DK0870022T3 - Immunstimulerende sammensætning og fremgangsmåde - Google Patents
Immunstimulerende sammensætning og fremgangsmådeInfo
- Publication number
- DK0870022T3 DK0870022T3 DK96944879T DK96944879T DK0870022T3 DK 0870022 T3 DK0870022 T3 DK 0870022T3 DK 96944879 T DK96944879 T DK 96944879T DK 96944879 T DK96944879 T DK 96944879T DK 0870022 T3 DK0870022 T3 DK 0870022T3
- Authority
- DK
- Denmark
- Prior art keywords
- polypeptide
- disclosed
- therapeutic compositions
- immunostimulatory composition
- antigen
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/0005—Vertebrate antigens
- A61K39/0011—Cancer antigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/0005—Vertebrate antigens
- A61K39/0011—Cancer antigens
- A61K39/001136—Cytokines
- A61K39/001139—Colony stimulating factors [CSF]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/0005—Vertebrate antigens
- A61K39/0011—Cancer antigens
- A61K39/001193—Prostate associated antigens e.g. Prostate stem cell antigen [PSCA]; Prostate carcinoma tumor antigen [PCTA]; PAP or PSGR
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/385—Haptens or antigens, bound to carriers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/4746—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used p53
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/52—Cytokines; Lymphokines; Interferons
- C07K14/53—Colony-stimulating factor [CSF]
- C07K14/535—Granulocyte CSF; Granulocyte-macrophage CSF
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/71—Receptors; Cell surface antigens; Cell surface determinants for growth factors; for growth regulators
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/16—Hydrolases (3) acting on ester bonds (3.1)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/515—Animal cells
- A61K2039/5154—Antigen presenting cells [APCs], e.g. dendritic cells or macrophages
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/60—Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
- A61K2039/6031—Proteins
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Immunology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Genetics & Genomics (AREA)
- Microbiology (AREA)
- Zoology (AREA)
- Mycology (AREA)
- Epidemiology (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Gastroenterology & Hepatology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Toxicology (AREA)
- Biophysics (AREA)
- Oncology (AREA)
- Cell Biology (AREA)
- Wood Science & Technology (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Developmental Biology & Embryology (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Enzymes And Modification Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US08/579,823 US6080409A (en) | 1995-12-28 | 1995-12-28 | Immunostimulatory method |
| PCT/US1996/020241 WO1997024438A1 (en) | 1995-12-28 | 1996-12-23 | Immunostimulatory composition and method |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK0870022T3 true DK0870022T3 (da) | 2007-05-21 |
Family
ID=24318489
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK96944879T DK0870022T3 (da) | 1995-12-28 | 1996-12-23 | Immunstimulerende sammensætning og fremgangsmåde |
Country Status (12)
| Country | Link |
|---|---|
| US (3) | US6080409A (da) |
| EP (1) | EP0870022B1 (da) |
| JP (1) | JP3908277B2 (da) |
| AT (1) | ATE353363T1 (da) |
| AU (1) | AU716783B2 (da) |
| CA (1) | CA2241373C (da) |
| DE (1) | DE69636891T2 (da) |
| DK (1) | DK0870022T3 (da) |
| ES (1) | ES2281087T3 (da) |
| NZ (2) | NZ326092A (da) |
| PT (1) | PT870022E (da) |
| WO (1) | WO1997024438A1 (da) |
Families Citing this family (101)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20040258688A1 (en) * | 1995-01-31 | 2004-12-23 | Daniel Hawiger | Enhanced antigen delivery and modulation of the immune response therefrom |
| US20020187131A1 (en) * | 1995-01-31 | 2002-12-12 | Daniel Hawiger | Enhanced antigen delivery and modulation of the immune response therefrom |
| US20080286228A1 (en) * | 1995-10-20 | 2008-11-20 | Tarantolo Stefano R | Compositions and methods for enhancing immune responses mediated by antigen-presenting cells |
| AU703120B2 (en) | 1995-10-20 | 1999-03-18 | University Of Nebraska Board Of Regents | Composition and methods for enhancing immune responses mediated by antigen-presenting cells |
| US6096313A (en) * | 1996-02-09 | 2000-08-01 | Ludwig Institute For Cancer Research | Compositions containing immunogenic molecules and granulocyte-macrophage colony stimulating factor, as an adjuvant |
| US6942862B2 (en) * | 1996-04-01 | 2005-09-13 | University Of Washington | Methods and compositions to generate immunity in humans against self tumor antigens by immunization with homologous foreign proteins |
| KR20000022445A (ko) * | 1996-07-10 | 2000-04-25 | 크리스토퍼 엘. 와이트, 스코트 지. 홀퀴스트, 스티븐 엘. 말라스카 | 수상돌기 세포의 활성화 방법 |
| DE69840326D1 (de) * | 1997-03-27 | 2009-01-22 | Csl Ltd | Steigerung der immunantwort unter verwendung von zielgerichteten molekülen |
| US6642013B1 (en) * | 1997-08-21 | 2003-11-04 | The University Of Arkansas For Medical Sciences | Extracellular serine protease |
| US7157084B2 (en) * | 1997-08-21 | 2007-01-02 | The Board Of Trustees Of The University Of Arkansas System | Extracellular serine protease |
| US6872518B2 (en) | 1997-09-22 | 2005-03-29 | University Of Rochester | Methods for selecting polynucleotides encoding T cell epitopes |
| PT1037927E (pt) | 1997-12-08 | 2004-10-29 | Emd Lexigen Res Ct Corp | Proteinas de fusao heterodimericas uteis para imunoterapia de abordagem selectiva e estimulacao imunologica geral |
| US20030105294A1 (en) * | 1998-02-25 | 2003-06-05 | Stephen Gillies | Enhancing the circulating half life of antibody-based fusion proteins |
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| US7351546B2 (en) | 1998-09-22 | 2008-04-01 | Becton, Dickinson And Company | Flow cytometric, whole blood dendritic cell immune function assay |
| US6495333B1 (en) | 1998-09-22 | 2002-12-17 | Becton Dickinson And Company | Flow cytometric, whole blood dendritic cell immune function assay |
| ATE407206T1 (de) * | 1998-11-10 | 2008-09-15 | Univ Rochester | Methoden zu herstellung von genbanken |
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| CN105647970A (zh) * | 2016-02-22 | 2016-06-08 | 河北利同康生物科技有限公司 | 前列腺癌特异性pap-gm-csf-il-6基因重组融合蛋白及其制备方法 |
| CN110079539B (zh) * | 2018-01-25 | 2022-07-01 | 上海惠盾因泰生物科技有限公司 | 前列腺酸性磷酸酶/粒-巨噬细胞集落刺激因子制备方法 |
| WO2019183924A1 (en) | 2018-03-30 | 2019-10-03 | Syz Cell Therapy Co. | Improved multiple antigen specific cell therapy methods |
| AU2019333181B2 (en) * | 2018-08-31 | 2025-10-02 | The Research Institute At Nationwide Children's Hospital | Chimeric oncolytic herpesvirus that stimulate an antitumor immune response |
| US20220088183A1 (en) * | 2018-08-31 | 2022-03-24 | The Research Institute At Nationwide Children's Hospital | Chimeric oncolytic herpesvirus that stimulates an antitumor immune response |
| CN110358735B (zh) * | 2019-06-24 | 2021-09-21 | 广州安捷生物医学技术有限公司 | 一种ctl细胞的制备方法及应用 |
| EP3868401A1 (en) | 2020-02-21 | 2021-08-25 | Assistance Publique Hôpitaux de Paris | Optimization of peptide-melanin binding |
| CA3192967A1 (en) | 2020-10-15 | 2022-04-21 | Aiquan CHANG | Recombinant adeno-associated virus vectors with cd14 promoter and use thereof |
| WO2022174052A1 (en) * | 2021-02-12 | 2022-08-18 | The Wistar Institute Of Anatomy And Biology | Consensus prostate antigens, nucleic acid molecules encoding the same, and vaccines and uses comprising the same |
| EP4382121A1 (en) | 2022-12-07 | 2024-06-12 | Altevax | Vaccines against ptprz1-positive tumors |
| EP4420677A1 (en) | 2023-02-22 | 2024-08-28 | Altevax | Vaccines against tert-positive tumors |
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| US5078996A (en) * | 1985-08-16 | 1992-01-07 | Immunex Corporation | Activation of macrophage tumoricidal activity by granulocyte-macrophage colony stimulating factor |
| US5194254A (en) * | 1986-05-06 | 1993-03-16 | Connaught Laboratories Limited | Enhancement of antigen immunogenicity |
| US5019384A (en) * | 1986-06-30 | 1991-05-28 | Massachusetts Institute Of Technology | Immunonodulating compositions and their use |
| US4861589A (en) * | 1987-03-23 | 1989-08-29 | Trustees Of Boston University | Method for therapeutically treating abnormal cells expressing a major histocompatibility complex class II antigen using cytolytic inducer T4 cells |
| GB8722741D0 (en) * | 1987-09-28 | 1987-11-04 | Hoffmann La Roche | Induction of cytotoxic t cell response |
| WO1989006692A1 (en) * | 1988-01-12 | 1989-07-27 | Genentech, Inc. | Method of treating tumor cells by inhibiting growth factor receptor function |
| EP0406857B1 (en) * | 1989-07-07 | 1995-05-24 | Takeda Chemical Industries, Ltd. | Proteins and production thereof |
| JPH04506662A (ja) * | 1989-07-14 | 1992-11-19 | アメリカン・サイアナミド・カンパニー | 接合体ワクチンのためのサイトカイニンおよびホルモンのキヤリヤー |
| US20030072751A1 (en) * | 1990-03-14 | 2003-04-17 | Heribert Bohlen | Idiotypic vaccination against b cell lymphoma |
| AU687733B2 (en) * | 1992-04-01 | 1998-03-05 | Rockefeller University, The | Method for in vitro proliferation of dendritic cell precursors and their use to produce immunogens |
| DE69333433T2 (de) * | 1992-04-01 | 2004-12-02 | The Rockefeller University | Verfahren zur in vitro kultivierung dendritischer vorläuferzellen und deren verwendung zur immunogen herstellung |
| US5633234A (en) * | 1993-01-22 | 1997-05-27 | The Johns Hopkins University | Lysosomal targeting of immunogens |
| WO1994021287A1 (en) * | 1993-03-15 | 1994-09-29 | The Government Of The United States Of America As Represented By The Department Of Health And Human Services | Peptide coated dendritic cells as immunogens |
| US5550214A (en) * | 1994-02-10 | 1996-08-27 | Brigham And Women's Hospital | Isolated antigenic oncogene peptide fragments and uses |
| US5820866A (en) * | 1994-03-04 | 1998-10-13 | National Jewish Center For Immunology And Respiratory Medicine | Product and process for T cell regulation |
| CA2192655A1 (en) * | 1994-06-14 | 1995-12-21 | Edgar G. Engleman | Methods for in vivo t cell activation by antigen-pulsed dendritic cells |
| AU686840B2 (en) * | 1994-07-07 | 1998-02-12 | Immunex Corporation | Fusion proteins comprising GM-CSF and antigens and their expression in yeast |
| GB9501079D0 (en) * | 1995-01-19 | 1995-03-08 | Bioinvent Int Ab | Activation of T-cells |
| AU5801896A (en) * | 1995-05-23 | 1996-12-11 | Scripps Research Institute, The | Antigen-specific activation of unprimed cd8+ t cells |
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1995
- 1995-12-28 US US08/579,823 patent/US6080409A/en not_active Expired - Lifetime
-
1996
- 1996-12-23 CA CA2241373A patent/CA2241373C/en not_active Expired - Lifetime
- 1996-12-23 PT PT96944879T patent/PT870022E/pt unknown
- 1996-12-23 NZ NZ326092A patent/NZ326092A/xx not_active IP Right Cessation
- 1996-12-23 ES ES96944879T patent/ES2281087T3/es not_active Expired - Lifetime
- 1996-12-23 WO PCT/US1996/020241 patent/WO1997024438A1/en not_active Ceased
- 1996-12-23 EP EP96944879A patent/EP0870022B1/en not_active Expired - Lifetime
- 1996-12-23 JP JP52441897A patent/JP3908277B2/ja not_active Expired - Fee Related
- 1996-12-23 AT AT96944879T patent/ATE353363T1/de active
- 1996-12-23 DE DE69636891T patent/DE69636891T2/de not_active Expired - Lifetime
- 1996-12-23 AU AU13380/97A patent/AU716783B2/en not_active Expired
- 1996-12-23 DK DK96944879T patent/DK0870022T3/da active
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1998
- 1998-09-03 US US09/146,283 patent/US5976546A/en not_active Expired - Lifetime
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1999
- 1999-06-24 US US09/344,195 patent/US6210662B1/en not_active Expired - Lifetime
- 1999-10-28 NZ NZ500665A patent/NZ500665A/en not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| US6080409A (en) | 2000-06-27 |
| PT870022E (pt) | 2007-04-30 |
| DE69636891T2 (de) | 2007-12-06 |
| AU1338097A (en) | 1997-07-28 |
| NZ500665A (en) | 2005-06-24 |
| CA2241373C (en) | 2013-04-09 |
| AU716783B2 (en) | 2000-03-09 |
| JP2000502567A (ja) | 2000-03-07 |
| EP0870022B1 (en) | 2007-02-07 |
| ATE353363T1 (de) | 2007-02-15 |
| US6210662B1 (en) | 2001-04-03 |
| WO1997024438A1 (en) | 1997-07-10 |
| CA2241373A1 (en) | 1997-07-10 |
| US5976546A (en) | 1999-11-02 |
| NZ326092A (en) | 1999-11-29 |
| ES2281087T3 (es) | 2007-09-16 |
| DE69636891D1 (de) | 2007-03-22 |
| EP0870022A1 (en) | 1998-10-14 |
| JP3908277B2 (ja) | 2007-04-25 |
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