ES2174948T3 - Proceso para detectar luminiscencia evanescentemente excitada en forma evanescente. - Google Patents

Proceso para detectar luminiscencia evanescentemente excitada en forma evanescente.

Info

Publication number
ES2174948T3
ES2174948T3 ES95922453T ES95922453T ES2174948T3 ES 2174948 T3 ES2174948 T3 ES 2174948T3 ES 95922453 T ES95922453 T ES 95922453T ES 95922453 T ES95922453 T ES 95922453T ES 2174948 T3 ES2174948 T3 ES 2174948T3
Authority
ES
Spain
Prior art keywords
luminiscence
layer
executively
excited
detecting
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES95922453T
Other languages
English (en)
Inventor
Gert L Duveneck
Dieter Neuschafer
Markus Ehrat
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novartis AG
Original Assignee
Novartis AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis AG filed Critical Novartis AG
Application granted granted Critical
Publication of ES2174948T3 publication Critical patent/ES2174948T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/75—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated
    • G01N21/77—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N21/645—Specially adapted constructive features of fluorimeters
    • G01N21/648—Specially adapted constructive features of fluorimeters using evanescent coupling or surface plasmon coupling for the excitation of fluorescence
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/75—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated
    • G01N21/77—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator
    • G01N21/7703—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator using reagent-clad optical fibres or optical waveguides
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/75—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated
    • G01N21/77—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator
    • G01N21/7703—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator using reagent-clad optical fibres or optical waveguides
    • G01N21/774—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator using reagent-clad optical fibres or optical waveguides the reagent being on a grating or periodic structure
    • G01N21/7743—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator using reagent-clad optical fibres or optical waveguides the reagent being on a grating or periodic structure the reagent-coated grating coupling light in or out of the waveguide

Landscapes

  • Chemical & Material Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Plasma & Fusion (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Manufacture, Treatment Of Glass Fibers (AREA)
  • Testing, Inspecting, Measuring Of Stereoscopic Televisions And Televisions (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)

Abstract

LA INVENCION SE REFIERE A UN PROCESO PARA DETECTAR LUMINISCENCIA CON UNA PLATAFORMA DE SENSORES OPTICOS DIELECTRICOS PLANA QUE CONSTA DE UN SUBSTRATO TRANSPARENTE (A) AL CUAL SE APLICA UNA CAPA DE GUIA DE ONDAS FINA, TRANSPARENTE (B), LA PLATAFORMA DETECTORA ESTA PROVISTA DE UNA REJILLA PARA EL ACOPLAMIENTO DE ENTRADA DE LA LUZ DE EXCITACION Y EL INDICE REFRACTIVO DEL SUBSTRATO (A) ES MENOR QUE EL INDICE REFRACTIVO DE LA CAPA DE GUIAS DE ONDAS (B), MEDIANTE LA PUESTA EN CONTACTO DE UNA MUESTRA DE LIQUIDO CON LA CAPA (B), Y MIDIENDO LA LUMINISCENCIA PRODUCIDA POR SUBSTANCIAS QUE TIENEN PROPIEDADES DE LUMINISCENCIA EN LA MUESTRA, O POR SUBSTANCIAS QUE TIENEN PROPIEDADES DE LUMINISCENCIA INMOVILIZADAS EN LA CAPA (B), OPTOELECTRONICAMENTE. LA INVENCION TAMBIEN SE REFIERE AL USO DEL PROCESO EN LA DETECCION CUANTITATIVA DE AFINIDAD Y AL USO DEL MISMO PARA LA DETERMINACION CUANTITATIVA DE CONSTITUYENTES LUMINISCENTES EN SOLUCIONES OPTICAMENTE TURBIAS.
ES95922453T 1994-05-27 1995-05-17 Proceso para detectar luminiscencia evanescentemente excitada en forma evanescente. Expired - Lifetime ES2174948T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH164394 1994-05-27

Publications (1)

Publication Number Publication Date
ES2174948T3 true ES2174948T3 (es) 2002-11-16

Family

ID=4215258

Family Applications (1)

Application Number Title Priority Date Filing Date
ES95922453T Expired - Lifetime ES2174948T3 (es) 1994-05-27 1995-05-17 Proceso para detectar luminiscencia evanescentemente excitada en forma evanescente.

Country Status (21)

Country Link
US (2) US5822472A (es)
EP (2) EP0759159B1 (es)
JP (3) JP3645907B2 (es)
KR (1) KR970703527A (es)
CN (2) CN1149335A (es)
AT (2) ATE216491T1 (es)
AU (2) AU689604B2 (es)
CA (2) CA2190362A1 (es)
CZ (2) CZ347296A3 (es)
DE (2) DE69505370T2 (es)
DK (1) DK0760944T3 (es)
ES (1) ES2174948T3 (es)
FI (2) FI964664A7 (es)
HU (2) HUT76406A (es)
IL (2) IL113854A0 (es)
MX (1) MXPA96005828A (es)
PL (2) PL317379A1 (es)
SK (2) SK151296A3 (es)
TW (2) TW295624B (es)
WO (2) WO1995033197A1 (es)
ZA (2) ZA954327B (es)

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