DK0900227T3 - Forbedret fremgangsmåde til fremstilling af diestere af 2,5-dioxo-4,4-diphenyl-imidazolidin-1-ylmethylphosphorsyre - Google Patents

Forbedret fremgangsmåde til fremstilling af diestere af 2,5-dioxo-4,4-diphenyl-imidazolidin-1-ylmethylphosphorsyre

Info

Publication number: DK0900227T3
Authority: DK; Denmark
Prior art keywords: diphenyl; imidazolidin; dioxo; preparation; pct
Prior art date: 1996-04-30

Application number

DK97917765T

Other languages

English (en)

Inventor

Edward Mark Davis

James E Ellis

David A Katonak

Original Assignee

Warner Lambert Co

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1996-04-30

Filing date

1997-04-01

Publication date

2002-04-08

1997-04-01 Application filed by Warner Lambert Co filed Critical Warner Lambert Co

2002-04-08 Application granted granted Critical

2002-04-08 Publication of DK0900227T3 publication Critical patent/DK0900227T3/da

Links

XWLUWCNOOVRFPX-UHFFFAOYSA-N Fosphenytoin Chemical compound O=C1N(COP(O)(=O)O)C(=O)NC1(C=1C=CC=CC=1)C1=CC=CC=C1 XWLUWCNOOVRFPX-UHFFFAOYSA-N 0.000 title abstract 2
150000005690 diesters Chemical class 0.000 title abstract 2
BFJBNDXKTSJDJN-UHFFFAOYSA-N 3-(bromomethyl)-5,5-diphenylimidazolidine-2,4-dione Chemical compound O=C1N(CBr)C(=O)NC1(C=1C=CC=CC=1)C1=CC=CC=C1 BFJBNDXKTSJDJN-UHFFFAOYSA-N 0.000 abstract 1
229910000318 alkali metal phosphate Inorganic materials 0.000 abstract 1
239000000543 intermediate Substances 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/645—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having two nitrogen atoms as the only ring hetero atoms
- C07F9/6503—Five-membered rings
- C07F9/6506—Five-membered rings having the nitrogen atoms in positions 1 and 3

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Biochemistry (AREA)
General Health & Medical Sciences (AREA)
Molecular Biology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Saccharide Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Indole Compounds (AREA)

DK97917765T 1996-04-30 1997-04-01 Forbedret fremgangsmåde til fremstilling af diestere af 2,5-dioxo-4,4-diphenyl-imidazolidin-1-ylmethylphosphorsyre DK0900227T3 (da)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US1651596P	1996-04-30	1996-04-30
PCT/US1997/005307 WO1997041132A1 (en)	1996-04-30	1997-04-01	Improved process for the synthesis of diesters of phosphoric acid 2,5-dioxo-4,4-diphenyl-imidazolidin-1-ylmethyl ester

Publications (1)

Publication Number	Publication Date
DK0900227T3 true DK0900227T3 (da)	2002-04-08

Family

ID=21777523

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK97917765T DK0900227T3 (da)	1996-04-30	1997-04-01	Forbedret fremgangsmåde til fremstilling af diestere af 2,5-dioxo-4,4-diphenyl-imidazolidin-1-ylmethylphosphorsyre

Country Status (15)

Country	Link
US (2)	US6022975A (da)
EP (1)	EP0900227B1 (da)
JP (1)	JP4035642B2 (da)
KR (1)	KR100453867B1 (da)
AT (1)	ATE210670T1 (da)
AU (1)	AU708127B2 (da)
BR (1)	BR9709198B1 (da)
DE (1)	DE69709091T2 (da)
DK (1)	DK0900227T3 (da)
ES (1)	ES2169375T3 (da)
NZ (1)	NZ332115A (da)
PT (1)	PT900227E (da)
SI (1)	SI0900227T1 (da)
WO (1)	WO1997041132A1 (da)
ZA (1)	ZA973713B (da)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
ES2169375T3 (es)	1996-04-30	2002-07-01	Warner Lambert Co	Proceso mejorado para la sintesis de diesteres del ester 2,5-dioxo-4,4-difenil-imidazolidin-1-ilmetilico de acido fosforico.
US20070219378A1 (en) *	2004-02-05	2007-09-20	Hartmut Zinser	Method for Producing Sodium Fosphenytoin
CH696765A5 (de) *	2004-06-02	2007-11-30	Cilag Ltd	Verfahren zur Herstellung von Natrium-fosphenytoin.
DE102004046356A1 (de) *	2004-09-24	2006-03-30	Clariant Gmbh	Verfahren zur Herstellung von Alk(en)ylphosphorsäureestersalzen
CA2937222C (en) *	2009-06-25	2019-06-04	Alkermes Pharma Ireland Limited	Prodrugs of nh-acidic compounds
ES3031438T3 (en)	2009-06-25	2025-07-08	Alkermes Pharma Ireland Ltd	Heterocyclic compounds for the treatment of neurological and psychological disorders
WO2013088255A1 (en)	2011-12-15	2013-06-20	Alkermes Pharma Ireland Limited	Prodrugs of secondary amine compounds
JP6861430B2 (ja) *	2016-09-29	2021-04-21	ノーベルファーマ株式会社	ホスフェニトインナトリウム水和物及びその合成中間体の製法
CA3092335A1 (en)	2018-03-05	2019-09-12	Alkermes Pharma Ireland Limited	Aripiprazole dosing strategy

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
BE489216A (da) *	1948-06-05	1900-01-01
US3741978A (en) *	1971-04-21	1973-06-26	Hercules Inc	Certain o,o-di (c1 and c2 alkyl) phosphorodithioate and phosphorothioate esters useful as insecticides and acaricides
US3925406A (en) *	1972-04-04	1975-12-09	Ciba Geigy Corp	Dialkoxyphosphonomethyl derivatives of hydantoins
NL7310784A (da) *	1972-08-10	1974-02-12
CH573948A5 (da) *	1972-12-12	1976-03-31	Ciba Geigy Ag
US4260769A (en) *	1977-04-22	1981-04-07	Interx Research Corporation	5,5-Diphenylhydantoins
DE3126390A1 (de) *	1981-07-03	1983-01-13	Bayer Ag, 5090 Leverkusen	S-azolyl-methyl-di(tri)-thiophosphorsaeureester, verfahren zu ihrer herstellung und ihre verwendung als schaedlingsbekaempfungsmittel
US4925860A (en) *	1987-08-05	1990-05-15	E. I. Du Pont De Nemours And Company	Stable pharmaceutical composition of 3-(hydroxymethyl)-5,5-diphenylhydantoin disodium phosphate ester
ES2169375T3 (es)	1996-04-30	2002-07-01	Warner Lambert Co	Proceso mejorado para la sintesis de diesteres del ester 2,5-dioxo-4,4-difenil-imidazolidin-1-ilmetilico de acido fosforico.

1997
- 1997-04-01 ES ES97917765T patent/ES2169375T3/es not_active Expired - Lifetime
- 1997-04-01 US US09/171,259 patent/US6022975A/en not_active Expired - Fee Related
- 1997-04-01 JP JP53889197A patent/JP4035642B2/ja not_active Expired - Fee Related
- 1997-04-01 AU AU26009/97A patent/AU708127B2/en not_active Ceased
- 1997-04-01 EP EP97917765A patent/EP0900227B1/en not_active Expired - Lifetime
- 1997-04-01 WO PCT/US1997/005307 patent/WO1997041132A1/en not_active Ceased
- 1997-04-01 SI SI9730227T patent/SI0900227T1/xx unknown
- 1997-04-01 PT PT97917765T patent/PT900227E/pt unknown
- 1997-04-01 KR KR10-1998-0708702A patent/KR100453867B1/ko not_active Expired - Fee Related
- 1997-04-01 DK DK97917765T patent/DK0900227T3/da active
- 1997-04-01 BR BRPI9709198-7A patent/BR9709198B1/pt not_active IP Right Cessation
- 1997-04-01 DE DE69709091T patent/DE69709091T2/de not_active Expired - Fee Related
- 1997-04-01 AT AT97917765T patent/ATE210670T1/de not_active IP Right Cessation
- 1997-04-01 NZ NZ332115A patent/NZ332115A/xx unknown
- 1997-04-29 ZA ZA9703713A patent/ZA973713B/xx unknown
1999
- 1999-10-25 US US09/426,433 patent/US6255492B1/en not_active Expired - Fee Related

Also Published As

Publication number	Publication date
SI0900227T1 (en)	2002-04-30
KR20000065111A (ko)	2000-11-06
US6255492B1 (en)	2001-07-03
JP4035642B2 (ja)	2008-01-23
KR100453867B1 (ko)	2005-01-15
EP0900227B1 (en)	2001-12-12
JP2000509071A (ja)	2000-07-18
US6022975A (en)	2000-02-08
ATE210670T1 (de)	2001-12-15
ES2169375T3 (es)	2002-07-01
DE69709091T2 (de)	2002-06-20
ZA973713B (en)	1997-12-01
EP0900227A1 (en)	1999-03-10
PT900227E (pt)	2002-05-31
BR9709198A (pt)	1999-08-10
AU708127B2 (en)	1999-07-29
WO1997041132A1 (en)	1997-11-06
DE69709091D1 (de)	2002-01-24
AU2600997A (en)	1997-11-19
NZ332115A (en)	2000-05-26
BR9709198B1 (pt)	2008-11-18

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