DK0813411T3 - Anvendelse af vincopetinderivater til hæmning af dannelse eller afsondring af amyloid -protein - Google Patents

Anvendelse af vincopetinderivater til hæmning af dannelse eller afsondring af amyloid -protein

Info

Publication number: DK0813411T3
Authority: DK; Denmark
Prior art keywords: pct; optionally substituted; secretion; date; vincopetine
Prior art date: 1995-02-15

Application number

DK96901960T

Other languages

Danish (da)

English (en)

Inventor

Mitsuru Kakihana

Takuo Kosaka

Akinobu Nagaoka

Giichi Goto

Original Assignee

Takeda Chemical Industries Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1995-02-15

Filing date

1996-02-08

Publication date

2002-05-13

1996-02-08 Application filed by Takeda Chemical Industries Ltd filed Critical Takeda Chemical Industries Ltd

2002-05-13 Application granted granted Critical

2002-05-13 Publication of DK0813411T3 publication Critical patent/DK0813411T3/da

Links

230000028327 secretion Effects 0.000 title abstract 2
102000009091 Amyloidogenic Proteins Human genes 0.000 title 1
108010048112 Amyloidogenic Proteins Proteins 0.000 title 1
230000014616 translation Effects 0.000 title 1
102000013455 Amyloid beta-Peptides Human genes 0.000 abstract 1
108010090849 Amyloid beta-Peptides Proteins 0.000 abstract 1
150000001875 compounds Chemical class 0.000 abstract 1
239000003085 diluting agent Substances 0.000 abstract 1
239000003937 drug carrier Substances 0.000 abstract 1
125000000623 heterocyclic group Chemical group 0.000 abstract 1
125000001183 hydrocarbyl group Chemical group 0.000 abstract 1
125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 1
230000002401 inhibitory effect Effects 0.000 abstract 1
229910052757 nitrogen Inorganic materials 0.000 abstract 1
125000004433 nitrogen atom Chemical group N* 0.000 abstract 1
QJGQUHMNIGDVPM-UHFFFAOYSA-N nitrogen group Chemical group [N] QJGQUHMNIGDVPM-UHFFFAOYSA-N 0.000 abstract 1
239000008194 pharmaceutical composition Substances 0.000 abstract 1
239000000546 pharmaceutical excipient Substances 0.000 abstract 1
125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1
125000000547 substituted alkyl group Chemical group 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/475—Quinolines; Isoquinolines having an indole ring, e.g. yohimbine, reserpine, strychnine, vinblastine

Landscapes

Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
Pharmacology & Pharmacy (AREA)
Epidemiology (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical & Material Sciences (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Veterinary Medicine (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Plural Heterocyclic Compounds (AREA)

DK96901960T 1995-02-15 1996-02-08 Anvendelse af vincopetinderivater til hæmning af dannelse eller afsondring af amyloid -protein DK0813411T3 (da)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
JP2668795		1995-02-15
PCT/JP1996/000265 WO1996025161A1 (en)	1995-02-15	1996-02-08	Use of vinpocetine derivatives for inhibiting production or secretion of amyloid beta protein

Publications (1)

Publication Number	Publication Date
DK0813411T3 true DK0813411T3 (da)	2002-05-13

Family

ID=12200316

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK96901960T DK0813411T3 (da)	1995-02-15	1996-02-08	Anvendelse af vincopetinderivater til hæmning af dannelse eller afsondring af amyloid -protein

Country Status (11)

Country	Link
US (1)	US5965568A (de)
EP (1)	EP0813411B1 (de)
AT (1)	ATE212227T1 (de)
AU (1)	AU4632996A (de)
CA (1)	CA2213094A1 (de)
DE (1)	DE69618765T2 (de)
DK (1)	DK0813411T3 (de)
ES (1)	ES2171646T3 (de)
HU (1)	HUP9801155A3 (de)
PT (1)	PT813411E (de)
WO (1)	WO1996025161A1 (de)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
WO2000024392A1 (en) *	1998-10-26	2000-05-04	Sumitomo Pharmaceuticals Company, Limited	β-AMYLOID FORMATION INHIBITORS
EP2316531A1 (de) *	2000-08-10	2011-05-04	Cold Spring Harbor Laboratory	Gesteigertes kognitives Training
US8153646B2 (en) *	2000-08-10	2012-04-10	Dart Neuroscience (Cayman) Ltd.	Phosphodiesterase 4 inhibitors for cognitive and motor rehabilitation
AU2003289889A1 (en) *	2002-11-22	2004-06-18	Novartis Ag	Methods for the treatment of alzheimers disease and compositions therefore
RU2376990C2 (ru) *	2003-10-28	2009-12-27	Универсидад Насиональ Аутонома Де Мексико	Применение винпоцетина для предупреждения осложнений, в частности осложнений, связанных со слухом, которые сопутствуют эпилепсии и ее лечению
EP1679059A4 (de) *	2003-10-28	2009-11-04	Univ Mexico Nacional Autonoma	Verwendung von vinpocetin zur vermeidung von komplikationen, insbesondere im zusammenhang mit dem gehör, die bei epilepsie auftreten, und ihre behandlung
GB0329498D0 (en) *	2003-12-19	2004-01-28	Novartis Ag	Organic compounds
CZ2006628A3 (cs) *	2004-03-12	2007-01-24	Egis Gyogyszergyár Nyrt.	Kombinovaná farmaceutická kompozice pro inhibici poklesu kognitivních funkcí
JP5160764B2 (ja)	2006-10-13	2013-03-13	全薬工業株式会社	特定の構造の複素環化合物を含む抗鬱剤、脳保護剤、アミロイドβ沈着抑制剤または老化抑制剤
KR101095026B1 (ko) *	2009-01-23	2011-12-20	한국과학기술연구원	비스(스티릴)피리미딘 및 비스(스티릴)벤젠 유도체, 이의 약학적으로 허용 가능한 염, 이의 제조방법 및 이를 유효성분으로 함유하는 베타아밀로이드 집적 관련 질환의 예방 또는 치료용 약학적 조성물
WO2010103539A2 (en)	2009-03-09	2010-09-16	Dinesh Shantilal Patel	Sustained release oral formulation of vinpocetine
CN102875547B (zh) *	2011-07-15	2015-05-27	海南灵康制药有限公司	一种长春西汀化合物及其制法

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4035370A (en) *	1971-11-03	1977-07-12	Richter Gedeon Vegyeszeti Gyar Rt.	Alkaloid esters
HU181941B (en) *	1979-11-23	1983-11-28	Richter Gedeon Vegyeszet	Process for producing apovincaminic acid ester derivatives
HU201674B (en) *	1987-08-26	1990-12-28	Richter Gedeon Vegyeszet	Process for producing pharmaceutical composition suitable for curing autoimmune-type leukoencephalomyelitic diseases e.g. sclerosis multiplex
JPH02167279A (ja) *	1988-09-30	1990-06-27	Taisho Pharmaceut Co Ltd	アポビンカミン酸誘導体
JPH02152979A (ja) *	1988-12-06	1990-06-12	Taisho Pharmaceut Co Ltd	アポビンカミン酸誘導体
JPH02204488A (ja) *	1989-02-03	1990-08-14	Taisho Pharmaceut Co Ltd	エブルナメニン誘導体
JP3053913B2 (ja) *	1991-07-15	2000-06-19	帝三製薬株式会社	ビンポセチン類含有貼付剤
US5296478A (en) *	1992-10-07	1994-03-22	The Dupont Merck Pharmaceutical Co.	1-substituted oxindoles as cognition enhancers
ATE239797T1 (de) *	1993-01-25	2003-05-15	Takeda Chemical Industries Ltd	Antikörper gegen beta-amyloid oder derivative davon und seine verwendung

1996
- 1996-02-08 AT AT96901960T patent/ATE212227T1/de not_active IP Right Cessation
- 1996-02-08 DK DK96901960T patent/DK0813411T3/da active
- 1996-02-08 WO PCT/JP1996/000265 patent/WO1996025161A1/en not_active Ceased
- 1996-02-08 ES ES96901960T patent/ES2171646T3/es not_active Expired - Lifetime
- 1996-02-08 PT PT96901960T patent/PT813411E/pt unknown
- 1996-02-08 AU AU46329/96A patent/AU4632996A/en not_active Abandoned
- 1996-02-08 HU HU9801155A patent/HUP9801155A3/hu unknown
- 1996-02-08 EP EP96901960A patent/EP0813411B1/de not_active Expired - Lifetime
- 1996-02-08 CA CA002213094A patent/CA2213094A1/en not_active Abandoned
- 1996-02-08 US US08/646,354 patent/US5965568A/en not_active Expired - Fee Related
- 1996-02-08 DE DE69618765T patent/DE69618765T2/de not_active Expired - Fee Related

Also Published As

Publication number	Publication date
US5965568A (en)	1999-10-12
HUP9801155A2 (hu)	1998-09-28
AU4632996A (en)	1996-09-04
PT813411E (pt)	2002-07-31
ES2171646T3 (es)	2002-09-16
HUP9801155A3 (en)	1999-03-01
DE69618765D1 (de)	2002-03-14
EP0813411A1 (de)	1997-12-29
WO1996025161A1 (en)	1996-08-22
DE69618765T2 (de)	2002-10-17
EP0813411B1 (de)	2002-01-23
ATE212227T1 (de)	2002-02-15
CA2213094A1 (en)	1996-08-22

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