DK0819108T3 - Fremgangsmåde til fremstilling af galanthaminderivater ved asymmetrisk reduktion - Google Patents

Fremgangsmåde til fremstilling af galanthaminderivater ved asymmetrisk reduktion

Info

Publication number: DK0819108T3
Authority: DK; Denmark
Prior art keywords: pct; preparation; asymmetric reduction; sec; alkyl
Prior art date: 1995-04-06

Application number

DK96909250T

Other languages

Danish (da)

English (en)

Inventor

Ulrich Conrad Dyer

Jane Marie Paul

Raymond Mccague

Original Assignee

Janssen Pharmaceutica Nv

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1995-04-06

Filing date

1996-04-04

Publication date

2001-11-26

1995-04-06 Priority claimed from GBGB9507100.7A external-priority patent/GB9507100D0/en

1996-01-22 Priority claimed from GBGB9601227.3A external-priority patent/GB9601227D0/en

1996-04-04 Application filed by Janssen Pharmaceutica Nv filed Critical Janssen Pharmaceutica Nv

2001-11-26 Application granted granted Critical

2001-11-26 Publication of DK0819108T3 publication Critical patent/DK0819108T3/da

Links

ASUTZQLVASHGKV-JDFRZJQESA-N galanthamine Chemical class O1C(=C23)C(OC)=CC=C2CN(C)CC[C@]23[C@@H]1C[C@@H](O)C=C2 ASUTZQLVASHGKV-JDFRZJQESA-N 0.000 title 1
125000003837 (C1-C20) alkyl group Chemical group 0.000 abstract 2
IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical compound N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 abstract 2
150000001875 compounds Chemical class 0.000 abstract 2
125000001424 substituent group Chemical group 0.000 abstract 2
125000002252 acyl group Chemical group 0.000 abstract 1
125000004453 alkoxycarbonyl group Chemical group 0.000 abstract 1
239000003638 chemical reducing agent Substances 0.000 abstract 1
238000004519 manufacturing process Methods 0.000 abstract 1
229910052757 nitrogen Inorganic materials 0.000 abstract 1
239000002243 precursor Substances 0.000 abstract 1
125000006239 protecting group Chemical group 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/10—Spiro-condensed systems
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Saccharide Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)

DK96909250T 1995-04-06 1996-04-04 Fremgangsmåde til fremstilling af galanthaminderivater ved asymmetrisk reduktion DK0819108T3 (da)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
GBGB9507100.7A GB9507100D0 (en)	1995-04-06	1995-04-06	Asymmetric reduction and products thereof
GBGB9601227.3A GB9601227D0 (en)	1996-01-22	1996-01-22	Reduction
PCT/GB1996/000843 WO1996031453A1 (en)	1995-04-06	1996-04-04	Process for preparing galanthamine derivatives by asymmetric reduction

Publications (1)

Publication Number	Publication Date
DK0819108T3 true DK0819108T3 (da)	2001-11-26

Family

ID=26306827

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK96909250T DK0819108T3 (da)	1995-04-06	1996-04-04	Fremgangsmåde til fremstilling af galanthaminderivater ved asymmetrisk reduktion

Country Status (12)

Country	Link
US (1)	US6018043A (de)
EP (1)	EP0819108B1 (de)
AT (1)	ATE204840T1 (de)
AU (1)	AU709080B2 (de)
CA (1)	CA2215518C (de)
CY (1)	CY2257B1 (de)
DE (1)	DE69614841T2 (de)
DK (1)	DK0819108T3 (de)
ES (1)	ES2162042T3 (de)
PT (1)	PT819108E (de)
TW (1)	TW448177B (de)
WO (1)	WO1996031453A1 (de)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB9506843D0 (en) *	1995-04-03	1995-05-24	Chiroscience Ltd	Oxidative process and products thereof
CA2540248C (en) *	2003-09-26	2010-12-07	Scinopharm Taiwan, Ltd.	Resolution of a narwedine amide derivative
WO2005065662A1 (en) *	2003-12-31	2005-07-21	Actavis Group Hf	Solid dosage formulations of galantamine
CA2551946A1 (en) *	2003-12-31	2005-07-21	Actavis Group Hf	Immediate, controlled and sustained release formulations of galantamine
WO2006124585A2 (en) *	2005-05-13	2006-11-23	Alza Corporation	Multilayer drug system for the delivery of galantamine
EP1937226A2 (de) *	2005-09-23	2008-07-02	Alza Corporation	Transdermales galantaminzufuhrsystem
CN100364995C (zh) *	2006-01-12	2008-01-30	兰州大学	加兰它敏制备方法
EP2009015B1 (de)	2007-06-18	2012-01-11	Aurobindo Pharma Limited	Herstellungsprozess für Galantaminhydrobromid
AT507039A1 (de) *	2008-06-26	2010-01-15	Sanochemia Pharmazeutika Ag	Verfahren zum herstellen von hochreinen benzazepinderivaten
CN102180886B (zh) *	2011-03-05	2015-01-21	兰州大学	加兰他敏不对称催化合成方法

1996
- 1996-04-04 AU AU52819/96A patent/AU709080B2/en not_active Expired
- 1996-04-04 EP EP96909250A patent/EP0819108B1/de not_active Expired - Lifetime
- 1996-04-04 AT AT96909250T patent/ATE204840T1/de active
- 1996-04-04 DK DK96909250T patent/DK0819108T3/da active
- 1996-04-04 ES ES96909250T patent/ES2162042T3/es not_active Expired - Lifetime
- 1996-04-04 WO PCT/GB1996/000843 patent/WO1996031453A1/en not_active Ceased
- 1996-04-04 PT PT96909250T patent/PT819108E/pt unknown
- 1996-04-04 US US08/930,211 patent/US6018043A/en not_active Expired - Lifetime
- 1996-04-04 DE DE69614841T patent/DE69614841T2/de not_active Expired - Lifetime
- 1996-04-04 CA CA002215518A patent/CA2215518C/en not_active Expired - Lifetime
- 1996-04-19 TW TW085104664A patent/TW448177B/zh not_active IP Right Cessation
2002
- 2002-01-04 CY CY0200005A patent/CY2257B1/xx unknown

Also Published As

Publication number	Publication date
AU5281996A (en)	1996-10-23
WO1996031453A1 (en)	1996-10-10
ES2162042T3 (es)	2001-12-16
EP0819108B1 (de)	2001-08-29
CA2215518A1 (en)	1996-10-10
DE69614841T2 (de)	2002-04-11
ATE204840T1 (de)	2001-09-15
PT819108E (pt)	2002-02-28
US6018043A (en)	2000-01-25
TW448177B (en)	2001-08-01
AU709080B2 (en)	1999-08-19
EP0819108A1 (de)	1998-01-21
CA2215518C (en)	2006-11-28
CY2257B1 (en)	2003-07-04
DE69614841D1 (de)	2001-10-04

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