DK0891345T3 - Nye diarylmethylidenfuranderivater, fremgangsmåder til deres fremstilling og terapeutiske anvendelser deraf - Google Patents

Nye diarylmethylidenfuranderivater, fremgangsmåder til deres fremstilling og terapeutiske anvendelser deraf

Info

Publication number: DK0891345T3
Authority: DK; Denmark
Prior art keywords: methylidene; preparation; methods; therapeutic uses; furan derivatives
Prior art date: 1996-04-04

Application number

DK97919476T

Other languages

English (en)

Inventor

Eric Nicolai

Jean-Marie Teulon

Original Assignee

Union Pharma Scient Appl

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1996-04-04

Filing date

1997-04-03

Publication date

2001-12-03

1997-04-03 Application filed by Union Pharma Scient Appl filed Critical Union Pharma Scient Appl

2001-12-03 Application granted granted Critical

2001-12-03 Publication of DK0891345T3 publication Critical patent/DK0891345T3/da

Links

-1 diaryl methylidene furan derivatives Chemical class 0.000 title 1
230000001225 therapeutic effect Effects 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/06—Antiabortive agents; Labour repressants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
- C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D307/56—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D307/58—One oxygen atom, e.g. butenolide
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Reproductive Health (AREA)
Endocrinology (AREA)
Pain & Pain Management (AREA)
Gynecology & Obstetrics (AREA)
Rheumatology (AREA)
Pregnancy & Childbirth (AREA)
Psychiatry (AREA)
Hospice & Palliative Care (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Furan Compounds (AREA)
Heterocyclic Compounds Containing Sulfur Atoms (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)

DK97919476T 1996-04-04 1997-04-03 Nye diarylmethylidenfuranderivater, fremgangsmåder til deres fremstilling og terapeutiske anvendelser deraf DK0891345T3 (da)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
FR9604236A FR2747123B1 (fr)	1996-04-04	1996-04-04	Nouveaux derives diarylmethylidene tetrahydrofurane, leurs procedes de preparation, et leurs utilisations en therapeutique
FR9607922A FR2747124B1 (fr)	1996-04-04	1996-06-26	Nouveaux derives diarylmethylidene furaniques, leurs procedes de preparation et leurs utilisations en therapeutique
PCT/FR1997/000602 WO1997037984A1 (fr)	1996-04-04	1997-04-03	Nouveaux derives diarylmethylidene furaniques, leurs procedes de preparation et leurs utilisations en therapeutique

Publications (1)

Publication Number	Publication Date
DK0891345T3 true DK0891345T3 (da)	2001-12-03

Family

ID=9490907

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK97919476T DK0891345T3 (da)	1996-04-04	1997-04-03	Nye diarylmethylidenfuranderivater, fremgangsmåder til deres fremstilling og terapeutiske anvendelser deraf

Country Status (28)

Country	Link
EP (1)	EP0891345B1 (da)
JP (1)	JP2000508638A (da)
KR (1)	KR20000005146A (da)
CN (1)	CN1215396A (da)
AR (1)	AR006539A1 (da)
AT (1)	ATE204268T1 (da)
AU (1)	AU717146B2 (da)
BG (1)	BG62808B1 (da)
BR (1)	BR9708510A (da)
CA (1)	CA2248949A1 (da)
CZ (1)	CZ318898A3 (da)
DE (1)	DE69706157T2 (da)
DK (1)	DK0891345T3 (da)
EE (1)	EE03687B1 (da)
ES (1)	ES2162678T3 (da)
FR (2)	FR2747123B1 (da)
GE (1)	GEP20032924B (da)
IL (1)	IL126105A (da)
NO (1)	NO984624L (da)
NZ (1)	NZ331672A (da)
PL (1)	PL329213A1 (da)
PT (1)	PT891345E (da)
RU (1)	RU2189979C2 (da)
SI (1)	SI0891345T1 (da)
SK (1)	SK283292B6 (da)
TW (1)	TW353660B (da)
WO (1)	WO1997037984A1 (da)
ZA (1)	ZA972894B (da)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US6180651B1 (en) *	1996-04-04	2001-01-30	Bristol-Myers Squibb	Diarylmethylidenefuran derivatives, processes for their preparation and their uses in therapeutics
US6026814A (en)	1997-03-06	2000-02-22	Scimed Life Systems, Inc.	System and method for percutaneous coronary artery bypass
JP2001518087A (ja) *	1997-04-02	2001-10-09	メルクフロストカナダアンドカンパニー	選択的シクロオキシゲナーゼ−２阻害薬としてのα−メチレン−γ−ラクトン類
FR2775477B1 (fr) *	1998-02-27	2000-05-19	Union Pharma Scient Appl	Nouveaux derives diarylmethylene heterocycliques, leurs procedes de preparation et leurs utilisations en therapeutique
CN1106392C (zh) *	2000-10-24	2003-04-23	中国科学院上海有机化学研究所	一种β位不含取代基的丁烯酸内酯及其合成的方法
AR038957A1 (es)	2001-08-15	2005-02-02	Pharmacia Corp	Terapia de combinacion para el tratamiento del cancer
WO2004041217A2 (en) *	2002-11-05	2004-05-21	Magnachem International Laboratories, Inc.	Synthetic lactone formulations and method of use
ATE515493T1 (de) *	2003-03-31	2011-07-15	Council Scient Ind Res	Mercaptophenylnaphthylmethan-derivate und deren herstellung
PT1534305E (pt)	2003-05-07	2007-02-28	Osteologix As	Tratamento de afecções cartilagineas / osseas com sais de estroncio hidrosoluveis
US8779168B2 (en) *	2010-12-16	2014-07-15	Transitions Optical, Inc.	Lactone compounds and materials made therefrom
IL305573A (en)	2021-03-15	2023-10-01	Saul Yedgar	HYALURONIC ACID-CONJUGATED DIPALMITOYL PHOSPHATIDYL ETHANOLAMINE IN COMBINATION WITH NON-STEROIDAL ANTI-INFLAMMATORY DRUGS (NSAIDs) FOR TREATING OR ALLEVIATING INFLAMMATORY DISEASES

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
AU6027694A (en) *	1993-01-15	1994-08-15	G.D. Searle & Co.	Novel 3,4-diaryl thiophenes and analogs thereof having use as antiinflammatory agents
US5474995A (en) *	1993-06-24	1995-12-12	Merck Frosst Canada, Inc.	Phenyl heterocycles as cox-2 inhibitors
IL112249A (en) *	1994-01-25	2001-11-25	Warner Lambert Co	Pharmaceutical compositions containing di and tricyclic pyrimidine derivatives for inhibiting tyrosine kinases of the epidermal growth factor receptor family and some new such compounds
US5585504A (en) *	1994-09-16	1996-12-17	Merck & Co., Inc.	Process of making cox-2 inhibitors having a lactone bridge

1996
- 1996-04-04 FR FR9604236A patent/FR2747123B1/fr not_active Expired - Fee Related
- 1996-06-26 FR FR9607922A patent/FR2747124B1/fr not_active Expired - Lifetime
1997
- 1997-03-24 TW TW086103701A patent/TW353660B/zh active
- 1997-04-03 SI SI9730222T patent/SI0891345T1/xx unknown
- 1997-04-03 IL IL12610597A patent/IL126105A/xx not_active IP Right Cessation
- 1997-04-03 PL PL97329213A patent/PL329213A1/xx unknown
- 1997-04-03 ES ES97919476T patent/ES2162678T3/es not_active Expired - Lifetime
- 1997-04-03 SK SK1375-98A patent/SK283292B6/sk not_active IP Right Cessation
- 1997-04-03 GE GEAP19974555A patent/GEP20032924B/en unknown
- 1997-04-03 NZ NZ331672A patent/NZ331672A/en unknown
- 1997-04-03 CZ CZ983188A patent/CZ318898A3/cs unknown
- 1997-04-03 BR BR9708510A patent/BR9708510A/pt not_active IP Right Cessation
- 1997-04-03 AU AU23933/97A patent/AU717146B2/en not_active Ceased
- 1997-04-03 CN CN97193543A patent/CN1215396A/zh active Pending
- 1997-04-03 EE EE9800333A patent/EE03687B1/xx unknown
- 1997-04-03 RU RU98119887/04A patent/RU2189979C2/ru not_active IP Right Cessation
- 1997-04-03 JP JP9535910A patent/JP2000508638A/ja active Pending
- 1997-04-03 WO PCT/FR1997/000602 patent/WO1997037984A1/fr not_active Ceased
- 1997-04-03 PT PT97919476T patent/PT891345E/pt unknown
- 1997-04-03 EP EP97919476A patent/EP0891345B1/fr not_active Expired - Lifetime
- 1997-04-03 KR KR1019980707808A patent/KR20000005146A/ko not_active Ceased
- 1997-04-03 CA CA002248949A patent/CA2248949A1/fr not_active Abandoned
- 1997-04-03 DK DK97919476T patent/DK0891345T3/da active
- 1997-04-03 AT AT97919476T patent/ATE204268T1/de active
- 1997-04-03 DE DE69706157T patent/DE69706157T2/de not_active Expired - Lifetime
- 1997-04-04 AR ARP970101359A patent/AR006539A1/es not_active Application Discontinuation
- 1997-04-04 ZA ZA9702894A patent/ZA972894B/xx unknown
1998
- 1998-09-16 BG BG102771A patent/BG62808B1/bg unknown
- 1998-10-02 NO NO984624A patent/NO984624L/no not_active Application Discontinuation

Also Published As

Publication number	Publication date
EP0891345B1 (fr)	2001-08-16
PT891345E (pt)	2002-02-28
SK283292B6 (sk)	2003-05-02
AU2393397A (en)	1997-10-29
AR006539A1 (es)	1999-09-08
CN1215396A (zh)	1999-04-28
SK137598A3 (en)	1999-02-11
ZA972894B (en)	1997-11-04
FR2747123B1 (fr)	1998-06-26
EP0891345A1 (fr)	1999-01-20
NO984624L (no)	1998-11-30
SI0891345T1 (en)	2002-02-28
EE03687B1 (et)	2002-04-15
FR2747124B1 (fr)	1998-06-26
CZ318898A3 (cs)	1999-01-13
NZ331672A (en)	2000-02-28
IL126105A0 (en)	1999-05-09
AU717146B2 (en)	2000-03-16
DE69706157D1 (de)	2001-09-20
NO984624D0 (no)	1998-10-02
ES2162678T3 (es)	2002-01-01
BR9708510A (pt)	1999-08-03
PL329213A1 (en)	1999-03-15
ATE204268T1 (de)	2001-09-15
RU2189979C2 (ru)	2002-09-27
WO1997037984A1 (fr)	1997-10-16
KR20000005146A (ko)	2000-01-25
BG102771A (en)	1999-06-30
FR2747124A1 (fr)	1997-10-10
GEP20032924B (en)	2003-03-25
BG62808B1 (bg)	2000-08-31
EE9800333A (et)	1999-04-15
FR2747123A1 (fr)	1997-10-10
TW353660B (en)	1999-03-01
DE69706157T2 (de)	2002-04-11
CA2248949A1 (fr)	1997-10-16
JP2000508638A (ja)	2000-07-11
IL126105A (en)	2001-08-26

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