DK0902783T3 - Hydrolysefremmende, hydrofobe taxanderivater - Google Patents

Hydrolysefremmende, hydrofobe taxanderivater

Info

Publication number
DK0902783T3
DK0902783T3 DK96930847T DK96930847T DK0902783T3 DK 0902783 T3 DK0902783 T3 DK 0902783T3 DK 96930847 T DK96930847 T DK 96930847T DK 96930847 T DK96930847 T DK 96930847T DK 0902783 T3 DK0902783 T3 DK 0902783T3
Authority
DK
Denmark
Prior art keywords
hydrolysis
taxane
hydrocarbon
promoting
taxane derivatives
Prior art date
Application number
DK96930847T
Other languages
English (en)
Inventor
Eric Mayhew
Shaukat Ali
Andrew S Janoff
Original Assignee
Liposome Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Liposome Co Inc filed Critical Liposome Co Inc
Application granted granted Critical
Publication of DK0902783T3 publication Critical patent/DK0902783T3/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D305/00—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms
    • C07D305/14—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms condensed with carbocyclic rings or ring systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Dispersion Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Epoxy Compounds (AREA)
  • Medicinal Preparation (AREA)
DK96930847T 1995-09-12 1996-09-12 Hydrolysefremmende, hydrofobe taxanderivater DK0902783T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US357595P 1995-09-12 1995-09-12
PCT/US1996/014631 WO1997010234A1 (en) 1995-09-12 1996-09-12 Hydrolysis-promoting taxane hydrophobic derivatives

Publications (1)

Publication Number Publication Date
DK0902783T3 true DK0902783T3 (da) 2002-07-22

Family

ID=21706522

Family Applications (2)

Application Number Title Priority Date Filing Date
DK96930847T DK0902783T3 (da) 1995-09-12 1996-09-12 Hydrolysefremmende, hydrofobe taxanderivater
DK02008590T DK1229030T3 (da) 1995-09-12 1996-09-12 Hydrolysefremmende, hydrofobe taxanderivater

Family Applications After (1)

Application Number Title Priority Date Filing Date
DK02008590T DK1229030T3 (da) 1995-09-12 1996-09-12 Hydrolysefremmende, hydrofobe taxanderivater

Country Status (21)

Country Link
US (1) US5703117A (da)
EP (1) EP0902783B1 (da)
JP (1) JP4192208B2 (da)
KR (1) KR100401220B1 (da)
CN (1) CN1100770C (da)
AT (2) ATE216377T1 (da)
CA (1) CA2231750C (da)
CZ (1) CZ288562B6 (da)
DE (2) DE69620802T2 (da)
DK (2) DK0902783T3 (da)
ES (2) ES2252347T3 (da)
HU (1) HU226325B1 (da)
IL (1) IL123595A (da)
MX (1) MX9801871A (da)
NO (1) NO319521B1 (da)
NZ (1) NZ318300A (da)
PL (1) PL187738B1 (da)
PT (1) PT902783E (da)
SK (1) SK283199B6 (da)
TR (1) TR199800443T1 (da)
WO (1) WO1997010234A1 (da)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6107332A (en) * 1995-09-12 2000-08-22 The Liposome Company, Inc. Hydrolysis-promoting hydrophobic taxane derivatives
US6667053B1 (en) * 1996-02-16 2003-12-23 Elan Pharmaceuticals, Inc. D and L etherlipid stereoisomers and liposomes
US5912264A (en) * 1997-03-03 1999-06-15 Bristol-Myers Squibb Company 6-halo-or nitrate-substituted paclitaxels
US8853260B2 (en) 1997-06-27 2014-10-07 Abraxis Bioscience, Llc Formulations of pharmacological agents, methods for the preparation thereof and methods for the use thereof
IL136051A0 (en) * 1997-11-10 2001-05-20 Sloan Kettering Inst Cancer Process for producing arsenic trioxide formulations and methods for treating cancer using arsenic trioxide or melarsoprol
PL344327A1 (en) * 1998-05-20 2001-10-22 Liposome Co Inc Novel particulate formulations
US7314637B1 (en) 1999-06-29 2008-01-01 Neopharm, Inc. Method of administering liposomal encapsulated taxane
US6146659A (en) * 1998-07-01 2000-11-14 Neopharm, Inc. Method of administering liposomal encapsulated taxane
DE60004630T2 (de) * 1999-01-12 2004-06-17 Quanam Medical Corp., Santa Clara Arzneimittel und verfahren zur verabreichung von wasserunlöslichen paclitaxelderivaten
AU775373B2 (en) 1999-10-01 2004-07-29 Immunogen, Inc. Compositions and methods for treating cancer using immunoconjugates and chemotherapeutic agents
CA2410632A1 (en) 2000-06-22 2001-12-27 David S. Garvey Nitrosated and nitrosylated taxanes, compositions and methods of use
US6607689B1 (en) * 2000-08-29 2003-08-19 Micron Technology, Inc. Layer thickness control for stereolithography utilizing variable liquid elevation and laser focal length
DE60137229D1 (de) * 2001-10-22 2009-02-12 Viroblock Sa Non-phospholipid Vesikel (npLV) und ihre Verwendung in kosmetischen, therapeutischen und prophylaktischen Anwendungen
AU2002351169B2 (en) * 2001-11-26 2007-09-20 Intas Pharmaceuticals Limited Method for preparing and using polyoxyethylated castor oil in pharmaceutical compositions
WO2004002455A1 (en) * 2002-06-26 2004-01-08 Medigene Oncology Gmbh Novel method of stabilizing diagnostic and therapeutic compounds in a cationic carrier system
EA200501252A1 (ru) 2003-02-03 2006-02-24 Неофарм, Инк. Липосомальная композиция, способ ее получения и лекарственное средство на ее основе (варианты)
CN105879114A (zh) * 2005-02-18 2016-08-24 阿布拉西斯生物科学公司 用于整合入医疗装置的疏水性改善的药物
EP1871343A2 (en) * 2005-04-12 2008-01-02 Wisconsin Alumni Research Foundation Micelle composition of polymer and passenger drug
MX2010011165A (es) * 2008-04-10 2011-02-22 Abraxis Bioscience Llc Composiciones de derivados de taxano hidrofobos y sus usos.
JP2011517683A (ja) * 2008-04-10 2011-06-16 アブラクシス バイオサイエンス， エルエルシー 疎水性タキサン誘導体の組成物およびその使用
US8236329B2 (en) 2009-09-25 2012-08-07 Wisconsin Alumni Research Foundation Micelle encapsulation of therapeutic agents
CN105503844A (zh) * 2015-12-11 2016-04-20 上海大学 C-13和c-7位结构改造的紫杉醇类化合物及其制备方法
CN111004195B (zh) * 2019-12-03 2022-01-28 沈阳药科大学 卡巴他赛弱碱性衍生物及其制剂

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5278324A (en) * 1990-08-28 1994-01-11 Virginia Tech Intellectual Properties, Inc. Water soluble derivatives of taxol
US5059699A (en) * 1990-08-28 1991-10-22 Virginia Tech Intellectual Properties, Inc. Water soluble derivatives of taxol
DK1251127T3 (da) * 1992-12-23 2006-03-06 Bristol Myers Squibb Co Nye sidekædede-bærende taxaner og mellemprodukter deraf
IL108316A (en) * 1993-01-15 2006-10-31 Univ Florida State C10 taxane derivatives and pharmaceutical compositions containing them
US5580899A (en) * 1995-01-09 1996-12-03 The Liposome Company, Inc. Hydrophobic taxane derivatives

Also Published As

Publication number Publication date
US5703117A (en) 1997-12-30
IL123595A (en) 2000-10-31
HK1016169A1 (en) 1999-10-29
ATE309235T1 (de) 2005-11-15
IL123595A0 (en) 1998-10-30
DE69635428D1 (de) 2005-12-15
JP2001519755A (ja) 2001-10-23
HUP9901433A3 (en) 2001-05-28
DK1229030T3 (da) 2006-02-13
DE69620802T2 (de) 2002-10-10
CA2231750C (en) 2006-07-11
EP0902783A1 (en) 1999-03-24
PL325477A1 (en) 1998-07-20
NO981071L (no) 1998-05-12
WO1997010234A1 (en) 1997-03-20
AU6975696A (en) 1997-04-01
EP0902783B1 (en) 2002-04-17
CZ71198A3 (cs) 1998-07-15
HUP9901433A2 (hu) 2001-04-28
HU226325B1 (en) 2008-08-28
KR19990044409A (ko) 1999-06-25
CA2231750A1 (en) 1997-03-20
NO319521B1 (no) 2005-08-22
AU706290B2 (en) 1999-06-10
TR199800443T1 (xx) 1998-06-22
ES2252347T3 (es) 2006-05-16
CN1100770C (zh) 2003-02-05
ATE216377T1 (de) 2002-05-15
PT902783E (pt) 2002-09-30
NO981071D0 (no) 1998-03-11
NZ318300A (en) 1999-08-30
EP0902783A4 (da) 1999-03-24
CN1202166A (zh) 1998-12-16
MX9801871A (es) 1998-05-31
ES2179208T3 (es) 2003-01-16
SK33498A3 (en) 1998-08-05
KR100401220B1 (ko) 2004-03-20
DE69620802D1 (de) 2002-05-23
CZ288562B6 (cs) 2001-07-11
PL187738B1 (pl) 2004-09-30
JP4192208B2 (ja) 2008-12-10
SK283199B6 (sk) 2003-03-04
DE69635428T2 (de) 2006-06-14

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