DK0871488T3 - Frembringelse af analgetisk synergi ved co-indgivelse af subanalgetiske doser af en mu-opioidagonist og en k2-opioidagonist - Google Patents

Frembringelse af analgetisk synergi ved co-indgivelse af subanalgetiske doser af en mu-opioidagonist og en k2-opioidagonist

Info

Publication number
DK0871488T3
DK0871488T3 DK96933277T DK96933277T DK0871488T3 DK 0871488 T3 DK0871488 T3 DK 0871488T3 DK 96933277 T DK96933277 T DK 96933277T DK 96933277 T DK96933277 T DK 96933277T DK 0871488 T3 DK0871488 T3 DK 0871488T3
Authority
DK
Denmark
Prior art keywords
opioid agonist
analgesic
administering
generating
analgesic synergy
Prior art date
Application number
DK96933277T
Other languages
Danish (da)
English (en)
Inventor
Maree Smith
Fraser Ross
Original Assignee
Univ Queensland
Lynx Project Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Queensland, Lynx Project Ltd filed Critical Univ Queensland
Application granted granted Critical
Publication of DK0871488T3 publication Critical patent/DK0871488T3/da

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445Non condensed piperidines, e.g. piperocaine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47Quinolines; Isoquinolines
    • A61K31/485Morphinan derivatives, e.g. morphine, codeine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Emergency Medicine (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
DK96933277T 1995-10-19 1996-10-21 Frembringelse af analgetisk synergi ved co-indgivelse af subanalgetiske doser af en mu-opioidagonist og en k2-opioidagonist DK0871488T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
AUPN6038A AUPN603895A0 (en) 1995-10-19 1995-10-19 Production of analgesic synergy by co-administration of sub-analgesic doses of two strong opioids
PCT/AU1996/000656 WO1997014438A1 (en) 1995-10-19 1996-10-21 Production of analgesic synergy by co-administration of sub-analgesic doses of a mu opioid agonist and a kappa-2 opioid agonist

Publications (1)

Publication Number Publication Date
DK0871488T3 true DK0871488T3 (da) 2005-08-15

Family

ID=3790365

Family Applications (1)

Application Number Title Priority Date Filing Date
DK96933277T DK0871488T3 (da) 1995-10-19 1996-10-21 Frembringelse af analgetisk synergi ved co-indgivelse af subanalgetiske doser af en mu-opioidagonist og en k2-opioidagonist

Country Status (13)

Country Link
US (1) US6310072B1 (de)
EP (1) EP0871488B1 (de)
JP (1) JP4571236B2 (de)
CN (1) CN1104910C (de)
AT (1) ATE292982T1 (de)
AU (2) AUPN603895A0 (de)
CA (1) CA2235375C (de)
DE (1) DE69634609T2 (de)
DK (1) DK0871488T3 (de)
ES (1) ES2241003T3 (de)
NZ (1) NZ319531A (de)
WO (1) WO1997014438A1 (de)
ZA (1) ZA968808B (de)

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US8202535B2 (en) 2006-01-06 2012-06-19 Acelrx Pharmaceuticals, Inc. Small-volume oral transmucosal dosage forms
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Also Published As

Publication number Publication date
JP2000511158A (ja) 2000-08-29
DE69634609T2 (de) 2006-02-02
DE69634609D1 (de) 2005-05-19
AUPN603895A0 (en) 1995-11-09
ES2241003T3 (es) 2005-10-16
CN1104910C (zh) 2003-04-09
EP0871488A1 (de) 1998-10-21
CA2235375A1 (en) 1997-04-24
NZ319531A (en) 1999-11-29
CA2235375C (en) 2008-01-08
AU7207696A (en) 1997-05-07
AU706691B2 (en) 1999-06-24
US6310072B1 (en) 2001-10-30
EP0871488B1 (de) 2005-04-13
WO1997014438A1 (en) 1997-04-24
JP4571236B2 (ja) 2010-10-27
ATE292982T1 (de) 2005-04-15
CN1204264A (zh) 1999-01-06
EP0871488A4 (de) 2001-04-04
ZA968808B (en) 1997-05-27

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