DK0842143T3 - 2-(4-substituerede)-benzylamino-2-methyl-propanamid derivater - Google Patents
2-(4-substituerede)-benzylamino-2-methyl-propanamid derivaterInfo
- Publication number
- DK0842143T3 DK0842143T3 DK96924888T DK96924888T DK0842143T3 DK 0842143 T3 DK0842143 T3 DK 0842143T3 DK 96924888 T DK96924888 T DK 96924888T DK 96924888 T DK96924888 T DK 96924888T DK 0842143 T3 DK0842143 T3 DK 0842143T3
- Authority
- DK
- Denmark
- Prior art keywords
- benzylamino
- substituted
- methyl
- propanamide derivatives
- propanamide
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
- C07C237/02—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton
- C07C237/04—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being acyclic and saturated
- C07C237/06—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being acyclic and saturated having the nitrogen atoms of the carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C321/00—Thiols, sulfides, hydropolysulfides or polysulfides
- C07C321/24—Thiols, sulfides, hydropolysulfides, or polysulfides having thio groups bound to carbon atoms of six-membered aromatic rings
- C07C321/28—Sulfides, hydropolysulfides, or polysulfides having thio groups bound to carbon atoms of six-membered aromatic rings
- C07C321/30—Sulfides having the sulfur atom of at least one thio group bound to two carbon atoms of six-membered aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
- C07C323/23—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton
- C07C323/31—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton having the sulfur atom of at least one of the thio groups bound to a carbon atom of a six-membered aromatic ring of the carbon skeleton
- C07C323/33—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton having the sulfur atom of at least one of the thio groups bound to a carbon atom of a six-membered aromatic ring of the carbon skeleton having at least one of the nitrogen atoms bound to a carbon atom of the same non-condensed six-membered aromatic ring
- C07C323/35—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton having the sulfur atom of at least one of the thio groups bound to a carbon atom of a six-membered aromatic ring of the carbon skeleton having at least one of the nitrogen atoms bound to a carbon atom of the same non-condensed six-membered aromatic ring the thio group being a sulfide group
- C07C323/36—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton having the sulfur atom of at least one of the thio groups bound to a carbon atom of a six-membered aromatic ring of the carbon skeleton having at least one of the nitrogen atoms bound to a carbon atom of the same non-condensed six-membered aromatic ring the thio group being a sulfide group the sulfur atom of the sulfide group being further bound to an acyclic carbon atom
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- General Health & Medical Sciences (AREA)
- Neurosurgery (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pain & Pain Management (AREA)
- Psychiatry (AREA)
- Psychology (AREA)
- Anesthesiology (AREA)
- Hospice & Palliative Care (AREA)
- Epidemiology (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB9515412.6A GB9515412D0 (en) | 1995-07-27 | 1995-07-27 | 2-(4-substituted)-benzylamino-2-methyl-propanamide derivatives |
| PCT/EP1996/002961 WO1997005102A1 (en) | 1995-07-27 | 1996-07-05 | 2-(4-substituted)-benzylamino-2-methyl-propanamide derivatives |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DK0842143T3 true DK0842143T3 (da) | 2001-07-23 |
| DK0842143T5 DK0842143T5 (da) | 2009-06-02 |
Family
ID=10778352
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK96924888T DK0842143T5 (da) | 1995-07-27 | 1996-07-05 | 2-(4-substituerede)-benzylamino-2-methyl-propanamid derivater |
Country Status (27)
| Country | Link |
|---|---|
| US (1) | US5945454A (da) |
| EP (1) | EP0842143B3 (da) |
| JP (1) | JP4040089B2 (da) |
| KR (1) | KR100412747B1 (da) |
| CN (1) | CN1085659C (da) |
| AR (1) | AR003469A1 (da) |
| AT (1) | ATE202078T1 (da) |
| AU (1) | AU711309B2 (da) |
| BR (1) | BR9609849B1 (da) |
| CA (1) | CA2226894C (da) |
| DE (2) | DE69613377T4 (da) |
| DK (1) | DK0842143T5 (da) |
| EA (1) | EA001322B1 (da) |
| ES (1) | ES2159749T7 (da) |
| GB (1) | GB9515412D0 (da) |
| GR (1) | GR3036559T3 (da) |
| HU (1) | HU227806B1 (da) |
| IL (1) | IL122705A (da) |
| MX (1) | MX9800718A (da) |
| NO (1) | NO324273B1 (da) |
| NZ (1) | NZ313185A (da) |
| PL (1) | PL184302B1 (da) |
| PT (1) | PT842143E (da) |
| SI (1) | SI0842143T1 (da) |
| UA (1) | UA44331C2 (da) |
| WO (1) | WO1997005102A1 (da) |
| ZA (1) | ZA965998B (da) |
Families Citing this family (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TW544448B (en) * | 1997-07-11 | 2003-08-01 | Novartis Ag | Pyridine derivatives |
| EP1032377B1 (en) | 1997-11-21 | 2010-11-17 | Purdue Neuroscience Company | Substituted 2-aminoacetamides and the use thereof |
| GB9727523D0 (en) | 1997-12-31 | 1998-02-25 | Pharmacia & Upjohn Spa | Alpha-aminoamide derivatives useful as analgesic agents |
| US6281211B1 (en) | 1999-02-04 | 2001-08-28 | Euro-Celtique S.A. | Substituted semicarbazides and the use thereof |
| DK1169060T3 (da) | 1999-04-09 | 2006-01-16 | Euro Celtique Sa | Natriumkanalblokkerpræparater og anvendelse deraf |
| AU4961001A (en) * | 2000-03-31 | 2001-10-15 | Cocensys Inc | Aminopyridines and their use as anticonvulsants and sodium channel blockers |
| DK1423168T3 (da) | 2001-09-03 | 2006-05-15 | Newron Pharm Spa | Farmaceutisk præparat omfattende gabapentin eller en analog deraf og et alfa-aminoamid og dets analgetiske anvendelse |
| US6667327B2 (en) | 2002-02-04 | 2003-12-23 | Hoffmann-La Roche Inc. | Pyridine amido derivatives |
| EP1438956A1 (en) * | 2003-01-16 | 2004-07-21 | Newron Pharmaceuticals S.p.A. | Alpha-aminoamide derivatives useful as antimigraine agents |
| AR044007A1 (es) * | 2003-04-11 | 2005-08-24 | Newron Pharmaceuticals Inc | Metodos para el tratamiento de la enfermedad de parkinson |
| EP1524267A1 (en) * | 2003-10-15 | 2005-04-20 | Newron Pharmaceuticals S.p.A. | Substituted benzylaminoalkylene heterocycles |
| AU2004283452A1 (en) | 2003-10-23 | 2005-05-06 | F. Hoffmann-La Roche Ag | Benzazepine derivatives as MAO-B inhibitors |
| EP1557166A1 (en) * | 2004-01-21 | 2005-07-27 | Newron Pharmaceuticals S.p.A. | Alpha-aminoamide derivatives useful in the treatment of lower urinary tract disorders |
| EP1588704A1 (en) | 2004-04-22 | 2005-10-26 | Newron Pharmaceuticals S.p.A. | Alpha-aminoamide derivatives useful in the treatment of restless legs syndrome and addictive disorders |
| DK1809271T5 (da) * | 2004-09-10 | 2010-12-06 | Newron Pharm Spa | Anvendelse af (R)-(halogenbenzyloxy)benzylaminopropanamider som natrium- og/eller calciumkanalselektive modulatorer |
| RU2008120619A (ru) * | 2005-10-26 | 2009-12-10 | БЕРИНГЕР ИНГЕЛЬХАЙМ ИНТЕРНАЦИОНАЛЬ ГмбХ (DE) | (гетеро)арилы, обладающие антагонистической активностью по отношению к меланинконцентрирующему гормону |
| EP1963280B1 (en) | 2005-12-22 | 2015-10-28 | Newron Pharmaceuticals S.p.A. | 2-phenylethylamino derivatives as calcium and/or sodium channel modulators |
| EP1870097A1 (en) * | 2006-06-15 | 2007-12-26 | Newron Pharmaceuticals S.p.A. | Alpha-aminoamide derivatives useful in the treatment of cognitive disorders |
| AU2007278837A1 (en) * | 2006-07-28 | 2008-01-31 | Alcon Research, Ltd. | Monoamine oxidase inhibitors useful for treating disorders of the outer retina |
| CA2689561C (en) | 2007-06-15 | 2015-11-17 | Newron Pharmaceuticals S.P.A. | Substituted 2- [2- (phenyl) ethylamino] alkaneamide derivatives and their use as sodium and/or calcium channel modulators |
| SI2563355T1 (sl) * | 2010-04-27 | 2016-10-28 | Newron Pharmaceuticals S.P.A. | Postopek za izdelavo metansulfonatnih soli ralfinamida ali njihovih R-enantiomerov |
| CN107709314A (zh) | 2015-06-11 | 2018-02-16 | 巴斯利尔药物国际股份公司 | 外排泵抑制剂及其治疗性用途 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IL94466A (en) * | 1989-05-25 | 1995-01-24 | Erba Carlo Spa | Pharmaceutical preparations containing the history of A-amino carboxamide N-phenylalkyl are converted into such new compounds and their preparation |
| GB9306886D0 (en) * | 1993-04-01 | 1993-05-26 | Erba Carlo Spa | Substituted (arylakoxybenzyl) aminopropanamide derivatives and process for their preparation |
| GB9306899D0 (en) * | 1993-04-01 | 1993-05-26 | Erba Carlo Spa | Substituted (arylalkylaminobenzyl) aminopropionamide derivatives and process for their preparation |
-
1995
- 1995-07-27 GB GBGB9515412.6A patent/GB9515412D0/en active Pending
-
1996
- 1996-07-05 NZ NZ313185A patent/NZ313185A/xx not_active IP Right Cessation
- 1996-07-05 WO PCT/EP1996/002961 patent/WO1997005102A1/en not_active Ceased
- 1996-07-05 UA UA98021015A patent/UA44331C2/uk unknown
- 1996-07-05 DE DE69613377T patent/DE69613377T4/de not_active Expired - Lifetime
- 1996-07-05 AU AU64187/96A patent/AU711309B2/en not_active Expired
- 1996-07-05 CN CN96195901A patent/CN1085659C/zh not_active Expired - Lifetime
- 1996-07-05 AT AT96924888T patent/ATE202078T1/de active
- 1996-07-05 US US08/981,492 patent/US5945454A/en not_active Expired - Lifetime
- 1996-07-05 CA CA002226894A patent/CA2226894C/en not_active Expired - Lifetime
- 1996-07-05 JP JP50714797A patent/JP4040089B2/ja not_active Expired - Lifetime
- 1996-07-05 BR BRPI9609849-0A patent/BR9609849B1/pt not_active IP Right Cessation
- 1996-07-05 PT PT96924888T patent/PT842143E/pt unknown
- 1996-07-05 KR KR10-1998-0700503A patent/KR100412747B1/ko not_active Expired - Lifetime
- 1996-07-05 HU HU9900351A patent/HU227806B1/hu unknown
- 1996-07-05 EP EP96924888A patent/EP0842143B3/en not_active Expired - Lifetime
- 1996-07-05 ES ES96924888T patent/ES2159749T7/es active Active
- 1996-07-05 MX MX9800718A patent/MX9800718A/es unknown
- 1996-07-05 PL PL96324639A patent/PL184302B1/pl unknown
- 1996-07-05 IL IL12270596A patent/IL122705A/xx not_active IP Right Cessation
- 1996-07-05 SI SI9630307T patent/SI0842143T1/xx unknown
- 1996-07-05 DE DE69613377A patent/DE69613377D1/de not_active Expired - Lifetime
- 1996-07-05 DK DK96924888T patent/DK0842143T5/da active
- 1996-07-05 EA EA199800170A patent/EA001322B1/ru not_active IP Right Cessation
- 1996-07-15 ZA ZA965998A patent/ZA965998B/xx unknown
- 1996-07-26 AR ARP960103752A patent/AR003469A1/es active IP Right Grant
-
1998
- 1998-01-22 NO NO19980290A patent/NO324273B1/no not_active IP Right Cessation
-
2001
- 2001-09-06 GR GR20010401413T patent/GR3036559T3/el unknown
Also Published As
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