DK0761672T3 - Nye cephalosporiner, som i 7-stilling indeholder en substitueret benzyloxyiminogruppe, fremgangsmåder og mellemprodukter og deres anvendelse som lægemidler - Google Patents

Nye cephalosporiner, som i 7-stilling indeholder en substitueret benzyloxyiminogruppe, fremgangsmåder og mellemprodukter og deres anvendelse som lægemidler

Info

Publication number
DK0761672T3
DK0761672T3 DK96401777T DK96401777T DK0761672T3 DK 0761672 T3 DK0761672 T3 DK 0761672T3 DK 96401777 T DK96401777 T DK 96401777T DK 96401777 T DK96401777 T DK 96401777T DK 0761672 T3 DK0761672 T3 DK 0761672T3
Authority
DK
Denmark
Prior art keywords
intermediates
drugs
methods
novel cephalosporins
cephalosporins containing
Prior art date
Application number
DK96401777T
Other languages
Danish (da)
English (en)
Inventor
Jozsef Aszodi
Patrick Fauveau
Daniel Humbert
Original Assignee
Aventis Pharma Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aventis Pharma Sa filed Critical Aventis Pharma Sa
Application granted granted Critical
Publication of DK0761672T3 publication Critical patent/DK0761672T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C239/00—Compounds containing nitrogen-to-halogen bonds; Hydroxylamino compounds or ethers or esters thereof
    • C07C239/08—Hydroxylamino compounds or their ethers or esters
    • C07C239/20—Hydroxylamino compounds or their ethers or esters having oxygen atoms of hydroxylamino groups etherified
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/587—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with aliphatic hydrocarbon radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms, said aliphatic radicals being substituted in the alpha-position to the ring by a hetero atom, e.g. with m >= 0, Z being a singly or a doubly bound hetero atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Communicable Diseases (AREA)
  • Animal Behavior & Ethology (AREA)
  • Oncology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
DK96401777T 1995-08-16 1996-08-13 Nye cephalosporiner, som i 7-stilling indeholder en substitueret benzyloxyiminogruppe, fremgangsmåder og mellemprodukter og deres anvendelse som lægemidler DK0761672T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9509822A FR2737893B1 (fr) 1995-08-16 1995-08-16 Nouvelles cephalosporines comportant en position 7, un radical benzyloxyimino substitue, leur procede et intermediaires de preparation, leur application comme medicaments

Publications (1)

Publication Number Publication Date
DK0761672T3 true DK0761672T3 (da) 2002-03-11

Family

ID=9481928

Family Applications (1)

Application Number Title Priority Date Filing Date
DK96401777T DK0761672T3 (da) 1995-08-16 1996-08-13 Nye cephalosporiner, som i 7-stilling indeholder en substitueret benzyloxyiminogruppe, fremgangsmåder og mellemprodukter og deres anvendelse som lægemidler

Country Status (15)

Country Link
EP (1) EP0761672B1 (de)
JP (1) JPH0959281A (de)
KR (1) KR970010775A (de)
CN (2) CN1152575A (de)
AT (1) ATE208396T1 (de)
AU (1) AU708973B2 (de)
CA (1) CA2183469A1 (de)
DE (1) DE69616702T2 (de)
DK (1) DK0761672T3 (de)
EA (1) EA000165B1 (de)
ES (1) ES2164853T3 (de)
FR (1) FR2737893B1 (de)
HU (1) HUP9602254A3 (de)
PT (1) PT761672E (de)
ZA (1) ZA966465B (de)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL139470A0 (en) * 1998-05-11 2001-11-25 Takeda Chemical Industries Ltd Oxyiminoalkanoic acid derivatives

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2663332B1 (fr) * 1990-06-15 1997-11-07 Roussel Uclaf Nouvelles cephalosporines comportant en position 3 un radical propenyle substitue par un ammonium quaternaire, leur procede de preparation, leur application comme medicaments, les compositions les renfermant et les nouveaux intermediaires obtenus.
FR2684995A1 (en) * 1991-12-12 1993-06-18 Roussel Uclaf Cephalosporins containing a ( alpha -carboxy-3,4-dihydroxybenzyloxyimino) group, preparation process and intermediates, application as medicaments and pharmaceutical compositions
EP0551034B1 (de) * 1991-12-12 2000-09-20 Hoechst Marion Roussel Antibiotische Cephalosporine einen substituierten Benzyloxyimino-Radikal in Position 7 tragend
KR100257130B1 (ko) * 1993-09-11 2000-05-15 성재갑 신규 세팔로스포린계 항생제 및 이의 제조방법

Also Published As

Publication number Publication date
AU6209896A (en) 1997-02-20
HU9602254D0 (en) 1996-10-28
HUP9602254A2 (en) 1997-05-28
KR970010775A (ko) 1997-03-27
EP0761672A1 (de) 1997-03-12
CA2183469A1 (fr) 1997-02-17
ES2164853T3 (es) 2002-03-01
CN1152575A (zh) 1997-06-25
EA199600055A1 (ru) 1997-03-31
EP0761672B1 (de) 2001-11-07
FR2737893B1 (fr) 1997-09-12
AU708973B2 (en) 1999-08-19
PT761672E (pt) 2002-04-29
FR2737893A1 (fr) 1997-02-21
DE69616702D1 (de) 2001-12-13
ZA966465B (en) 1997-07-30
EA000165B1 (ru) 1998-10-29
CN1388120A (zh) 2003-01-01
JPH0959281A (ja) 1997-03-04
ATE208396T1 (de) 2001-11-15
DE69616702T2 (de) 2002-08-01
HUP9602254A3 (en) 2001-04-28

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