DK0835251T3 - Fremgangsmåde til fremstilling af liponsyre - Google Patents
Fremgangsmåde til fremstilling af liponsyreInfo
- Publication number
- DK0835251T3 DK0835251T3 DK96919924T DK96919924T DK0835251T3 DK 0835251 T3 DK0835251 T3 DK 0835251T3 DK 96919924 T DK96919924 T DK 96919924T DK 96919924 T DK96919924 T DK 96919924T DK 0835251 T3 DK0835251 T3 DK 0835251T3
- Authority
- DK
- Denmark
- Prior art keywords
- pct
- preparation
- date
- lipoic acid
- sec
- Prior art date
Links
- 235000019136 lipoic acid Nutrition 0.000 title abstract 2
- 238000000034 method Methods 0.000 title abstract 2
- 229960002663 thioctic acid Drugs 0.000 title abstract 2
- AGBQKNBQESQNJD-UHFFFAOYSA-M lipoate Chemical compound [O-]C(=O)CCCCC1CCSS1 AGBQKNBQESQNJD-UHFFFAOYSA-M 0.000 title 1
- AGBQKNBQESQNJD-SSDOTTSWSA-N (R)-lipoic acid Chemical compound OC(=O)CCCC[C@@H]1CCSS1 AGBQKNBQESQNJD-SSDOTTSWSA-N 0.000 abstract 1
- -1 2-substituted cyclohexanone Chemical class 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- AGBQKNBQESQNJD-UHFFFAOYSA-N alpha-Lipoic acid Natural products OC(=O)CCCCC1CCSS1 AGBQKNBQESQNJD-UHFFFAOYSA-N 0.000 abstract 1
- 150000002596 lactones Chemical class 0.000 abstract 1
- 238000007254 oxidation reaction Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D339/00—Heterocyclic compounds containing rings having two sulfur atoms as the only ring hetero atoms
- C07D339/02—Five-membered rings
- C07D339/04—Five-membered rings having the hetero atoms in positions 1 and 2, e.g. lipoic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P39/00—General protective or antinoxious agents
- A61P39/02—Antidotes
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Diabetes (AREA)
- Public Health (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Endocrinology (AREA)
- Obesity (AREA)
- Emergency Medicine (AREA)
- Hematology (AREA)
- Toxicology (AREA)
- Gastroenterology & Hepatology (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Heterocyclic Compounds Containing Sulfur Atoms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Pyrane Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB9510858.5A GB9510858D0 (en) | 1995-05-30 | 1995-05-30 | Process for preparing lipoic acid |
| PCT/GB1996/001278 WO1996038437A1 (en) | 1995-05-30 | 1996-05-30 | Process for the production of lipoic acid |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK0835251T3 true DK0835251T3 (da) | 2000-06-26 |
Family
ID=10775210
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK96919924T DK0835251T3 (da) | 1995-05-30 | 1996-05-30 | Fremgangsmåde til fremstilling af liponsyre |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US6140512A (da) |
| EP (1) | EP0835251B1 (da) |
| JP (1) | JP3856830B2 (da) |
| AT (1) | ATE189219T1 (da) |
| AU (1) | AU5828896A (da) |
| DE (1) | DE69606411T2 (da) |
| DK (1) | DK0835251T3 (da) |
| ES (1) | ES2143206T3 (da) |
| GB (1) | GB9510858D0 (da) |
| GR (1) | GR3033198T3 (da) |
| PT (1) | PT835251E (da) |
| WO (1) | WO1996038437A1 (da) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6562869B1 (en) | 1999-09-23 | 2003-05-13 | Juvenon, Inc. | Nutritional supplement for increased energy and stamina |
| AU7828200A (en) | 1999-09-23 | 2001-04-24 | Juvenon Corporation | Nutritional supplement for increased energy and stamina |
| CA2418155A1 (en) * | 2000-07-18 | 2002-01-24 | National Research Council Of Canada | Cloning, sequencing and expression of a comamonas cyclopentanone 1,2-monooxygenase-encoding gene in escherichia coli |
| DE10038147A1 (de) * | 2000-08-04 | 2002-02-14 | Sued Chemie Ag | Propfpolymere oder -copolymere |
| IT1319194B1 (it) | 2000-10-10 | 2003-09-26 | Laboratorio Chimico Int Spa | Processo per la produzione dell'acido tiottico racemo. |
| IT1319196B1 (it) * | 2000-10-10 | 2003-09-26 | Laboratorio Chimico Int Spa | Sintesi dell'acido r(+)alfa-lipoico. |
| US20040137551A1 (en) * | 2003-01-13 | 2004-07-15 | Markovic Nenad S. | Cervical acid phosphatase - papanicolaou (CAP-PAP) test kit, method and accesories, processes for producing and using the same |
| US20090078581A1 (en) * | 2007-09-24 | 2009-03-26 | Applied Intellectual Capital | Configurations and Methods of Reduction of Lipoic Acid |
| CN115772155B (zh) * | 2021-09-07 | 2023-10-24 | 山东新时代药业有限公司 | 一种α-硫辛酸中间体的制备方法 |
| CN116925035B (zh) * | 2023-07-27 | 2026-03-06 | 风火轮(上海)生物科技有限公司 | 一种硫辛酸的纯化方法 |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE4229914A1 (de) * | 1992-09-08 | 1994-03-10 | Basf Ag | Verbessertes Verfahren zur Herstellung von R/S-Ï-Liponsäure oder R/S-â-Liponsäure |
| ES2114984T3 (es) * | 1992-09-08 | 1998-06-16 | Basf Ag | Procedimiento mejorado para la obtencion de acido r/s-gamma-lipoico o acido r/s-alfa-lipoico. |
-
1995
- 1995-05-30 GB GBGB9510858.5A patent/GB9510858D0/en active Pending
-
1996
- 1996-05-30 EP EP96919924A patent/EP0835251B1/en not_active Expired - Lifetime
- 1996-05-30 WO PCT/GB1996/001278 patent/WO1996038437A1/en not_active Ceased
- 1996-05-30 JP JP53628996A patent/JP3856830B2/ja not_active Expired - Fee Related
- 1996-05-30 US US08/952,698 patent/US6140512A/en not_active Expired - Fee Related
- 1996-05-30 DE DE69606411T patent/DE69606411T2/de not_active Expired - Fee Related
- 1996-05-30 AT AT96919924T patent/ATE189219T1/de not_active IP Right Cessation
- 1996-05-30 ES ES96919924T patent/ES2143206T3/es not_active Expired - Lifetime
- 1996-05-30 PT PT96919924T patent/PT835251E/pt unknown
- 1996-05-30 AU AU58288/96A patent/AU5828896A/en not_active Abandoned
- 1996-05-30 DK DK96919924T patent/DK0835251T3/da active
-
2000
- 2000-04-12 GR GR20000400892T patent/GR3033198T3/el not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| JPH11506443A (ja) | 1999-06-08 |
| GR3033198T3 (en) | 2000-08-31 |
| ES2143206T3 (es) | 2000-05-01 |
| WO1996038437A1 (en) | 1996-12-05 |
| ATE189219T1 (de) | 2000-02-15 |
| EP0835251A1 (en) | 1998-04-15 |
| DE69606411T2 (de) | 2000-06-21 |
| AU5828896A (en) | 1996-12-18 |
| EP0835251B1 (en) | 2000-01-26 |
| JP3856830B2 (ja) | 2006-12-13 |
| PT835251E (pt) | 2000-06-30 |
| GB9510858D0 (en) | 1995-07-26 |
| US6140512A (en) | 2000-10-31 |
| DE69606411D1 (de) | 2000-03-02 |
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