DK0874841T3 - 1-Benzensulfonylpyrrolidin-derivater som antagonister af bradykinin-receptoren - Google Patents
1-Benzensulfonylpyrrolidin-derivater som antagonister af bradykinin-receptorenInfo
- Publication number
- DK0874841T3 DK0874841T3 DK96943182T DK96943182T DK0874841T3 DK 0874841 T3 DK0874841 T3 DK 0874841T3 DK 96943182 T DK96943182 T DK 96943182T DK 96943182 T DK96943182 T DK 96943182T DK 0874841 T3 DK0874841 T3 DK 0874841T3
- Authority
- DK
- Denmark
- Prior art keywords
- benzenesulfonylpyrrolidine
- antagonists
- derivatives
- bradykinin receptor
- alkyl group
- Prior art date
Links
- DSWRVRWIXRRDLN-UHFFFAOYSA-N 1-(benzenesulfonyl)pyrrolidine Chemical class C=1C=CC=CC=1S(=O)(=O)N1CCCC1 DSWRVRWIXRRDLN-UHFFFAOYSA-N 0.000 title 1
- 102000010183 Bradykinin receptor Human genes 0.000 title 1
- 108050001736 Bradykinin receptor Proteins 0.000 title 1
- 239000005557 antagonist Substances 0.000 title 1
- 125000006273 (C1-C3) alkyl group Chemical group 0.000 abstract 2
- 125000004169 (C1-C6) alkyl group Chemical group 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 229910052736 halogen Inorganic materials 0.000 abstract 1
- 125000005843 halogen group Chemical group 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 230000001225 therapeutic effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR9515706A FR2743073B1 (fr) | 1995-12-29 | 1995-12-29 | Nouveaux composes de 1-benzenesulfonylpyrrolidine, procede de preparation et utilisation en therapeutique |
| PCT/FR1996/002066 WO1997024349A1 (fr) | 1995-12-29 | 1996-12-23 | Derives de 1-benzenesulfonylpyrrolidine comme antagonistes du recepteur de la bradykinine |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK0874841T3 true DK0874841T3 (da) | 2002-01-28 |
Family
ID=9486120
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK96943182T DK0874841T3 (da) | 1995-12-29 | 1996-12-23 | 1-Benzensulfonylpyrrolidin-derivater som antagonister af bradykinin-receptoren |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US6211181B1 (da) |
| EP (1) | EP0874841B1 (da) |
| JP (1) | JP2000502693A (da) |
| AT (1) | ATE206418T1 (da) |
| AU (1) | AU1198897A (da) |
| DE (1) | DE69615707T2 (da) |
| DK (1) | DK0874841T3 (da) |
| ES (1) | ES2167617T3 (da) |
| FR (1) | FR2743073B1 (da) |
| PT (1) | PT874841E (da) |
| WO (1) | WO1997024349A1 (da) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2751650B1 (fr) * | 1996-07-24 | 1998-10-09 | Fournier Ind & Sante | Nouveaux composes de n-benzenesulfonyl-l-proline, procede de preparation et utilisation en therapeutique |
| US6872742B2 (en) | 1996-08-28 | 2005-03-29 | The Procter & Gamble Company | Substituted cyclic amine metalloprotease inhibitors |
| ATE226193T1 (de) | 1996-08-28 | 2002-11-15 | Procter & Gamble | Substituierte zyklische amine als metalloproteaseinhibitoren |
| CA2298617A1 (en) | 1997-07-31 | 1999-02-11 | Yetunde Olabisi Taiwo | Acyclic metalloprotease inhibitors |
| FR2790260B1 (fr) * | 1999-02-26 | 2001-05-04 | Fournier Ind & Sante | Nouveaux composes de n-(benzenesulfonamide), procede de preparation et utilisation en therapeutique |
| BR0008716A (pt) | 1999-03-03 | 2002-09-24 | Procter & Gamble | Inibidores de metaloprotease contendo alquenil ou alquinil |
| AU777735B2 (en) | 1999-07-15 | 2004-10-28 | Pharmacopeia, Inc. | Bradykinin B1 receptor antagonists |
| CA2364178C (en) * | 2000-12-05 | 2006-01-10 | Yasuhiro Katsu | N-benzenesulfonyl l-proline compounds as bradykinin antagonists |
| FR2819254B1 (fr) * | 2001-01-08 | 2003-04-18 | Fournier Lab Sa | Nouveaux composes de la n-(phenylsulfonyl) glycine, leur procede de preparation et leur utilisation pour obtenir des compostions pharmaceutiques |
| EP1914236A1 (en) | 2002-04-10 | 2008-04-23 | Ortho-McNeil Pharmaceutical, Inc. | Novel heteroaryl alkylamide derivatives useful as bradykinin receptor modulators |
| FR2840897B1 (fr) | 2002-06-14 | 2004-09-10 | Fournier Lab Sa | Nouveaux derives d'arylsulfonamides et leur utilisation en therapeutique |
| BRPI0408689B8 (pt) | 2003-03-25 | 2021-05-25 | Laboratoires Fournier S A | derivados de benzenosulfonamida, método para preparação e utilização disso para o tratamento da dor |
| BR112014021498A2 (pt) * | 2012-02-29 | 2017-07-18 | Institute For Hepatitis And Virus Res | composto, composição e método para tratar uma doença associada com formação de dna circular covalentemente fechado |
| WO2016170382A1 (en) | 2015-04-23 | 2016-10-27 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Pharmaceutical compositions comprising a bradykinin 2 receptor antagonist for prevention or treatment of impaired skin wound healing |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3632329A1 (de) | 1986-09-24 | 1988-03-31 | Bayer Ag | Substituierte phenylsulfonamide |
| US5288725A (en) * | 1992-10-15 | 1994-02-22 | Merck & Co., Inc. | Pyrroloquinoline Bradykinin antagonist |
| AU686115B2 (en) | 1992-11-02 | 1998-02-05 | Fujisawa Pharmaceutical Co., Ltd. | Imidazo (I,2-a) pyridine derivatives as bradykinin antagonists, pharmaceuticals and processes for their preparation |
| AU680870B2 (en) * | 1993-04-28 | 1997-08-14 | Astellas Pharma Inc. | New heterocyclic compounds |
-
1995
- 1995-12-29 FR FR9515706A patent/FR2743073B1/fr not_active Expired - Fee Related
-
1996
- 1996-12-23 ES ES96943182T patent/ES2167617T3/es not_active Expired - Lifetime
- 1996-12-23 JP JP09524064A patent/JP2000502693A/ja active Pending
- 1996-12-23 PT PT96943182T patent/PT874841E/pt unknown
- 1996-12-23 EP EP96943182A patent/EP0874841B1/fr not_active Expired - Lifetime
- 1996-12-23 US US09/091,988 patent/US6211181B1/en not_active Expired - Fee Related
- 1996-12-23 AU AU11988/97A patent/AU1198897A/en not_active Abandoned
- 1996-12-23 DK DK96943182T patent/DK0874841T3/da active
- 1996-12-23 AT AT96943182T patent/ATE206418T1/de not_active IP Right Cessation
- 1996-12-23 DE DE69615707T patent/DE69615707T2/de not_active Expired - Fee Related
- 1996-12-23 WO PCT/FR1996/002066 patent/WO1997024349A1/fr not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| DE69615707D1 (de) | 2001-11-08 |
| FR2743073A1 (fr) | 1997-07-04 |
| US6211181B1 (en) | 2001-04-03 |
| ATE206418T1 (de) | 2001-10-15 |
| JP2000502693A (ja) | 2000-03-07 |
| WO1997024349A1 (fr) | 1997-07-10 |
| EP0874841A1 (fr) | 1998-11-04 |
| FR2743073B1 (fr) | 1998-02-20 |
| AU1198897A (en) | 1997-07-28 |
| ES2167617T3 (es) | 2002-05-16 |
| EP0874841B1 (fr) | 2001-10-04 |
| DE69615707T2 (de) | 2002-08-08 |
| PT874841E (pt) | 2002-03-28 |
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