954327B (en) 1995-11-27
TW295624B (da) 1997-01-11
CZ347196A3 (en) 1997-06-11
HU9603261D0 (en) 1997-01-28
CA2190643A1 (en) 1995-12-07
TW278135B (da) 1996-06-11
ATE172300T1 (de) 1998-10-15
DE69526438T2 (de) 2002-10-31
PL317379A1 (en) 1997-04-01
SK151296A3 (en) 1997-07-09
HUT76406A (en) 1997-08-28
JP2005326426A (ja) 2005-11-24
CA2190362A1 (en) 1995-12-07
SK151396A3 (en) 1997-07-09
PL317402A1 (en) 1997-04-14
EP0759159B1 (en) 1998-10-14
WO1995033198A1 (en) 1995-12-07
ES2174948T3 (es) 2002-11-16
FI964684A7 (fi) 1997-01-27
US5959292A (en) 1999-09-28
FI964664A7 (fi) 1997-01-24
KR970703527A (ko) 1997-07-03
CZ347296A3 (en) 1997-03-12
JP3645907B2 (ja) 2005-05-11
JPH10501616A (ja) 1998-02-10
ATE216491T1 (de) 2002-05-15
JPH10501617A (ja) 1998-02-10
CN1149335A (zh) 1997-05-07
DE69505370D1 (de) 1998-11-19
HU9603260D0 (en) 1997-01-28
WO1995033197A1 (en) 1995-12-07
EP0759159A1 (en) 1997-02-26
ZA954325B (en) 1995-11-27
MXPA96005828A (es) 2005-07-15
DE69505370T2 (de) 1999-04-01
FI964664A0 (fi) 1996-11-22
EP0760944B1 (en) 2002-04-17
IL113849A0 (en) 1995-08-31
IL113854A0 (en) 1995-08-31
FI964684A0 (fi) 1996-11-25
AU2734695A (en) 1995-12-21
US5822472A (en) 1998-10-13
EP0760944A1 (en) 1997-03-12
AU689604B2 (en) 1998-04-02

Similar Documents

Publication Publication Date Title
FI964664A0 (fi) Menetelmä aaltomaisesti lähetetyn luminanssin havaitsemiseksi
AU5763296A (en) Sensor platform and method for the parallel detection of a plurality of analytes using evanescently excited luminescence
SE9201984D0 (sv) Improvement in optical assays
WO2001092870A3 (de) Kit und verfahren zur multianalytbestimmung
ATE412171T1 (de) Faseroptische assay-vorrichtung auf der basis der phasenverschiebungs-interferometrie
SE9200917D0 (sv) Assay method
SE9503028D0 (sv) Method of analysing chemical and physical interactions at a sensor surface
ATE442579T1 (de) Verfahren und vorrichtung zur lumineszenzmessung
Hua et al. Integrated optical fluorescence multisensor for water pollution
WO2002059253A3 (en) Fluorescence detection system including a photonic band gap structure
ATE247826T1 (de) Verfahren zur herstellung eines sensitiven einschichtsystems zur messung der konzentration von analyten und ein mit diesem verfahren hergestelltes system
SE9403078D0 (sv) Milk assay
DE59806188D1 (de) Vorrichtung und verfahren zur durchführung von fluoreszenzimmunotests
DE69921821D1 (de) Optisches verfahren zur detektion von farbmarkiertem dieselkraftstoff in unmarkiertem dieselkraftstoff
WO2007082160A3 (en) Method for increasing signal intensity in an optical waveguide sensor
Kohls et al. Development and comparison of pH microoptodes for use in marine systems
RU2198394C2 (ru) Оптический биосенсор необратимых ингибиторов холинэстеразы в воздухе
KR970703526A (ko) 소실되어 여기된 발광의 검출방법(Process for detecting evanescently excited luminescence)
SE9102397D0 (sv) Assay method