BR9608558A - Processos e usos de fator de crescimento de tecido conjuntivo como um agente de indução - Google Patents

Processos e usos de fator de crescimento de tecido conjuntivo como um agente de indução

Info

Publication number
BR9608558A
BR9608558A BR9608558-4A BR9608558A BR9608558A BR 9608558 A BR9608558 A BR 9608558A BR 9608558 A BR9608558 A BR 9608558A BR 9608558 A BR9608558 A BR 9608558A
Authority
BR
Brazil
Prior art keywords
ctgf
growth factor
connective tissue
tissue growth
inducing agent
Prior art date
Application number
BR9608558-4A
Other languages
English (en)
Inventor
Gary R Grotendorst
Original Assignee
Gary R Grotendorst
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Gary R Grotendorst filed Critical Gary R Grotendorst
Publication of BR9608558A publication Critical patent/BR9608558A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475—Growth factors; Growth regulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/18—Growth factors; Growth regulators
    • A61K38/1841—Transforming growth factor [TGF]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/39—Connective tissue peptides, e.g. collagen, elastin, laminin, fibronectin, vitronectin, cold insoluble globulin [CIG]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/04—Drugs for skeletal disorders for non-specific disorders of the connective tissue
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/06—Antiglaucoma agents or miotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
    • C12N5/0655—Chondrocytes; Cartilage
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Zoology (AREA)
  • Biomedical Technology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Wood Science & Technology (AREA)
  • Rheumatology (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Epidemiology (AREA)
  • Cell Biology (AREA)
  • Microbiology (AREA)
  • Urology & Nephrology (AREA)
  • Toxicology (AREA)
  • General Engineering & Computer Science (AREA)
  • Ophthalmology & Optometry (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Pulmonology (AREA)
  • Dermatology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Vascular Medicine (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)

Abstract

Patente de Invenção: <B>"PROCESSOS E USOS DE FATOR DE CRESCIMENTO DE TECIDO CONJUNTIVO COMO UM AGENTE DE INDUçãO"<D>. A presente invenção refere-se a novos processos e composições relacionados à administração de fator de crescimento de tecido conjuntivo, sozinho ou em combinação com outros fatores de crescimento, composições ou compostos, para induzir a formação de tecido conjuntivo, incluindo osso, cartilagem e a pele.
BR9608558-4A 1995-06-02 1996-05-31 Processos e usos de fator de crescimento de tecido conjuntivo como um agente de indução BR9608558A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/459,717 US5770209A (en) 1991-08-30 1995-06-02 Acceleration of wound healing using connective tissue growth factor
PCT/US1996/008210 WO1996038168A1 (en) 1995-06-02 1996-05-31 Methods and uses of connective tissue growth factor as an induction agent

Publications (1)

Publication Number Publication Date
BR9608558A true BR9608558A (pt) 1999-11-30

Family

ID=23825885

Family Applications (2)

Application Number Title Priority Date Filing Date
BR9609521A BR9609521A (pt) 1995-06-02 1996-05-31 Fator de crescimento de tecido conectivo
BR9608558-4A BR9608558A (pt) 1995-06-02 1996-05-31 Processos e usos de fator de crescimento de tecido conjuntivo como um agente de indução

Family Applications Before (1)

Application Number Title Priority Date Filing Date
BR9609521A BR9609521A (pt) 1995-06-02 1996-05-31 Fator de crescimento de tecido conectivo

Country Status (11)

Country Link
US (4) US5770209A (pt)
EP (2) EP0831885A4 (pt)
JP (4) JPH11506449A (pt)
CN (2) CN1191491A (pt)
AT (1) ATE464067T1 (pt)
AU (2) AU722919B2 (pt)
BR (2) BR9609521A (pt)
CA (2) CA2222509C (pt)
DE (1) DE69638162D1 (pt)
SG (1) SG108208A1 (pt)
WO (2) WO1996038168A1 (pt)

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US7026299B2 (en) 1994-07-12 2006-04-11 Human Genome Sciences, Inc. Connective tissue growth factor-2
US6638912B2 (en) 1995-05-01 2003-10-28 The Regents Of The University Of California Peptide compositions mimicking TGF-β activity
AU763649B2 (en) * 1995-06-02 2003-07-31 University Of South Florida Connective tissue growth factor
US6790606B1 (en) 1996-03-15 2004-09-14 Munin Corporation Extracellular matrix signaling molecules
US7521540B2 (en) * 1996-03-15 2009-04-21 Munin Corporation CYR61 compositions and methods
US20090081228A1 (en) * 1996-03-15 2009-03-26 Munin Corporation Cyr61 compositions and methods
CN1263852C (zh) 1996-03-15 2006-07-12 穆尼恩公司 胞外基质信号分子
CA2270908A1 (en) * 1996-11-08 1998-05-22 Human Genome Sciences, Inc. Connective tissue growth factor-3
US20040132987A1 (en) 1996-11-08 2004-07-08 Human Genome Sciences, Inc. Connective tissue growth factor-3
JP4531135B2 (ja) * 1996-12-06 2010-08-25 オシリス セラピューティクス，インコーポレイテッド ヒト間葉幹細胞の改良された軟骨形成分化
DE19719652A1 (de) * 1997-05-09 1998-12-03 Merckle Gmbh Tissue-Faktor zur Förderung von Wundheilung
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US6797289B2 (en) * 1998-02-13 2004-09-28 Nutramax Laboratories, Inc. Use of anabolic agents, anti-catabolic agents, antioxidant agents, and analgesics for protection, treatment and repair of connective tissues in humans and animals
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US7115390B1 (en) 1998-12-14 2006-10-03 Fibrogen, Inc. Connective tissue growth factor fragments and methods and uses thereof
US6350472B1 (en) * 1998-12-14 2002-02-26 Steinbach, Pylant, And Hermann, L.L.C. Method of treating HIV infection with transdermal gel containing mammalian liver extract
KR100704537B1 (ko) * 1999-02-01 2007-04-09 제네틱스 인스티튜트, 엘엘씨 관절 연골의 치유 및 회복을 위한 조성물
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Also Published As

Publication number Publication date
WO1996038172A1 (en) 1996-12-05
CN1191491A (zh) 1998-08-26
US5770209A (en) 1998-06-23
CA2222509C (en) 2012-12-04
EP0831885A4 (en) 2000-11-29
EP0831903B1 (en) 2010-04-14
AU5885596A (en) 1996-12-18
JPH11507332A (ja) 1999-06-29
JP2007051150A (ja) 2007-03-01
JP2004132974A (ja) 2004-04-30
EP0831885A1 (en) 1998-04-01
ATE464067T1 (de) 2010-04-15
BR9609521A (pt) 1999-06-15
AU5958296A (en) 1996-12-18
MX9709294A (es) 1998-08-30
WO1996038168A1 (en) 1996-12-05
DE69638162D1 (de) 2010-05-27
AU720268B2 (en) 2000-05-25
US6069006A (en) 2000-05-30
CA2222509A1 (en) 1996-12-05
US6232064B1 (en) 2001-05-15
EP0831903A4 (en) 2001-02-28
AU722919B2 (en) 2000-08-17
JPH11506449A (ja) 1999-06-08
CN1195295A (zh) 1998-10-07
SG108208A1 (en) 2005-01-28
EP0831903A1 (en) 1998-04-01
US6150101A (en) 2000-11-21
CA2222609A1 (en) 1996-12-05

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