ATE208396T1 - Cephalosporine die im stellung 7 ein substituiertes benzyloxyiminoradikal enthalten, verfahren zu ihrer herstellung und zwischenverbindungen zu ihrer herstellung, ihre anwendung als medikamente - Google Patents

Cephalosporine die im stellung 7 ein substituiertes benzyloxyiminoradikal enthalten, verfahren zu ihrer herstellung und zwischenverbindungen zu ihrer herstellung, ihre anwendung als medikamente

Info

Publication number
ATE208396T1
ATE208396T1 AT96401777T AT96401777T ATE208396T1 AT E208396 T1 ATE208396 T1 AT E208396T1 AT 96401777 T AT96401777 T AT 96401777T AT 96401777 T AT96401777 T AT 96401777T AT E208396 T1 ATE208396 T1 AT E208396T1
Authority
AT
Austria
Prior art keywords
production
benzyloxyiminoradical
cephalosporins
medications
substituted
Prior art date
Application number
AT96401777T
Other languages
English (en)
Inventor
Jozsef Aszodi
Patrick Fauveau
Daniel Humbert
Original Assignee
Aventis Pharma Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aventis Pharma Sa filed Critical Aventis Pharma Sa
Application granted granted Critical
Publication of ATE208396T1 publication Critical patent/ATE208396T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C239/00—Compounds containing nitrogen-to-halogen bonds; Hydroxylamino compounds or ethers or esters thereof
    • C07C239/08—Hydroxylamino compounds or their ethers or esters
    • C07C239/20—Hydroxylamino compounds or their ethers or esters having oxygen atoms of hydroxylamino groups etherified
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/587—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with aliphatic hydrocarbon radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms, said aliphatic radicals being substituted in the alpha-position to the ring by a hetero atom, e.g. with m >= 0, Z being a singly or a doubly bound hetero atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Communicable Diseases (AREA)
  • Animal Behavior & Ethology (AREA)
  • Oncology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
AT96401777T 1995-08-16 1996-08-13 Cephalosporine die im stellung 7 ein substituiertes benzyloxyiminoradikal enthalten, verfahren zu ihrer herstellung und zwischenverbindungen zu ihrer herstellung, ihre anwendung als medikamente ATE208396T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9509822A FR2737893B1 (fr) 1995-08-16 1995-08-16 Nouvelles cephalosporines comportant en position 7, un radical benzyloxyimino substitue, leur procede et intermediaires de preparation, leur application comme medicaments

Publications (1)

Publication Number Publication Date
ATE208396T1 true ATE208396T1 (de) 2001-11-15

Family

ID=9481928

Family Applications (1)

Application Number Title Priority Date Filing Date
AT96401777T ATE208396T1 (de) 1995-08-16 1996-08-13 Cephalosporine die im stellung 7 ein substituiertes benzyloxyiminoradikal enthalten, verfahren zu ihrer herstellung und zwischenverbindungen zu ihrer herstellung, ihre anwendung als medikamente

Country Status (15)

Country Link
EP (1) EP0761672B1 (de)
JP (1) JPH0959281A (de)
KR (1) KR970010775A (de)
CN (2) CN1152575A (de)
AT (1) ATE208396T1 (de)
AU (1) AU708973B2 (de)
CA (1) CA2183469A1 (de)
DE (1) DE69616702T2 (de)
DK (1) DK0761672T3 (de)
EA (1) EA000165B1 (de)
ES (1) ES2164853T3 (de)
FR (1) FR2737893B1 (de)
HU (1) HUP9602254A3 (de)
PT (1) PT761672E (de)
ZA (1) ZA966465B (de)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6251926B1 (en) * 1998-05-11 2001-06-26 Takeda Chemical Industries, Ltd. Oxyiminoalkanoic acid derivatives with hypoglycemic and hypolipidemic activity

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2663332B1 (fr) * 1990-06-15 1997-11-07 Roussel Uclaf Nouvelles cephalosporines comportant en position 3 un radical propenyle substitue par un ammonium quaternaire, leur procede de preparation, leur application comme medicaments, les compositions les renfermant et les nouveaux intermediaires obtenus.
FR2684995A1 (en) * 1991-12-12 1993-06-18 Roussel Uclaf Cephalosporins containing a ( alpha -carboxy-3,4-dihydroxybenzyloxyimino) group, preparation process and intermediates, application as medicaments and pharmaceutical compositions
KR0143092B1 (ko) * 1991-12-12 1998-07-15 장-끌로드 비에이으포스 7 위치에 치환된 벤질옥시이미노 라디칼을 함유하는 신규 세팔로스포린, 그의 제조 방법 및 의약으로서의 그의 용도
KR100257130B1 (ko) * 1993-09-11 2000-05-15 성재갑 신규 세팔로스포린계 항생제 및 이의 제조방법

Also Published As

Publication number Publication date
PT761672E (pt) 2002-04-29
DK0761672T3 (da) 2002-03-11
FR2737893B1 (fr) 1997-09-12
AU708973B2 (en) 1999-08-19
DE69616702D1 (de) 2001-12-13
EA199600055A1 (ru) 1997-03-31
CA2183469A1 (fr) 1997-02-17
EP0761672B1 (de) 2001-11-07
KR970010775A (ko) 1997-03-27
EA000165B1 (ru) 1998-10-29
EP0761672A1 (de) 1997-03-12
HUP9602254A3 (en) 2001-04-28
FR2737893A1 (fr) 1997-02-21
CN1388120A (zh) 2003-01-01
AU6209896A (en) 1997-02-20
HU9602254D0 (en) 1996-10-28
HUP9602254A2 (en) 1997-05-28
ES2164853T3 (es) 2002-03-01
DE69616702T2 (de) 2002-08-01
JPH0959281A (ja) 1997-03-04
ZA966465B (en) 1997-07-30
CN1152575A (zh) 1997-06-25

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Legal Events

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UEP Publication of translation of european patent specification
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