DK0809493T3 - Fremgangsmåde til behandling af hyperproliferative epitel-hudsygdomme ved topisk tilførsel af hydroxylerede, aromatiske protein-tværbindingsforbindelser - Google Patents

Fremgangsmåde til behandling af hyperproliferative epitel-hudsygdomme ved topisk tilførsel af hydroxylerede, aromatiske protein-tværbindingsforbindelser

Info

Publication number
DK0809493T3
DK0809493T3 DK96905555T DK96905555T DK0809493T3 DK 0809493 T3 DK0809493 T3 DK 0809493T3 DK 96905555 T DK96905555 T DK 96905555T DK 96905555 T DK96905555 T DK 96905555T DK 0809493 T3 DK0809493 T3 DK 0809493T3
Authority
DK
Denmark
Prior art keywords
treatment
topical application
skin diseases
hyperproliferative epithelial
protein cross
Prior art date
Application number
DK96905555T
Other languages
Danish (da)
English (en)
Inventor
Stuart H Yuspa
Caroline Stanwell
Terrence R Burke Jr
Original Assignee
Us Health
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Us Health filed Critical Us Health
Application granted granted Critical
Publication of DK0809493T3 publication Critical patent/DK0809493T3/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/472—Non-condensed isoquinolines, e.g. papaverine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/216—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acids having aromatic rings, e.g. benactizyne, clofibrate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/235—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids having an aromatic ring attached to a carboxyl group
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/472—Non-condensed isoquinolines, e.g. papaverine
    • A61K31/4725—Non-condensed isoquinolines, e.g. papaverine containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Emergency Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Dermatology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DK96905555T 1995-02-17 1996-02-14 Fremgangsmåde til behandling af hyperproliferative epitel-hudsygdomme ved topisk tilførsel af hydroxylerede, aromatiske protein-tværbindingsforbindelser DK0809493T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/389,845 US5610185A (en) 1995-02-17 1995-02-17 Method for the treatment of hyperproliferative epithelial skin diseases by topical application of hydroxylated aromatic protein cross-linking compounds
PCT/US1996/002301 WO1996025159A1 (en) 1995-02-17 1996-02-14 A method for the treatment of hyperproliferative epithelial skin diseases by topical application of hydroxylated aromatic protein cross-linking compounds

Publications (1)

Publication Number Publication Date
DK0809493T3 true DK0809493T3 (da) 2002-12-23

Family

ID=23539975

Family Applications (1)

Application Number Title Priority Date Filing Date
DK96905555T DK0809493T3 (da) 1995-02-17 1996-02-14 Fremgangsmåde til behandling af hyperproliferative epitel-hudsygdomme ved topisk tilførsel af hydroxylerede, aromatiske protein-tværbindingsforbindelser

Country Status (11)

Country Link
US (1) US5610185A (de)
EP (1) EP0809493B1 (de)
JP (1) JPH11503111A (de)
AT (1) ATE223715T1 (de)
AU (1) AU698414B2 (de)
CA (1) CA2212888C (de)
DE (1) DE69623595T2 (de)
DK (1) DK0809493T3 (de)
ES (1) ES2183938T3 (de)
PT (1) PT809493E (de)
WO (1) WO1996025159A1 (de)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6943191B1 (en) 1998-02-27 2005-09-13 The United States Of America As Represented By The Department Of Health And Human Services Disubstituted lavendustin A analogs and pharmaceutical composition comprising the analogs
FR2778560B1 (fr) * 1998-05-12 2001-06-01 Oreal Utilisation de l'acide cinnamique ou d'au moins l'un de ses derives dans une composition destinee a favoriser la desquamation de la peau, et composition le comprenant
GB2370989A (en) * 2001-01-16 2002-07-17 Btg Int Ltd Piperine analogues for the treatment of skin conditions
WO2003101927A1 (en) * 2002-05-31 2003-12-11 Proteotech, Inc. Compounds, compositions and methods for the treatment of amyloid diseases and synucleinopathies such as alzheimer's disease, type 2 diabetes, and parkinson's disease
US7368593B1 (en) 2003-08-18 2008-05-06 Organics L.L.C. Method of selective esterification
ES2238924B1 (es) 2004-02-17 2006-12-01 Investread Europa, S.L. Uso del acido 2,5-dihidroxibencenosulfonico, en la fabricacion de medicamentos de aplicacion en el tratamiento de enfermedades angiodependientes.
US20070149618A1 (en) 2004-02-17 2007-06-28 Action Medicines, S.L. Methods of use for 2,5-dihydroxybenzene sulfonic acid compounds for the treatment of cancer, rosacea and psoriasis
US20080125485A1 (en) 2004-02-17 2008-05-29 Action Medicines Use of 2,5-Dihydroxybenzene Derivatives for Treating Actinic Keratosis
WO2005092322A1 (ja) * 2004-03-29 2005-10-06 Japan Health Sciences Foundation Ｒａｒ活性化を起こす天然化合物
US7351739B2 (en) * 2004-04-30 2008-04-01 Wellgen, Inc. Bioactive compounds and methods of uses thereof
FR2892923B1 (fr) * 2005-11-08 2009-01-16 Engelhard Lyon Sa Utilisatiion des derives de l'acide para-coumarique ou para- hydroxycinnamique dans des compositions cosmetiques ou dermatologiques.
US8541467B2 (en) 2006-08-16 2013-09-24 Action Medicines, S.L. Use of 2,5-dihydroxybenzene compounds and derivatives for the treatment of hematological dyscrasias and cancer of an organ
PT2056815E (pt) 2006-08-16 2013-04-03 Amderma Pharmaceuticals Llc Utilização de derivados de 2,5-dihidroxibenzeno para tratar dermatite
CN117247319A (zh) * 2023-09-08 2023-12-19 中国药科大学 一类5,6-二羟基萘甲酸酯化合物及其制备方法与用途
CN119219499B (zh) * 2024-09-02 2025-09-26 昆明医科大学 倍半萜醇咖啡酸酯类化合物及其制备方法和应用

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2492815A1 (fr) * 1980-10-23 1982-04-30 Sori Soc Rech Ind Nouveau derive d'acide cinnamoyl-cinnamique, son procede de preparation et son application en therapeutique
US4925877A (en) * 1986-02-25 1990-05-15 Zaidanhojin Biseibutsu Kagaku Kenkyukai Physiologically active erbstatin analogue compounds and compositions
FR2601670B1 (fr) * 1986-07-17 1988-10-07 Cird Nouveaux derives bicycliques aromatiques, leur procede de preparation et leur utilisation en medecine humaine et veterinaire et en cosmetique
JPH03109323A (ja) * 1989-09-22 1991-05-09 Microbial Chem Res Found 抗ガン剤
US5360815A (en) * 1993-06-23 1994-11-01 Merck Frosst Canada, Inc. Heteroaryl cinnamic acids as inhibitors of leukotriene biosynthesis
JPH0761919A (ja) * 1993-08-26 1995-03-07 Kao Corp 美白剤

Also Published As

Publication number Publication date
AU698414B2 (en) 1998-10-29
CA2212888A1 (en) 1996-08-22
DE69623595D1 (de) 2002-10-17
AU4928696A (en) 1996-09-04
DE69623595T2 (de) 2003-05-22
JPH11503111A (ja) 1999-03-23
CA2212888C (en) 2006-10-17
ATE223715T1 (de) 2002-09-15
US5610185A (en) 1997-03-11
EP0809493A1 (de) 1997-12-03
ES2183938T3 (es) 2003-04-01
WO1996025159A1 (en) 1996-08-22
PT809493E (pt) 2003-01-31
EP0809493B1 (de) 2002-09-11

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