DK0859785T3 - Cycliske peptidanaloge af somatostatin - Google Patents

Cycliske peptidanaloge af somatostatin

Info

Publication number: DK0859785T3
Authority: DK; Denmark
Prior art keywords: somatostatin; cyclic peptide; peptide analogues; terminus residue; analogues
Prior art date: 1995-09-29

Application number

DK96929913T

Other languages

Danish (da)

English (en)

Inventor

David H Coy

John E Taylor

Original Assignee

Biomeasure Inc

Univ Tulane

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1995-09-29

Filing date

1996-09-04

Publication date

2001-08-27

1996-09-04 Application filed by Biomeasure Inc, Univ Tulane filed Critical Biomeasure Inc

2001-08-27 Application granted granted Critical

2001-08-27 Publication of DK0859785T3 publication Critical patent/DK0859785T3/da

Links

108010069514 Cyclic Peptides Proteins 0.000 title abstract 2
102000001189 Cyclic Peptides Human genes 0.000 title abstract 2
NHXLMOGPVYXJNR-ATOGVRKGSA-N somatostatin Chemical class C([C@H]1C(=O)N[C@H](C(N[C@@H](CO)C(=O)N[C@@H](CSSC[C@@H](C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC=2C=CC=CC=2)C(=O)N[C@@H](CC=2C=CC=CC=2)C(=O)N[C@@H](CC=2C3=CC=CC=C3NC=2)C(=O)N[C@@H](CCCCN)C(=O)N[C@H](C(=O)N1)[C@@H](C)O)NC(=O)CNC(=O)[C@H](C)N)C(O)=O)=O)[C@H](O)C)C1=CC=CC=C1 NHXLMOGPVYXJNR-ATOGVRKGSA-N 0.000 title abstract 2
102000005157 Somatostatin Human genes 0.000 abstract 1
108010056088 Somatostatin Proteins 0.000 abstract 1
229960000553 somatostatin Drugs 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/655—Somatostatins
- C07K14/6555—Somatostatins at least 1 amino acid in D-form
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/02—Drugs for disorders of the endocrine system of the hypothalamic hormones, e.g. TRH, GnRH, CRH, GRH, somatostatin
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S930/00—Peptide or protein sequence
- Y10S930/01—Peptide or protein sequence
- Y10S930/16—Somatostatin; related peptides

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
Medicinal Chemistry (AREA)
General Health & Medical Sciences (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Molecular Biology (AREA)
Genetics & Genomics (AREA)
Endocrinology (AREA)
Biophysics (AREA)
Biochemistry (AREA)
Zoology (AREA)
Toxicology (AREA)
Gastroenterology & Hepatology (AREA)
Veterinary Medicine (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmacology & Pharmacy (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Diabetes (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Peptides Or Proteins (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

DK96929913T 1995-09-29 1996-09-04 Cycliske peptidanaloge af somatostatin DK0859785T3 (da)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
US463395P	1995-09-29	1995-09-29
US08/578,037 US5708135A (en)	1995-09-29	1995-12-26	Cyclic peptide analogs of somatostatin
PCT/US1996/014230 WO1997011962A1 (en)	1995-09-29	1996-09-04	Cyclic peptide analogs of somatostatin

Publications (1)

Publication Number	Publication Date
DK0859785T3 true DK0859785T3 (da)	2001-08-27

Family

ID=26673267

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK96929913T DK0859785T3 (da)	1995-09-29	1996-09-04	Cycliske peptidanaloge af somatostatin

Country Status (23)

Country	Link
US (2)	US5708135A (de)
EP (1)	EP0859785B1 (de)
JP (1)	JP3983806B2 (de)
KR (1)	KR100430716B1 (de)
CN (1)	CN1154657C (de)
AT (1)	ATE201696T1 (de)
AU (1)	AU711423B2 (de)
BR (1)	BR9610725A (de)
CA (1)	CA2229544C (de)
CZ (1)	CZ289282B6 (de)
DE (1)	DE69613137T2 (de)
DK (1)	DK0859785T3 (de)
ES (1)	ES2158340T3 (de)
GR (1)	GR3036447T3 (de)
HU (1)	HU221979B1 (de)
IL (2)	IL155693A0 (de)
NO (1)	NO318369B1 (de)
NZ (1)	NZ316822A (de)
PL (1)	PL325959A1 (de)
PT (1)	PT859785E (de)
SK (1)	SK29298A3 (de)
TW (1)	TW514642B (de)
WO (1)	WO1997011962A1 (de)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US7238340B1 (en) *	1991-11-27	2007-07-03	Cis Bio International	Monoamine, diamide, thiol-containing metal chelating agents
US5708135A (en) *	1995-09-29	1998-01-13	Biomeasure Incorporated	Cyclic peptide analogs of somatostatin
PL334089A1 (en) *	1996-12-04	2000-01-31	Sod Conseils Rech Applic	Compounds antagonistic in respect to somatostatin
US6262229B1 (en)	1996-12-04	2001-07-17	Biomeasure Incorporated	Somatostatin antagonists
EP1332762A1 (de) *	1997-05-01	2003-08-06	Cedars-Sinai Medical Center	Methode zur Behandlung von Hyperprolaktinämia und Prolaktinomen
PT979098E (pt) *	1997-05-01	2003-07-31	Cedars Sinai Medical Center	Metodo para o tratamento da hiperprolactinemia e de prolactinomas
US5972893A (en) *	1997-05-06	1999-10-26	Cedars-Sinai Medical Center	Method of treating hyperprolactinemia and prolactinomas
AU7655098A (en) *	1997-05-13	1998-12-08	Societe De Conseils De Recherches Et D'applications Scientifiques (S.C.R.A.S.)	Somatostatin and somatostatin agonists for decreasing body weight
US6004928A (en) *	1997-05-13	1999-12-21	Biomeasure, Incorporated	Method of treating hyperlipidemia
PT980253E (pt) *	1997-05-13	2004-08-31	Conseils De Rec Appl Scient S	Somatostatina e agonistas de somatostatina para tratar a insensibilidade a insulina e a sindrome x
EP0981364B1 (de) *	1997-05-13	2006-03-01	Societe De Conseils De Recherches Et D'applications Scientifiques S.A.S.	Methoden und zusammensetzungen zur behandlung der hyperlipidämie
US6465613B1 (en)	1998-11-19	2002-10-15	Tulane University	Hydrophilic somatostatin analogs
US6903074B1 (en)	1999-06-04	2005-06-07	Societe De Conseils De Recherches Et D'applications Scientifiques, S.A.S.	Neuromedin b and somatostatin receptor agonists
US6864234B1 (en)	1999-06-25	2005-03-08	Societe De Conseils De Recherches Et D'applications Scientifiques, S.A.S.	Somatostatin agonists
US6358491B1 (en)	1999-08-27	2002-03-19	Berlex Laboratories, Inc.	Somatostatin analogs
US6579967B1 (en)	1999-12-14	2003-06-17	The Salk Institute For Biological Studies	Receptor-selective somatostatin analogs
US7019109B2 (en) *	2001-03-16	2006-03-28	The Salk Institute For Bilogical Studies	SSTR1-selective analogs
BR0212897A (pt)	2001-09-21	2004-08-24	Univ Tulane	Conjugados de análogos de somatostatina ou bombesina diagnóstica ou terapêutica e usos dos mesmos
US7771727B2 (en) *	2002-03-01	2010-08-10	The Administrators Of The Tulane Educational Fund	Conjugates of therapeutic or cytotoxic agents and biologically active peptides
AU2003259172A1 (en) *	2002-07-24	2004-02-09	The Salk Institute For Biological Studies	Receptor (sstr4)- selective somatostatin analogs
JP2006522100A (ja) *	2003-03-10	2006-09-28	バイオジェンアイデックインク	標的化ペプチドに対するチオール媒介性薬物結合
CN100475271C (zh)	2003-08-20	2009-04-08	加利福尼亚大学董事会	具有抑制生长激素释放活性的促生长素抑制素类似物
ES2410207T3 (es)	2006-10-16	2013-07-01	The Salk Institute For Biological Studies	Antagonistas de la somatostatina selectivos para receptor(SSTR2)
US8691761B2 (en)	2006-10-16	2014-04-08	Jean E. F. Rivier	Somatostatin receptor 2 antagonists
JP5963764B2 (ja)	2010-11-29	2016-08-03	サノフィ−アベンティス・ドイチュラント・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツング	自動リザーバ係合を備えた薬用モジュール

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE2416048A1 (de) *	1974-04-03	1975-10-30	Hoechst Ag	Neue peptide mit biologischer wirkung
US4133782A (en) *	1976-06-07	1979-01-09	The Salk Institute For Biological Studies	Somatostatin analogs with dissociated biological activities
US4211693A (en) *	1977-09-20	1980-07-08	The Salk Institute For Biological Studies	Peptides with para-substituted phenylalanine
US4225472A (en) *	1979-05-29	1980-09-30	American Home Products Corporation	Truncated somatostatin analogs
FR2523125A1 (fr) *	1982-03-08	1983-09-16	Sanofi Sa	Analogues de la somatostatine a activite biologique modifiee et medicaments en contenant
US4428942A (en) *	1982-05-17	1984-01-31	The Salk Institute For Biological Studies	Analogs of somatostatin
GB8318552D0 (en) *	1983-07-08	1983-08-10	Sandoz Ltd	Organic compounds
US4853371A (en) *	1986-06-17	1989-08-01	The Administrators Of The Tulane Educational Fund	Therapeutic somatostatin analogs
US4798821A (en) *	1987-03-02	1989-01-17	Merck & Co., Inc.	Antihypertensive therapy for diabetics
AU639371B2 (en) *	1987-07-10	1993-07-22	Novartis Ag	Method of treating breast cancer
WO1991009056A1 (en) *	1989-12-08	1991-06-27	The Administrators Of The Tulane Educational Fund	Octapeptide analogs of somatostatin having threonine at the sixth position
JPH03252783A (ja) *	1990-03-02	1991-11-12	Hitachi Ltd	データ処理装置
JPH04227540A (ja) *	1990-04-04	1992-08-17	Hitachi Ltd	演算処理装置及びディジタル信号処理プロセッサ
EP0945504A3 (de) *	1992-12-11	1999-12-08	The University Of Florida	Stoffe und verfahren zur Schädlingskontrolle
JP3904244B2 (ja) *	1993-09-17	2007-04-11	株式会社ルネサステクノロジ	シングル・チップ・データ処理装置
US5708135A (en) *	1995-09-29	1998-01-13	Biomeasure Incorporated	Cyclic peptide analogs of somatostatin
JP3767085B2 (ja) *	1996-09-04	2006-04-19	セイコーエプソン株式会社	情報処理回路及びマイクロコンピュータ

1995
- 1995-12-26 US US08/578,037 patent/US5708135A/en not_active Expired - Lifetime
1996
- 1996-09-04 HU HU9802372A patent/HU221979B1/hu not_active IP Right Cessation
- 1996-09-04 PL PL96325959A patent/PL325959A1/xx unknown
- 1996-09-04 DK DK96929913T patent/DK0859785T3/da active
- 1996-09-04 ES ES96929913T patent/ES2158340T3/es not_active Expired - Lifetime
- 1996-09-04 WO PCT/US1996/014230 patent/WO1997011962A1/en not_active Ceased
- 1996-09-04 CA CA002229544A patent/CA2229544C/en not_active Expired - Fee Related
- 1996-09-04 CN CNB961971770A patent/CN1154657C/zh not_active Expired - Fee Related
- 1996-09-04 IL IL15569396A patent/IL155693A0/xx unknown
- 1996-09-04 EP EP96929913A patent/EP0859785B1/de not_active Expired - Lifetime
- 1996-09-04 AT AT96929913T patent/ATE201696T1/de not_active IP Right Cessation
- 1996-09-04 JP JP51344497A patent/JP3983806B2/ja not_active Expired - Fee Related
- 1996-09-04 CZ CZ1998489A patent/CZ289282B6/cs not_active IP Right Cessation
- 1996-09-04 KR KR10-1998-0701664A patent/KR100430716B1/ko not_active Expired - Fee Related
- 1996-09-04 PT PT96929913T patent/PT859785E/pt unknown
- 1996-09-04 SK SK292-98A patent/SK29298A3/sk unknown
- 1996-09-04 AU AU69145/96A patent/AU711423B2/en not_active Ceased
- 1996-09-04 IL IL12335796A patent/IL123357A0/xx unknown
- 1996-09-04 DE DE69613137T patent/DE69613137T2/de not_active Expired - Lifetime
- 1996-09-04 NZ NZ316822A patent/NZ316822A/en unknown
- 1996-09-04 BR BR9610725A patent/BR9610725A/pt not_active IP Right Cessation
- 1996-09-26 TW TW085112054A patent/TW514642B/zh not_active IP Right Cessation
1998
- 1998-01-13 US US09/006,348 patent/US6001801A/en not_active Expired - Fee Related
- 1998-03-27 NO NO19981395A patent/NO318369B1/no unknown
2001
- 2001-08-27 GR GR20010401297T patent/GR3036447T3/el not_active IP Right Cessation

Also Published As

Publication number	Publication date
EP0859785A1 (de)	1998-08-26
ATE201696T1 (de)	2001-06-15
SK29298A3 (en)	1998-08-05
JP3983806B2 (ja)	2007-09-26
NZ316822A (en)	1999-10-28
DE69613137D1 (de)	2001-07-05
DE69613137T2 (de)	2001-11-15
PL325959A1 (en)	1998-08-17
KR100430716B1 (ko)	2004-09-08
GR3036447T3 (en)	2001-11-30
WO1997011962A1 (en)	1997-04-03
CA2229544A1 (en)	1997-04-03
ES2158340T3 (es)	2001-09-01
NO981395L (no)	1998-03-27
AU6914596A (en)	1997-04-17
BR9610725A (pt)	1999-07-13
HUP9802372A2 (hu)	1999-02-01
CZ289282B6 (cs)	2001-12-12
AU711423B2 (en)	1999-10-14
PT859785E (pt)	2001-11-30
CA2229544C (en)	2007-11-20
US6001801A (en)	1999-12-14
EP0859785A4 (de)	1999-05-26
NO981395D0 (no)	1998-03-27
KR20000004896A (ko)	2000-01-25
IL123357A0 (en)	1998-09-24
HUP9802372A3 (en)	2000-03-28
IL155693A0 (en)	2003-11-23
CZ48998A3 (cs)	1998-07-15
CN1197460A (zh)	1998-10-28
JPH11512707A (ja)	1999-11-02
EP0859785B1 (de)	2001-05-30
NO318369B1 (no)	2005-03-14
CN1154657C (zh)	2004-06-23
HU221979B1 (hu)	2003-03-28
US5708135A (en)	1998-01-13
TW514642B (en)	2002-12-21

Publication	Publication Date	Title
ATE201696T1 (de)	2001-06-15	Zyklische peptidanaloga von somatostatin
ES2192620T3 (es)	2003-10-16	Polipeptido receptor de il-13.
ES2169251T3 (es)	2002-07-01	Peptidos de somatostatina.
DE69432758D1 (en)	2003-07-03	Therapeutisch wirksame peptidderivate
DE69841105D1 (de)	2009-10-08	Chemokine peptide, varianten, derivate und analoge. ihre verwendung in methode für die hemmung oder erhöhung von einer entzündungsreaktion
FI961044A0 (fi)	1996-03-06	Kininogeeni-inhibiittorit
ATE419268T1 (de)	2009-01-15	Haemasterlin analoge
ATE330966T1 (de)	2006-07-15	Somatostatin-antagonisten
ATE480558T1 (de)	2010-09-15	Auf scf peptid basiertes basolaterales sortiersignal und inhibitoren dafür
ATE230758T1 (de)	2003-01-15	Peptid mit affinität zu gerinnungsfaktor viii
CO4700528A1 (es)	1998-12-29	Peptidos de somatostatina
ATE385805T1 (de)	2008-03-15	Neue peptide
IL92551A0 (en)	1990-08-31	Anticoagulant peptides
DE69427363D1 (de)	2001-07-05	Plättchenaggregationsinhibierende peptide
GR3021660T3 (en)	1997-02-28	Anticoagulant peptides
EP0650976A4 (de)	1997-10-01	Allergenisches peptid.
DE69420044D1 (de)	1999-09-16	Blutregulierende peptide
NO962204D0 (no)	1996-05-30	Dobbeltkjedede hemoregulatoriske peptider
DE69006311D1 (de)	1994-03-10	Antimetastatische peptide.
ECSP961798A (es)	1997-11-28	Peptidos de somatostatina
EP0697112A4 (de)	1998-07-29	C-terminale sequenzierung von peptiden, die prolin enthalten können