DK0888452T3 - Human CYR61, et ekstracellulært matrix-signalmolekyle - Google Patents
Human CYR61, et ekstracellulært matrix-signalmolekyleInfo
- Publication number
- DK0888452T3 DK0888452T3 DK97916018T DK97916018T DK0888452T3 DK 0888452 T3 DK0888452 T3 DK 0888452T3 DK 97916018 T DK97916018 T DK 97916018T DK 97916018 T DK97916018 T DK 97916018T DK 0888452 T3 DK0888452 T3 DK 0888452T3
- Authority
- DK
- Denmark
- Prior art keywords
- ecm signalling
- signalling molecules
- mammalian ecm
- methods
- mammalian
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/475—Growth factors; Growth regulators
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2217/00—Genetically modified animals
- A01K2217/05—Animals comprising random inserted nucleic acids (transgenic)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2799/00—Uses of viruses
- C12N2799/02—Uses of viruses as vector
- C12N2799/021—Uses of viruses as vector for the expression of a heterologous nucleic acid
- C12N2799/026—Uses of viruses as vector for the expression of a heterologous nucleic acid where the vector is derived from a baculovirus
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- Immunology (AREA)
- Toxicology (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Dermatology (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Physical Education & Sports Medicine (AREA)
- Pulmonology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
- Saccharide Compounds (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Steroid Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US1395896P | 1996-03-15 | 1996-03-15 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK0888452T3 true DK0888452T3 (da) | 2004-06-14 |
Family
ID=21762734
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK97916018T DK0888452T3 (da) | 1996-03-15 | 1997-03-14 | Human CYR61, et ekstracellulært matrix-signalmolekyle |
Country Status (10)
| Country | Link |
|---|---|
| US (3) | US6413735B1 (de) |
| EP (1) | EP0888452B1 (de) |
| JP (1) | JP4307552B2 (de) |
| CN (1) | CN1263852C (de) |
| AT (1) | ATE259419T1 (de) |
| AU (1) | AU733382B2 (de) |
| CA (1) | CA2248549A1 (de) |
| DE (1) | DE69727558T2 (de) |
| DK (1) | DK0888452T3 (de) |
| WO (1) | WO1997033995A2 (de) |
Families Citing this family (68)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7026299B2 (en) | 1994-07-12 | 2006-04-11 | Human Genome Sciences, Inc. | Connective tissue growth factor-2 |
| DK0804562T3 (da) | 1994-07-12 | 2003-02-10 | Human Genome Sciences Inc | Bindevævsvækstfaktor-2 |
| US7521540B2 (en) | 1996-03-15 | 2009-04-21 | Munin Corporation | CYR61 compositions and methods |
| JP4307552B2 (ja) | 1996-03-15 | 2009-08-05 | ミューニン コーポレイション | 細胞外マトリックスシグナリング分子 |
| WO1999033878A1 (en) * | 1997-12-25 | 1999-07-08 | Japan Tobacco Inc. | Monoclonal antibody against connective tissue growth factor and medicinal uses thereof |
| AUPP249298A0 (en) * | 1998-03-20 | 1998-04-23 | Ag-Gene Australia Limited | Synthetic genes and genetic constructs comprising same I |
| WO1999049029A1 (en) * | 1998-03-20 | 1999-09-30 | Benitec Australia Ltd | Control of gene expression |
| AU5301499A (en) | 1998-08-20 | 2000-03-14 | Chugai Seiyaku Kabushiki Kaisha | Method for screening candidate compounds for drug against tumor |
| KR100821644B1 (ko) | 1999-07-14 | 2008-04-11 | 노보 노르디스크 헬스 케어 악티엔게젤샤프트 | 유전자 발현 및 세포 이동 또는 주화성을 조절하기 위한FVIIa 또는 조직 인자 길항제의 사용 |
| US6423885B1 (en) * | 1999-08-13 | 2002-07-23 | Commonwealth Scientific And Industrial Research Organization (Csiro) | Methods for obtaining modified phenotypes in plant cells |
| DK1254169T3 (da) * | 1999-12-30 | 2007-08-06 | Harvard College | Fremgangsmåde vedrörende modulering af aktivitet af Th2-celledelmængde ved modulering af aktivitet af XBP-1 |
| EP1892250A3 (de) * | 2000-01-31 | 2008-09-17 | Munin Corporation | CYR61-Zusammensetzungen und Verfahren |
| CA2398660A1 (en) * | 2000-01-31 | 2001-08-02 | Munin Corporation | Human cyr61 |
| AU2001245734A1 (en) * | 2000-03-15 | 2001-09-24 | Orbus Medical Technologies Inc. | Coating that promotes endothelial cell adherence |
| US8088060B2 (en) | 2000-03-15 | 2012-01-03 | Orbusneich Medical, Inc. | Progenitor endothelial cell capturing with a drug eluting implantable medical device |
| US8460367B2 (en) | 2000-03-15 | 2013-06-11 | Orbusneich Medical, Inc. | Progenitor endothelial cell capturing with a drug eluting implantable medical device |
| US9522217B2 (en) | 2000-03-15 | 2016-12-20 | Orbusneich Medical, Inc. | Medical device with coating for capturing genetically-altered cells and methods for using same |
| WO2001098359A2 (en) * | 2000-06-21 | 2001-12-27 | Wyeth | Cyr61 as a target for treatment and diagnosis of breast cancer |
| WO2002004480A2 (en) * | 2000-07-11 | 2002-01-17 | Human Genome Sciences, Inc. | Connective tissue growth factor-2 |
| EP1313697B1 (de) | 2000-08-29 | 2005-11-30 | Nobex Corporation | Immunoregulierende verbindungen, deren derivate und ihre verwendung |
| JP2005508133A (ja) | 2001-01-11 | 2005-03-31 | キュラジェン コーポレイション | タンパク質およびそれをコードする核酸 |
| US8048924B2 (en) | 2001-08-29 | 2011-11-01 | Biocon Limited | Methods and compositions employing 4-aminophenylacetic acid compounds |
| US7592175B2 (en) | 2002-12-16 | 2009-09-22 | Technion Research & Development Foundation Ltd. | Methods of preparing feeder cells-free, xeno-free human embryonic stem cells and cell cultures prepared using same |
| EP1608970A4 (de) * | 2003-03-31 | 2006-06-14 | Munin Corp | Ccn3-zusammensetzungen und verfahren |
| JP2004315480A (ja) * | 2003-04-21 | 2004-11-11 | Yoshiyuki Kakehi | 前立腺疾患治療用医薬組成物 |
| TWI356097B (en) * | 2003-06-20 | 2012-01-11 | Munin Corp | Ccn1 compositions and methods |
| US8491883B2 (en) | 2003-06-27 | 2013-07-23 | Advanced Technologies And Regenerative Medicine, Llc | Treatment of amyotrophic lateral sclerosis using umbilical derived cells |
| US9572840B2 (en) | 2003-06-27 | 2017-02-21 | DePuy Synthes Products, Inc. | Regeneration and repair of neural tissue using postpartum-derived cells |
| CA2530732C (en) | 2003-06-27 | 2015-03-31 | DePuy Synthes Products, Inc. | Regeneration and repair of neural tissue using postpartum-derived cells |
| US7875272B2 (en) | 2003-06-27 | 2011-01-25 | Ethicon, Incorporated | Treatment of stroke and other acute neuraldegenerative disorders using postpartum derived cells |
| US8518390B2 (en) | 2003-06-27 | 2013-08-27 | Advanced Technologies And Regenerative Medicine, Llc | Treatment of stroke and other acute neural degenerative disorders via intranasal administration of umbilical cord-derived cells |
| US9592258B2 (en) | 2003-06-27 | 2017-03-14 | DePuy Synthes Products, Inc. | Treatment of neurological injury by administration of human umbilical cord tissue-derived cells |
| US8790637B2 (en) | 2003-06-27 | 2014-07-29 | DePuy Synthes Products, LLC | Repair and regeneration of ocular tissue using postpartum-derived cells |
| US20050177885A1 (en) * | 2004-02-09 | 2005-08-11 | Lau Lester F. | CCN1 transgenic animals |
| EP1773767B1 (de) | 2004-07-07 | 2016-03-09 | Biocon Limited | Synthese von azogebundenen, das immunsystem regulierenden verbindungen |
| WO2006071802A2 (en) | 2004-12-23 | 2006-07-06 | Ethicon Incorporated | Treatment of stroke and other acute neural degenerative disorders using postpartum derived cells |
| CA2589041C (en) * | 2004-12-23 | 2019-08-20 | DePuy Synthes Products, Inc. | Postpartum cells derived from umbilical cord tissue, and methods of making and using the same |
| US20070037186A1 (en) | 2005-05-20 | 2007-02-15 | Yuqiu Jiang | Thyroid fine needle aspiration molecular assay |
| EP3354723B1 (de) | 2005-08-29 | 2023-12-13 | Technion Research & Development Foundation Ltd. | Medien zur züchtung von stammzellen |
| JP5289970B2 (ja) | 2005-12-16 | 2013-09-11 | エシコン・インコーポレイテッド | 組織適合性不適合な移植における逆免疫反応を抑制するための組成物および方法 |
| AU2006327073B2 (en) | 2005-12-19 | 2012-08-30 | Ethicon, Inc. | In vitro expansion of postpartum derived cells in roller bottles |
| US9125906B2 (en) | 2005-12-28 | 2015-09-08 | DePuy Synthes Products, Inc. | Treatment of peripheral vascular disease using umbilical cord tissue-derived cells |
| EP3441459B1 (de) | 2006-08-02 | 2021-03-17 | Technion Research & Development Foundation Limited | Verfahren zur expansion embryonaler stammzellen in einer suspensionskultur |
| UA99152C2 (ru) | 2007-10-05 | 2012-07-25 | Этикон, Инкорпорейтед | Восстановление и регенерация почечной ткани с использованием клеток, полученных с человеческой ткани пупочного канатика |
| US8236538B2 (en) | 2007-12-20 | 2012-08-07 | Advanced Technologies And Regenerative Medicine, Llc | Methods for sterilizing materials containing biologically active agents |
| UA99167C2 (ru) * | 2007-12-27 | 2012-07-25 | Этикон, Инкорпорейтед | Лечение дегенерации межреберных дисков с использованием клеток, полученных из ткани пуповины человека |
| US8940479B2 (en) * | 2008-01-14 | 2015-01-27 | Cornell University | Methods for modulating de novo hepatic lipogenesis by modulating XBP-1 activity |
| CN101747435B (zh) * | 2008-12-18 | 2013-06-19 | 上海市免疫学研究所 | 一种中和cyr61的单克隆抗体(杂交瘤)及其应用 |
| BRPI0923068B1 (pt) | 2008-12-19 | 2021-05-25 | Advanced Technologies And Regenerative Medicine, Llc | Uso de células derivadas de tecido de cordão umbilical para tratar um paciente tendo uma doença, distúrbio ou injúria pulmonar |
| US10179900B2 (en) | 2008-12-19 | 2019-01-15 | DePuy Synthes Products, Inc. | Conditioned media and methods of making a conditioned media |
| ES2629003T3 (es) | 2009-03-26 | 2017-08-07 | DePuy Synthes Products, Inc. | Células de tejido de cordón umbilical humano como tratamiento para la enfermedad de alzheimer |
| TW201102086A (en) | 2009-06-04 | 2011-01-16 | Hoffmann La Roche | Antibodies against human CCN1 and uses thereof |
| ES2932664T3 (es) | 2009-11-12 | 2023-01-23 | Technion Res & Dev Foundation | Medios de cultivo, cultivos celulares y métodos de cultivo de células madre pluripotentes en estado no diferenciado |
| EP2540742A4 (de) * | 2009-12-04 | 2014-02-12 | Shanghai Inst Of Immunology | Monoklonale antikörper gegen das protein cyr61 und anwendungen davon |
| DE102010010288A1 (de) | 2010-03-04 | 2011-09-08 | Wolfgang Poller | CCN1 zur Prävention und Therapie von entzündlichen Erkrankungen |
| WO2011107590A1 (en) | 2010-03-04 | 2011-09-09 | Wolfgang Poller | Cnn1 (cyr61) for prevention and therapy of inflammatory disease |
| EP2649445B1 (de) | 2010-12-06 | 2015-05-06 | THD S.p.A. | Verfahren zur diagnose eines karzinoms |
| WO2012109238A2 (en) | 2011-02-07 | 2012-08-16 | President And Fellows Of Harvard College | Methods for increasing immune responses using agents that directly bind to and activate ire-1 |
| AU2012358810B2 (en) | 2011-12-23 | 2018-03-15 | DePuy Synthes Products, Inc. | Detection of human umbilical cord tissue-derived cells |
| US20150018406A1 (en) | 2012-03-09 | 2015-01-15 | Cornell University | Modulation of breast cancer growth by modulation of xbp1 activity |
| WO2014165999A1 (en) | 2013-04-12 | 2014-10-16 | The Royal Institution For The Advancement Of Learning/Mcgill University | Therapeutic viral microparticles for promoting stent biofunctionality and wound healing in vertebrate individuals |
| WO2015013875A1 (zh) * | 2013-07-30 | 2015-02-05 | 杭州微基质生物科技有限公司 | 一种全能干细胞培养方法 |
| EP3521431A1 (de) | 2013-09-25 | 2019-08-07 | Cornell University | Verbindungen zur induzierung von antitumorimmunität und verfahren dafür |
| CN105396136B (zh) * | 2015-11-23 | 2018-10-30 | 上海交通大学医学院附属第九人民医院 | CCN1(Cyr61)在治疗皮肤损伤及皮肤萎缩相关疾病中的应用 |
| US10767164B2 (en) | 2017-03-30 | 2020-09-08 | The Research Foundation For The State University Of New York | Microenvironments for self-assembly of islet organoids from stem cells differentiation |
| US12331320B2 (en) | 2018-10-10 | 2025-06-17 | The Research Foundation For The State University Of New York | Genome edited cancer cell vaccines |
| CN110938128B (zh) * | 2019-11-08 | 2021-07-13 | 上海交通大学 | 一种生物活性多肽pkcpkcdkevyfaervtsl及其制备方法和应用 |
| CH716377B1 (it) * | 2020-08-05 | 2020-12-30 | Contrad Swiss Sa | Idrogel ad applicazione topica efficace nel prevenire e/o attenuare la degenerazione della cartilagine. |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4554101A (en) | 1981-01-09 | 1985-11-19 | New York Blood Center, Inc. | Identification and preparation of epitopes on antigens and allergens on the basis of hydrophilicity |
| JPH05255397A (ja) | 1991-01-18 | 1993-10-05 | Bristol Myers Squibb Co | TGF−β誘導遺伝子系統群 |
| US5770209A (en) | 1991-08-30 | 1998-06-23 | University Of South Florida | Acceleration of wound healing using connective tissue growth factor |
| US5408040A (en) | 1991-08-30 | 1995-04-18 | University Of South Florida | Connective tissue growth factor(CTGF) |
| US5565332A (en) * | 1991-09-23 | 1996-10-15 | Medical Research Council | Production of chimeric antibodies - a combinatorial approach |
| US5817310A (en) * | 1991-12-02 | 1998-10-06 | Cor Therapeutics, Inc. | Inhibitory immunoglobulin polypeptides to human PDGF beta receptor |
| DK0804562T3 (da) | 1994-07-12 | 2003-02-10 | Human Genome Sciences Inc | Bindevævsvækstfaktor-2 |
| JP4307552B2 (ja) | 1996-03-15 | 2009-08-05 | ミューニン コーポレイション | 細胞外マトリックスシグナリング分子 |
| EP0907719A4 (de) | 1996-03-20 | 2003-02-19 | Human Genome Sciences Inc | Menschliches zytokinpolypeptid |
-
1997
- 1997-03-14 JP JP53289897A patent/JP4307552B2/ja not_active Expired - Lifetime
- 1997-03-14 AU AU23296/97A patent/AU733382B2/en not_active Expired
- 1997-03-14 CA CA002248549A patent/CA2248549A1/en not_active Abandoned
- 1997-03-14 DE DE69727558T patent/DE69727558T2/de not_active Expired - Lifetime
- 1997-03-14 CN CNB971946094A patent/CN1263852C/zh not_active Expired - Fee Related
- 1997-03-14 DK DK97916018T patent/DK0888452T3/da active
- 1997-03-14 WO PCT/US1997/004193 patent/WO1997033995A2/en not_active Ceased
- 1997-03-14 EP EP97916018A patent/EP0888452B1/de not_active Expired - Lifetime
- 1997-03-14 AT AT97916018T patent/ATE259419T1/de not_active IP Right Cessation
- 1997-03-14 US US09/142,569 patent/US6413735B1/en not_active Expired - Fee Related
-
2002
- 2002-01-22 US US10/053,753 patent/US7064185B2/en not_active Expired - Fee Related
-
2006
- 2006-06-19 US US11/455,506 patent/US20060257965A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| EP0888452B1 (de) | 2004-02-11 |
| CN1263852C (zh) | 2006-07-12 |
| DE69727558T2 (de) | 2004-12-16 |
| US7064185B2 (en) | 2006-06-20 |
| AU2329697A (en) | 1997-10-01 |
| WO1997033995A2 (en) | 1997-09-18 |
| CN1222193A (zh) | 1999-07-07 |
| WO1997033995A3 (en) | 1998-01-08 |
| US20060257965A1 (en) | 2006-11-16 |
| US6413735B1 (en) | 2002-07-02 |
| EP0888452A2 (de) | 1999-01-07 |
| US20020150986A1 (en) | 2002-10-17 |
| JP4307552B2 (ja) | 2009-08-05 |
| AU733382B2 (en) | 2001-05-10 |
| JP2000506732A (ja) | 2000-06-06 |
| HK1018707A1 (en) | 2000-01-04 |
| DE69727558D1 (de) | 2004-03-18 |
| CA2248549A1 (en) | 1997-09-18 |
| ATE259419T1 (de) | 2004-02-15 |
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