DK0912743T3 - Polynukleotidvaccinepræparat til behandling af luftvejs- og reproduktionssygdomme hos svin - Google Patents

Polynukleotidvaccinepræparat til behandling af luftvejs- og reproduktionssygdomme hos svin

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Publication number
DK0912743T3
DK0912743T3 DK97933745T DK97933745T DK0912743T3 DK 0912743 T3 DK0912743 T3 DK 0912743T3 DK 97933745 T DK97933745 T DK 97933745T DK 97933745 T DK97933745 T DK 97933745T DK 0912743 T3 DK0912743 T3 DK 0912743T3
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Prior art keywords
pigs
respiratory
treatment
vaccine preparation
polynucleotide vaccine
Prior art date
Application number
DK97933745T
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Danish (da)
English (en)
Inventor
Jean-Christophe Audonnet
Michel Riviere
Annabelle Bouchardon
Philippe Baudu
Original Assignee
Merial Sas
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Publication of DK0912743T3 publication Critical patent/DK0912743T3/da

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    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/12Viral antigens
    • A61K39/245Herpetoviridae, e.g. herpes simplex virus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/02Bacterial antigens
    • A61K39/102Pasteurellales, e.g. Actinobacillus, Pasteurella; Haemophilus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A61K39/23Parvoviridae, e.g. feline panleukopenia virus
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    • A61P31/12Antivirals
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    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
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    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
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    • Y10S424/815Viral vaccine for porcine species, e.g. swine

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DK97933745T 1996-07-19 1997-07-15 Polynukleotidvaccinepræparat til behandling af luftvejs- og reproduktionssygdomme hos svin DK0912743T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9609338A FR2751224B1 (fr) 1996-07-19 1996-07-19 Formule de vaccin polynucleotidique contre les pathologies respiratoires et de reproduction des porcs

Publications (1)

Publication Number Publication Date
DK0912743T3 true DK0912743T3 (da) 2006-01-30

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Application Number Title Priority Date Filing Date
DK97933745T DK0912743T3 (da) 1996-07-19 1997-07-15 Polynukleotidvaccinepræparat til behandling af luftvejs- og reproduktionssygdomme hos svin

Country Status (20)

Country Link
US (2) US6207165B1 (pt)
EP (1) EP0912743B1 (pt)
JP (1) JP2001500111A (pt)
KR (1) KR100496249B1 (pt)
CN (2) CN101121023A (pt)
AR (1) AR007864A1 (pt)
AU (1) AU735291B2 (pt)
BR (1) BR9710740A (pt)
CA (1) CA2261346C (pt)
CO (1) CO4750676A1 (pt)
DE (1) DE69734284T2 (pt)
DK (1) DK0912743T3 (pt)
ES (1) ES2251030T3 (pt)
FR (1) FR2751224B1 (pt)
HU (1) HUP9903822A3 (pt)
PL (1) PL190615B1 (pt)
RU (1) RU2305559C2 (pt)
TW (1) TW589190B (pt)
UA (2) UA77935C2 (pt)
WO (1) WO1998003658A1 (pt)

Families Citing this family (63)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU762901B2 (en) * 1996-07-19 2003-07-10 Merial Polynucleotide vaccine formula for treating porcine respiratory and reproductive diseases
EP0863151A1 (en) * 1997-02-12 1998-09-09 Akzo Nobel N.V. "Canine parvovirus dna vaccines"
CA2223029A1 (en) 1997-02-12 1998-08-12 Akzo Nobel Nv Canine parvovirus dna vaccines
FR2776294B1 (fr) * 1998-03-20 2001-06-22 Merial Sas Nouveaux circovirus porcins ; vaccins et reactifs de diagnostic
US7211379B2 (en) * 1997-10-03 2007-05-01 Merial Sas Prevention of myocarditis, abortion and intrauterine infection associated with porcine circovirus-2
US7192594B2 (en) * 1997-10-03 2007-03-20 Merial Limited Postweaning multisystemic wasting syndrome and porcine circovirus from pigs
US6517843B1 (en) 1999-08-31 2003-02-11 Merial Reduction of porcine circovirus-2 viral load with inactivated PCV-2
FR2781159B1 (fr) * 1998-07-06 2000-10-06 Merial Sas Vaccin circovirus et parvovirus porcin
FR2772047B1 (fr) 1997-12-05 2004-04-09 Ct Nat D Etudes Veterinaires E Sequence genomique et polypeptides de circovirus associe a la maladie de l'amaigrissement du porcelet (map), applications au diagnostic et a la prevention et/ou au traitement de l'infection
JP3795751B2 (ja) * 1997-12-11 2006-07-12 ユニバーシティ オブ サスカッチェワン ブタからの離乳後多全身系消耗症候群ウイルス
ES2170622B1 (es) * 1999-12-03 2004-05-16 Consejo Superior De Investigaciones Cientificas Clones y vectores infectivos derivados de coronavirus y sus aplicaciones.
FR2804028B1 (fr) * 2000-01-21 2004-06-04 Merial Sas Vaccins adn ameliores pour animaux de rente
KR20030054139A (ko) * 2001-12-24 2003-07-02 학교법인 건국대학교 돼지 오제스키병 바이러스의 gD 유전자를 포함하는재조합 발현 벡터 및 이를 이용한 DNA 백신
US7906311B2 (en) 2002-03-20 2011-03-15 Merial Limited Cotton rat lung cells for virus culture
US20060160759A1 (en) * 2002-09-28 2006-07-20 Jianzhu Chen Influenza therapeutic
EP1606419A1 (en) 2003-03-18 2005-12-21 Quantum Genetics Ireland Limited Systems and methods for improving protein and milk production of dairy herds
US7468273B2 (en) 2003-05-01 2008-12-23 Meial Limited Canine GHRH gene, polypeptides and methods of use
WO2005049794A2 (en) 2003-11-13 2005-06-02 University Of Georgia Research Foundation, Inc. Methods of characterizing infectious bursal disease virus
US7527967B2 (en) * 2003-11-25 2009-05-05 Academia Sinica Recombinant baculovirus and virus-like particle
WO2005112544A2 (en) 2004-02-19 2005-12-01 The Governors Of The University Of Alberta Leptin promoter polymorphisms and uses thereof
RS51324B (sr) 2005-04-25 2010-12-31 Merial Ltd. Vakcine protiv nipah virusa
US20080241184A1 (en) 2005-08-25 2008-10-02 Jules Maarten Minke Canine influenza vaccines
US7771995B2 (en) 2005-11-14 2010-08-10 Merial Limited Plasmid encoding human BMP-7
EP3147296A1 (en) 2005-11-14 2017-03-29 Merial, Inc. Gene therapy for renal failure
US7862821B2 (en) 2006-06-01 2011-01-04 Merial Limited Recombinant vaccine against bluetongue virus
US20080274137A1 (en) * 2007-05-02 2008-11-06 Jean Christophe Francis Audonnet DNA plasmids having improved expression and stability
UA100692C2 (ru) 2007-05-02 2013-01-25 Мериал Лимитед Днк-плазмиды, имеющие повышенную экспрессию и стабильность
EP3542815A1 (en) 2008-11-28 2019-09-25 Boehringer Ingelheim Animal Health USA Inc. Recombinant avian influenza vaccine and uses thereof
EP2414386B1 (en) 2009-04-03 2016-01-27 Merial Limited Newcastle disease virus vectored avian vaccines
US10633667B2 (en) 2009-12-28 2020-04-28 Boehringer Ingelheim Animal Health USA Inc. Recombinant NDV antigen and uses thereof
US20130197612A1 (en) 2010-02-26 2013-08-01 Jack W. Lasersohn Electromagnetic Radiation Therapy
ES2617743T3 (es) 2010-03-12 2017-06-19 Merial, Inc. Vacunas recombinantes del virus de la lengua azul y sus utilizaciones
CN102370976B (zh) * 2010-08-09 2014-06-11 中山大学 猪流感病毒和猪口蹄疫病毒的混合病毒样颗粒、制备方法和应用
CN102373181B (zh) * 2010-08-09 2014-06-11 中山大学 猪流感病毒和猪蓝耳病病毒混合病毒样颗粒、制备方法和应用
EP2611460B1 (en) 2010-08-31 2016-10-05 Merial, Inc. Newcastle disease virus vectored herpesvirus vaccines
WO2012090073A2 (en) 2010-12-30 2012-07-05 The Netherlands Cancer Institute Methods and compositions for predicting chemotherapy sensitivity
EP2694678A2 (en) 2011-04-04 2014-02-12 Netherland Cancer Institute Methods and compositions for predicting resistance to anticancer treatment
US20140296248A1 (en) 2011-04-04 2014-10-02 Stichting het Nederlands Kanker Instiuut-Antoni van Leeuwenhoek ziekenhuis Methods and compositions for predicting resistance to anticancer treatment
US9216213B2 (en) 2011-04-20 2015-12-22 Merial, Inc. Adjuvanted rabies vaccine with improved viscosity profile
WO2012149038A1 (en) 2011-04-25 2012-11-01 Advanced Bioscience Laboratories, Inc. Truncated hiv envelope proteins (env), methods and compositions related thereto
KR20140033096A (ko) 2011-05-07 2014-03-17 래보래토리오 아비-멕스, 에스.에이. 데 씨.브이. 바이러스성 벡터를 이용한 prrs에 대한 재조합 백신
BR112013030321A2 (pt) * 2011-05-27 2017-07-11 Sinovet Beijing Biotechnology Co Ltd composição de vacina, método para preparar a composição de vacina, uso da composição de vacina, método para imunizar um porco, cepa de vacina contra csfv e uso de uma célula no cultivo de uma cepa de vacina contra csfv.
CA2837582C (en) 2011-05-27 2021-03-02 Merial Limited Genetic vaccines against hendra virus and nipah virus
CA2837375C (en) 2011-06-01 2019-07-16 Merial Limited Needle-free administration of prrsv vaccines
MX350096B (es) 2011-08-12 2017-08-25 Merial Inc Preservación asistida con vacío de productos biológicos, en particular de vacunas.
WO2013093629A2 (en) 2011-12-20 2013-06-27 Netherlands Cancer Institute Modular vaccines, methods and compositions related thereto
EP3466443B1 (en) 2012-02-14 2020-12-16 Boehringer Ingelheim Animal Health USA Inc. Recombinant poxviral vectors expressing both rabies and ox40 proteins, and vaccines made therefrom
SI2814508T1 (sl) 2012-02-14 2017-10-30 Merial, Inc. Rotavirusna podenotska cepiva ter postopki njihove izdelave in uporaba
WO2013138776A1 (en) 2012-03-16 2013-09-19 Merial Limited Novel methods for providing long-term protective immunity against rabies in animals, based upon administration of replication-deficient flavivirus expressing rabies g
EP2861248B1 (en) 2012-06-13 2017-11-15 Merial, Inc. Reassortant btv and ahsv vaccines
CN102807989B (zh) * 2012-08-01 2014-04-23 中国人民解放军军事医学科学院军事兽医研究所 犬科和/或猫科动物疫病重组活载体疫苗的制备方法
HK1216006A1 (zh) 2013-03-12 2016-10-07 Boehringer Ingelheim Animal Health USA Inc. 反向遺傳學施馬倫貝格病毒疫苗組合物,和其使用方法
JP6236144B2 (ja) * 2013-05-31 2017-11-22 普莱柯生物工程股▲ふん▼有限公司 豚ヘルペスウイルス、ワクチン組成物及びその製造方法と応用
EP3049106A1 (en) 2013-09-25 2016-08-03 Zoetis Services LLC Pcv2b divergent vaccine composition and methods of use
CN105251000B (zh) * 2014-09-30 2018-12-14 普莱柯生物工程股份有限公司 猪伪狂犬病病毒疫苗组合物及其制备方法和应用
WO2016073410A1 (en) 2014-11-03 2016-05-12 Merial, Inc. Methods of using microneedle vaccine formulations to elicit in animals protective immunity against rabies virus
ES3050936T3 (en) 2015-06-23 2025-12-23 Boehringer Ingelheim Vetmedica Gmbh Prrsv minor protein-containing recombinant viral vectors and methods of making and use thereof
CN105693827B (zh) * 2015-06-29 2020-05-15 普莱柯生物工程股份有限公司 一种猪伪狂犬病病毒亚单位疫苗及其制备方法和应用
CN104998256A (zh) * 2015-07-14 2015-10-28 天津瑞普生物技术股份有限公司 一种猪用三联灭活疫苗的制备方法
WO2017031120A1 (en) 2015-08-20 2017-02-23 Merial, Inc. Fcv recombinant vaccines and uses thereof
HUE065661T2 (hu) 2015-09-29 2024-06-28 Boehringer Ingelheim Animal Health Usa Inc Kutya parvovírus (CPV) vírusszerû részecske (VLP) vakcinák és alkalmazásuk
DK3380119T3 (da) 2015-11-23 2021-11-15 Boehringer Ingelheim Animal Health Usa Inc Fmdv- og e2-fusionsproteiner og anvendelser deraf
TWI760322B (zh) 2016-01-29 2022-04-11 美商百靈佳殷格翰動物保健美國有限公司 重組腺病毒載體裝載之fmdv疫苗及其用途

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL8901651A (nl) * 1989-06-29 1991-01-16 Centraal Diergeneeskundig Inst Vaccin tegen pestivirusinfecties, zoals varkenspest; daarvoor bruikbare nucleotidesequenties en polypeptiden.
US6592873B1 (en) * 1992-10-30 2003-07-15 Iowa State University Research Foundation, Inc. Polynucleic acids isolated from a porcine reproductive and respiratory syndrome virus (PRRSV) and proteins encoded by the polynucleic acids
KR100374295B1 (ko) * 1993-02-08 2003-12-24 바이엘 코포레이션 돼지생식및호흡증후군바이러스의생육방법과백신에서그의용도
ATE475668T1 (de) * 1994-01-27 2010-08-15 Univ Massachusetts Medical Immunisierung durch impfung von dns transkriptionseinheit
US5516905A (en) * 1994-08-30 1996-05-14 University Of Massachusetts Medical Center Antibiotic compounds and methods to treat gram-positive bacterial and mycoplasmal infections
AU711915B2 (en) * 1995-12-21 1999-10-21 Dimminaco Ag Plasmid vaccine against pseudorabies virus

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AR007864A1 (es) 1999-11-24
PL331249A1 (en) 1999-07-05
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FR2751224A1 (fr) 1998-01-23
US6207165B1 (en) 2001-03-27
UA77935C2 (uk) 2007-02-15
CA2261346C (en) 2012-01-03
JP2001500111A (ja) 2001-01-09
EP0912743B1 (fr) 2005-09-28
HUP9903822A2 (hu) 2000-03-28
DE69734284D1 (de) 2006-02-09
AU3699197A (en) 1998-02-10
CN101121023A (zh) 2008-02-13
CA2261346A1 (en) 1998-01-29
KR20000065256A (ko) 2000-11-06
KR100496249B1 (ko) 2006-01-27
DE69734284T2 (de) 2006-07-13
HUP9903822A3 (en) 2010-01-28
CN1225684A (zh) 1999-08-11
WO1998003658A1 (fr) 1998-01-29
EP0912743A1 (fr) 1999-05-06
CN1329513C (zh) 2007-08-01
FR2751224B1 (fr) 1998-11-20
ES2251030T3 (es) 2006-04-16
US6576243B1 (en) 2003-06-10
UA91675C2 (ru) 2010-08-25
AU735291B2 (en) 2001-07-05
RU2305559C2 (ru) 2007-09-10
TW589190B (en) 2004-06-01
PL190615B1 (pl) 2005-12-30
CO4750676A1 (es) 1999-03-31

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