ZA967170B - Use of lipids as aids in the production of solid drug forms by melt extrusion. - Google Patents

Use of lipids as aids in the production of solid drug forms by melt extrusion.

Info

Publication number
ZA967170B
ZA967170B ZA9607170A ZA967170A ZA967170B ZA 967170 B ZA967170 B ZA 967170B ZA 9607170 A ZA9607170 A ZA 9607170A ZA 967170 A ZA967170 A ZA 967170A ZA 967170 B ZA967170 B ZA 967170B
Authority
ZA
South Africa
Prior art keywords
lipids
aids
production
melt extrusion
solid drug
Prior art date
Application number
ZA9607170A
Other languages
English (en)
Inventor
Joerg Rosenberg
Joerg Breitenbach
Original Assignee
Basf Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Basf Ag filed Critical Basf Ag
Publication of ZA967170B publication Critical patent/ZA967170B/xx

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2022Organic macromolecular compounds
    • A61K9/205Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2013Organic compounds, e.g. phospholipids, fats
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2095Tabletting processes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2013Organic compounds, e.g. phospholipids, fats
    • A61K9/2018Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
ZA9607170A 1995-08-25 1996-08-23 Use of lipids as aids in the production of solid drug forms by melt extrusion. ZA967170B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19531277A DE19531277A1 (de) 1995-08-25 1995-08-25 Verwendung von Lipiden als Hilfsmittel bei der Herstellung von festen Arzneiformen nach dem Schmelzextrusionsverfahren

Publications (1)

Publication Number Publication Date
ZA967170B true ZA967170B (en) 1998-03-02

Family

ID=7770352

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA9607170A ZA967170B (en) 1995-08-25 1996-08-23 Use of lipids as aids in the production of solid drug forms by melt extrusion.

Country Status (13)

Country Link
US (1) US6387401B2 (fr)
EP (1) EP0845982B1 (fr)
AR (1) AR003345A1 (fr)
AT (1) ATE210970T1 (fr)
AU (1) AU6875396A (fr)
BR (1) BR9610234A (fr)
CA (1) CA2227272C (fr)
DE (2) DE19531277A1 (fr)
DK (1) DK0845982T3 (fr)
ES (1) ES2170259T3 (fr)
HR (1) HRP960381A2 (fr)
WO (1) WO1997007786A2 (fr)
ZA (1) ZA967170B (fr)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU1787800A (en) * 1998-12-08 2000-06-26 Phares Pharmaceutical Research N.V. Phospholipid compositions
DE19916383A1 (de) * 1999-03-31 2000-10-05 Schering Ag Pharmazeutische Zusammensetzung mit einem Extrusionsstoff
NZ516733A (en) * 1999-07-30 2004-03-26 Smithkline Beecham Plc Pharmaceutical formulations for oral dosing that are dosage forms comprising two or more connected sub-units
US7364752B1 (en) 1999-11-12 2008-04-29 Abbott Laboratories Solid dispersion pharamaceutical formulations
WO2001034119A2 (fr) * 1999-11-12 2001-05-17 Abbott Laboratories Inhibiteurs de cristallisation dans une dispersion solide
DE10026698A1 (de) * 2000-05-30 2001-12-06 Basf Ag Selbstemulgierende Wirkstoffformulierung und Verwendung dieser Formulierung
DE10026699A1 (de) * 2000-05-30 2001-12-06 Basf Ag Formulierung auf Heparin-, Glycosaminoglycan- oder Heparinoidbasis und Verwendung der Formulierung sowie der Formulierungsgrundlage
US7883721B2 (en) 2001-01-30 2011-02-08 Smithkline Beecham Limited Pharmaceutical formulation
GB0102342D0 (en) 2001-01-30 2001-03-14 Smithkline Beecham Plc Pharmaceutical formulation
US7842308B2 (en) 2001-01-30 2010-11-30 Smithkline Beecham Limited Pharmaceutical formulation
US20050175687A1 (en) * 2001-01-30 2005-08-11 Mcallister Stephen M. Pharmaceutical formulations
TW200526274A (en) 2003-07-21 2005-08-16 Smithkline Beecham Plc Pharmaceutical formulations
US8377952B2 (en) * 2003-08-28 2013-02-19 Abbott Laboratories Solid pharmaceutical dosage formulation
US8025899B2 (en) 2003-08-28 2011-09-27 Abbott Laboratories Solid pharmaceutical dosage form
CA2549225A1 (fr) * 2003-12-04 2005-06-16 Pfizer Products Inc. Procede d'atomisation/congelation faisant appel a une extrudeuse pour la preparation de compositions medicamenteuses cristallines multiparticulaires contenant de preference un poloxamere et un glyceride
PE20060003A1 (es) * 2004-03-12 2006-03-01 Smithkline Beecham Plc Formulacion farmaceutica polimerica para moldear por inyeccion
CA2560165A1 (fr) * 2004-05-04 2005-11-10 Boehringer Ingelheim International Gmbh Forme pharmaceutique solide comprenant un antagoniste ltb4
EP1693045A1 (fr) 2005-02-17 2006-08-23 Abbott GmbH & Co. KG Production de formes posologiques à partir de substances actives fondues
SI2200588T1 (sl) * 2007-09-25 2019-08-30 Solubest Ltd. Sestavki, ki obsegajo lipofilne aktivne spojine, in postopek za njihovo pripravo
JP2011503048A (ja) 2007-11-08 2011-01-27 グラクソ グループ リミテッド 医薬製剤
WO2009150228A2 (fr) * 2008-06-13 2009-12-17 Glaxo Group Limited Formulations pharmaceutiques
AU2011306065B2 (en) 2010-09-22 2015-03-19 Mcneil-Ppc, Inc. Manufacture of tablets from energy-applied powder blend
AT511581A1 (de) * 2011-05-26 2012-12-15 G L Pharma Gmbh Orale retardierende formulierung
US9511028B2 (en) 2012-05-01 2016-12-06 Johnson & Johnson Consumer Inc. Orally disintegrating tablet
DE102017106216A1 (de) * 2017-03-22 2018-09-27 Amw Gmbh Extrudierte Depotform zur anhaltenden Wirkstofffreisetzung

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2581541B1 (fr) 1985-05-09 1988-05-20 Rhone Poulenc Sante Nouvelles compositions pharmaceutiques permettant la liberation prolongee d'un principe actif et leur procede de preparation
DE4226753A1 (de) 1992-08-13 1994-02-17 Basf Ag Wirkstoffe enthaltende Zubereitungen in Form fester Teilchen
CA2182282C (fr) 1994-02-16 2006-04-18 Jacqueline E. Briskin Mode de preparation de formulations pharmaceutiques a fines particules
DE4413350A1 (de) * 1994-04-18 1995-10-19 Basf Ag Retard-Matrixpellets und Verfahren zu ihrer Herstellung
US5965161A (en) * 1994-11-04 1999-10-12 Euro-Celtique, S.A. Extruded multi-particulates
DE19504832A1 (de) * 1995-02-14 1996-08-22 Basf Ag Feste Wirkstoff-Zubereitungen

Also Published As

Publication number Publication date
ATE210970T1 (de) 2002-01-15
DE19531277A1 (de) 1997-02-27
US20010007664A1 (en) 2001-07-12
WO1997007786A2 (fr) 1997-03-06
DK0845982T3 (da) 2002-03-25
ES2170259T3 (es) 2002-08-01
WO1997007786A3 (fr) 1997-04-03
US6387401B2 (en) 2002-05-14
CA2227272A1 (fr) 1997-03-06
EP0845982A2 (fr) 1998-06-10
EP0845982B1 (fr) 2001-12-19
HRP960381A2 (en) 1998-02-28
AR003345A1 (es) 1998-07-08
AU6875396A (en) 1997-03-19
BR9610234A (pt) 1999-06-29
DE59608516D1 (de) 2002-01-31
CA2227272C (fr) 2007-12-11

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