DK0789767T3 - Fremgangsmåde til fremstilling af oprensede papilomavirusproteiner - Google Patents

Fremgangsmåde til fremstilling af oprensede papilomavirusproteiner

Info

Publication number
DK0789767T3
DK0789767T3 DK95942431T DK95942431T DK0789767T3 DK 0789767 T3 DK0789767 T3 DK 0789767T3 DK 95942431 T DK95942431 T DK 95942431T DK 95942431 T DK95942431 T DK 95942431T DK 0789767 T3 DK0789767 T3 DK 0789767T3
Authority
DK
Denmark
Prior art keywords
papilomavirus
proteins
purified
preparation
purified papilomavirus
Prior art date
Application number
DK95942431T
Other languages
Danish (da)
English (en)
Inventor
Kathrin U Jansen
James C Cook Iii
Hugh A George
Kathryn J Hofmann
Joseph G Joyce
Henry Z Markus
Loren D Schultz
Ernest D Lehman
Original Assignee
Merck & Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck & Co Inc filed Critical Merck & Co Inc
Application granted granted Critical
Publication of DK0789767T3 publication Critical patent/DK0789767T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011—Details
    • C12N2710/20011—Papillomaviridae
    • C12N2710/20022—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011—Details
    • C12N2710/20011—Papillomaviridae
    • C12N2710/20023—Virus like particles [VLP]

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Virology (AREA)
  • Medicinal Chemistry (AREA)
  • Oncology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Communicable Diseases (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Genetics & Genomics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
DK95942431T 1994-11-14 1995-11-13 Fremgangsmåde til fremstilling af oprensede papilomavirusproteiner DK0789767T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US33936894A 1994-11-14 1994-11-14
PCT/US1995/015027 WO1996015247A1 (en) 1994-11-14 1995-11-13 Purified papillomavirus proteins

Publications (1)

Publication Number Publication Date
DK0789767T3 true DK0789767T3 (da) 2003-10-20

Family

ID=23328696

Family Applications (1)

Application Number Title Priority Date Filing Date
DK95942431T DK0789767T3 (da) 1994-11-14 1995-11-13 Fremgangsmåde til fremstilling af oprensede papilomavirusproteiner

Country Status (23)

Country Link
EP (1) EP0789767B1 (de)
JP (1) JPH11500002A (de)
KR (1) KR987000420A (de)
CN (1) CN1173203A (de)
AR (1) AR004464A1 (de)
AT (1) ATE245192T1 (de)
AU (1) AU708737B2 (de)
BR (1) BR9510520A (de)
CZ (1) CZ145297A3 (de)
DE (1) DE69531308T2 (de)
DK (1) DK0789767T3 (de)
ES (1) ES2201129T3 (de)
FI (1) FI972030A7 (de)
HR (1) HRP950557A2 (de)
HU (1) HUT77559A (de)
MX (1) MX9703570A (de)
NZ (1) NZ298224A (de)
PT (1) PT789767E (de)
RU (1) RU2161651C2 (de)
SK (1) SK281878B6 (de)
UA (1) UA35639C2 (de)
WO (1) WO1996015247A1 (de)
YU (1) YU71195A (de)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6153201A (en) * 1993-03-09 2000-11-28 University Of Rochester Oral immunization with papillomavirus virus-like particles
NZ293461A (en) * 1994-09-22 1998-04-27 Merck & Co Inc Dna encoding human papillomavirus type 6a, compounds derived therefrom
GB9621091D0 (en) 1996-10-09 1996-11-27 Fondation Pour Le Perfectionem Attenuated microorganisms strains and their uses
JP4598201B2 (ja) * 1997-04-08 2010-12-15 メルク・シャープ・エンド・ドーム・コーポレイション 安定化ヒトパピローマウイルス製剤
AU760633B2 (en) * 1998-08-14 2003-05-22 Merck Sharp & Dohme Corp. Process for purifying human papillomavirus virus-like particles
AUPP765398A0 (en) * 1998-12-11 1999-01-14 University Of Queensland, The Treatment of papillomavirus infections
DE60040727D1 (de) 1999-02-05 2008-12-18 Merck & Co Inc Menschliche papillomavirus impfstoff-formulierungen
GB0206360D0 (en) 2002-03-18 2002-05-01 Glaxosmithkline Biolog Sa Viral antigens
CA2482512C (en) 2002-04-30 2011-09-20 Oncolytics Biotech Inc. Improved viral purification methods
US7276243B2 (en) * 2003-03-24 2007-10-02 Merck & Co., Inc. Optimized expression of HPV31 L1 in yeast
RU2251699C1 (ru) * 2003-09-25 2005-05-10 Киселев Всеволод Иванович Способ ранней и доклинической диагностики цервикального рака
MY140664A (en) 2003-09-29 2010-01-15 Merck Sharp & Dohme Optimized expression of hpv 45 l1 in yeast
US7901921B2 (en) 2004-10-22 2011-03-08 Oncolytics Biotech Inc. Viral purification methods
DK2134360T3 (en) 2007-03-14 2016-02-22 Takeda Vaccines Inc Purification of virus-like particle
RU2377305C1 (ru) * 2008-11-13 2009-12-27 Всеволод Иванович Киселев Мукозальная вакцина для иммунотерапии заболеваний, обусловленных вирусами папилломы человека, и способ лечения с ее использованием (варианты)
US9566323B2 (en) * 2009-06-19 2017-02-14 Eyegene Inc. Vaccine for cervical cancer
JOP20130186B1 (ar) 2012-06-22 2021-08-17 Takeda Vaccines Montana Inc تنقية الجزيئات الشبيهة بالفيروسات
CN103936840B (zh) * 2013-01-18 2019-04-09 北京康乐卫士生物技术股份有限公司 重组的人乳头瘤病毒33型l1蛋白及其用途
CN113278064B (zh) * 2021-07-20 2021-11-02 山东信得科技股份有限公司 一种用于胚毒类抗原净化处理的方法及其应用

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE122007000016I1 (de) * 1991-07-19 2007-05-24 Univ Queensland Impfstoffe gegen Papillomavirus
US5437951A (en) * 1992-09-03 1995-08-01 The United States Of America As Represented By The Department Of Health And Human Services Self-assembling recombinant papillomavirus capsid proteins
DE69434383T2 (de) * 1993-03-09 2005-11-24 The University Of Rochester Herstellung von menschlichem papillomavirus hüllprotein und virus-ähnlichen teilchen
JP3863559B2 (ja) * 1994-05-16 2006-12-27 メルク エンド カンパニー インコーポレーテッド 乳頭腫ウィルスワクチン

Also Published As

Publication number Publication date
RU2161651C2 (ru) 2001-01-10
FI972030L (fi) 1997-05-13
ATE245192T1 (de) 2003-08-15
DE69531308D1 (de) 2003-08-21
CN1173203A (zh) 1998-02-11
AR004464A1 (es) 1998-12-16
MX9703570A (es) 1997-08-30
DE69531308T2 (de) 2004-04-15
EP0789767A1 (de) 1997-08-20
KR987000420A (ko) 1998-03-30
FI972030A0 (fi) 1997-05-13
CZ145297A3 (en) 1997-10-15
PT789767E (pt) 2003-11-28
YU71195A (sh) 1999-06-15
AU4365896A (en) 1996-06-06
ES2201129T3 (es) 2004-03-16
SK59497A3 (en) 1998-03-04
WO1996015247A1 (en) 1996-05-23
HRP950557A2 (en) 1997-08-31
HUT77559A (hu) 1998-06-29
EP0789767B1 (de) 2003-07-16
UA35639C2 (uk) 2001-04-16
AU708737B2 (en) 1999-08-12
SK281878B6 (sk) 2001-08-06
FI972030A7 (fi) 1997-05-13
NZ298224A (en) 1999-05-28
BR9510520A (pt) 1998-07-14
JPH11500002A (ja) 1999-01-06

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