DK0906301T3 - Benzofurylderivater og anvendelsen deraf - Google Patents

Benzofurylderivater og anvendelsen deraf

Info

Publication number
DK0906301T3
DK0906301T3 DK97921737T DK97921737T DK0906301T3 DK 0906301 T3 DK0906301 T3 DK 0906301T3 DK 97921737 T DK97921737 T DK 97921737T DK 97921737 T DK97921737 T DK 97921737T DK 0906301 T3 DK0906301 T3 DK 0906301T3
Authority
DK
Denmark
Prior art keywords
benzofuryl
derivatives
benzofuryl derivatives
Prior art date
Application number
DK97921737T
Other languages
English (en)
Inventor
Michael Boes
Heinz Stadler
Juergen Wichmann
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Application granted granted Critical
Publication of DK0906301T3 publication Critical patent/DK0906301T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
    • C07D307/82—Benzo [b] furans; Hydrogenated benzo [b] furans with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
    • C07D307/84—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • C07D307/85—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 2
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/34—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
    • A61K31/343—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide condensed with a carbocyclic ring, e.g. coumaran, bufuralol, befunolol, clobenfurol, amiodarone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/06—Antimigraine agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A61P25/32—Alcohol-abuse
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A61P25/34—Tobacco-abuse
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
    • C07D307/86—Benzo [b] furans; Hydrogenated benzo [b] furans with an oxygen atom directly attached in position 7

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Psychiatry (AREA)
  • Addiction (AREA)
  • Epidemiology (AREA)
  • Hospice & Palliative Care (AREA)
  • Pain & Pain Management (AREA)
  • Anesthesiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Furan Compounds (AREA)
DK97921737T 1996-05-03 1997-04-24 Benzofurylderivater og anvendelsen deraf DK0906301T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP96106990 1996-05-03
PCT/EP1997/002092 WO1997042183A1 (en) 1996-05-03 1997-04-24 Benzofuryl derivatives and their use

Publications (1)

Publication Number Publication Date
DK0906301T3 true DK0906301T3 (da) 2003-02-10

Family

ID=8222741

Family Applications (1)

Application Number Title Priority Date Filing Date
DK97921737T DK0906301T3 (da) 1996-05-03 1997-04-24 Benzofurylderivater og anvendelsen deraf

Country Status (21)

Country Link
US (1) US5955495A (da)
EP (1) EP0906301B1 (da)
JP (1) JP3148253B2 (da)
KR (1) KR100343060B1 (da)
CN (1) CN100347164C (da)
AR (1) AR006915A1 (da)
AT (1) ATE225342T1 (da)
AU (1) AU712056B2 (da)
BR (1) BR9708902A (da)
CA (1) CA2253547C (da)
CO (1) CO4940471A1 (da)
DE (1) DE69716062T2 (da)
DK (1) DK0906301T3 (da)
ES (1) ES2182070T3 (da)
HR (1) HRP970225A2 (da)
MA (1) MA24168A1 (da)
PE (1) PE64698A1 (da)
PT (1) PT906301E (da)
TR (1) TR199802206T2 (da)
WO (1) WO1997042183A1 (da)
ZA (1) ZA973708B (da)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2786184B1 (fr) * 1998-11-24 2002-09-20 Hoechst Marion Roussel Inc Nouveaux derives du benzofurane, leur procede de preparation, leur application comme medicaments et les compositions pharmaceutiques les renfermant
EP1343768A1 (en) 2000-12-20 2003-09-17 Bristol-Myers Squibb Pharma Company Aryl and aminoaryl substituted serotonin receptor agonist and antagonist ligands
FR2822463B1 (fr) 2001-03-21 2004-07-30 Lipha Derives bicycliques de guanidines et leurs applications en therapeutique
WO2003082275A1 (en) * 2002-03-29 2003-10-09 Orion Corporation Treatment of dependence and dependence related withdrawal symptoms
FR2845992B1 (fr) * 2002-10-16 2005-02-04 Pf Medicament Derives de 3-(cyclopenten-1yl)-benzyl-ou3-(cyclopenten-1yl)- heteroarylmethyl-amines et leur utilisation a titre de medicaments pour le traitement de la schizophrenie
DE10257357A1 (de) * 2002-12-09 2004-06-24 Bayer Ag Fluorhaltige Benzaldehyde
US20050261347A1 (en) * 2003-10-24 2005-11-24 Wyeth Dihydrobenzofuranyl alkanamine derivatives and methods for using same
US7435837B2 (en) * 2003-10-24 2008-10-14 Wyeth Dihydrobenzofuranyl alkanamine derivatives and methods for using same
US20050215644A1 (en) * 2004-03-19 2005-09-29 Interhealth Nutraceuticals, Inc. Methods for increasing neurotransmitter levels using hydroxycitric acid
JP5173190B2 (ja) 2004-08-25 2013-03-27 武田薬品工業株式会社 腹圧性尿失禁の予防・治療剤及びそのスクリーニング方法
PL1879573T3 (pl) 2005-05-10 2013-05-31 Incyte Holdings Corp Modulatory 2,3-dioksygenazy indoloaminy i sposoby ich zastosowania
US8450351B2 (en) 2005-12-20 2013-05-28 Incyte Corporation N-hydroxyamidinoheterocycles as modulators of indoleamine 2,3-dioxygenase
EP2727585A1 (en) 2006-05-16 2014-05-07 Takeda Pharmaceutical Company Limited In-vivo screening method
WO2008036642A2 (en) 2006-09-19 2008-03-27 Incyte Corporation N-hydroxyamidinoheterocycles as modulators of indoleamine 2,3-dioxygenase
CL2007002650A1 (es) 2006-09-19 2008-02-08 Incyte Corp Compuestos derivados de heterociclo n-hidroxiamino; composicion farmaceutica, util para tratar cancer, infecciones virales y desordenes neurodegenerativos entre otras.
CN103284991B (zh) * 2007-05-29 2015-09-09 财团法人大阪生物科学研究所 食品组合物
EP2789338A3 (en) 2007-11-15 2015-01-14 Takeda Pharmaceutical Company Limited Condensed pyridine derivate and use thereof
JP5465720B2 (ja) 2008-07-08 2014-04-09 インサイト・コーポレイション インドールアミン２，３−ジオキシゲナーゼの阻害剤としての１，２，５−オキサジアゾール
UY32940A (es) 2009-10-27 2011-05-31 Bayer Cropscience Ag Amidas sustituidas con halogenoalquilo como insecticidas y acaricidas
EP2510949A4 (en) 2009-12-11 2013-11-13 Astellas Pharma Inc THERAPEUTICS FOR FIBROMYALGIA
CN104045631A (zh) * 2013-03-13 2014-09-17 无锡万全医药技术有限公司 一种制备5-(4-(4-(5-氰基-1h-吲哚-3-基)丁基)哌嗪-1-基)苯并呋喃-2-甲酰胺的新方法
CN103360374B (zh) * 2013-07-12 2016-03-09 苏州永健生物医药有限公司 维拉唑酮及其盐的合成方法
ES2799582T3 (es) 2013-11-08 2020-12-18 Incyte Holdings Corp Proceso para la síntesis de un inhibidor de indoleamina 2,3-dioxigenasa
US20210052600A1 (en) 2017-12-27 2021-02-25 Takeda Pharmaceutical Company Limited Therapeutic agents for stress urinary incontinence and incotinence of feces
CN114315773B (zh) * 2020-09-29 2024-01-16 广东东阳光药业股份有限公司 一种哌嗪化合物及其制备方法
WO2024206712A1 (en) * 2023-03-31 2024-10-03 Tactogen Inc. Advantageous fluorobenzofurans for the treatment of mental disorders or enhancement

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4420476A (en) 1982-05-24 1983-12-13 Averst McKenna & Harrison, Inc. Benzofuro[3,2-c]pyrazol-3-amine derivatives
ES2051986T3 (es) * 1988-07-05 1994-07-01 Akzo Nv Compuestos con actividad broncodilatadora.
US5026726A (en) * 1989-12-11 1991-06-25 The University Of New Mexico Gossylic iminolactones and gossylic lactones and their anti-viral activities

Also Published As

Publication number Publication date
AU2769697A (en) 1997-11-26
US5955495A (en) 1999-09-21
CA2253547C (en) 2006-10-17
CN1217720A (zh) 1999-05-26
ATE225342T1 (de) 2002-10-15
CN100347164C (zh) 2007-11-07
KR100343060B1 (ko) 2002-09-18
ES2182070T3 (es) 2003-03-01
MA24168A1 (fr) 1997-12-31
WO1997042183A1 (en) 1997-11-13
ZA973708B (en) 1997-11-03
PT906301E (pt) 2003-02-28
AR006915A1 (es) 1999-09-29
BR9708902A (pt) 1999-08-03
DE69716062T2 (de) 2003-06-18
EP0906301B1 (en) 2002-10-02
KR20000010708A (ko) 2000-02-25
DE69716062D1 (de) 2002-11-07
AU712056B2 (en) 1999-10-28
HRP970225A2 (en) 1998-04-30
JP3148253B2 (ja) 2001-03-19
JPH11508283A (ja) 1999-07-21
PE64698A1 (es) 1998-10-27
TR199802206T2 (xx) 2001-12-21
CA2253547A1 (en) 1997-11-13
CO4940471A1 (es) 2000-07-24
EP0906301A1 (en) 1999-04-07

Similar Documents

Publication Publication Date Title
DK0906301T3 (da) Benzofurylderivater og anvendelsen deraf
NO984354D0 (no) Avisingsmiddel og anvendelse av dette
IS4481A (is) Díhýdrópyramídín og notkun þeirra
DK0815861T3 (da) Sulfonamider og anvendelse deraf
DK1454907T3 (da) Quninazolin og pyridopyrmidin-derivativer
DK0915880T3 (da) Azolotriaziner og pyrimidiner
NO961425D0 (no) 1N-alkyl-N-arylpyrimidinaminer og derivater derav
FI954681A7 (fi) Sykloalkano-indoli- ja azaindolijohdannaisia
NO990700D0 (no) Propionsyrederivater og anvendelsen herav
ATE225784T1 (de) Indan- oder dihydroindolderivate
SG91796A1 (en) N-(4-aryl-thiazol-2-yl)-sulphonamide derivatives and their use
DK0804078T3 (da) Sammensætning og anvendelse deraf
NO975439D0 (no) Ketonderivater og medisinsk anvendelse derav
BR9506832A (pt) N-pirazolilanilinas e n-pirazolilaminopiridinas
TR199800117A3 (tr) Isaksazol- ve krotonasitamid türevleri ve bunlarin kullanimi.
EE9800378A (et) Alküülaminobensotiasooli ja -bensoksasooli derivaadid
NO986174D0 (no) Triazinderivater og anvendelse derav
NO972206D0 (no) Bjelke og karosserikonstruksjon
NO964541L (no) Porphacyanin og CNC-utvidete porphyriner
DE69721846D1 (de) Hosenträger
DK1140952T3 (da) Phosphororganiske forbindelser og anvendelse heraf
NO984921D0 (no) Tienopyridinderivater og deres anvendelse
NO20003268L (no) Hyperhydrert kitikolin, fremgangsmÕte og anvendelse
NO983556D0 (no) Formulering og anvendelse
NO985928D0 (no) 19Fluor merket antracyklinon og antracyklinderivater