DK0845982T3 - Anvendelse af lipider som hjælpemidler ved fremstilling af faste lægemiddelformer ved smelteekstruderingsfremgangsmåden - Google Patents

Anvendelse af lipider som hjælpemidler ved fremstilling af faste lægemiddelformer ved smelteekstruderingsfremgangsmåden

Info

Publication number
DK0845982T3
DK0845982T3 DK96929292T DK96929292T DK0845982T3 DK 0845982 T3 DK0845982 T3 DK 0845982T3 DK 96929292 T DK96929292 T DK 96929292T DK 96929292 T DK96929292 T DK 96929292T DK 0845982 T3 DK0845982 T3 DK 0845982T3
Authority
DK
Denmark
Prior art keywords
adjuvants
lipids
preparation
extrusion process
melt extrusion
Prior art date
Application number
DK96929292T
Other languages
Danish (da)
English (en)
Inventor
Joerg Rosenberg
Joerg Breitenbach
Original Assignee
Basf Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Basf Ag filed Critical Basf Ag
Application granted granted Critical
Publication of DK0845982T3 publication Critical patent/DK0845982T3/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2095—Tabletting processes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Plant Substances (AREA)
DK96929292T 1995-08-25 1996-08-21 Anvendelse af lipider som hjælpemidler ved fremstilling af faste lægemiddelformer ved smelteekstruderingsfremgangsmåden DK0845982T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19531277A DE19531277A1 (de) 1995-08-25 1995-08-25 Verwendung von Lipiden als Hilfsmittel bei der Herstellung von festen Arzneiformen nach dem Schmelzextrusionsverfahren
PCT/EP1996/003667 WO1997007786A2 (fr) 1995-08-25 1996-08-21 Utilisation de lipides comme adjuvants dans la fabrication de formes medicamenteuses solides selon le procede d'extrusion de matiere fondue

Publications (1)

Publication Number Publication Date
DK0845982T3 true DK0845982T3 (da) 2002-03-25

Family

ID=7770352

Family Applications (1)

Application Number Title Priority Date Filing Date
DK96929292T DK0845982T3 (da) 1995-08-25 1996-08-21 Anvendelse af lipider som hjælpemidler ved fremstilling af faste lægemiddelformer ved smelteekstruderingsfremgangsmåden

Country Status (13)

Country Link
US (1) US6387401B2 (fr)
EP (1) EP0845982B1 (fr)
AR (1) AR003345A1 (fr)
AT (1) ATE210970T1 (fr)
AU (1) AU6875396A (fr)
BR (1) BR9610234A (fr)
CA (1) CA2227272C (fr)
DE (2) DE19531277A1 (fr)
DK (1) DK0845982T3 (fr)
ES (1) ES2170259T3 (fr)
HR (1) HRP960381A2 (fr)
WO (1) WO1997007786A2 (fr)
ZA (1) ZA967170B (fr)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU1787800A (en) * 1998-12-08 2000-06-26 Phares Pharmaceutical Research N.V. Phospholipid compositions
DE19916383A1 (de) * 1999-03-31 2000-10-05 Schering Ag Pharmazeutische Zusammensetzung mit einem Extrusionsstoff
BR0012869A (pt) * 1999-07-30 2002-05-21 Smithkline Beecham Plc Forma de dosagem farmacêutica de componentes múltiplos
US7364752B1 (en) 1999-11-12 2008-04-29 Abbott Laboratories Solid dispersion pharamaceutical formulations
CA2359945C (fr) * 1999-11-12 2011-04-26 Abbott Laboratories Inhibiteurs de cristallisation dans une dispersion solide
DE10026699A1 (de) * 2000-05-30 2001-12-06 Basf Ag Formulierung auf Heparin-, Glycosaminoglycan- oder Heparinoidbasis und Verwendung der Formulierung sowie der Formulierungsgrundlage
DE10026698A1 (de) * 2000-05-30 2001-12-06 Basf Ag Selbstemulgierende Wirkstoffformulierung und Verwendung dieser Formulierung
GB0102342D0 (en) 2001-01-30 2001-03-14 Smithkline Beecham Plc Pharmaceutical formulation
US7842308B2 (en) * 2001-01-30 2010-11-30 Smithkline Beecham Limited Pharmaceutical formulation
US20050175687A1 (en) * 2001-01-30 2005-08-11 Mcallister Stephen M. Pharmaceutical formulations
US7883721B2 (en) 2001-01-30 2011-02-08 Smithkline Beecham Limited Pharmaceutical formulation
TW200526274A (en) 2003-07-21 2005-08-16 Smithkline Beecham Plc Pharmaceutical formulations
US8025899B2 (en) 2003-08-28 2011-09-27 Abbott Laboratories Solid pharmaceutical dosage form
US8377952B2 (en) * 2003-08-28 2013-02-19 Abbott Laboratories Solid pharmaceutical dosage formulation
CA2549225A1 (fr) * 2003-12-04 2005-06-16 Pfizer Products Inc. Procede d'atomisation/congelation faisant appel a une extrudeuse pour la preparation de compositions medicamenteuses cristallines multiparticulaires contenant de preference un poloxamere et un glyceride
PE20060003A1 (es) * 2004-03-12 2006-03-01 Smithkline Beecham Plc Formulacion farmaceutica polimerica para moldear por inyeccion
CA2560165A1 (fr) * 2004-05-04 2005-11-10 Boehringer Ingelheim International Gmbh Forme pharmaceutique solide comprenant un antagoniste ltb4
EP1693045A1 (fr) * 2005-02-17 2006-08-23 Abbott GmbH & Co. KG Production de formes posologiques à partir de substances actives fondues
SI2200588T1 (sl) 2007-09-25 2019-08-30 Solubest Ltd. Sestavki, ki obsegajo lipofilne aktivne spojine, in postopek za njihovo pripravo
JP2011503048A (ja) 2007-11-08 2011-01-27 グラクソ グループ リミテッド 医薬製剤
WO2009150228A2 (fr) * 2008-06-13 2009-12-17 Glaxo Group Limited Formulations pharmaceutiques
CA2810837A1 (fr) 2010-09-22 2012-03-29 Joseph R. Luber Fabrication de comprimes a partir d'un melange pulverulent auquel de l'energie est appliquee
AT511581A1 (de) * 2011-05-26 2012-12-15 G L Pharma Gmbh Orale retardierende formulierung
US9511028B2 (en) 2012-05-01 2016-12-06 Johnson & Johnson Consumer Inc. Orally disintegrating tablet
DE102017106216A1 (de) * 2017-03-22 2018-09-27 Amw Gmbh Extrudierte Depotform zur anhaltenden Wirkstofffreisetzung

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2581541B1 (fr) 1985-05-09 1988-05-20 Rhone Poulenc Sante Nouvelles compositions pharmaceutiques permettant la liberation prolongee d'un principe actif et leur procede de preparation
DE4226753A1 (de) 1992-08-13 1994-02-17 Basf Ag Wirkstoffe enthaltende Zubereitungen in Form fester Teilchen
DE69530973T2 (de) * 1994-02-16 2004-05-19 Abbott Laboratories, Abbott Park Verfahren zur herstellung feinteiliger pharmazeutischer formulierungen
DE4413350A1 (de) 1994-04-18 1995-10-19 Basf Ag Retard-Matrixpellets und Verfahren zu ihrer Herstellung
US5965161A (en) 1994-11-04 1999-10-12 Euro-Celtique, S.A. Extruded multi-particulates
DE19504832A1 (de) * 1995-02-14 1996-08-22 Basf Ag Feste Wirkstoff-Zubereitungen

Also Published As

Publication number Publication date
EP0845982B1 (fr) 2001-12-19
DE59608516D1 (de) 2002-01-31
CA2227272C (fr) 2007-12-11
CA2227272A1 (fr) 1997-03-06
AU6875396A (en) 1997-03-19
BR9610234A (pt) 1999-06-29
US6387401B2 (en) 2002-05-14
WO1997007786A3 (fr) 1997-04-03
DE19531277A1 (de) 1997-02-27
WO1997007786A2 (fr) 1997-03-06
ATE210970T1 (de) 2002-01-15
US20010007664A1 (en) 2001-07-12
ZA967170B (en) 1998-03-02
EP0845982A2 (fr) 1998-06-10
HRP960381A2 (en) 1998-02-28
AR003345A1 (es) 1998-07-08
ES2170259T3 (es) 2002-08-01

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