DK0776376T3 - Anvendelse af RNA-polymerase til forbedring af en nucleinsyreamplifikationsproces - Google Patents

Anvendelse af RNA-polymerase til forbedring af en nucleinsyreamplifikationsproces

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Publication number
DK0776376T3
DK0776376T3 DK95929679T DK95929679T DK0776376T3 DK 0776376 T3 DK0776376 T3 DK 0776376T3 DK 95929679 T DK95929679 T DK 95929679T DK 95929679 T DK95929679 T DK 95929679T DK 0776376 T3 DK0776376 T3 DK 0776376T3
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DK
Denmark
Prior art keywords
template
rna
nucleic acid
dna
reagents
Prior art date
Application number
DK95929679T
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English (en)
Inventor
Roy Sooknanan
Original Assignee
Organon Teknika Bv
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Publication date
Application filed by Organon Teknika Bv filed Critical Organon Teknika Bv
Application granted granted Critical
Publication of DK0776376T3 publication Critical patent/DK0776376T3/da

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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6844Nucleic acid amplification reactions
    • C12Q1/6865Promoter-based amplification, e.g. nucleic acid sequence amplification [NASBA], self-sustained sequence replication [3SR] or transcription-based amplification system [TAS]

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  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Biophysics (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
DK95929679T 1994-07-15 1995-07-13 Anvendelse af RNA-polymerase til forbedring af en nucleinsyreamplifikationsproces DK0776376T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US27525094A 1994-07-15 1994-07-15
PCT/CA1995/000423 WO1996002668A1 (en) 1994-07-15 1995-07-13 Use of rna polymerase to improve nucleic acid amplification process

Publications (1)

Publication Number Publication Date
DK0776376T3 true DK0776376T3 (da) 2002-02-18

Family

ID=23051486

Family Applications (1)

Application Number Title Priority Date Filing Date
DK95929679T DK0776376T3 (da) 1994-07-15 1995-07-13 Anvendelse af RNA-polymerase til forbedring af en nucleinsyreamplifikationsproces

Country Status (12)

Country Link
US (1) US6025134A (da)
EP (1) EP0776376B1 (da)
JP (1) JP3881009B2 (da)
KR (1) KR100392551B1 (da)
AT (1) ATE209258T1 (da)
AU (1) AU711115B2 (da)
CA (1) CA2195209C (da)
DE (1) DE69524105T2 (da)
DK (1) DK0776376T3 (da)
ES (1) ES2168380T3 (da)
PT (1) PT776376E (da)
WO (1) WO1996002668A1 (da)

Families Citing this family (87)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5712127A (en) * 1996-04-29 1998-01-27 Genescape Inc. Subtractive amplification
US6225062B1 (en) 1996-11-12 2001-05-01 Visible Genetics Inc. Method and kit for direct isothermal sequencing of nucleic acids
ZA989950B (en) * 1997-11-17 1999-05-04 Akzo Nobel Nv Transcription based amplification of double stranded DNA targets
KR100440044B1 (ko) * 1998-02-27 2004-07-14 팸진 비.브이. 핵산의 비특이적 증폭방법
AU4515699A (en) * 1998-06-26 2000-01-17 Akzo Nobel N.V. Tagging of rna amplicons generated by transcription-based amplification
ATE330031T1 (de) * 1998-07-31 2006-07-15 Gen Probe Inc Reversibel inhibierende sonden
WO2003064679A2 (en) 2002-01-30 2003-08-07 Id Biomedical Corporation Methods for detecting vancomycin-resistant microorganisms and compositions therefor
EP1558758B1 (en) 2002-05-17 2009-09-23 The Government of the United States of America as Represented by the Secretary of the Department of Health and Human Services, Molecular identification of aspergillus species
US20040018494A1 (en) * 2002-07-25 2004-01-29 Shurtliff Roxanne N Isothermal transcription based amplification assay for detection and quantification of guanylyl cyclase C
EP1545575A4 (en) 2002-09-19 2006-04-05 Us Gov Health & Human Serv P. ARIASI POLYPEPTIDE, P. PERNICIOSUS POLYPEPTIDES AND METHOD OF USE
ES2447843T3 (es) 2002-10-29 2014-03-13 The Government Of The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services Polip�ptidos de Lutzomyia longipalpis y m�todos de uso
EP1945780B1 (en) 2005-10-14 2015-09-16 THE GOVERNMENT OF THE UNITED STATES OF AMERICA as represented by THE SECRETARY OF THE DEPARTMENT OF HEALTH AND HUMAN SERVICES Rabies virus vector systems and compositions and methods thereof
CA3031887C (en) 2006-02-13 2023-02-07 The Government Of The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services, Centers For Disease Control And Prevention Primers and probes for detection and discrimination of types and subtypes of influenza viruses
EP2441469A1 (en) 2006-03-14 2012-04-18 Oregon Health and Science University Methods for producing an immune response to tuberculosis
KR101523391B1 (ko) 2006-12-27 2015-05-27 에모리 유니버시티 감염 및 종양 치료를 위한 조성물 및 방법
WO2008106551A2 (en) 2007-02-28 2008-09-04 The Govt. Of The U.S.A. As Represented By The Secretary Of The Dept. Of Health & Human Serv. Brachyury polypeptides and methods for use
WO2009125303A2 (en) 2008-04-10 2009-10-15 Genenews Corporation Method and apparatus for determining a probability of colorectal cancer in a subject
JP2012503206A (ja) 2008-09-22 2012-02-02 オレゴン ヘルス アンド サイエンス ユニバーシティ Mycobacteriumtuberculosis感染を検出するための方法
MX2011005691A (es) 2008-11-28 2011-07-20 Univ Emory Metodos para el tratamiento de infecciones y tumores.
WO2010096713A2 (en) 2009-02-20 2010-08-26 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Method for the diagnosis of age-associated vascular disorders
WO2010138908A1 (en) 2009-05-29 2010-12-02 Ventana Medical Systems, Inc. Igfir gene copy number as a prognostic marker in a non-small cell lung cancer
CA2763321C (en) 2009-05-29 2018-10-16 Ventana Medical Systems, Inc. Methods of scoring gene copy number in a biological sample using in situ hybridization
US8835117B2 (en) 2009-05-29 2014-09-16 The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services, Centers For Disease Control And Prevention Nucleic acids for detection and discrimination of genotypes of Chlamydophila psittaci
CA2774636C (en) 2009-09-25 2019-05-21 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Neutralizing antibodies to hiv-1 and their use
WO2011047340A1 (en) 2009-10-16 2011-04-21 The United States Of America, As Represented By The Secretary, Department Of Health & Human Services Insertion of foreign genes in rubella virus and their stable expression in a live, attenuated viral vaccine
CN102713629B (zh) 2009-11-20 2016-02-24 俄勒冈健康科学大学 用于检测结核分枝杆菌感染的方法
WO2011133474A2 (en) 2010-04-18 2011-10-27 Beth Israel Deaconess Medical Center Methods of predicting predisposition to or risk of kidney disease
WO2011133433A2 (en) 2010-04-16 2011-10-27 The Government Of The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services, Centers For Disease Control And Prevention Real time pcr assay for detection of bacterial respiratory pathogens
EP2582727B8 (en) 2010-06-16 2017-04-19 University of Pittsburgh- Of the Commonwealth System of Higher Education Antibodies to endoplasmin and their use
WO2012006056A2 (en) 2010-06-29 2012-01-12 Oregon Health & Science University Ccr6 as a biomarker of alzheimer's disease
ES2657233T3 (es) 2010-08-30 2018-03-02 Dow Agrosciences, Llc Potenciador viral baciliforme de la caña de azúcar (SCBV) y su uso en la genómica vegetal funcional
AR082785A1 (es) 2010-08-30 2013-01-09 Agrigenetics Inc Plataforma de activacion por marcado para genes de maiz y poblaciones y plantas marcadas resultantes
KR20140006898A (ko) 2011-01-25 2014-01-16 알막 다이아그노스틱스 리미티드 결장암 유전자 발현 시그니처 및 이용 방법
US9150644B2 (en) 2011-04-12 2015-10-06 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Human monoclonal antibodies that bind insulin-like growth factor (IGF) I and II
ES2597032T3 (es) 2011-05-04 2017-01-13 HTG Molecular Diagnostics, Inc Mejoras en un ensayo cuantitativo de protección contra la nucleasa (qNPA) y secuenciación (qNPS)
WO2013006684A1 (en) 2011-07-05 2013-01-10 The Gov. Of The U.S.A. As Represented By The Secretary Of The Dept. Of Health And Human Services. Hiv-1 genotyping assay for global surveillance of hiv-1 drug resistance
WO2013049535A2 (en) 2011-09-30 2013-04-04 The United States Of America, As Represented By The Secretary, Department Of Health & Human Services Influenza vaccine
WO2013071954A1 (en) 2011-11-15 2013-05-23 Université Libre de Bruxelles Streptococcus pneumoniae detection in blood
AU2013202941B2 (en) 2012-02-29 2015-06-25 Dow Agrosciences Llc Sugarcane bacilliform viral (SCBV) enhancer and its use in plant functional genomics
CA2866185C (en) 2012-03-23 2021-04-06 The Government Of The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services Pathogenic phlebovirus isolates and compositions and methods of use
WO2013148147A1 (en) 2012-03-26 2013-10-03 The U.S.A., As Represented By The Secretary Dept. Of Health And Human Services Dna methylation analysis for the diagnosis, prognosis and treatment of adrenal neoplasms
US9566329B2 (en) 2012-04-06 2017-02-14 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Live, attenuated rubella vector to express vaccine antigens
WO2013162828A1 (en) 2012-04-27 2013-10-31 The United States Of America, As Represented By The Secretary, Department Of Health & Human Services Use of cpg oligonucleotides co-formulated with an antibiotic to accelarate wound healing
WO2013165551A1 (en) 2012-05-03 2013-11-07 The Government Of The Usa As Represented By The Secretary Of The Department Of Health And Human Services Methods of detecting influenza virus
US9394574B2 (en) 2012-06-12 2016-07-19 The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services Methods for detecting Legionella nucleic acids in a sample
WO2013192100A1 (en) 2012-06-18 2013-12-27 The United States Of America, As Represented By The Secretary, Department Of Health & Human Services Methods and compositions for detecting jc virus
WO2014043518A1 (en) 2012-09-14 2014-03-20 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Brachyury protein, non-poxvirus non-yeast vectors encoding brachyury protein, and their use
US9775895B2 (en) 2012-12-12 2017-10-03 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services HIV therapeutics and methods of making and using same
EP2951290B1 (en) 2013-02-01 2017-11-29 The United States of America, as represented by The Secretary, Department of Health and Human Services Method for generating retinal pigment epithelium (rpe) cells from induced pluripotent stem cells (ipscs)
WO2014126921A1 (en) 2013-02-12 2014-08-21 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Monoclonal antibodies that neutralize norovirus
WO2014152155A1 (en) 2013-03-14 2014-09-25 The Broad Institute, Inc. Massively multiplexed rna sequencing
US20160083698A1 (en) 2013-04-19 2016-03-24 The Regents Of The University Of California Lone star virus
EP2994163B1 (en) 2013-05-09 2019-08-28 The United States of America, as represented by The Secretary, Department of Health and Human Services Single-domain vhh antibodies directed to norovirus gi.1 and gii.4 and their use
WO2015061475A2 (en) 2013-10-22 2015-04-30 THE GOVERNMENT OF THE USA as represented by THE SECRETARY OF THE DEPARTMENT OF HEATLH AND HUMAN SERV Compositions and methods for detection and discrimination of influenza viruses
US10398772B2 (en) 2014-01-08 2019-09-03 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Ras pathways as markers of protection against HIV and methods to improve vaccine efficacy
US20170058366A1 (en) 2014-02-21 2017-03-02 The United States of America, as represented by th e Secretary, Dept. of Health and Human Services Hiv-2 nucleic acids and methods of detection
WO2015160536A1 (en) 2014-04-14 2015-10-22 The United States Of America, As Represented By The Secretary Department Of Health And Human Services Methods for rapid detection and identification of viral nucleic acids
WO2015199976A1 (en) 2014-06-24 2015-12-30 The United States Of America, As Represented By The Secretary, Department Of Health & Human Services Target activated microdissection
US20170252364A1 (en) 2014-07-30 2017-09-07 Mor Research Applications Ltd. Compositions for treatment of acute lymphoblastic leukemia and methods of use thereof
JP6811706B2 (ja) 2014-07-31 2021-01-13 ザ ホンコン ユニヴァーシティ オブ サイエンス アンド テクノロジー Epha4に対するヒトモノクローナル抗体及びそれらの使用
WO2016089920A1 (en) 2014-12-01 2016-06-09 The Broad Institute, Inc. Method for in situ determination of nucleic acid proximity
WO2016090170A1 (en) 2014-12-05 2016-06-09 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services A potent anti-influenza a neuraminidase subtype n1 antibody
WO2016134144A1 (en) 2015-02-20 2016-08-25 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Methods and reagents for detecting ebola virus
US11873483B2 (en) 2015-03-11 2024-01-16 The Broad Institute, Inc. Proteomic analysis with nucleic acid identifiers
WO2017031370A1 (en) 2015-08-18 2017-02-23 The Broad Institute, Inc. Methods and compositions for altering function and structure of chromatin loops and/or domains
EP3359651A1 (en) 2015-10-05 2018-08-15 THE UNITED STATES OF AMERICA, represented by the S Human rota virus g9p[6]strain and use as a vaccine
WO2017192589A1 (en) 2016-05-02 2017-11-09 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Neutralizing antibodies to influenza ha and their use and identification
US11155885B2 (en) 2016-05-20 2021-10-26 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Real-time reverse transcriptase-polymerase chain reaction assay with modified probe for the diagnosis of rabies viruses and other lyssaviruses
US11248272B2 (en) 2016-06-27 2022-02-15 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Methods and compositions for influenza a virus subtyping
US12209292B2 (en) 2016-08-26 2025-01-28 The Broad Institute, Inc. Nucleic acid amplification assays for detection of pathogens
PE20191767A1 (es) 2016-12-06 2019-12-17 Univ Oregon State Composiciones y metodos para la produccion incrementada de enduracina en una cepa geneticamente modificada de streptomyces fungicidicus
US11708613B2 (en) 2017-05-03 2023-07-25 The United States of America, as Represened by the Secretary, Department of Health and Human Services Rapid detection of Zika virus by reverse transcription loop-mediated isothermal amplification
US11466329B2 (en) 2017-06-14 2022-10-11 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Detection of blaIMP antibacterial resistance genes
GB201710838D0 (en) 2017-07-05 2017-08-16 Ucl Business Plc Bispecific antibodies
DK4060041T5 (en) 2017-09-25 2024-07-22 Fred Hutchinson Cancer Center High efficiency targeted in situ genome-wide profiling
WO2019071054A1 (en) 2017-10-04 2019-04-11 The Broad Institute, Inc. METHODS AND COMPOSITIONS FOR MODIFYING THE FUNCTION AND STRUCTURE OF BUCKLES AND / OR CHROMATIN DOMAINS
WO2019133727A1 (en) 2017-12-29 2019-07-04 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Universal influenza virus probe set for enrichment of any influenza virus nucleic acid
WO2019152860A1 (en) 2018-02-02 2019-08-08 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Random amplification methods for extremely low input nucleic acids
JP7569781B2 (ja) 2018-07-27 2024-10-18 アペルタ バイオサイエンシズ,エルエルシー デモデックスにより誘発される眼の異常および顔面の異常を治療するためのスピノシン配合
US12188099B2 (en) 2018-12-12 2025-01-07 University Of Pittsburgh-Of The Commonwealth System Of Higher Education Integrated proviral sequencing assay
US20220262462A1 (en) 2019-04-10 2022-08-18 University Of Pittsburgh - Of The Commonwealth System Of Higher Education Computational filtering of methylated sequence data for predictive modeling
EP3976764B1 (en) 2019-05-30 2025-07-23 Viti, Inc. Methods for detecting a mycobacterium tuberculosis infection
WO2021016374A1 (en) 2019-07-23 2021-01-28 Snapdna System and method for detecting and monitoring pathogens
US11844800B2 (en) 2019-10-30 2023-12-19 Massachusetts Institute Of Technology Methods and compositions for predicting and preventing relapse of acute lymphoblastic leukemia
WO2022056078A1 (en) 2020-09-11 2022-03-17 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Rnase h-assisted detection assay for rna (radar)
IL308870A (en) 2021-05-26 2024-01-01 Centarix Biotech Ltd Methods for identifying critically short telomeres
WO2024191684A1 (en) 2023-03-10 2024-09-19 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Detection of hepatitis c virus ribonucleic acid from whole blood using reverse transcription loop-mediated isothermal amplification

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1340807C (en) * 1988-02-24 1999-11-02 Lawrence T. Malek Nucleic acid amplification process
US5130238A (en) * 1988-06-24 1992-07-14 Cangene Corporation Enhanced nucleic acid amplification process
WO1991001384A1 (en) * 1989-07-11 1991-02-07 Gen-Probe, Incorporated Nucleic acid sequence amplification methods utilizing a transcription complex
WO1991004340A1 (en) * 1989-09-20 1991-04-04 Cambridge Biotech Corporation In vitro, isothermal nucleic acid amplification
DE69029401T2 (de) * 1989-09-21 1997-07-10 Camborne Ind Plc Wiedergewinnung von schrott

Also Published As

Publication number Publication date
EP0776376B1 (en) 2001-11-21
DE69524105D1 (de) 2002-01-03
CA2195209A1 (en) 1996-02-01
AU3336695A (en) 1996-02-16
PT776376E (pt) 2002-05-31
ATE209258T1 (de) 2001-12-15
ES2168380T3 (es) 2002-06-16
US6025134A (en) 2000-02-15
DE69524105T2 (de) 2002-07-18
JP3881009B2 (ja) 2007-02-14
WO1996002668A1 (en) 1996-02-01
AU711115B2 (en) 1999-10-07
EP0776376A1 (en) 1997-06-04
JPH11505402A (ja) 1999-05-21
KR100392551B1 (ko) 2003-10-30
CA2195209C (en) 2008-09-23

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