DK0808831T3 - Fluorerede vitamin D3-analoger - Google Patents

Fluorerede vitamin D3-analoger

Info

Publication number
DK0808831T3
DK0808831T3 DK97107848T DK97107848T DK0808831T3 DK 0808831 T3 DK0808831 T3 DK 0808831T3 DK 97107848 T DK97107848 T DK 97107848T DK 97107848 T DK97107848 T DK 97107848T DK 0808831 T3 DK0808831 T3 DK 0808831T3
Authority
DK
Denmark
Prior art keywords
analogues
fluorinated vitamin
fluorinated
vitamin
Prior art date
Application number
DK97107848T
Other languages
English (en)
Inventor
Milan Radoje Uskokovic
Bernard Michael Hennessy
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Application granted granted Critical
Publication of DK0808831T3 publication Critical patent/DK0808831T3/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C401/00Irradiation products of cholesterol or its derivatives; Vitamin D derivatives, 9,10-seco cyclopenta[a]phenanthrene or analogues obtained by chemical preparation without irradiation
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/59Compounds containing 9, 10- seco- cyclopenta[a]hydrophenanthrene ring systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/06Antipsoriatics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/08Antiseborrheics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/02Nutrients, e.g. vitamins, minerals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/02Antineoplastic agents specific for leukemia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Dermatology (AREA)
  • Hematology (AREA)
  • Oncology (AREA)
  • Diabetes (AREA)
  • Obesity (AREA)
  • Nutrition Science (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DK97107848T 1996-05-23 1997-05-14 Fluorerede vitamin D3-analoger DK0808831T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US1818796P 1996-05-23 1996-05-23

Publications (1)

Publication Number Publication Date
DK0808831T3 true DK0808831T3 (da) 2001-01-02

Family

ID=21786696

Family Applications (1)

Application Number Title Priority Date Filing Date
DK97107848T DK0808831T3 (da) 1996-05-23 1997-05-14 Fluorerede vitamin D3-analoger

Country Status (30)

Country Link
US (1) US5888994A (da)
EP (1) EP0808831B1 (da)
JP (1) JP2858571B2 (da)
KR (1) KR100237523B1 (da)
CN (1) CN1081184C (da)
AR (1) AR007240A1 (da)
AT (1) ATE195514T1 (da)
AU (1) AU720098B2 (da)
BR (1) BR9703373A (da)
CA (1) CA2204478C (da)
CO (1) CO4840512A1 (da)
CZ (1) CZ157997A3 (da)
DE (1) DE69702812T2 (da)
DK (1) DK0808831T3 (da)
ES (1) ES2150719T3 (da)
GR (1) GR3034832T3 (da)
HR (1) HRP970274A2 (da)
HU (1) HUP9700927A3 (da)
IL (1) IL120842A0 (da)
MA (1) MA24345A1 (da)
NO (1) NO971934L (da)
NZ (1) NZ314838A (da)
PL (1) PL320131A1 (da)
PT (1) PT808831E (da)
SG (1) SG50831A1 (da)
TR (1) TR199700418A3 (da)
TW (1) TW374762B (da)
UY (1) UY24563A1 (da)
YU (1) YU19997A (da)
ZA (1) ZA974334B (da)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NO971934L (no) * 1996-05-23 1997-11-24 Hoffmann La Roche Flourinerte vitamin D3 -analoger
ATE322477T1 (de) * 1997-05-16 2006-04-15 Woman & Infants Hospital 3-epi-vitamin d2 verbindungen und ihre anwendungen
AU743514B2 (en) * 1997-05-16 2002-01-24 Women & Infants Hospital Cyclic ether vitamin D3 compounds, 1alpha (OH) 3-EPI-vitamin D3 compounds and uses thereof
WO1999012894A1 (en) * 1997-09-08 1999-03-18 F. Hoffmann-La Roche Ag 1,3-dihydroxy-20,20-dialkyl-vitamin d3 analogs
WO2000051554A2 (en) * 1999-03-05 2000-09-08 Johns Hopkins University Regulating skin appearance and composition with a fluorinated vitamin d3 analog compound
US7148211B2 (en) * 2002-09-18 2006-12-12 Genzyme Corporation Formulation for lipophilic agents
CA2586679A1 (en) 2004-11-12 2006-05-18 Bioxell Spa Combined use of vitamin d derivatives and anti-proliferative agents for treating bladder cancer
ES2593047T3 (es) 2006-02-03 2016-12-05 Opko Renal, Llc Tratamiento de la insuficiencia y deficiencia de vitamina D con 25-hidroxivitamina D2 y 25-hidroxivitamina D3
ES2670029T3 (es) 2006-06-21 2018-05-29 Opko Ireland Global Holdings, Ltd. Terapia usando agente de repleción de la vitamina D y agente de reemplazo de la hormona de la vitamina D
KR20190028822A (ko) 2007-04-25 2019-03-19 사이토크로마 인코포레이티드 비타민 d 화합물과 밀랍성 담체를 포함하는 경구 조절성 방출 조성물
US11752158B2 (en) 2007-04-25 2023-09-12 Eirgen Pharma Ltd. Method of treating vitamin D insufficiency and deficiency
WO2011123476A1 (en) 2010-03-29 2011-10-06 Cytochroma Inc. Methods and compositions for reducing parathyroid levels
WO2012065050A1 (en) 2010-11-12 2012-05-18 Wisconsin Alumni Research Foundation 22-haloacetoxy-homopregnacalciferol analogs and their uses
KR101847947B1 (ko) 2013-03-15 2018-05-28 옵코 아이피 홀딩스 Ⅱ 인코포레이티드 안정화되고 변형된 비타민 d 방출 제형
US10220047B2 (en) 2014-08-07 2019-03-05 Opko Ireland Global Holdings, Ltd. Adjunctive therapy with 25-hydroxyvitamin D and articles therefor
JP7032322B2 (ja) 2016-03-28 2022-03-08 オプコ アイルランド グローバル ホールディングス リミテッド ビタミンd治療法

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5039671A (en) * 1984-12-19 1991-08-13 Hoffmann-La Roche Inc. Trifluorinated-1α,25S-dihydroxy vitamin D3 compounds
US5145846A (en) * 1988-01-20 1992-09-08 Hoffmann-La Roche Inc. Vitamin D3 analogs
US4804502A (en) * 1988-01-20 1989-02-14 Hoffmann-La Roche Inc. Vitamin D compounds
GB9007236D0 (en) * 1990-03-30 1990-05-30 Leo Pharm Prod Ltd Chemical compounds
GB9017890D0 (en) * 1990-08-15 1990-09-26 Leo Pharm Prod Ltd Chemical compounds i
US5206230A (en) * 1991-06-05 1993-04-27 Daikin Industries, Ltd. Fluorine-containing vitamin D3 analogues and pharmaceutical composition containing the same
US5210237A (en) * 1991-08-27 1993-05-11 Daikin Industries, Ltd. Vitamin d3 analogues
US5200536A (en) * 1992-02-10 1993-04-06 Daikin Industries Ltd. Fluorine-containing vitamin D3 analogues
GB9206648D0 (en) * 1992-03-26 1992-05-06 Leo Pharm Prod Ltd Chemical compounds
DE69304279T2 (de) * 1992-05-20 1997-02-20 Hoffmann La Roche Fluorierte Analoge Vitamins D3
CA2096105A1 (en) * 1992-10-07 1994-04-08 Enrico Giuseppe Baggiolini (Deceased) Vitamin d3 fluorinated analogs
TW267161B (da) * 1992-11-20 1996-01-01 Hoffmann La Roche
US5428029A (en) * 1993-11-24 1995-06-27 Hoffmann-La Roche Inc. Vitamin D3 fluorinated analogs
US5384314B1 (en) * 1994-03-11 1997-08-05 Hoffmann La Roche 1alpha-fluoro-25-hydroxy-16-ene-23-yne-cholecalciferol
NO971934L (no) * 1996-05-23 1997-11-24 Hoffmann La Roche Flourinerte vitamin D3 -analoger

Also Published As

Publication number Publication date
HU9700927D0 (en) 1997-07-28
ATE195514T1 (de) 2000-09-15
TW374762B (en) 1999-11-21
HRP970274A2 (en) 1998-04-30
KR100237523B1 (ko) 2000-01-15
MX9703776A (es) 1998-06-30
EP0808831B1 (en) 2000-08-16
CZ157997A3 (en) 1997-12-17
MA24345A1 (fr) 1998-07-01
CN1169425A (zh) 1998-01-07
CA2204478A1 (en) 1997-11-23
TR199700418A2 (xx) 1997-12-21
US5888994A (en) 1999-03-30
NO971934L (no) 1997-11-24
BR9703373A (pt) 1998-09-15
CA2204478C (en) 2006-11-21
ES2150719T3 (es) 2000-12-01
HUP9700927A2 (hu) 1998-01-28
GR3034832T3 (en) 2001-02-28
PL320131A1 (en) 1997-11-24
SG50831A1 (en) 1998-07-20
EP0808831A3 (en) 1999-02-03
DE69702812T2 (de) 2001-01-25
JP2858571B2 (ja) 1999-02-17
JPH1045712A (ja) 1998-02-17
PT808831E (pt) 2000-12-29
CO4840512A1 (es) 1999-09-27
AU2357297A (en) 1997-11-27
DE69702812D1 (de) 2000-09-21
HUP9700927A3 (en) 1999-07-28
NO971934D0 (no) 1997-04-25
YU19997A (sh) 1999-07-28
CN1081184C (zh) 2002-03-20
UY24563A1 (es) 2000-12-29
IL120842A0 (en) 1997-09-30
EP0808831A2 (en) 1997-11-26
ZA974334B (en) 1997-11-24
NZ314838A (en) 1998-01-26
KR970074763A (ko) 1997-12-10
TR199700418A3 (tr) 1997-12-21
AR007240A1 (es) 1999-10-27
AU720098B2 (en) 2000-05-25

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